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Volumn 60, Issue 6, 2000, Pages 1561-1570

Constitutive expression of insulin-like growth factor-1 in epidermal basal cells of transgenic mice leads to spontaneous tumor promotion

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SOMATOMEDIN C;

EID: 0034653704     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (159)

References (41)
  • 1
    • 0028890744 scopus 로고
    • The insulin-like growth factor 1 receptor: A key to tumor growth?
    • Baserga, R. The insulin-like growth factor 1 receptor: a key to tumor growth? Cancer Res., 55: 249-252, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 249-252
    • Baserga, R.1
  • 3
    • 0028958031 scopus 로고
    • Insulin-like growth factors and their binding proteins: Biological actions
    • Jones, J. I., and Clemmons, D. R. Insulin-like growth factors and their binding proteins: biological actions. Endocr. Rev., 16: 3-34, 1995.
    • (1995) Endocr. Rev. , vol.16 , pp. 3-34
    • Jones, J.I.1    Clemmons, D.R.2
  • 4
    • 0026316096 scopus 로고
    • Growth factors and cancer
    • Aaronson, S. A. Growth factors and cancer. Science (Washington DC), 254: 1146-1153, 1991.
    • (1991) Science (Washington DC) , vol.254 , pp. 1146-1153
    • Aaronson, S.A.1
  • 5
    • 0031196719 scopus 로고    scopus 로고
    • The insulin-like growth factor-1 receptor and apoptosis
    • Le Roith, D., Parrizas, M., and Blakesley, V. The insulin-like growth factor-1 receptor and apoptosis. Endocrine, 7: 103-105, 1998.
    • (1998) Endocrine , vol.7 , pp. 103-105
    • Le Roith, D.1    Parrizas, M.2    Blakesley, V.3
  • 6
    • 0024550730 scopus 로고
    • Analysis of insulin-like growth factor 1 gene expression in malignancy: Evidence for a paracrine role in human breast cancer
    • Yee, D., Paik, S., Lebovic, G., Marcus, R., Favoni, R., Cullen, K., Lippman, M., and Rosen, N. Analysis of insulin-like growth factor 1 gene expression in malignancy: evidence for a paracrine role in human breast cancer. Mol. Endocrinol., 3: 509-517, 1989.
    • (1989) Mol. Endocrinol. , vol.3 , pp. 509-517
    • Yee, D.1    Paik, S.2    Lebovic, G.3    Marcus, R.4    Favoni, R.5    Cullen, K.6    Lippman, M.7    Rosen, N.8
  • 7
    • 0022853272 scopus 로고
    • Enhanced levels of insulin-like growth factor messenger RNA in human colon carcinomas and liposarcomas
    • Tricoli, J., Rall, L., Karakousis, C., Herrera, L., Petrelli, N., Bell, G., and Shows, T. Enhanced levels of insulin-like growth factor messenger RNA in human colon carcinomas and liposarcomas. Cancer Res., 46: 6169-6173, 1986.
    • (1986) Cancer Res. , vol.46 , pp. 6169-6173
    • Tricoli, J.1    Rall, L.2    Karakousis, C.3    Herrera, L.4    Petrelli, N.5    Bell, G.6    Shows, T.7
  • 8
    • 0022624490 scopus 로고
    • Evidence for an increased somatomedin-C/insulin-like growth factor 1 content in primary human lung tumors
    • Minuto, F., Del Monte, P., Barreca, A., Fortini, P., Cariola, G., Catrambone, G., and Giordano, G. Evidence for an increased somatomedin-C/insulin-like growth factor 1 content in primary human lung tumors. Cancer Res., 46: 985-988, 1986.
    • (1986) Cancer Res. , vol.46 , pp. 985-988
    • Minuto, F.1    Del Monte, P.2    Barreca, A.3    Fortini, P.4    Cariola, G.5    Catrambone, G.6    Giordano, G.7
  • 10
    • 0029851189 scopus 로고    scopus 로고
    • Altered expression of insulin-like growth factor 1 and its receptor during multistage carcinogenesis in mouse skin
    • Rho, O., Bol. D., You, J., Beltran, L., Rupp, T., and DiGiovanni, J. Altered expression of insulin-like growth factor 1 and its receptor during multistage carcinogenesis in mouse skin. Mol. Carcinog., 17: 62-69, 1996.
