-
2
-
-
0030014002
-
T-cell-receptor affinity and thymocyte positive selection
-
Alam, S. M., Travers, P. J., Wung, J. L., Nasholds, W., Redpath, S., Jameson, S. C. and Gascoigne, N. R. (1996) T-cell-receptor affinity and thymocyte positive selection. Nature 381, 616-620.
-
(1996)
Nature
, vol.381
, pp. 616-620
-
-
Alam, S.M.1
Travers, P.J.2
Wung, J.L.3
Nasholds, W.4
Redpath, S.5
Jameson, S.C.6
Gascoigne, N.R.7
-
3
-
-
0033082989
-
Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands
-
Alam, S. M., Davies, G. M., Lin, C. M., Zal, T., Nasholds, W., Jameson, S. C., Hogquist, K. A., Gascoigne, N. R. and Travers, P. J. (1999) Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands. Immunity 10, 227-237.
-
(1999)
Immunity
, vol.10
, pp. 227-237
-
-
Alam, S.M.1
Davies, G.M.2
Lin, C.M.3
Zal, T.4
Nasholds, W.5
Jameson, S.C.6
Hogquist, K.A.7
Gascoigne, N.R.8
Travers, P.J.9
-
4
-
-
0028859281
-
Selective requirement for MAP kinase activation in thymocyte differentiation
-
Alberola-Ila, J., Forbush, K. A., Seger, R., Krebs, E. G. and Perlmutter, R. M. (1995) Selective requirement for MAP kinase activation in thymocyte differentiation. Nature 373, 620-623.
-
(1995)
Nature
, vol.373
, pp. 620-623
-
-
Alberola-Ila, J.1
Forbush, K.A.2
Seger, R.3
Krebs, E.G.4
Perlmutter, R.M.5
-
5
-
-
0030018912
-
Positive and negative selection invoke distinct signaling pathways
-
Alberola-Ila, J., Hogquist, K. A., Swan, K. A., Bevan, M. J. and Perlmutter, R. M. (1996) Positive and negative selection invoke distinct signaling pathways. J. Exp. Med. 184, 9-18.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 9-18
-
-
Alberola-Ila, J.1
Hogquist, K.A.2
Swan, K.A.3
Bevan, M.J.4
Perlmutter, R.M.5
-
6
-
-
0031727316
-
Thymocyte selection: Not by TCR alone
-
Amsen, D. and Kruisbeek, A. M. (1998) Thymocyte selection: not by TCR alone. Immunol. Rev. 165, 209-229.
-
(1998)
Immunol. Rev.
, vol.165
, pp. 209-229
-
-
Amsen, D.1
Kruisbeek, A.M.2
-
7
-
-
0029744303
-
Cross-talk between the T cell antigen receptor and the glucocorticoid receptor regulates thymocyte development
-
Ashwell, J. D., King, L. B. and Vacchio, M. S. (1996) Cross-talk between the T cell antigen receptor and the glucocorticoid receptor regulates thymocyte development. Stem Cells 14, 490-500.
-
(1996)
Stem Cells
, vol.14
, pp. 490-500
-
-
Ashwell, J.D.1
King, L.B.2
Vacchio, M.S.3
-
8
-
-
0034049874
-
Glucocorticoids in T cell development and function
-
Ashwell, J. D., Lu, F. W. and Vacchio, M. S. (2000) Glucocorticoids in T cell development and function. Annu. Rev. Immunol. 18, 309-345.
-
(2000)
Annu. Rev. Immunol.
, vol.18
, pp. 309-345
-
-
Ashwell, J.D.1
Lu, F.W.2
Vacchio, M.S.3
-
9
-
-
0028867899
-
Immunosuppression by glucocorticoids: Inhibition of NF-kappa B activity through induction of I kappa B synthesis
-
Auphan, N., DiDonato, J. A., Rosette, C., Helmberg, A. and Karin, M. (1995) Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science 270, 286-290.
-
(1995)
Science
, vol.270
, pp. 286-290
-
-
Auphan, N.1
DiDonato, J.A.2
Rosette, C.3
Helmberg, A.4
Karin, M.5
-
10
-
-
0029971886
-
Dexamethasone inhibits the early steps of antigen receptor signaling in activated T lymphocytes
-
Baus, E., Andris, F., Dubois, P. M., Urbain, J. and Leo, O. (1996) Dexamethasone inhibits the early steps of antigen receptor signaling in activated T lymphocytes. J. Immunol. 156, 4555-4561.
-
(1996)
J. Immunol.
, vol.156
, pp. 4555-4561
-
-
Baus, E.1
Andris, F.2
Dubois, P.M.3
Urbain, J.4
Leo, O.5
-
11
-
-
0025828493
-
Transcriptional control by nuclear receptors
-
Beato, M. (1991) Transcriptional control by nuclear receptors. FASEB J. 5, 2044-2051.
-
(1991)
FASEB J.
, vol.5
, pp. 2044-2051
-
-
Beato, M.1
-
12
-
-
0029618368
-
Steroid hormone receptors: Many actors in search of a plot
-
Beato, M., Herrlich, P. and Schutz, G. (1995) Steroid hormone receptors: many actors in search of a plot. Cell 83, 851-857.
-
(1995)
Cell
, vol.83
, pp. 851-857
-
-
Beato, M.1
Herrlich, P.2
Schutz, G.3
-
14
-
-
17944381794
-
Notch1 confers a resistance to glucocorticoid-induced apoptosis on developing thymocytes by down-regulating SRG3 expression
-
Choi, Y. I., Jeon, S. H., Jang, J., Han, S., Kim, J. K., Chung, H., Lee, H. W., Chung, H. Y., Park, S. D. and Seong, R. H. (2001) Notch1 confers a resistance to glucocorticoid-induced apoptosis on developing thymocytes by down-regulating SRG3 expression. Proc. Natl. Acad. Sci. USA 98, 10267-10272.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 10267-10272
-
-
Choi, Y.I.1
Jeon, S.H.2
Jang, J.3
Han, S.4
Kim, J.K.5
Chung, H.6
Lee, H.W.7
Chung, H.Y.8
Park, S.D.9
Seong, R.H.10
-
15
-
-
0029716563
-
The biochemistry and molecular biology of glucocorticoid-induced apoptosis in the immune system
-
Cidlowski, J. A., King, K. L., Evans-Storms, R. B., Montague, J. W., Bortner, C. D. and Hughes, F. M. (1996) The biochemistry and molecular biology of glucocorticoid-induced apoptosis in the immune system. Recent Prog. Horm. Res. 51, 457-490.
-
(1996)
Recent Prog. Horm. Res.
, vol.51
, pp. 457-490
-
-
Cidlowski, J.A.1
King, K.L.2
Evans-Storms, R.B.3
Montague, J.W.4
Bortner, C.D.5
Hughes, F.M.6
-
16
-
-
0033120424
-
Dexamethasone-induced thymocyte apoptosis: Apoptotic signal involves the sequential activation of phosphoinositide-specific phospholipase C, acidic sphingomyelinase, and caspases
-
Cifone, M. G., Migliorati, G., Parroni, R., Marchetti, C., Millimaggi, D., Santoni, A. and Riccardi, C. (1999) Dexamethasone-induced thymocyte apoptosis: apoptotic signal involves the sequential activation of phosphoinositide-specific phospholipase C, acidic sphingomyelinase, and caspases. Blood 93, 2282-2296.
-
(1999)
Blood
, vol.93
, pp. 2282-2296
-
-
Cifone, M.G.1
Migliorati, G.2
Parroni, R.3
Marchetti, C.4
Millimaggi, D.5
Santoni, A.6
Riccardi, C.7
-
17
-
-
0021367846
-
Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death
-
Cohen, J. J. and Duke, R. C. (1984) Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death. J. Immunol. 132, 38-42.
