-
1
-
-
0018931436
-
Rate-limiting barriers to intestinal drug absorption: A review
-
Hayton, W. L. Rate-Limiting Barriers to Intestinal Drug Absorption: a Review. J. Pharmacokinet. Biopharm. 1980, 8, 321-334.
-
(1980)
J. Pharmacokinet. Biopharm.
, vol.8
, pp. 321-334
-
-
Hayton, W.L.1
-
2
-
-
0000845392
-
Drug transport across gastrointestinal epithelia
-
Johnson, L. R., Ed.; Raven Press: New York
-
Jackson, M. J. Drug Transport across Gastrointestinal Epithelia. In Physiology of the Gastrointestinal Tract, 2nd ed.; Johnson, L. R., Ed.; Raven Press: New York, 1987; pp 1597-1621.
-
(1987)
Physiology of the Gastrointestinal Tract, 2nd Ed.
, pp. 1597-1621
-
-
Jackson, M.J.1
-
3
-
-
0029782485
-
Carrier-mediated intestinal transport of drugs
-
Tsuji, A.; Takami, I. Carrier-Mediated Intestinal Transport of Drugs. Pharm. Res. 1996, 13, 963-977.
-
(1996)
Pharm. Res.
, vol.13
, pp. 963-977
-
-
Tsuji, A.1
Takami, I.2
-
4
-
-
0023612699
-
Structure, biochemistry, and assembly of epithelial tight junctions
-
Gumbiner, B. Structure, Biochemistry, and Assembly of Epithelial Tight Junctions. Am. J. Physiol. 1987, 253, C749-C758.
-
(1987)
Am. J. Physiol.
, vol.253
-
-
Gumbiner, B.1
-
5
-
-
0029167043
-
Regulation of tight-junction permeability during nutrient absorption across the intestinal epithelium
-
Ballard, S. T.; Hunter, J. H.; Taylor A. E. Regulation of Tight-Junction Permeability during Nutrient Absorption across the Intestinal Epithelium. Annu. Rev. Nutr. 1995, 15, 35-55.
-
(1995)
Annu. Rev. Nutr.
, vol.15
, pp. 35-55
-
-
Ballard, S.T.1
Hunter, J.H.2
Taylor, A.E.3
-
6
-
-
0021723835
-
Tight junctions. Their structure, composition, and function
-
Schneeberger, E. E.; Lynch, R. D. Tight Junctions. Their Structure, Composition, and Function. Circ. Res. 1984, 55, 723-733.
-
(1984)
Circ. Res.
, vol.55
, pp. 723-733
-
-
Schneeberger, E.E.1
Lynch, R.D.2
-
7
-
-
0030820929
-
Molecular structure of the apical junction complex and its contribution to the paracellular barrier
-
Lutz, K. L.; Siahaan, T. J. Molecular Structure of the Apical Junction Complex and its Contribution to the Paracellular Barrier. J. Pharm. Sci. 1997, 86, 977-984.
-
(1997)
J. Pharm. Sci.
, vol.86
, pp. 977-984
-
-
Lutz, K.L.1
Siahaan, T.J.2
-
8
-
-
0027134778
-
Mechanism of intestinal absorption of ranitidine and ondansetron transport across Caco-2 cell monolayers
-
Gan, L.-S.; Hsyu, P.-H.; Pritchard, J. F.; Thakker, D. R. Mechanism of Intestinal Absorption of Ranitidine and Ondansetron Transport across Caco-2 cell Monolayers. Pharm. Res. 1993, 10, 1722-1725.
-
(1993)
Pharm. Res.
, vol.10
, pp. 1722-1725
-
-
Gan, L.-S.1
Hsyu, P.-H.2
Pritchard, J.F.3
Thakker, D.R.4
-
9
-
-
0026099796
-
2-receptor antagonists
-
2-Receptor Antagonists. Clin. Pharmacokinet. 1991, 20, 218-236.
-
(1991)
Clin. Pharmacokinet.
, vol.20
, pp. 218-236
-
-
Lin, J.H.1
-
12
-
-
0025195255
-
Insulin regulates the paracellular permeability of cultured intestinal epithelial cell monolayers
-
McRoberts, J. A.; Aranda, R.; Riley, N.; Kang, H. Insulin Regulates the Paracellular Permeability of Cultured Intestinal Epithelial Cell Monolayers. J. Clin. Invest. 1990, 85, 1127-1134.
-
(1990)
J. Clin. Invest.
, vol.85
, pp. 1127-1134
-
-
McRoberts, J.A.1
Aranda, R.2
Riley, N.3
Kang, H.4
-
13
-
-
0021490671
-
Epithelial properties of human colonic carcinoma cell line Caco-2: Electrical properties
-
Grasset, E.; Pinto, M.; Dussaulx, E.; Zweibaum, A.; Desjeux, J.-F. Epithelial Properties of Human Colonic Carcinoma Cell Line Caco-2: Electrical Properties. Am. J. Physiol. 1984, 247, C260-C267.
