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Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 5, 2002, Pages 743-748

Novel, potent non-covalent thrombin inhibitors incorporating P3-lactam scaffolds

(3) Ho, Jonathan Z a Gibson, Tony S a Semple, J Edward a

a Dendreon (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; LACTAM; THROMBIN; THROMBIN INHIBITOR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; COVALENT BOND; DOG; DRUG ACTIVITY; DRUG DESIGN; DRUG POTENCY; DRUG SPECIFICITY; DRUG SYNTHESIS; DRUG TARGETING; NONHUMAN;

ANIMALS; ANTITHROMBINS; BIOLOGICAL AVAILABILITY; BLOOD COAGULATION; DOGS; LACTAMS; MOLECULAR STRUCTURE; SERINE ENDOPEPTIDASES; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPSIN;

EID: 0037060907 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(02)00010-0 Document Type: Article

Times cited : (30)

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