-
1
-
-
0026034155
-
Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage
-
Robey, E. A., B. J. Fowlkes, J. W. Gordon, D. Kioussis, H. von Boehmer, F. Ramsdell, and R. Axel. 1991. Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage. Cell 64:99.
-
(1991)
Cell
, vol.64
, pp. 99
-
-
Robey, E.A.1
Fowlkes, B.J.2
Gordon, J.W.3
Kioussis, D.4
Von Boehmer, H.5
Ramsdell, F.6
Axel, R.7
-
2
-
-
0027153897
-
Another view of the selective model of thymocyte selection
-
Chan, S. H., D. Cosgrove, C. Waltzinger, C. Benoist, and D. Mathis. 1993. Another view of the selective model of thymocyte selection. Cell 73:225.
-
(1993)
Cell
, vol.73
, pp. 225
-
-
Chan, S.H.1
Cosgrove, D.2
Waltzinger, C.3
Benoist, C.4
Mathis, D.5
-
3
-
-
0028490925
-
The different roles of MHC class recognition in thymocyte CD4 versus CD8 lineage commitment and positive selection
-
van Meerwijk, J. P., and R. N. Germain. 1994. The different roles of MHC class recognition in thymocyte CD4 versus CD8 lineage commitment and positive selection. Semin. Immunol. 6:231.
-
(1994)
Semin. Immunol.
, vol.6
, pp. 231
-
-
Van Meerwijk, J.P.1
Germain, R.N.2
-
4
-
-
0028885198
-
Role of TCR specificity in CD4 versus CD8 lineage commitment
-
Kersh, G. J., and S. M. Hedrick. 1995. Role of TCR specificity in CD4 versus CD8 lineage commitment. J. Immunol. 154:1057.
-
(1995)
J. Immunol.
, vol.154
, pp. 1057
-
-
Kersh, G.J.1
Hedrick, S.M.2
-
6
-
-
0027266755
-
Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes
-
Davis, C. B., N. Killeen, M. E. Crooks, D. Raulet, and D. R. Littman. 1993. Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes. Cell 73:237.
-
(1993)
Cell
, vol.73
, pp. 237
-
-
Davis, C.B.1
Killeen, N.2
Crooks, M.E.3
Raulet, D.4
Littman, D.R.5
-
8
-
-
0028467791
-
Functional commitment to helper T cell lineage precedes positive selection and is independent of T cell receptor MHC specificity
-
Corbella, P., D. Moskophidis, E. Spanopoulou, C. Mamalaki, M. Tolaini, A. Itano, D. Lans, D. Baltimore, E. Robey, and D. Kioussis. 1994. Functional commitment to helper T cell lineage precedes positive selection and is independent of T cell receptor MHC specificity. Immunity 1:269.
-
(1994)
Immunity
, vol.1
, pp. 269
-
-
Corbella, P.1
Moskophidis, D.2
Spanopoulou, E.3
Mamalaki, C.4
Tolaini, M.5
Itano, A.6
Lans, D.7
Baltimore, D.8
Robey, E.9
Kioussis, D.10
-
9
-
-
0030989595
-
Signals through CD8 or CD4 can induce commitment to the Cd4 lineage in the thymus
-
Bommhardt, U., M. S. Cole, J. Y. Tso, and R. Zamoyska. 1991. Signals through CD8 or CD4 can induce commitment to the CD4 lineage in the thymus. Eur. J. Immunol. 27:1152.
-
(1991)
Eur. J. Immunol.
, vol.27
, pp. 1152
-
-
Bommhardt, U.1
Cole, M.S.2
Tso, J.Y.3
Zamoyska, R.4
-
10
-
-
0032550367
-
CD3 ligation on immature thymocytes generates antagonist-like signals appropriate for CD8 lineage commitment, independently of T cell receptor specificity
-
Basson, M. A., U. Bommhardt, M. S. Cole, J. Y. Tso, and R. Zamoyska. 1998. CD3 ligation on immature thymocytes generates antagonist-like signals appropriate for CD8 lineage commitment, independently of T cell receptor specificity. J. Exp. Med. 187:1249.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1249
-
-
Basson, M.A.1
Bommhardt, U.2
Cole, M.S.3
Tso, J.Y.4
Zamoyska, R.5
-
11
-
-
0031786030
-
Molecular requirements for lineage commitment in the thymus-antibody-mediated receptor engagements reveal a central role for lck in lineage decisions
-
Basson, M. A., U. Bommhardt, P. J. Mee, V. L. Tybulewicz, and R. Zamoyska. 1998. Molecular requirements for lineage commitment in the thymus-antibody-mediated receptor engagements reveal a central role for lck in lineage decisions. Immunol. Rev. 165:181.