-
(1984)
J. Immunol.
, vol.132
, pp. 38-42
-
-
Cohen, J.J.1
Duke, R.C.2
-
18
-
-
0027015928
-
Glucocorticoid-induced apoptosis in the thymus
-
Cohen, J. J. (1992) Glucocorticoid-induced apoptosis in the thymus. Sem. Immunol. 4, 363-369.
-
(1992)
Sem. Immunol.
, vol.4
, pp. 363-369
-
-
Cohen, J.J.1
-
19
-
-
0033400343
-
Nuclear receptors: Coactivators, corepressors and chromatin remodeling in the control of transcription
-
Collingwood, T. N., Urnov, F. D. and Wolffe, A. P. (1999) Nuclear receptors: coactivators, corepressors and chromatin remodeling in the control of transcription. J. Mol. Endocrinol. 23, 255-275.
-
(1999)
J. Mol. Endocrinol.
, vol.23
, pp. 255-275
-
-
Collingwood, T.N.1
Urnov, F.D.2
Wolffe, A.P.3
-
20
-
-
0029038051
-
T-cell receptor V-region usage and antigen specificity. The cytochrome c model system
-
Davis, M. M., McHeyzer-Williams, M. and Chien, Y. H. (1995) T-cell receptor V-region usage and antigen specificity. The cytochrome c model system. Ann. N.Y. Acad. Sci. 756, 1-11.
-
(1995)
Ann. N.Y. Acad. Sci.
, vol.756
, pp. 1-11
-
-
Davis, M.M.1
McHeyzer-Williams, M.2
Chien, Y.H.3
-
21
-
-
0032442040
-
Correlating notch signaling with thymocyte maturation
-
Deftos, M. L., He, Y. W., Ojala, E. W. and Bevan, M. J. (1998) Correlating notch signaling with thymocyte maturation. Immunity 9, 777-786.
-
(1998)
Immunity
, vol.9
, pp. 777-786
-
-
Deftos, M.L.1
He, Y.W.2
Ojala, E.W.3
Bevan, M.J.4
-
22
-
-
0034720880
-
CD3delta couples T-cell receptor signalling to ERK activation and thymocyte positive selection
-
Delgado, P., Fernandez, E., Dave, V., Kappes, D. and Alarcon, B. (2000) CD3delta couples T-cell receptor signalling to ERK activation and thymocyte positive selection. Nature 406, 426-430.
-
(2000)
Nature
, vol.406
, pp. 426-430
-
-
Delgado, P.1
Fernandez, E.2
Dave, V.3
Kappes, D.4
Alarcon, B.5
-
23
-
-
0032509479
-
Defective T cell differentiation in the absence of Jnk1
-
Dong, C., Yang, D. D., Wysk, M., Whitmarsh, A. J., Davis, R. J. and Flavell, R. A. (1998) Defective T cell differentiation in the absence of Jnk1. Science 282, 2092-2095.
-
(1998)
Science
, vol.282
, pp. 2092-2095
-
-
Dong, C.1
Yang, D.D.2
Wysk, M.3
Whitmarsh, A.J.4
Davis, R.J.5
Flavell, R.A.6
-
24
-
-
0034604093
-
JNK is required for effector T-cell function but not for T-cell activation
-
Dong, C., Yang, D. D., Tournier, C., Whitmarsh, A. J., Xu, J., Davis, R. J. and Flavell, R. A. (2000) JNK is required for effector T-cell function but not for T-cell activation. Nature 405, 91-94.
-
(2000)
Nature
, vol.405
, pp. 91-94
-
-
Dong, C.1
Yang, D.D.2
Tournier, C.3
Whitmarsh, A.J.4
Xu, J.5
Davis, R.J.6
Flavell, R.A.7
-
25
-
-
0000658866
-
Effect of pituitary adrenotropic hormone on lymphoid tissue
-
Dougherty, T. and White, A. (1943) Effect of pituitary adrenotropic hormone on lymphoid tissue. Proc. Natl. Acad. Sci. USA 53, 132-133.
-
(1943)
Proc. Natl. Acad. Sci. USA
, vol.53
, pp. 132-133
-
-
Dougherty, T.1
White, A.2
-
26
-
-
0034303371
-
RasGRP is essential for mouse thymocyte differentiation and TCR signaling
-
Dower, N. A., Stang, S. L., Bottorff, D. A., Ebinu, J. O., Dickie, P., Ostergaard, H. L. and Stone, J. C. (2000) RasGRP is essential for mouse thymocyte differentiation and TCR signaling. Nature Immunol. 1, 317-321.
-
(2000)
Nature Immunol.
, vol.1
, pp. 317-321
-
-
Dower, N.A.1
Stang, S.L.2
Bottorff, D.A.3
Ebinu, J.O.4
Dickie, P.5
Ostergaard, H.L.6
Stone, J.C.7
-
27
-
-
0031961994
-
Human IAP-like protein regulates programmed cell death downstream of Bcl-xL and cytochrome c
-
Duckett, C. S., Li, F., Wang, Y., Tomaselli, K. J., Thompson, C. B. and Armstrong, R. C. (1998) Human IAP-like protein regulates programmed cell death downstream of Bcl-xL and cytochrome c. Mol. Cell. Biol. 18, 608-615.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 608-615
-
-
Duckett, C.S.1
Li, F.2
Wang, Y.3
Tomaselli, K.J.4
Thompson, C.B.5
Armstrong, R.C.6
-
28
-
-
0028817984
-
Oxygen radical production and thiol depletion are required for Ca(2+)-mediated endogenous endonuclease activation in apoptotic thymocytes
-
Fernandez, A., Kiefer, J., Fosdick, L. and McConkey, D. J. (1995) Oxygen radical production and thiol depletion are required for Ca(2+)-mediated endogenous endonuclease activation in apoptotic thymocytes. J. Immunol. 155, 5133-5139.
-
(1995)
J. Immunol.
, vol.155
, pp. 5133-5139
-
-
Fernandez, A.1
Kiefer, J.2
Fosdick, L.3
McConkey, D.J.4
-
29
-
-
0032492846
-
Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex
-
Fryer, C. J. and Archer, T. K. (1998) Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex. Nature 393, 88-91.
-
(1998)
Nature
, vol.393
, pp. 88-91
-
-
Fryer, C.J.1
Archer, T.K.2
-
30
-
-
0030095793
-
Suppression of glucocorticoid-induced thymocyte apoptosis by co-culture with thymic epithelial cells
-
Gao, Y., Kinoshita, Y., Hato, F., Tominaga, K. and Tsuji, Y. (1996) Suppression of glucocorticoid-induced thymocyte apoptosis by co-culture with thymic epithelial cells. Cell. Mol. Biol. 42, 227-234.
-
(1996)
Cell. Mol. Biol.
, vol.42
, pp. 227-234
-
-
Gao, Y.1
Kinoshita, Y.2
Hato, F.3
Tominaga, K.4
Tsuji, Y.5
-
31
-
-
0035229933
-
Disruption of T cell signaling networks and development by Grb2 haploid insufficiency
-
Gong, Q., Cheng, A. M., Akk, A. M., Alberola-Ila, J., Gong, G., Pawson, T. and Chan, A. C. (2001) Disruption of T cell signaling networks and development by Grb2 haploid insufficiency. Nature Immunol. 2, 29-36.
-
(2001)
Nature Immunol.
