The Fission Yeast TOR Homolog, tor1+, is Required for the Response to Starvation and other Stresses via a Conserved Serine

Journal of Biological Chemistry

Volumn 276, Issue 10, 2001, Pages 7027-7032

  Weisman, Ronit ^a   Choder, Mordechai ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; GENES; PHOSPHORUS COMPOUNDS; PROTEINS; YEAST;

MITOGENIC SIGNALS;

BIOCHEMISTRY;

ARGININE; FUNGAL DNA; PHOSPHATIDYLINOSITOL KINASE; PROTEIN; PROTEIN TARGET OF RAPAMYCIN; RAPAMYCIN; SERINE; UNCLASSIFIED DRUG; ANTIFUNGAL AGENT; CELL CYCLE PROTEIN; EPITOPE; FK 506 BINDING PROTEIN; FUNGAL PROTEIN; HYBRID PROTEIN; PEPTIDYLPROLYL ISOMERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; SACCHAROMYCES CEREVISIAE PROTEIN; SCHIZOSACCHAROMYCES POMBE PROTEIN; TOR1 PROTEIN, S CEREVISIAE; TOR2 PROTEIN, S CEREVISIAE; TOR2 PROTEIN, S POMBE;

AMINO ACID SUBSTITUTION; ARTICLE; CELL GROWTH; CONTROLLED STUDY; DNA SEQUENCE; FLUORESCENCE ACTIVATED CELL SORTER; FUNGAL GENE; GROWTH CURVE; NONHUMAN; OSMOTIC STRESS; OXIDATIVE STRESS; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; SEQUENCE HOMOLOGY; SEXUAL DEVELOPMENT; STARVATION; STRESS; TOR1 GENE; TOR2 GENE; AMINO ACID SEQUENCE; CHEMISTRY; COLD; DRUG RESISTANCE; FLOW CYTOMETRY; GENETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; OSMOSIS; PHENOTYPE; PHYSIOLOGY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SCHIZOSACCHAROMYCES; SITE DIRECTED MUTAGENESIS; TIME; WESTERN BLOTTING;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE; SACCHAROMYCES POMBE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID SEQUENCE; ANTIBIOTICS, ANTIFUNGAL; ARGININE; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CLONING, MOLECULAR; COLD; CONSERVED SEQUENCE; DRUG RESISTANCE; EPITOPES; FLOW CYTOMETRY; FUNGAL PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; OSMOSIS; OXIDATIVE STRESS; PEPTIDYLPROLYL ISOMERASE; PHENOTYPE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS; SERINE; SIROLIMUS; TACROLIMUS BINDING PROTEIN 1A; TIME FACTORS;

EID: 0035831446     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010446200     Document Type: Article

References (42)