-
(1998)
Immunol. Rev.
, vol.165
, pp. 181
-
-
Basson, M.A.1
Bommhardt, U.2
Mee, P.J.3
Tybulewicz, V.L.4
Zamoyska, R.5
-
12
-
-
0030789066
-
+ thymocytes to the CD4 lineage requires CD3 signaling but does not require expression of clonotypic T cell receptor (TCR) chains
-
+ thymocytes to the CD4 lineage requires CD3 signaling but does not require expression of clonotypic T cell receptor (TCR) chains. J. Exp. Med. 186:17.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 17
-
-
Suzuki, H.1
Shinkai, Y.2
Granger, L.G.3
Alt, F.W.4
Love, P.E.5
Singer, A.6
-
13
-
-
0032572720
-
Csk controls antigen receptor-mediated development and selection of T-lineage cells
-
Schmedt, C., K. Saijo, T. Niidome, R. Kuhn, S. Aizawa, and A. Tarakhovsky. 1998. Csk controls antigen receptor-mediated development and selection of T-lineage cells. Nature 394:901.
-
(1998)
Nature
, vol.394
, pp. 901
-
-
Schmedt, C.1
Saijo, K.2
Niidome, T.3
Kuhn, R.4
Aizawa, S.5
Tarakhovsky, A.6
-
14
-
-
0032438114
-
Altered thymic positive selection and intracellular signals in cbl-deficient mice
-
Naramura, M., H. K. Kole, R. J. Hu, and H. Gu. 1998. Altered thymic positive selection and intracellular signals in cbl-deficient mice [In Process Citation]. Proc. Natl. Acad. Sci. USA 95:15547.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 15547
-
-
Naramura, M.1
Kole, H.K.2
Hu, R.J.3
Gu, H.4
-
16
-
-
0030297895
-
An activated form of Notch influences the choice between CD4 and CD8 T cell lineages
-
Robey, E., D. Chang, A. Itano, D. Cado, H. Alexander, D. Lans, G. Weinmaster, and P. Salmon. 1996. An activated form of Notch influences the choice between CD4 and CD8 T cell lineages. Cell 87:483.
-
(1996)
Cell
, vol.87
, pp. 483
-
-
Robey, E.1
Chang, D.2
Itano, A.3
Cado, D.4
Alexander, H.5
Lans, D.6
Weinmaster, G.7
Salmon, P.8
-
17
-
-
0032442040
-
Correlating notch signaling with thymocyte maturation
-
Deftos, M. L., Y. W. He, E. W. Ojala, and M. J. Bevan. 1998. Correlating notch signaling with thymocyte maturation. Immunity 9:777.
-
(1998)
Immunity
, vol.9
, pp. 777
-
-
Deftos, M.L.1
He, Y.W.2
Ojala, E.W.3
Bevan, M.J.4
-
18
-
-
0004068679
-
-
Blackwell Science, Malden, MA
-
Gerbart, J., and M. Kirschner. 1997. Cells, Embryos, and Evolution: Toward a Cellular and Developmental Understanding of Phenotypic Variation and Evolutionary Adaptibility. Blackwell Science, Malden, MA.
-
(1997)
Cells, Embryos, and Evolution: Toward a Cellular and Developmental Understanding of Phenotypic Variation and Evolutionary Adaptibility
-
-
Gerbart, J.1
Kirschner, M.2
-
19
-
-
0031448222
-
The influence of the MAPK pathway on T cell lineage commitment
-
Sharp, L. L., D. A. Schwarz, C. M. Bott, C. J. Marshall, and S. M. Hedrick. 1997. The influence of the MAPK pathway on T cell lineage commitment. Immunity 7:609.
-
(1997)
Immunity
, vol.7
, pp. 609
-
-
Sharp, L.L.1
Schwarz, D.A.2
Bott, C.M.3
Marshall, C.J.4
Hedrick, S.M.5
-
21
-
-
0026598333
-
Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition
-
Kaye, J., N.J. Vasquez, and S. M. Hedrick. 1992. Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition. J. Immunol. 148:3342.
-
(1992)
J. Immunol.
, vol.148
, pp. 3342
-
-
Kaye, J.1
Vasquez, N.J.2
Hedrick, S.M.3
-
22
-
-
0028178784
-
T cell receptor antagonist peptides induce positive selection
-
Hogquist, K. A., S. C. Jameson, W. R. Heath, J. L. Howard, M. J. Bevan, and F. R. Carbone. 1994. T cell receptor antagonist peptides induce positive selection. Cell 76:17.