, vol.2
, pp. 29-36
-
-
Gong, Q.1
Cheng, A.M.2
Akk, A.M.3
Alberola-Ila, J.4
Gong, G.5
Pawson, T.6
Chan, A.C.7
-
32
-
-
0028970662
-
Bcl-XL displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice
-
Grillot, D. A., Merino, R. and Nunez, G. (1995) Bcl-XL displays restricted distribution during T cell development and inhibits multiple forms of apoptosis but not clonal deletion in transgenic mice. J. Exp. Med. 182, 1973-1983.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1973-1983
-
-
Grillot, D.A.1
Merino, R.2
Nunez, G.3
-
33
-
-
0029855923
-
Tuning of activation thresholds explains flexibility in the selection and development of T cells in the thymus
-
Grossman, Z. and Singer, A. (1996) Tuning of activation thresholds explains flexibility in the selection and development of T cells in the thymus. Proc. Natl. Acad. Sci. USA 93, 14747-14752.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14747-14752
-
-
Grossman, Z.1
Singer, A.2
-
34
-
-
0028219361
-
Thymocyte apoptosis induced by elevated endogenous corticosterone levels
-
Gruber, J., Sgonc, R., Hu, Y. H., Beug, H. and Wick, G. (1994) Thymocyte apoptosis induced by elevated endogenous corticosterone levels. Eur. J. Immunol. 24, 1115-1121.
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 1115-1121
-
-
Gruber, J.1
Sgonc, R.2
Hu, Y.H.3
Beug, H.4
Wick, G.5
-
35
-
-
0032493870
-
Differential requirement for caspase 9 in apoptotic pathways in vivo
-
Hakem, R., Hakem, A., Duncan, G. S., Henderson, J. T., Woo, M., Soengas, M. S., Elia, A., de la Pompa, J. L., Kagi, D., Khoo, W., Potter, J., Yoshida, R., Kaufman, S. A., Lowe, S. W., Penninger, J. M. and Mak, T. W. (1998) Differential requirement for caspase 9 in apoptotic pathways in vivo. Cell 94, 339-352.
-
(1998)
Cell
, vol.94
, pp. 339-352
-
-
Hakem, R.1
Hakem, A.2
Duncan, G.S.3
Henderson, J.T.4
Woo, M.5
Soengas, M.S.6
Elia, A.7
De la Pompa, J.L.8
Kagi, D.9
Khoo, W.10
Potter, J.11
Yoshida, R.12
Kaufman, S.A.13
Lowe, S.W.14
Penninger, J.M.15
Mak, T.W.16
-
36
-
-
0035879346
-
Peripheral T cells become sensitive to glucocorticoid- and stress-induced apoptosis in transgenic mice overexpressing SRG3
-
Han, S., Choi, H., Ko, M. G., Choi, Y. I., Sohn, D. H., Kim, J. K., Shin, D., Chung, H., Lee, H. W., Kim, J. B., Park, S. D. and Seong, R. H. (2001) Peripheral T cells become sensitive to glucocorticoid- and stress-induced apoptosis in transgenic mice overexpressing SRG3. J. Immunol. 167, 805-810.
-
(2001)
J. Immunol.
, vol.167
, pp. 805-810
-
-
Han, S.1
Choi, H.2
Ko, M.G.3
Choi, Y.I.4
Sohn, D.H.5
Kim, J.K.6
Shin, D.7
Chung, H.8
Lee, H.W.9
Kim, J.B.10
Park, S.D.11
Seong, R.H.12
-
37
-
-
0029773904
-
Modulated expression of notch1 during thymocyte development
-
Hasserjian, R. P., Aster, J. C., Davi, F., Weinberg, D. S. and Sklar, J. (1996) Modulated expression of notch1 during thymocyte development. Blood 88, 970-976.
-
(1996)
Blood
, vol.88
, pp. 970-976
-
-
Hasserjian, R.P.1
Aster, J.C.2
Davi, F.3
Weinberg, D.S.4
Sklar, J.5
-
38
-
-
0028837242
-
Glucocorticoid-induced apoptosis of human leukemic cells is caused by the repressive function of the glucocorticoid receptor
-
Helmberg, A., Auphan, N., Caelles, C. and Karin, M. (1995) Glucocorticoid-induced apoptosis of human leukemic cells is caused by the repressive function of the glucocorticoid receptor. EMBO J. 14, 452-460.
-
(1995)
EMBO J.
, vol.14
, pp. 452-460
-
-
Helmberg, A.1
Auphan, N.2
Caelles, C.3
Karin, M.4
-
39
-
-
0018033470
-
Plasma concentrations of total and free corticosterone during development in the rat
-
Henning, S. J. (1978) Plasma concentrations of total and free corticosterone during development in the rat. Am. J. Physiol. 235, 451-456.
-
(1978)
Am. J. Physiol.
, vol.235
, pp. 451-456
-
-
Henning, S.J.1
-
40
-
-
0025835716
-
BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death
-
Hockenbery, D. M., Zutter, M., Hickey, W., Nahm, M. and Korsmeyer, S. J. (1991) BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc. Natl. Acad. Sci. USA 88, 6961-6965.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 6961-6965
-
-
Hockenbery, D.M.1
Zutter, M.2
Hickey, W.3
Nahm, M.4
Korsmeyer, S.J.5
-
41
-
-
0025925014
-
CD4+CD8+CD3high thymocytes appear transiently during ontogeny: Evidence from phenotypic and functional studies
-
Hugo, P., Boyd, R. L., Waanders, G. A. and Scollay, R. (1991) CD4+CD8+CD3high thymocytes appear transiently during ontogeny: evidence from phenotypic and functional studies. Eur. J. Immunol. 21, 2655-2660.
-
(1991)
Eur. J. Immunol.
, vol.21
, pp. 2655-2660
-
-
Hugo, P.1
Boyd, R.L.2
Waanders, G.A.3
Scollay, R.4
-
42
-
-
0027415164
-
Glucocorticoid receptor-cAMP response element-binding protein interaction and the response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids
-
Imai, E., Miner, J. N., Mitchell, J. A., Yamamoto, K. R. and Granner, D. K. (1993) Glucocorticoid receptor-cAMP response element-binding protein interaction and the response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids. J. Biol. Chem. 268, 5353-5356.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 5353-5356
-
-
Imai, E.1
Miner, J.N.2
Mitchell, J.A.3
Yamamoto, K.R.4
Granner, D.K.5
-
43
-
-
0033821409
-
Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12
-
Ito, K., Barnes, P. J. and Adcock, I. M. (2000) Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12. Mol. Cell. Biol. 20, 6891-6903.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 6891-6903
-
-
Ito, K.1
Barnes, P.J.2
Adcock, I.M.3
-
44
-
-
0035839497
-
p65-activated histone acetyltransferase activity is repressed by glucocorticoids: Mifepristone fails to recruit HDAC2 to the p65-HAT complex
-
Ito, K., Jazrawi, E., Cosio, B., Barnes, P. J. and Adcock, I. M. (2001) p65-activated histone acetyltransferase activity is repressed by glucocorticoids: mifepristone fails to recruit HDAC2 to the p65-HAT complex. J. Biol. Chem. 276, 30208-30215.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30208-30215
-
-
Ito, K.1
Jazrawi, E.2
Cosio, B.3
Barnes, P.J.4
Adcock, I.M.5
-
45
-
-
0025971637
-
Rescue of thymocytes and T cell hybridomas from glucocorticoid-induced apoptosis by stimulation via the T cell receptor/CD3 complex: A possible in vitro model for positive selection of the T cell repertoire
-
Iwata, M., Hanaoka, S. and Sato, K. (1991) Rescue of thymocytes and T cell hybridomas from glucocorticoid-induced apoptosis by stimulation via the T cell receptor/CD3 complex: a possible in vitro model for positive selection of the T cell repertoire. Eur. J. Immunol. 21, 643-648.