1. Hall, M. N. (1996) Biochem. Soc. Trans. 24, 234-239
2. Cardenas, M. E., Cruz, M. C., Del Poeta, M., Chung, N., Perfect, J. R., and Heitman, J. (1999) Clin. Microbiol. Rev. 12, 583-611
3. Cafferkey, R., Young, P. R., McLaughlin, M. M., Bergsma, D. J., Koltin, Y., Sathe, G. M., Faucette, L., Eng, W. K., Johnson, R. K., and Livi, G. P. (1993) Mol. Cell. Biol. 13, 6012-6023
4. Kunz, J., Henriquez, R., Schneider, U., Deuter-Reinhard, M., Movva, N. R., and Hall, M. N. (1993) Cell 73, 585-596
5. Zheng, X. F., Florentino, D., Chen, J., Crabtree, G. R., and Schreiber, S. L. (1995) Cell 82, 121-130
6. Barbet, N. C., Schneider, U., Helliwell, S. B., Stansfield, I., Tuite, M. F., and Hall, M. N. (1996) Mol. Biol. Cell 7, 25-42
7. Di Como, C. J., and Arndt, K. T. (1996) Genes Dev. 10, 1904-1916
8. Zaragoza, D., Ghavidel, A., Heitman, J., and Schultz, M. C. (1998) Mol. Cell. Biol. 18, 4463-4470
9. Beck, T., and Hall, M. N. (1999) Nature 402, 689-692
10. Schmidt, A., Beck, T., Koller, A., Kunz, J., and Hall, M. N. (1998) EMBO J. 17, 6924-6931
11. Noda, T., and Ohsumi, Y. (1998) J. Biol. Chem. 273, 3963-3966
12. Schmidt, A., Kunz, J., and Hall, M. N. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 13780-13785
13. Schmidt, A., Bickle, M., Beck, T., and Hall, M. N. (1997) Cell 88, 531-542
14. Chiu, M. I., Katz, H., and Berlin, V. (1994) Proc. Natl. Acad. Sci. U. S. A, 91, 12574-12578
15. Chen, J., Zheng, X. F., Brown, E. J., and Schreiber, S. L. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 4947-4951
16. Brown, E. J., Albers, M. W., Shin, T. B., Ichikawa, K., Keith, C. T., Lane, W. S., and Schreiber, S. L. (1994) Nature 369, 756-758
17. Stan, R., McLaughlin, M. M., Cafferkey, R., Johnson, R. K., Rosenberg, M., and Livi, G. P. (1994) J. Biol. Chem. 269, 32027-32030
18. Helliwell, S. B., Wagner, P., Kunz, J., Deuter-Reinhard, M., Henriquez, R., and Hall, M. N. (1994) Mol. Biol. Cell 5, 105-118
19. Lorenz, M. C., and Heitman, J. (1995) J. Biol. Chem. 270, 27531-27537
20. Cruz, M. C., Cavallo, L. M., Gorlach, J. M., Cox, G., Perfect, J. R., Cardenas, M. E., and Heitman, J. (1999) Mol. Cell. Biol. 19, 4101-4112
21. Choi, J., Chen, J., Schreiber, S. L., and Clardy, J. (1996) Science 273, 239-242
22. Brown, E. J., Beal, P. A., Keith, C. T., Chen, J., Shin, T. B., and Schreiber, S. L. (1995) Nature 377, 441-446
23. Brunn, G. J., Hudson, C. C., Sekulic, A., Williams, J. M., Hosoi, H., Houghton, P. J., Lawrence, J. C., Jr., and Abraham, R. T. (1997) Science 277, 99-101
24. Hara, K., Yonezawa, K., Kozlowski, M. T., Sugimoto, T., Andrabi, K., Weng, Q. P., Kasuga, M., Nishimoto, I., and Avruch, J. (1997) J. Biol. Chem. 272, 26457-26463
25. Forsburg, S. L. (1999) Trends Genet 15, 340-344
26. Davey, J. (1998) Yeast 14, 1529-1566
27. Weisman, R., Choder, M., and Koltin, Y. (1997) J Bacteriol 179, 6325-6334
28. Moreno, S., Klar, A., and Nurse, P. (1991) Methods Enzymol. 194, 795-823
29. Prentice, H. L. (1992) Nucleic Acids Res. 20, 621
30. Snaith, H. A., and Forsburg, S. L. (1999) Genetics 152, 839-851
31. Booher, R., and Beach, D. (1986) Mol. Cell. Biol. 6, 3523-3530
32. Gari, E., Piedrafita, L., Aldea, M., and Herrero, E. (1997) Yeast 13, 837-848
33. Ho, S. N., Hunt, H. D., Horton, R. M., Pullen, J. K., and Pease, L. R. (1989) Gene (Amst.) 77, 51-59
34. Forsburg, S. L., and Sherman, D. A. (1997) Gene (Amst.) 191, 191-195
35. Costello, G. F., Rodegers, L., and Beach, D. (1986) Curr. Genet. 11, 119-125
36. Moreno, S., and Nurse, P. (1994) Nature 367, 236-242
37. Takeda, T., Toda, T., Kominami, K., Kohnosu, A., Yanagida, M., and Jones, N. (1995) EMBO J. 14, 6193-6208
38. Shiozaki, K., and Russell, P. (1996) Genes Dev. 10, 2276-2288
39. Wilkinson, M. G., Samuels, M., Takeda, T., Toone, W. M., Shieh, J. C., Toda, T., Millar, J. B., and Jones, N. (1996) Genes Dev. 10, 2289-2301
40. Cutler, N. S., Heitman, J., and Cardenas, M. E. (1999) Mol. Cell. Endocrinol. 155, 135-142
41. Zheng, X. F., and Schreiber, S. L. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 3070-3075
42. Hardwick, J. S., Kuruvilla, F. G., Tong, J. K., Shamji, A. F., and Schreiber, S. L. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 14866-14870