-
(1984)
Am. J. Physiol.
, vol.247
-
-
Grasset, E.1
Pinto, M.2
Dussaulx, E.3
Zweibaum, A.4
Desjeux, J.-F.5
-
14
-
-
85069282971
-
-
note
-
The oral bioavailability for famotidine (40-49%), ranitidine (51-60%), cimetidine (58-66%), and nizatidine (84-112%) was determined at the oral doses of 40, 100, 300, and 150 mg, respectively; see refs 9, 10, and references therein.
-
-
-
-
15
-
-
0026712808
-
Transport of a large neutral amino acid in a human intestinal epithelial cell line (Caco-2): Uptake and efflux of phenylalanine
-
Hu, M.; Borchardt, R. T. Transport of a Large Neutral Amino Acid in a Human Intestinal Epithelial Cell Line (Caco-2): Uptake and Efflux of Phenylalanine. Biochim. Biophys. Acta 1992, 1135, 233-244.
-
(1992)
Biochim. Biophys. Acta
, vol.1135
, pp. 233-244
-
-
Hu, M.1
Borchardt, R.T.2
-
16
-
-
0027487992
-
+-coupled dipeptide (Glycylsarcosine) transport across apical and basal borders of human intestinal Caco-2 cell monolayers displays distinctive characteristics
-
+-Coupled Dipeptide (Glycylsarcosine) Transport across Apical and Basal Borders of Human Intestinal Caco-2 Cell Monolayers Displays Distinctive Characteristics. Biochim. Biophys. Acta 1993, 1151, 237-245.
-
(1993)
Biochim. Biophys. Acta
, vol.1151
, pp. 237-245
-
-
Thwaites, D.T.1
Brown, C.D.A.2
Hirst, B.H.3
Simmons, N.L.4
-
17
-
-
0026496355
-
Cefaclor uptake by the proton-dependent dipeptide transport carrier of human intestinal Caco-2 cells and comparison to cephalexin uptake
-
Dantzig, A. H.; Tabas, L. B.; Bergin, L. Cefaclor Uptake by the Proton-Dependent Dipeptide Transport Carrier of Human Intestinal Caco-2 Cells and Comparison to Cephalexin Uptake. Biochim. Biophys. Acta 1992, 1112, 167-173.
-
(1992)
Biochim. Biophys. Acta
, vol.1112
, pp. 167-173
-
-
Dantzig, A.H.1
Tabas, L.B.2
Bergin, L.3
-
18
-
-
0023579684
-
Succinate and citrate transport in renal basolateral and brush-border membranes
-
Wright, S. H.; Wunz, T. M. Succinate and Citrate Transport in Renal Basolateral and Brush-Border Membranes. Am. J. Physiol. 1987, 253, F432-F439.
-
(1987)
Am. J. Physiol.
, vol.253
-
-
Wright, S.H.1
Wunz, T.M.2
-
19
-
-
0023431945
-
2-receptor antagonists. 2. Synthesis and pharmacological activities of N-sulfamoyl and N-sulfonyl amidine derivatives
-
2-Receptor Antagonists. 2. Synthesis and Pharmacological Activities of N-Sulfamoyl and N-Sulfonyl Amidine Derivatives. J. Med. Chem. 1987, 30, 1787-1793.
-
(1987)
J. Med. Chem.
, vol.30
, pp. 1787-1793
-
-
Yanagisawa, I.1
Hirata, Y.2
Ishio, Y.3
-
20
-
-
85069279049
-
-
U.S. Patent 4, 165,-378, 1979
-
Gilman, D. J.; Wardleworth, J. M.; Yellin, O. Guanidine Derivatives of Imidazoles and Thiazoles. U.S. Patent 4, 165,-378, 1979.
-
Guanidine Derivatives of Imidazoles and Thiazoles
-
-
Gilman, D.J.1
Wardleworth, J.M.2
Yellin, O.3
-
21
-
-
0016331790
-
Blockage of cation permeability across the tight junctions of gallbladder and other leaky epithelia
-
Moreno, J. H. Blockage of Cation Permeability across the Tight Junctions of Gallbladder and Other Leaky Epithelia. Nature 1974, 251, 150-151.
-
(1974)
Nature
, vol.251
, pp. 150-151
-
-
Moreno, J.H.1
-
22
-
-
0016682656
-
Blockage of gallbladder tight junction cation-selective channels by 2,4,6-triaminopyrimidinium (TAP)
-
Moreno, J. H. Blockage of Gallbladder Tight Junction Cation-Selective Channels by 2,4,6-Triaminopyrimidinium (TAP). J. Gen. Physiol. 1975, 66, 97-115.