-
(1991)
Eur. J. Immunol.
, vol.21
, pp. 643-648
-
-
Iwata, M.1
Hanaoka, S.2
Sato, K.3
-
46
-
-
0028299785
-
Involvement of protein kinase C-epsilon in glucocorticoid-induced apoptosis in thymocytes
-
Iwata, M., Iseki, R., Sato, K., Tozawa, Y. and Ohoka, Y. (1994) Involvement of protein kinase C-epsilon in glucocorticoid-induced apoptosis in thymocytes. Int. Immunol. 6, 431-438.
-
(1994)
Int. Immunol.
, vol.6
, pp. 431-438
-
-
Iwata, M.1
Iseki, R.2
Sato, K.3
Tozawa, Y.4
Ohoka, Y.5
-
47
-
-
85025395076
-
The influence of the supradrenal gland on the thymus I. Regeneration of the thymus following double supradrenalectomy in the rat
-
Jaffe, H. (1924a) The influence of the supradrenal gland on the thymus I. Regeneration of the thymus following double supradrenalectomy in the rat. J. Exp. Med. 40, 325-341.
-
(1924)
J. Exp. Med.
, vol.40
, pp. 325-341
-
-
Jaffe, H.1
-
48
-
-
85025401429
-
The influence of the supradrenal gland on the thymus III. Stimulation of the growth of the thymus gland following double supradrenalectomy in young rats
-
Jaffe, H. (1924b) The influence of the supradrenal gland on the thymus III. Stimulation of the growth of the thymus gland following double supradrenalectomy in young rats. J. Exp. Med. 40, 753-759.
-
(1924)
J. Exp. Med.
, vol.40
, pp. 753-759
-
-
Jaffe, H.1
-
49
-
-
0034691090
-
Crosstalk pathway for inhibition of glucocorticoid-induced apoptosis by T cell receptor signaling
-
Jamieson, C. A. and Yamamoto, K. R. (2000) Crosstalk pathway for inhibition of glucocorticoid-induced apoptosis by T cell receptor signaling. Proc. Natl. Acad. Sci. USA 97, 7319-7324.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 7319-7324
-
-
Jamieson, C.A.1
Yamamoto, K.R.2
-
50
-
-
0033556251
-
Cutting edge: Protective effects of notch-1 on TCR-induced apoptosis
-
Jehn, B. M., Bielke, W., Pear, W. S. and Osborne, B. A. (1999) Cutting edge: protective effects of notch-1 on TCR-induced apoptosis. J. Immunol. 162, 635-638.
-
(1999)
J. Immunol.
, vol.162
, pp. 635-638
-
-
Jehn, B.M.1
Bielke, W.2
Pear, W.S.3
Osborne, B.A.4
-
51
-
-
0033485432
-
Specialized ability of thymic epithelial cells to mediate positive selection does not require expression of the steroidogenic enzyme p450scc
-
Jenkinson, E. J., Parnell, S., Shuttleworth, J., Owen, J. J. and Anderson, G. (1999) Specialized ability of thymic epithelial cells to mediate positive selection does not require expression of the steroidogenic enzyme p450scc. J. Immunol. 163, 5781-5785.
-
(1999)
J. Immunol.
, vol.163
, pp. 5781-5785
-
-
Jenkinson, E.J.1
Parnell, S.2
Shuttleworth, J.3
Owen, J.J.4
Anderson, G.5
-
52
-
-
0030908362
-
A new mouse gene, SRG3, related to the SWI3 of Saccharomyces cerevisiae, is required for apoptosis induced by glucocorticoids in a thymoma cell line
-
Jeon, S. H., Kang, M. G., Kim, Y. H., Jin, Y. H., Lee, C., Chung, H. Y., Kwon, H., Park, S. D. and Seong, R. H. (1997) A new mouse gene, SRG3, related to the SWI3 of Saccharomyces cerevisiae, is required for apoptosis induced by glucocorticoids in a thymoma cell line. J. Exp. Med. 185, 1827-1836.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1827-1836
-
-
Jeon, S.H.1
Kang, M.G.2
Kim, Y.H.3
Jin, Y.H.4
Lee, C.5
Chung, H.Y.6
Kwon, H.7
Park, S.D.8
Seong, R.H.9
-
53
-
-
0025015647
-
Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone
-
Jonat, C., Rahmsdorf, H. J., Park, K. K., Cato, A. C., Gebel, S., Ponta, H. and Herrlich, P. (1990) Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone. Cell 62, 1189-1204.
-
(1990)
Cell
, vol.62
, pp. 1189-1204
-
-
Jonat, C.1
Rahmsdorf, H.J.2
Park, K.K.3
Cato, A.C.4
Gebel, S.5
Ponta, H.6
Herrlich, P.7
-
54
-
-
0026598333
-
Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition
-
Kaye, J., Vasquez, N. J. and Hedrick, S. M. (1992) Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition. J. Immunol. 148, 3342-3353.
-
(1992)
J. Immunol.
, vol.148
, pp. 3342-3353
-
-
Kaye, J.1
Vasquez, N.J.2
Hedrick, S.M.3
-
55
-
-
0028806218
-
A targeted glucocorticoid receptor antisense transgene increases thymocyte apoptosis and alters thymocyte development
-
King, L. B., Vacchio, M. S., Dixon, K., Hunziker, R., Margulies, D. H. and Ashwell, J. D. (1995) A targeted glucocorticoid receptor antisense transgene increases thymocyte apoptosis and alters thymocyte development. Immunity 3, 647-656.
-
(1995)
Immunity
, vol.3
, pp. 647-656
-
-
King, L.B.1
Vacchio, M.S.2
Dixon, K.3
Hunziker, R.4
Margulies, D.H.5
Ashwell, J.D.6
-
56
-
-
0032865411
-
Conditional modulation of glucocorticoid receptor activities by CREB-binding protein (CBP) and p300
-
Kino, T., Nordeen, S. K. and Chrousos, G. P. (1999) Conditional modulation of glucocorticoid receptor activities by CREB-binding protein (CBP) and p300. J. Steroid Biochem. Mol. Biol. 70, 15-25.
-
(1999)
J. Steroid Biochem. Mol. Biol.
, vol.70
, pp. 15-25
-
-
Kino, T.1
Nordeen, S.K.2
Chrousos, G.P.3
-
57
-
-
0032493910
-
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
-
Kuida, K., Haydar, T. F., Kuan, C. Y., Gu, Y., Taya, C., Karasuyama, H., Su, M. S., Rakic, P. and Flavell, R. A. (1998) Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell 94, 325-337.
-
(1998)
Cell
, vol.94
, pp. 325-337
-
-
Kuida, K.1
Haydar, T.F.2
Kuan, C.Y.3
Gu, Y.4
Taya, C.5
Karasuyama, H.6
Su, M.S.7
Rakic, P.8
Flavell, R.A.9
-
58
-
-
0343550300
-
Glucocorticoid production in the murine thymus
-
Lechner, O., Wiegers, G. J., Oliveira-Dos-Santos, A. J., Dietrich, H., Recheis, H., Waterman, M., Boyd, R. and Wick, G. (2000) Glucocorticoid production in the murine thymus. Eur. J. Immunol. 30, 337-346.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 337-346
-
-
Lechner, O.1
Wiegers, G.J.2
Oliveira-Dos-Santos, A.J.3
Dietrich, H.4
Recheis, H.5
Waterman, M.6
Boyd, R.7
Wick, G.8
-
59
-
-
0028448483
-
Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points
-
Linette, G. P., Grusby, M. J., Hedrick, S. M., Hansen, T. H., Glimcher, L. H. and Korsmeyer, S. J. (1994) Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points. Immunity 1, 197-205.