    • (1996) Mol. Carcinog. , vol.17 , pp. 62-69
    • Rho, O.1    Bol, D.2    You, J.3    Beltran, L.4    Rupp, T.5    DiGiovanni, J.6
  • 11
    • 0025189619 scopus 로고
    • Overexpression of the human insulin-like growth factor 1 receptor promotes ligand-dependent neoplastic transformation
    • Kaleko, M., Rutter, W., and Miller, A. Overexpression of the human insulin-like growth factor 1 receptor promotes ligand-dependent neoplastic transformation. Mol. Cell. Biol., 10: 464-473, 1990.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 464-473
    • Kaleko, M.1    Rutter, W.2    Miller, A.3
  • 12
    • 0028980086 scopus 로고
    • Expression of mutant p21ras induces insulin-like growth factor 1 secretion in thyroid epithelial cells
    • Dawson, T. P., Radulescu, A., and Wynford-Thomas, D. Expression of mutant p21ras induces insulin-like growth factor 1 secretion in thyroid epithelial cells. Cancer Res., 55: 915-920, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 915-920
    • Dawson, T.P.1    Radulescu, A.2    Wynford-Thomas, D.3
  • 13
    • 0028902772 scopus 로고
    • Induction of autocrine epidermal growth factor receptor ligands in human keratinocytes by insulin/insulin-like growth factor-1
    • Vardy, D., Kari, C., Lazarus, G., Jensen, P., Zilberstein, A., Plowman, G., and Rodeck, U. Induction of autocrine epidermal growth factor receptor ligands in human keratinocytes by insulin/insulin-like growth factor-1. J. Cell. Physiol., 163: 257-265, 1995.
    • (1995) J. Cell. Physiol. , vol.163 , pp. 257-265
    • Vardy, D.1    Kari, C.2    Lazarus, G.3    Jensen, P.4    Zilberstein, A.5    Plowman, G.6    Rodeck, U.7
  • 14
    • 0027366338 scopus 로고
    • Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type-1 IGF receptor
    • Sell, C., Rubini, M., Rubin, R., Liu, J-P., Efstratiadis, A., and Baserga, R. Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type-1 IGF receptor. Proc. Natl. Acad. Sci. USA, 90: 11217-11221, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11217-11221
    • Sell, C.1    Rubini, M.2    Rubin, R.3    Liu, J.-P.4    Efstratiadis, A.5    Baserga, R.6
  • 16
    • 0030980895 scopus 로고    scopus 로고
    • Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice
    • Bol. D., Kiguchi, K., Gimenez-Conti, I., Rupp, T., and DiGiovanni, J. Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice. Oncogene, 14: 1725-1734, 1997.
    • (1997) Oncogene , vol.14 , pp. 1725-1734
    • Bol, D.1    Kiguchi, K.2    Gimenez-Conti, I.3    Rupp, T.4    DiGiovanni, J.5
  • 17
  • 19
    • 0027496895 scopus 로고
    • Mice carrying null mutations of the genes encoding insulin-like growth factor 1 and type 1 IGF receptor
    • Liu, J-P., Baker, J., Perkins, A., Robertson, E., and Efstratiadis, A. Mice carrying null mutations of the genes encoding insulin-like growth factor 1 and type 1 IGF receptor. Cell, 75: 59-72, 1993.
    • (1993) Cell , vol.75 , pp. 59-72
    • Liu, J.-P.1    Baker, J.2    Perkins, A.3    Robertson, E.4    Efstratiadis, A.5
  • 21
    • 0028318189 scopus 로고
    • Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor II transgenic mice
    • Regler, C. E., Yang, D., Rossetti, L., Donohoe, J., Alt, E., Chang, C. J., Rosenfeld, R., Neely, K., and Hintz, R. Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor II transgenic mice. J. Biol. Chem., 269: 13779-13784, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 13779-13784
    • Regler, C.E.1    Yang, D.2    Rossetti, L.3    Donohoe, J.4    Alt, E.5    Chang, C.J.6    Rosenfeld, R.7    Neely, K.8    Hintz, R.9
  • 23
    • 0027973880 scopus 로고
    • Sequences 5′ of the bovine keratin 5 gene direct tissue-and cell type-specific expression of a LacZ gene in the adult and during development
    • Ramirez, A., Bravo, A., Jorcano, J. L., and Vidal, M. Sequences 5′ of the bovine keratin 5 gene direct tissue-and cell type-specific expression of a LacZ gene in the adult and during development. Differentiation, 58: 53-64, 1994.