-
(1975)
J. Gen. Physiol.
, vol.66
, pp. 97-115
-
-
Moreno, J.H.1
-
23
-
-
0015979129
-
Discrimination of monovalent inorganic cations by "Tight" junctions of gallbladder epithelium
-
Moreno, J. H.; Diamond J. M. Discrimination of Monovalent Inorganic Cations by "Tight" Junctions of Gallbladder Epithelium. J. Membr. Biol. 1974, 15, 277-318.
-
(1974)
J. Membr. Biol.
, vol.15
, pp. 277-318
-
-
Moreno, J.H.1
Diamond, J.M.2
-
24
-
-
0023095484
-
Protamine alters structure and conductance of necturus gallbladder tight junctions without major electrical effects on the apical cell membrane
-
Bentzel, C. J.; Fromm, M.; Palant, C. E.; Hegel, U. Protamine Alters Structure and Conductance of Necturus Gallbladder Tight Junctions Without Major Electrical Effects on the Apical Cell Membrane. J. Membr. Biol. 1987, 95, 9-20.
-
(1987)
J. Membr. Biol.
, vol.95
, pp. 9-20
-
-
Bentzel, C.J.1
Fromm, M.2
Palant, C.E.3
Hegel, U.4
-
25
-
-
0021012702
-
Competitive blocking of epithelial sodium channels by organic cations: The relationship between macroscopic and microscopic inhibition constants
-
Li, J. H.-Y.; Lindemann, B. Competitive Blocking of Epithelial Sodium Channels by Organic Cations: The Relationship between Macroscopic and Microscopic Inhibition Constants. J. Membr. Biol. 1983, 76, 235-251.
-
(1983)
J. Membr. Biol.
, vol.76
, pp. 235-251
-
-
Li, J.H.-Y.1
Lindemann, B.2
-
26
-
-
0030792730
-
Estimation of the relative contribution of the transcellular and paracellular pathways to the transport of passively absorbed drugs in the Caco-2 cell culture model
-
Pade, V.; Stavchansky, S. Estimation of the Relative Contribution of the Transcellular and Paracellular Pathways to the Transport of Passively Absorbed Drugs in the Caco-2 Cell Culture Model. Pharm. Res. 1997, 14, 1210-1215.
-
(1997)
Pharm. Res.
, vol.14
, pp. 1210-1215
-
-
Pade, V.1
Stavchansky, S.2
-
27
-
-
0030931449
-
Paracellular diffusion in Caco-2 cell monolayers: Effect of perturbation on the transport of hydrophilic compounds that vary in charge and size
-
Knipp, G. T.; Ho, N. F. H.; Barsuhn, C. L.; Borchardt, R. T. Paracellular Diffusion in Caco-2 Cell Monolayers: Effect of Perturbation on the Transport of Hydrophilic Compounds that Vary in Charge and Size. J. Pharm. Sci. 1997, 86, 1105-1110.
-
(1997)
J. Pharm. Sci.
, vol.86
, pp. 1105-1110
-
-
Knipp, G.T.1
Ho, N.F.H.2
Barsuhn, C.L.3
Borchardt, R.T.4
-
28
-
-
0028080058
-
Quantitative approaches to delineate paracellular diffusion in cultured epithelial cell monlayers
-
Adison, A.;. Raub, T. J.; Burton, P. S.; Barsuhn, C. L.; Hilgers, A. R.; Audus, K. L.; Ho, N. F. H. Quantitative Approaches to Delineate Paracellular Diffusion in Cultured Epithelial Cell Monlayers. J. Pharm. Sci. 1994, 83, 1529-1536.
-
(1994)
J. Pharm. Sci.
, vol.83
, pp. 1529-1536
-
-
Adison, A.1
Raub, T.J.2
Burton, P.S.3
Barsuhn, C.L.4
Hilgers, A.R.5
Audus, K.L.6
Ho, N.F.H.7
-
29
-
-
85069279167
-
Photoaffinity labeling of the anionic cellular components mediating paracellular transport of cations across Caco-2 cell monolayers
-
Lee, K.; Thakker, D. R. Photoaffinity Labeling of the Anionic Cellular Components Mediating Paracellular Transport of Cations Across Caco-2 Cell Monolayers. PharmSci 1998, 1, S-452.
-
(1998)
PharmSci
, vol.1
-
-
Lee, K.1
Thakker, D.R.2
-
30
-
-
85069280833
-
Potential for drug-drug interactions in the absorption of cationic compounds across intestinal epithelium
-
Lee, K.; Thakker, D. R. Potential for Drug-Drug Interactions in the Absorption of Cationic Compounds Across Intestinal Epithelium. PharmSci 1998, 1, S-453.
-
(1998)
PharmSci
, vol.1
-
-
Lee, K.1
Thakker, D.R.2
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