-
(1994)
Immunity
, vol.1
, pp. 197-205
-
-
Linette, G.P.1
Grusby, M.J.2
Hedrick, S.M.3
Hansen, T.H.4
Glimcher, L.H.5
Korsmeyer, S.J.6
-
60
-
-
0027976193
-
Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77
-
Liu, Z. G., Smith, S. W., McLaughlin, K. A., Schwartz, L. M. and Osborne, B. A. (1994) Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77. Nature 367, 281-284.
-
(1994)
Nature
, vol.367
, pp. 281-284
-
-
Liu, Z.G.1
Smith, S.W.2
McLaughlin, K.A.3
Schwartz, L.M.4
Osborne, B.A.5
-
61
-
-
0034665510
-
Critical relationship between TCR signaling potential and TCR affinity during thymocyte selection
-
Love, P. E., Lee, J. and Shores, E. W. (2000) Critical relationship between TCR signaling potential and TCR affinity during thymocyte selection. J. Immunol. 165, 3080-3087.
-
(2000)
J. Immunol.
, vol.165
, pp. 3080-3087
-
-
Love, P.E.1
Lee, J.2
Shores, E.W.3
-
62
-
-
0034143917
-
Thymocyte resistance to glucocorticoids leads to antigen-specific unresponsiveness due to "holes" in the T cell repertoire
-
Lu, F. W., Yasutomo, K., Goodman, G. B., McHeyzer-Williams, L. J., McHeyzer-Williams, M. G., Germain, R. N. and Ashwell, J. D. (2000) Thymocyte resistance to glucocorticoids leads to antigen-specific unresponsiveness due to "holes" in the T cell repertoire. Immunity 12, 183-192.
-
(2000)
Immunity
, vol.12
, pp. 183-192
-
-
Lu, F.W.1
Yasutomo, K.2
Goodman, G.B.3
McHeyzer-Williams, L.J.4
McHeyzer-Williams, M.G.5
Germain, R.N.6
Ashwell, J.D.7
-
63
-
-
0029031937
-
Bclx regulates the survival of double-positive thymocytes
-
Ma, A., Pena, J. C., Chang, B., Margosian, E., Davidson, L., Alt, F. W. and Thompson, C. B. (1995) Bclx regulates the survival of double-positive thymocytes. Proc. Natl. Acad. Sci. USA 92, 4763-4767.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4763-4767
-
-
Ma, A.1
Pena, J.C.2
Chang, B.3
Margosian, E.4
Davidson, L.5
Alt, F.W.6
Thompson, C.B.7
-
64
-
-
0034464839
-
Delineation of the signaling pathways involved in glucocorticoid-induced and spontaneous apoptosis of rat thymocytes
-
Mann, C. L., Hughes, F. M., Jr. and Cidlowski, J. A. (2000) Delineation of the signaling pathways involved in glucocorticoid-induced and spontaneous apoptosis of rat thymocytes. Endocrinology 141, 528-538.
-
(2000)
Endocrinology
, vol.141
, pp. 528-538
-
-
Mann, C.L.1
Hughes F.M., Jr.2
Cidlowski, J.A.3
-
65
-
-
0035115160
-
Glucocorticoids regulate plasma membrane potential during rat thymocyte apoptosis in vivo and in vitro
-
Mann, C. L. and Cidlowski, J. A. (2001) Glucocorticoids regulate plasma membrane potential during rat thymocyte apoptosis in vivo and in vitro. Endocrinology 142, 421-429.
-
(2001)
Endocrinology
, vol.142
, pp. 421-429
-
-
Mann, C.L.1
Cidlowski, J.A.2
-
66
-
-
0033178654
-
Signals involved in thymocyte positive and negative selection
-
Mariathasan, S., Jones, R. G. and Ohashi, P. S. (1999) Signals involved in thymocyte positive and negative selection. Semin. Immunol. 11, 263-272.
-
(1999)
Semin. Immunol.
, vol.11
, pp. 263-272
-
-
Mariathasan, S.1
Jones, R.G.2
Ohashi, P.S.3
-
67
-
-
0031776415
-
Human deltex is a conserved regulator of Notch signalling
-
Matsuno, K., Eastman, D., Mitsiades, T., Quinn, A. M., Carcanciu, M. L., Ordentlich, P., Kadesch, T. and Artavanis-Tsakonas, S. (1998) Human deltex is a conserved regulator of Notch signalling. Nature Genet. 19, 74-78.
-
(1998)
Nature Genet
, vol.19
, pp. 74-78
-
-
Matsuno, K.1
Eastman, D.2
Mitsiades, T.3
Quinn, A.M.4
Carcanciu, M.L.5
Ordentlich, P.6
Kadesch, T.7
Artavanis-Tsakonas, S.8
-
68
-
-
0024507195
-
Glucocorticoids activate a suicide process in thymocytes through an elevation of cytosolic Ca2+ concentration
-
McConkey, D. J., Nicotera, P., Hartzell, P., Bellomo, G., Wyllie, A. H. and Orrenius, S. (1989) Glucocorticoids activate a suicide process in thymocytes through an elevation of cytosolic Ca2+ concentration. Arch. Biochem. Biophys. 269, 365-370.
-
(1989)
Arch. Biochem. Biophys.
, vol.269
, pp. 365-370
-
-
McConkey, D.J.1
Nicotera, P.2
Hartzell, P.3
Bellomo, G.4
Wyllie, A.H.5
Orrenius, S.6
-
69
-
-
0034464826
-
CBP (CREB binding protein) integrates NF-kappaB (nuclear factor-kappaB) and glucocorticoid receptor physical interactions and antagonism
-
McKay, L. I. and Cidlowski, J. A. (2000) CBP (CREB binding protein) integrates NF-kappaB (nuclear factor-kappaB) and glucocorticoid receptor physical interactions and antagonism. Mol. Endocrinol. 14, 1222-1234.
-
(2000)
Mol. Endocrinol.
, vol.14
, pp. 1222-1234
-
-
McKay, L.I.1
Cidlowski, J.A.2
-
70
-
-
0029123504
-
Disruption of hypothalamic-pituitary-adrenocortical system in transgenic mice expressing type II glucocorticoid receptor antisense ribonucleic acid permanently impairs T cell function: Effects on T cell trafficking and T cell responsiveness during postnatal development
-
Morale, M. C., Batticane, N., Gallo, F., Barden, N. and Marchetti, B. (1995) Disruption of hypothalamic-pituitary-adrenocortical system in transgenic mice expressing type II glucocorticoid receptor antisense ribonucleic acid permanently impairs T cell function: effects on T cell trafficking and T cell responsiveness during postnatal development. Endocrinology 136, 3949-3960.
-
(1995)
Endocrinology
, vol.136
, pp. 3949-3960
-
-
Morale, M.C.1
Batticane, N.2
Gallo, F.3
Barden, N.4
Marchetti, B.5
-
71
-
-
0015434628
-
Steroid levels in the human fetus: Cortisol and cortisone
-
Murphy, B. E. and Diez d'Aux, R. C. (1972) Steroid levels in the human fetus: cortisol and cortisone. J. Clin. Endocrinol. Metab. 35, 678-683.