    • (1994) Differentiation , vol.58 , pp. 53-64
    • Ramirez, A.1    Bravo, A.2    Jorcano, J.L.3    Vidal, M.4
  • 24
    • 0027997420 scopus 로고
    • Analysis of the control of expression and tissue specificity of the keratin 5 gene, characteristic of basal keratinocytes
    • Casatorres, J., Navarro, J., Blessing, M., and Jorcano, J. Analysis of the control of expression and tissue specificity of the keratin 5 gene, characteristic of basal keratinocytes. J. Biol. Chem., 32: 20489-20496, 1994.
    • (1994) J. Biol. Chem. , vol.32 , pp. 20489-20496
    • Casatorres, J.1    Navarro, J.2    Blessing, M.3    Jorcano, J.4
  • 25
    • 0031908120 scopus 로고    scopus 로고
    • Severe follicular hyperplasia and spontaneous papilloma formation in transgenic mice expressing the Neu oncogene under the control of the bovine keratin 5 promoter
    • Bol, D., Kiguchi, K., Beltrán, L., Rupp, T., Moats, S., Gimenez-Conti, I., Jorcano, J., and DiGiovanni, J. Severe follicular hyperplasia and spontaneous papilloma formation in transgenic mice expressing the Neu oncogene under the control of the bovine keratin 5 promoter. Mol. Carcinog., 21: 2-12, 1998.
    • (1998) Mol. Carcinog. , vol.21 , pp. 2-12
    • Bol, D.1    Kiguchi, K.2    Beltrán, L.3    Rupp, T.4    Moats, S.5    Gimenez-Conti, I.6    Jorcano, J.7    DiGiovanni, J.8
  • 28
    • 0023626472 scopus 로고
    • Comparison of the histological changes in the skin of DBA/2 and C57BL/6 mice following exposure to various promoting agents
    • Naito, M., Naito, Y., and DiGiovanni, J. Comparison of the histological changes in the skin of DBA/2 and C57BL/6 mice following exposure to various promoting agents. Carcinogenesis (Lond.), 8: 1807-1815, 1987.
    • (1987) Carcinogenesis (Lond.) , vol.8 , pp. 1807-1815
    • Naito, M.1    Naito, Y.2    DiGiovanni, J.3
  • 29
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.), 227: 680-685, 1970.
    • (1970) Nature (Lond.) , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 30
    • 0024601010 scopus 로고
    • PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells
    • Auger, K. R., Serunian, L. A., Soltoff, S. P., Libby, P., and Cantley, L. C. PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells. Cell, 57: 167-175, 1989.
    • (1989) Cell , vol.57 , pp. 167-175
    • Auger, K.R.1    Serunian, L.A.2    Soltoff, S.P.3    Libby, P.4    Cantley, L.C.5
  • 31
    • 0026668643 scopus 로고
    • Transgenic overexpression of transforming growth factor bypasses the need for c-Ha-ras mutations in mouse skin tumorigenesis
    • Vassar, R., Hutton, M., and Fuchs, E. Transgenic overexpression of transforming growth factor bypasses the need for c-Ha-ras mutations in mouse skin tumorigenesis. Mol. Cell. Biol., 12: 4643-4653, 1992.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 4643-4653
    • Vassar, R.1    Hutton, M.2    Fuchs, E.3
  • 32
    • 0028332305 scopus 로고
    • Epidermal expression of transforming growth factor α in transgenic mice: Induction of spontaneous and 12-0-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression
    • Wang, X-J., Greenhalgh, D., Eckhardt, J., Rothnagel, J., and Roop, D. Epidermal expression of transforming growth factor α in transgenic mice: induction of spontaneous and 12-0-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression. Mol. Carcinog., 10: 15-22, 1994.
    • (1994) Mol. Carcinog. , vol.10 , pp. 15-22
    • Wang, X.-J.1    Greenhalgh, D.2    Eckhardt, J.3    Rothnagel, J.4    Roop, D.5
  • 33
    • 0023892187 scopus 로고
    • Epidermal papillomas and carcinomas induced in uninitiated mouse skin by tumor promoters alone contain a point mutation in the 61st codon of the Ha-ras oncogene
    • Pelling, J. C., Neades, R., and Strawhecker, J. Epidermal papillomas and carcinomas induced in uninitiated mouse skin by tumor promoters alone contain a point mutation in the 61st codon of the Ha-ras oncogene. Carcinogenesis (Lond.), 9: 665-667, 1988.