-
(1994)
Cell
, vol.76
, pp. 17
-
-
Hogquist, K.A.1
Jameson, S.C.2
Heath, W.R.3
Howard, J.L.4
Bevan, M.J.5
Carbone, F.R.6
-
23
-
-
0025810344
-
Delayed thymocyte development induced by augmented expression of p56lck
-
Abraham, K. M., S. D. Levin, J. D. Marth, K. A. Forbush, and R. M. Perlmutter. 1991. Delayed thymocyte development induced by augmented expression of p56lck. J. Exp. Med. 173:1421.
-
(1991)
J. Exp. Med.
, vol.173
, pp. 1421
-
-
Abraham, K.M.1
Levin, S.D.2
Marth, J.D.3
Forbush, K.A.4
Perlmutter, R.M.5
-
24
-
-
0026578023
-
Identification of DNA-replicating lymphocyte subsets using a new method to label the bromo-deoxyuridine incorporated into the DNA
-
Carayon, P., and A. Bord. 1992. Identification of DNA-replicating lymphocyte subsets using a new method to label the bromo-deoxyuridine incorporated into the DNA. J. Immunol. Methods 147:225.
-
(1992)
J. Immunol. Methods
, vol.147
, pp. 225
-
-
Carayon, P.1
Bord, A.2
-
25
-
-
0032191837
-
Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes
-
Sugawara, T., T. Moriguchi, E. Nishida, and Y. Takahama. 1998. Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes. Immunity 9:565.
-
(1998)
Immunity
, vol.9
, pp. 565
-
-
Sugawara, T.1
Moriguchi, T.2
Nishida, E.3
Takahama, Y.4
-
26
-
-
0033565424
-
Activation of the extracellular signal-related kinase/mitogen-activated protein kinase pathway discriminates CD4 versus CD8 lineage commitment in the thymus
-
Bommhardt, U., M. A. Basson, U. Krummrei, and R. Zamoyska. 1999. Activation of the extracellular signal-related kinase/mitogen-activated protein kinase pathway discriminates CD4 versus CD8 lineage commitment in the thymus. J. Immunol. 163:715.
-
(1999)
J. Immunol.
, vol.163
, pp. 715
-
-
Bommhardt, U.1
Basson, M.A.2
Krummrei, U.3
Zamoyska, R.4
-
27
-
-
0030586654
-
Phorbol ester and calcium ionophore can replace TCR signals that induce positive selection of CD4 T cells
-
Takahama, Y., and H. Nakauchi. 1996. Phorbol ester and calcium ionophore can replace TCR signals that induce positive selection of CD4 T cells. J. Immunol. 157:1508.
-
(1996)
J. Immunol.
, vol.157
, pp. 1508
-
-
Takahama, Y.1
Nakauchi, H.2
-
29
-
-
0031446082
-
Pertussis toxin can replace T cell receptor signals that induce positive selection of CD8 T cells
-
Takahama, Y., Y. Tokoro, T. Sugawara, I. Negishi, and H. Nakauchi. 1997. Pertussis toxin can replace T cell receptor signals that induce positive selection of CD8 T cells. Eur. J. Immunol. 27:3318.
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 3318
-
-
Takahama, Y.1
Tokoro, Y.2
Sugawara, T.3
Negishi, I.4
Nakauchi, H.5
-
30
-
-
0025316499
-
Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans
-
Greenwald, I., and G. Seydoux. 1990. Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans. Nature 346:197.
-
(1990)
Nature
, vol.346
, pp. 197
-
-
Greenwald, I.1
Seydoux, G.2
-
31
-
-
0027379699
-
lck tyrosine kinase: Basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules
-
lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules. J. Exp. Med. 178:1701.
-
(1993)
J. Exp. Med.
, vol.178
, pp. 1701
-
-
Wiest, D.L.1
Yuan, L.2
Jefferson, J.3
Benveniste, P.4
Tsokos, M.5
Klausner, R.D.6
Glimcher, L.H.7
Samelson, L.E.8
Singer, A.9
-
32
-
-
0028467792
-
A role for the cytoplasmic tail of the β chain of CD8 in thymic selection
-
Itano, A., D. Cado, F. K. Chan, and E Robey. 1994. A role for the cytoplasmic tail of the β chain of CD8 in thymic selection. Immunity 1:287.