-
(1972)
J. Clin. Endocrinol. Metab.
, vol.35
, pp. 678-683
-
-
Murphy, B.E.1
Diez d'Aux, R.C.2
-
72
-
-
0027527099
-
Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice
-
Nakayama, K., Negishi, I., Kuida, K., Shinkai, Y., Louie, M. C., Fields, L. E., Lucas, P. J., Stewart, V. and Alt, F. W. (1993) Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice. Science 261, 1584-1588.
-
(1993)
Science
, vol.261
, pp. 1584-1588
-
-
Nakayama, K.1
Negishi, I.2
Kuida, K.3
Shinkai, Y.4
Louie, M.C.5
Fields, L.E.6
Lucas, P.J.7
Stewart, V.8
Alt, F.W.9
-
73
-
-
0029801381
-
Raf regulates positive selection
-
O'Shea, C. C., Crompton, T., Rosewell, I. R., Hayday, A. C. and Owen, M. J. (1996) Raf regulates positive selection. Eur. J. Immunol. 26, 2350-2355.
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 2350-2355
-
-
O'Shea, C.C.1
Crompton, T.2
Rosewell, I.R.3
Hayday, A.C.4
Owen, M.J.5
-
74
-
-
1842369150
-
Glucocorticoid receptor-glucocorticoid response element binding stimulates nucleosome disruption by the SWI/SNF complex
-
Ostlund Farrants, A. K., Blomquist, P., Kwon, H. and Wrange, O. (1997) Glucocorticoid receptor-glucocorticoid response element binding stimulates nucleosome disruption by the SWI/SNF complex. Mol. Cell. Biol. 17, 895-905.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 895-905
-
-
Ostlund Farrants, A.K.1
Blomquist, P.2
Kwon, H.3
Wrange, O.4
-
75
-
-
0031594575
-
NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa
-
Oswald, F., Liptay, S., Adler, G. and Schmid, R. M. (1998) NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa. Mol. Cell. Biol. 18, 2077-2088.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2077-2088
-
-
Oswald, F.1
Liptay, S.2
Adler, G.3
Schmid, R.M.4
-
76
-
-
17144458301
-
Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice
-
Pages, G., Guerin, S., Grall, D., Bonino, F., Smith, A., Anjuere, F., Auberger, P. and Pouyssegur, J. (1999) Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice. Science 286, 1374-1377.
-
(1999)
Science
, vol.286
, pp. 1374-1377
-
-
Pages, G.1
Guerin, S.2
Grall, D.3
Bonino, F.4
Smith, A.5
Anjuere, F.6
Auberger, P.7
Pouyssegur, J.8
-
77
-
-
0032896835
-
Paracrine glucocorticoid activity produced by mouse thymic epithelial cells
-
Pazirandeh, A., Xue, Y., Rafter, I., Sjovall, J., Jondal, M. and Okret, S. (1999) Paracrine glucocorticoid activity produced by mouse thymic epithelial cells. FASEB J. 13, 893-901.
-
(1999)
FASEB J.
, vol.13
, pp. 893-901
-
-
Pazirandeh, A.1
Xue, Y.2
Rafter, I.3
Sjovall, J.4
Jondal, M.5
Okret, S.6
-
78
-
-
0030747206
-
Antagonism between Nur77 and glucocorticoid receptor for control of transcription
-
Philips, A., Maira, M., Mullick, A., Chamberland, M., Lesage, S., Hugo, P. and Drouin, J. (1997) Antagonism between Nur77 and glucocorticoid receptor for control of transcription. Mol. Cell. Biol. 17, 5952-5959.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 5952-5959
-
-
Philips, A.1
Maira, M.2
Mullick, A.3
Chamberland, M.4
Lesage, S.5
Hugo, P.6
Drouin, J.7
-
79
-
-
0021016117
-
Inhibition by sodium butyrate of enzyme induction by glucocorticoids and dibutyryl cyclic AMP. A role for the rapid form of histone acetylation
-
Plesko, M. M., Hargrove, J. L., Granner, D. K. and Chalkley, R. (1983) Inhibition by sodium butyrate of enzyme induction by glucocorticoids and dibutyryl cyclic AMP. A role for the rapid form of histone acetylation. J. Biol. Chem. 258, 13738-13744.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 13738-13744
-
-
Plesko, M.M.1
Hargrove, J.L.2
Granner, D.K.3
Chalkley, R.4
-
80
-
-
20244389684
-
Notch1 expression in early lymphopoiesis influences B versus T lineage determination
-
Pui, J. C., Allman, D., Xu, L., DeRocco, S., Karnell, F. G., Bakkour, S., Lee, J. Y., Kadesch, T., Hardy, R. R., Aster, J. C. and Pear, W. S. (1999) Notch1 expression in early lymphopoiesis influences B versus T lineage determination. Immunity 11, 299-308.
-
(1999)
Immunity
, vol.11
, pp. 299-308
-
-
Pui, J.C.1
Allman, D.2
Xu, L.3
DeRocco, S.4
Karnell, F.G.5
Bakkour, S.6
Lee, J.Y.7
Kadesch, T.8
Hardy, R.R.9
Aster, J.C.10
Pear, W.S.11
-
81
-
-
0033715726
-
Intrathymic T cell development and selection proceeds normally in the absence of glucocorticoid receptor signaling
-
Purton, J. F., Boyd, R. L., Cole, T. J. and Godfrey, D. I. (2000) Intrathymic T cell development and selection proceeds normally in the absence of glucocorticoid receptor signaling. Immunity 13, 179-186.
-
(2000)
Immunity
, vol.13
, pp. 179-186
-
-
Purton, J.F.1
Boyd, R.L.2
Cole, T.J.3
Godfrey, D.I.4
-
82
-
-
0028107237
-
Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor
-
Ray, A. and Prefontaine, K. E. (1994) Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor. Proc. Natl. Acad. Sci. USA 91, 752-756.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 752-756
-
-
Ray, A.1
Prefontaine, K.E.2
-
83
-
-
18144444807
-
DNA binding of the glucocorticoid receptor is not essential for survival
-
Reichardt, H. M., Kaestner, K. H., Tuckermann, J., Kretz, O., Wessely, O., Bock, R., Gass, P., Schmid, W., Herrlich, P., Angel, P. and Schutz, G. (1998) DNA binding of the glucocorticoid receptor is not essential for survival. Cell 93, 531-541.
-
(1998)
Cell
, vol.93
, pp. 531-541
-
-
Reichardt, H.M.1
Kaestner, K.H.2
Tuckermann, J.3
Kretz, O.4
Wessely, O.5
Bock, R.6
Gass, P.7
Schmid, W.8
Herrlich, P.9
Angel, P.10
Schutz, G.11
-
84
-
-
0032538817
-
The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes
-
Rincon, M., Whitmarsh, A., Yang, D. D., Weiss, L., Derijard, B., Jayaraj, P., Davis, R. J. and Flavell, R. A. (1998) The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes. J. Exp. Med. 188, 1817-1830.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 1817-1830
-
-
Rincon, M.1
Whitmarsh, A.2
Yang, D.D.3
Weiss, L.4
Derijard, B.5
Jayaraj, P.6
Davis, R.J.7
Flavell, R.A.8
-
85
-
-
0030297895
-
An activated form of Notch influences the choice between CD4 and CD8 T cell lineages
-
Robey, E., Chang, D., Itano, A., Cado, D., Alexander, H., Lans, D., Weinmaster, G. and Salmon, P. (1996) An activated form of Notch influences the choice between CD4 and CD8 T cell lineages. Cell 87, 483-492.
