Inhibition of P-glycoprotein by orange juice components, polymethoxyflavones in adriamycin-resistant human myelogenous leukemia (K562/ADM) cells

Cancer Letters

Volumn 160, Issue 1, 2000, Pages 21-28

  Ikegawa, Tomomi ^a   Ushigome, Fumihiko ^a   Koyabu, Noriko ^a   Morimoto, Satoshi ^a   Shoyama, Yukihiro ^a   Naito, Mikihiko ^b   Tsuruo, Takashi ^b   Ohtani, Hisakazu ^a   Sawada, Yasufumi ^a  

^a Department of Molecular Cancer Biology   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Cancer chemotherapy; Grapefruit juice; Methoxyflavone; Multidrug resistance; Orange juice; Vincristine

Indexed keywords

CITRUS FRUIT EXTRACT; GLYCOPROTEIN P; VINCRISTINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CELL STRAIN K 562; CONTROLLED STUDY; DRUG ACCUMULATION; FRUIT JUICE; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; MYELOID LEUKEMIA; PRIORITY JOURNAL;

ACETATES; BEVERAGES; BLOTTING, WESTERN; CITRUS; COMPARATIVE STUDY; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FLAVONES; HUMAN; K562 CELLS; LEUKEMIA, MYELOID, CHRONIC; P-GLYCOPROTEINS; PLANT EXTRACTS; PSORALENS; TRITIUM; VERAPAMIL; VINCRISTINE;

EID: 0034634749     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(00)00549-8     Document Type: Article

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