-
(1994)
Immunity
, vol.1
, pp. 287
-
-
Itano, A.1
Cado, D.2
Chan, F.K.3
Robey, E.4
-
33
-
-
0028491183
-
CD4 and CD8 in T cell lineage commitment: Alterations induced by expression of a CD8/CD4 chimeric transgene
-
Parnes, J. R., and R. H. Seong. 1994. CD4 and CD8 in T cell lineage commitment: alterations induced by expression of a CD8/CD4 chimeric transgene. Semin. Immunol. 6:221.
-
(1994)
Semin. Immunol.
, vol.6
, pp. 221
-
-
Parnes, J.R.1
Seong, R.H.2
-
34
-
-
0030002882
-
The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells
-
Itano, A., P. Salmon, D. Kioussis, M. Tolaini, P. Corbella, and E. Robey. 1996. The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells. J. Exp. Med. 183:731.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 731
-
-
Itano, A.1
Salmon, P.2
Kioussis, D.3
Tolaini, M.4
Corbella, P.5
Robey, E.6
-
35
-
-
0031858523
-
The cytoplasmic domain of CD8 β regulates Lck kinase activation and CD8 T cell development
-
Irie, H. Y., M. S. Mong, A. Itano, M. E. Crooks, D. R. Littman, S. J. Burakoff, and E. Robey. 1998. The cytoplasmic domain of CD8 β regulates Lck kinase activation and CD8 T cell development. J. Immunol. 161:183.
-
(1998)
J. Immunol.
, vol.161
, pp. 183
-
-
Irie, H.Y.1
Mong, M.S.2
Itano, A.3
Crooks, M.E.4
Littman, D.R.5
Burakoff, S.J.6
Robey, E.7
-
36
-
-
0029988961
-
MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent
-
Matechak, E. O., N. Killeen, S. M. Hedrick, and B. J. Fowlkes. 1996. MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent. Immunity 4:337.
-
(1996)
Immunity
, vol.4
, pp. 337
-
-
Matechak, E.O.1
Killeen, N.2
Hedrick, S.M.3
Fowlkes, B.J.4
-
37
-
-
0028913113
-
lck regulates TCR expression and T cell selection
-
lck regulates TCR expression and T cell selection. Int. Immunol. 7:617.
-
(1995)
Int. Immunol.
, vol.7
, pp. 617
-
-
Ericsson, P.O.1
Teh, H.S.2
-
38
-
-
0028302767
-
The T-cell antigen receptor utilizes Lck, Raf-1, and MEK-1 for activating mitogen-activated protein kinase: Evidence for the existence of a second protein kinase C-dependent pathway in an Lck-negative Jurkat cell mutant
-
Gupta, S., A. Weiss, G. Kumar, S. Wang, and A. Nel. 1994. The T-cell antigen receptor utilizes Lck, Raf-1, and MEK-1 for activating mitogen-activated protein kinase: evidence for the existence of a second protein kinase C-dependent pathway in an Lck-negative Jurkat cell mutant. J. Biol. Chem. 269:17349.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 17349
-
-
Gupta, S.1
Weiss, A.2
Kumar, G.3
Wang, S.4
Nel, A.5
-
39
-
-
0031051776
-
lck activity in immature thymoblasts: Stimulation of the Ras/Raf/MAPK pathway
-
lck activity in immature thymoblasts: stimulation of the Ras/Raf/MAPK pathway. Int. Immunol. 9:291.
-
(1997)
Int. Immunol.
, vol.9
, pp. 291
-
-
Lin, K.1
Abraham, K.M.2
-
40
-
-
0033582440
-
The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling
-
Denny, M. F., H. C. Kaufman, A. C. Chan, and D. B. Straus. 1999. The lck SH3 domain is required for activation of the mitogen-activated protein kinase pathway but not the initiation of T-cell antigen receptor signaling. J. Biol. Chem. 274: 5146.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 5146
-
-
Denny, M.F.1
Kaufman, H.C.2
Chan, A.C.3
Straus, D.B.4
-
41
-
-
0031918006
-
Genetic evidence of a role for Lck in T-cell receptor function independent or downstream of ZAP-70/Syk protein tyrosine kinases
-
Wong, J., D. Straus, and A. C. Chan. 1998. Genetic evidence of a role for Lck in T-cell receptor function independent or downstream of ZAP-70/Syk protein tyrosine kinases. Mol. Cell. Biol. 18:2855.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2855
-
-
Wong, J.1
Straus, D.2
Chan, A.C.3
-
42
-
-
0029802684
-
Binding of human immunodeficiency virus type I to CD4 induces association of Lck and Raf-1 and activates Raf-1 by a Ras-independent pathway
-
Popik, W., and P. M. Pitha. 1996. Binding of human immunodeficiency virus type I to CD4 induces association of Lck and Raf-1 and activates Raf-1 by a Ras-independent pathway. Mol. Cell. Biol. 16:6532.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 6532
-
-
Popik, W.1
Pitha, P.M.2
-
44
-
-
0029944826
-
lck: Differential regulation by TcR cross-linking
-
lck: differential regulation by TcR cross-linking. J. Biol. Chem. 271:10054.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10054
-
-
August, A.1
Dupont, B.2
-
47
-
-
0033136717
-
Deficient T cell fate specification in mice with an induced inactivation of Notch1
-
Radtke, F., A. Wilson, G. Stark, M. Bauer, J. van Meerwijk, H. R. MacDonald, and M. Aguet. 1999. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity 10:547.