-
(1996)
Cell
, vol.87
, pp. 483-492
-
-
Robey, E.1
Chang, D.2
Itano, A.3
Cado, D.4
Alexander, H.5
Lans, D.6
Weinmaster, G.7
Salmon, P.8
-
86
-
-
0033545386
-
JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development
-
Sabapathy, K., Hu, Y., Kallunki, T., Schreiber, M., David, J. P., Jochum, W., Wagner, E. F. and Karin, M. (1999) JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development. Curr. Biol. 9, 116-125.
-
(1999)
Curr. Biol.
, vol.9
, pp. 116-125
-
-
Sabapathy, K.1
Hu, Y.2
Kallunki, T.3
Schreiber, M.4
David, J.P.5
Jochum, W.6
Wagner, E.F.7
Karin, M.8
-
88
-
-
0032979994
-
Partial blockade of T-cell differentiation during ontogeny and marked alterations of the thymic microenvironment in transgenic mice with impaired glucocorticoid receptor function
-
Sacedon, R., Vicente, A., Varas, A., Morale, M. C., Barden, N., Marchetti, B. and Zapata, A. G. (1999) Partial blockade of T-cell differentiation during ontogeny and marked alterations of the thymic microenvironment in transgenic mice with impaired glucocorticoid receptor function. J. Neuroimmunol. 98, 157-167.
-
(1999)
J. Neuroimmunol.
, vol.98
, pp. 157-167
-
-
Sacedon, R.1
Vicente, A.2
Varas, A.3
Morale, M.C.4
Barden, N.5
Marchetti, B.6
Zapata, A.G.7
-
89
-
-
0022239324
-
Serum inflammatory responses of transcortin binding activities and of total and free corticosterone and progesterone levels in developing rats: A kinetic approach
-
Savu, L., Zouaghi, H. and Nunez, E. A. (1985) Serum inflammatory responses of transcortin binding activities and of total and free corticosterone and progesterone levels in developing rats: a kinetic approach. Int. J. Tissue React. 7, 443-448.
-
(1985)
Int. J. Tissue React.
, vol.7
, pp. 443-448
-
-
Savu, L.1
Zouaghi, H.2
Nunez, E.A.3
-
90
-
-
0028879819
-
Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids
-
Scheinman, R. I., Cogswell, P. C., Lofquist, A. K. and Baldwin, A. S., Jr. (1995) Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science 270, 283-286.
-
(1995)
Science
, vol.270
, pp. 283-286
-
-
Scheinman, R.I.1
Cogswell, P.C.2
Lofquist, A.K.3
Baldwin A.S., Jr.4
-
91
-
-
0033009891
-
Selection of the T cell repertoire
-
Sebzda, E., Mariathasan, S., Ohteki, T., Jones, R., Bachmann, M. F. and Ohashi, P. S. (1999) Selection of the T cell repertoire. Ann. Rev. Immunol. 17, 829-874.
-
(1999)
Ann. Rev. Immunol.
, vol.17
, pp. 829-874
-
-
Sebzda, E.1
Mariathasan, S.2
Ohteki, T.3
Jones, R.4
Bachmann, M.F.5
Ohashi, P.S.6
-
92
-
-
0000668139
-
Thymus and adrenals in the response of the organism to injuries and intoxication
-
Selye, H. (1936) Thymus and adrenals in the response of the organism to injuries and intoxication. Br. J. Exp. Pathol. 17, 234-248.
-
(1936)
Br. J. Exp. Pathol.
, vol.17
, pp. 234-248
-
-
Selye, H.1
-
93
-
-
0025751550
-
bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
-
Sentman, C. L., Shutter, J. R., Hockenbery, D., Kanagawa, O. and Korsmeyer, S. J. (1991) bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell 67, 879-888.
-
(1991)
Cell
, vol.67
, pp. 879-888
-
-
Sentman, C.L.1
Shutter, J.R.2
Hockenbery, D.3
Kanagawa, O.4
Korsmeyer, S.J.5
-
94
-
-
0026664430
-
Inhibition of thymocyte apoptosis and negative antigenic selection in bcl-2 transgenic mice
-
Siegel, R. M., Katsumata, M., Miyashita, T., Louie, D. C., Greene, M. I. and Reed, J. C. (1992) Inhibition of thymocyte apoptosis and negative antigenic selection in bcl-2 transgenic mice. Proc. Natl. Acad. Sci. USA 89, 7003-7007.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7003-7007
-
-
Siegel, R.M.1
Katsumata, M.2
Miyashita, T.3
Louie, D.C.4
Greene, M.I.5
Reed, J.C.6
-
95
-
-
0023868553
-
Regulation of the synthesis of steroidogenic enzymes in adrenal cortical cells by ACTH
-
Simpson, E. R. and Waterman, M. R. (1988) Regulation of the synthesis of steroidogenic enzymes in adrenal cortical cells by ACTH. Annu. Rev. Physiol. 50, 427-440.
-
(1988)
Annu. Rev. Physiol.
, vol.50
, pp. 427-440
-
-
Simpson, E.R.1
Waterman, M.R.2
-
96
-
-
0029851231
-
Functional interactions between Stat5 and the glucocorticoid receptor
-
Stocklin, E., Wissler, M., Gouilleux, F. and Groner, B. (1996) Functional interactions between Stat5 and the glucocorticoid receptor. Nature 383, 726-728.
-
(1996)
Nature
, vol.383
, pp. 726-728
-
-
Stocklin, E.1
Wissler, M.2
Gouilleux, F.3
Groner, B.4
-
97
-
-
0028985017
-
Involvement of p21ras distinguishes positive and negative selection in thymocytes
-
Swan, K. A., Alberola-Ila, J., Gross, J. A., Appleby, M. W., Forbush, K. A., Thomas, J. F. and Perlmutter, R. M. (1995) Involvement of p21ras distinguishes positive and negative selection in thymocytes. EMBO J. 14, 276-285.
-
(1995)
EMBO J.
, vol.14
, pp. 276-285
-
-
Swan, K.A.1
Alberola-Ila, J.2
Gross, J.A.3
Appleby, M.W.4
Forbush, K.A.5
Thomas, J.F.6
Perlmutter, R.M.7
-
98
-
-
0029583607
-
Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H)
-
Tamura, K., Taniguchi, Y., Minoguchi, S., Sakai, T., Tun, T., Furukawa, T. and Honjo, T. (1995) Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H). Curr. Biol. 5, 1416-1423.
-
(1995)
Curr. Biol.
, vol.5
, pp. 1416-1423
-
-
Tamura, K.1
Taniguchi, Y.2
Minoguchi, S.3
Sakai, T.4
Tun, T.5
Furukawa, T.6
Honjo, T.7
-
99
-
-
0033231238
-
Mechanisms of T-cell apoptosis induced by glucocoriticoids
-
Thompson, E. (1999) Mechanisms of T-cell apoptosis induced by glucocoriticoids. Trends Endocrinol. Metab. 10, 353-358.
-
(1999)
Trends Endocrinol. Metab.