    • (1988) Carcinogenesis (Lond.) , vol.9 , pp. 665-667
    • Pelling, J.C.1    Neades, R.2    Strawhecker, J.3
  • 34
    • 0026512847 scopus 로고
    • Transplacental and transgeneration carcinogenic effect of 7,12-dimethylbenz[a]anthracene: Relationship with ras oncogene activation
    • Loktionov, A., Popovich, I., Zabezhinski, M., Martel, N., Yamasaki, H., and Tomatis, L. Transplacental and transgeneration carcinogenic effect of 7,12-dimethylbenz[a]anthracene: relationship with ras oncogene activation. Carcinogenesis (Lond.), 13: 19-24, 1992.
    • (1992) Carcinogenesis (Lond.) , vol.13 , pp. 19-24
    • Loktionov, A.1    Popovich, I.2    Zabezhinski, M.3    Martel, N.4    Yamasaki, H.5    Tomatis, L.6
  • 35
    • 0025365695 scopus 로고
    • Tissue-specific activating mutations of Ha-and Ki-ras oncogenes in skin, lung, and liver tumors induced in mice following transplacental exposures to DMBA
    • Loktionov, A., Hollstein, M., Martel, N., Galendo, D., Cabral, J., Tomatis, L., and Yamasaki, H. Tissue-specific activating mutations of Ha-and Ki-ras oncogenes in skin, lung, and liver tumors induced in mice following transplacental exposures to DMBA. Mol. Carcinog., 3: 134-140, 1990.
    • (1990) Mol. Carcinog. , vol.3 , pp. 134-140
    • Loktionov, A.1    Hollstein, M.2    Martel, N.3    Galendo, D.4    Cabral, J.5    Tomatis, L.6    Yamasaki, H.7
  • 36
    • 0027788126 scopus 로고
    • Further analysis of c-Ha-ras mutations in papillomas initiated by several polycyclic aromatic hydrocarbons or from uninitiated, promoter treated skin of SENCAR mice
    • DiGiovanni, J., Beltran, L., Rupp, A., Harvey, R. G., and Gill, R. D. Further analysis of c-Ha-ras mutations in papillomas initiated by several polycyclic aromatic hydrocarbons or from uninitiated, promoter treated skin of SENCAR mice. Mol. Carcinog., 8: 272-279, 1993.
    • (1993) Mol. Carcinog. , vol.8 , pp. 272-279
    • DiGiovanni, J.1    Beltran, L.2    Rupp, A.3    Harvey, R.G.4    Gill, R.D.5
  • 37
    • 0026729695 scopus 로고
    • Multistage carcinogenesis in mouse skin
    • DiGiovanni, J. Multistage carcinogenesis in mouse skin. Pharmacol. Ther., 48: 63-128, 1992.
    • (1992) Pharmacol. Ther. , vol.48 , pp. 63-128
    • DiGiovanni, J.1
  • 38
    • 0028085078 scopus 로고
    • The insulin signaling system
    • White, M., and Kahn, C. R. The insulin signaling system. J. Biol. Chem., 269: 1-4, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 1-4
    • White, M.1    Kahn, C.R.2
  • 40
    • 0032523237 scopus 로고    scopus 로고
    • A BCL-XL transgene promotes malignant conversion of chemically initiated skin papillomas
    • Pena, J., Rudin, C., and Thompson, C. A BCL-XL transgene promotes malignant conversion of chemically initiated skin papillomas. Cancer Res., 58: 2111-2116, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 2111-2116
    • Pena, J.1    Rudin, C.2    Thompson, C.3
  • 41
    • 0032545940 scopus 로고    scopus 로고
    • Human keratin-1.Bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation
    • Rodriguez-Villanueva, J., Greenhalgh, D., Wang, X-J., Bundman, D., Cho, S., Delehedde, M., Roop, D., and McDonnell, T. J. Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation. Oncogene, 16: 853-863, 1998.
    • (1998) Oncogene , vol.16 , pp. 853-863
    • Rodriguez-Villanueva, J.1    Greenhalgh, D.2    Wang, X.-J.3    Bundman, D.4    Cho, S.5    Delehedde, M.6    Roop, D.7    McDonnell, T.J.8


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