-
(1999)
Immunity
, vol.10
, pp. 547
-
-
Radtke, F.1
Wilson, A.2
Stark, G.3
Bauer, M.4
Van Meerwijk, J.5
MacDonald, H.R.6
Aguet, M.7
-
48
-
-
0032798711
-
Expression pattern of Notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: Distinct ligand-receptor interactions in intrathymic T cell development
-
Felli, M. P., M. Maroder, T. A. Mitsiadis, A. F. Campese, D. Bellavia, A. Vacca, R. S. Mann, L. Frati, U. Lendahl, A. Gulino, and I. Screpanti. 1999. Expression pattern of Notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development. Int. Immunol. 11:1017.
-
(1999)
Int. Immunol.
, vol.11
, pp. 1017
-
-
Felli, M.P.1
Maroder, M.2
Mitsiadis, T.A.3
Campese, A.F.4
Bellavia, D.5
Vacca, A.6
Mann, R.S.7
Frati, L.8
Lendahl, U.9
Gulino, A.10
Screpanti, I.11
-
50
-
-
0028859281
-
Selective requirement for MAP kinase activation in thymocyte differentiation
-
Alberola-Ila, J., K. A. Forbush, R. Seger, E. G. Krebs, and R. M. Perlmutter. 1995. Selective requirement for MAP kinase activation in thymocyte differentiation. Nature 373:620.
-
(1995)
Nature
, vol.373
, pp. 620
-
-
Alberola-Ila, J.1
Forbush, K.A.2
Seger, R.3
Krebs, E.G.4
Perlmutter, R.M.5
-
51
-
-
0031723955
-
The notch pathway intermediate HES-1 silences CD4 gene expression
-
Kim, H. K., and G. Siu. 1998. The notch pathway intermediate HES-1 silences CD4 gene expression. Mol. Cell. Biol. 18:7166.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 7166
-
-
Kim, H.K.1
Siu, G.2
-
52
-
-
0033006012
-
The regulation of CD4 and CD8 coreceptor gene expression during T cell development
-
Ellmeier, W., S. Sawada, and D. R. Littman. 1999. The regulation of CD4 and CD8 coreceptor gene expression during T cell development. Annu. Rev. Immunol. 17:523.
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 523
-
-
Ellmeier, W.1
Sawada, S.2
Littman, D.R.3
-
53
-
-
0028066834
-
A transcriptional silencer controls the developmental expression of the CD4 gene
-
Siu, G., A. L. Wurster, D. D. Duncan, T. M. Soliman, and S. M. Hedrick. 1994. A transcriptional silencer controls the developmental expression of the CD4 gene. EMBO J. 13:3570.
-
(1994)
EMBO J.
, vol.13
, pp. 3570
-
-
Siu, G.1
Wurster, A.L.2
Duncan, D.D.3
Soliman, T.M.4
Hedrick, S.M.5
-
54
-
-
0028242609
-
A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development
-
Sawada, S., J. D. Scarborough, N. Killeen, and D. R. Littman. 1994. A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development. Cell 77:917.
-
(1994)
Cell
, vol.77
, pp. 917
-
-
Sawada, S.1
Scarborough, J.D.2
Killeen, N.3
Littman, D.R.4
-
55
-
-
0027378244
-
An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye
-
Fortini, M. E., I. Rebay, L. A. Caron, and S. Artavanis-Tsakonas. 1993. An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye. Nature 365:555.
-
(1993)
Nature
, vol.365
, pp. 555
-
-
Fortini, M.E.1
Rebay, I.2
Caron, L.A.3
Artavanis-Tsakonas, S.4
|