, vol.10
, pp. 353-358
-
-
Thompson, E.1
-
100
-
-
0032738430
-
Progesterone receptors in the thymus are required for thymic involution during pregnancy and for normal fertility
-
Tibbetts, T. A., DeMayo, F., Rich, S., Conneely, O. M. and O'Malley, B. W. (1999) Progesterone receptors in the thymus are required for thymic involution during pregnancy and for normal fertility. Proc. Natl. Acad. Sci. USA 96, 12021-12026.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 12021-12026
-
-
Tibbetts, T.A.1
DeMayo, F.2
Rich, S.3
Conneely, O.M.4
O'Malley, B.W.5
-
101
-
-
0028233225
-
Steroid production in the thymus: Implications for thymocyte selection
-
Vacchio, M. S., Papadopoulos, V. and Ashwell, J. D. (1994) Steroid production in the thymus: implications for thymocyte selection. J. Exp. Med. 179, 1835-1846.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1835-1846
-
-
Vacchio, M.S.1
Papadopoulos, V.2
Ashwell, J.D.3
-
102
-
-
0031011063
-
Thymus-derived glucocorticoids regulate antigen-specific positive selection
-
Vacchio, M. S. and Ashwell, J. D. (1997) Thymus-derived glucocorticoids regulate antigen-specific positive selection. J. Exp. Med. 185, 2033-2038.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 2033-2038
-
-
Vacchio, M.S.1
Ashwell, J.D.2
-
103
-
-
0033179257
-
Thymus-derived glucocorticoids set the thresholds for thymocyte selection by inhibiting TCR-mediated thymocyte activation
-
Vacchio, M. S., Lee, J. Y. and Ashwell, J. D. (1999) Thymus-derived glucocorticoids set the thresholds for thymocyte selection by inhibiting TCR-mediated thymocyte activation. J. Immunol. 163, 1327-1333.
-
(1999)
J. Immunol.
, vol.163
, pp. 1327-1333
-
-
Vacchio, M.S.1
Lee, J.Y.2
Ashwell, J.D.3
-
104
-
-
0033735544
-
Glucocorticoids and thymocyte development
-
Vacchio, M. S. and Ashwell, J. D. (2000) Glucocorticoids and thymocyte development. Semin. Immunol. 12, 475-485.
-
(2000)
Semin. Immunol.
, vol.12
, pp. 475-485
-
-
Vacchio, M.S.1
Ashwell, J.D.2
-
105
-
-
0035794295
-
Glucocorticoids attenuate T cell receptor signaling
-
Van Laethem, F., Baus, E., Smyth, L. A., Andris, F., Bex, F., Urbain, J., Kioussis, D. and Leo, O. (2001) Glucocorticoids attenuate T cell receptor signaling. J. Exp. Med. 193, 803-814.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 803-814
-
-
Van Laethem, F.1
Baus, E.2
Smyth, L.A.3
Andris, F.4
Bex, F.5
Urbain, J.6
Kioussis, D.7
Leo, O.8
-
106
-
-
0033856577
-
Recruitment of chromatin remodelling factors during gene activation via the glucocorticoid receptor N-terminal domain
-
Wallberg, A. E., Flinn, E. M., Gustafsson, J. A. and Wright, A. P. (2000) Recruitment of chromatin remodelling factors during gene activation via the glucocorticoid receptor N-terminal domain. Biochem. Soc. Trans. 28, 410-414.
-
(2000)
Biochem. Soc. Trans.
, vol.28
, pp. 410-414
-
-
Wallberg, A.E.1
Flinn, E.M.2
Gustafsson, J.A.3
Wright, A.P.4
-
107
-
-
0029952319
-
Apoptosis of nur77/N10-transgenic thymocytes involves the Fas/Fas ligand pathway
-
Weih, F., Ryseck, R. P., Chen, L. and Bravo, R. (1996) Apoptosis of nur77/N10-transgenic thymocytes involves the Fas/Fas ligand pathway. Proc. Natl. Acad. Sci. USA 93, 5533-5538.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 5533-5538
-
-
Weih, F.1
Ryseck, R.P.2
Chen, L.3
Bravo, R.4
-
108
-
-
0034598346
-
Regulation of c-Jun NH(2)-terminal kinase (Jnk) gene expression during T cell activation
-
Weiss, L., Whitmarsh, A. J., Yang, D. D., Rincon, M., Davis, R. J. and Flavell, R. A. (2000) Regulation of c-Jun NH(2)-terminal kinase (Jnk) gene expression during T cell activation. J. Exp. Med. 191, 139-146.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 139-146
-
-
Weiss, L.1
Whitmarsh, A.J.2
Yang, D.D.3
Rincon, M.4
Davis, R.J.5
Flavell, R.A.6
-
109
-
-
0034720881
-
A motif in the alphabeta T-cell receptor controls positive selection by modulating ERK activity
-
Werlen, G., Hausmann, B. and Palmer, E. (2000) A motif in the alphabeta T-cell receptor controls positive selection by modulating ERK activity. Nature 406, 422-426.
-
(2000)
Nature
, vol.406
, pp. 422-426
-
-
Werlen, G.1
Hausmann, B.2
Palmer, E.3
-
110
-
-
0034921063
-
The role of molecules that mediate apoptosis in T-cell selection
-
Williams, O. and Brady, H. J. (2001) The role of molecules that mediate apoptosis in T-cell selection. Trends Immunol. 22, 107-111.
-
(2001)
Trends Immunol.
, vol.22
, pp. 107-111
-
-
Williams, O.1
Brady, H.J.2
-
111
-
-
0018830636
-
Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
-
Wyllie, A. H. (1980) Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284, 555-556.
-
(1980)
Nature
, vol.284
, pp. 555-556
-
-
Wyllie, A.H.1
-
112
-
-
0021346318
-
Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis
-
Wyllie, A. H., Morris, R. G., Smith, A. L. and Dunlop, D. (1984) Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis. J. Pathol. 142, 67-77.
-
(1984)
J. Pathol.
, vol.142
, pp. 67-77
-
-
Wyllie, A.H.1
Morris, R.G.2
Smith, A.L.3
Dunlop, D.4
-
113
-
-
0025188132
-
Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction
-
Yang-Yen, H. F., Chambard, J. C., Sun, Y. L., Smeal, T., Schmidt, T. J., Drouin, J. and Karin, M. (1990) Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction. Cell 62, 1205-1215.
-
(1990)
Cell
, vol.62
, pp. 1205-1215
-
-
Yang-Yen, H.F.1
Chambard, J.C.2
Sun, Y.L.3
Smeal, T.4
Schmidt, T.J.5
Drouin, J.6
Karin, M.7
-
114
-
-
0032544564
-
Apaf1 is required for mitochondrial pathways of apoptosis and brain development
-
Yoshida, H., Kong, Y. Y., Yoshida, R., Elia, A. J., Hakem, A., Hakem, R., Penninger, J. M. and Mak, T. W. (1998) Apaf1 is required for mitochondrial pathways of apoptosis and brain development. Cell 94, 739-750.
-
(1998)
Cell
, vol.94
, pp. 739-750
-
-
Yoshida, H.1
Kong, Y.Y.2
Yoshida, R.3
Elia, A.J.4
Hakem, A.5
Hakem, R.6
Penninger, J.M.7
Mak, T.W.8
-
115
-
-
0025613973
-
Programmed T lymphocyte death. Cell activation- and steroid-induced pathways are mutually antagonistic
-
Zacharchuk, C. M., Mercep, M., Chakraborti, P. K., Simons, S. S., Jr. and Ashwell, J. D. (1990) Programmed T lymphocyte death. Cell activation- and steroid-induced pathways are mutually antagonistic. J. Immunol. 145, 4037-4045.
-
(1990)
J. Immunol.
, vol.145
, pp. 4037-4045
-
-
Zacharchuk, C.M.1
Mercep, M.2
Chakraborti, P.K.3
Simons S.S., Jr.4
Ashwell, J.D.5
-
116
-
-
0030667790
-
STAT3 acts as a co-activator of glucocorticoid receptor signaling
-
Zhang, Z., Jones, S., Hagood, J. S., Fuentes, N. L. and Fuller, G. M. (1997) STAT3 acts as a co-activator of glucocorticoid receptor signaling. J. Biol. Chem. 272, 30607-30610.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30607-30610
-
-
Zhang, Z.1
Jones, S.2
Hagood, J.S.3
Fuentes, N.L.4
Fuller, G.M.5
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