-
1
-
-
0028284167
-
Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a μ-, δ- or κ-opioid receptor type
-
Bunzow JR, Saez C, Mortrud M, Bouvier C, Williams JT, Low M, Grandy DK: Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a μ-, δ- or κ-opioid receptor type. FEBS Lett 1994;347:284-288.
-
(1994)
FEBS Lett
, vol.347
, pp. 284-288
-
-
Bunzow, J.R.1
Saez, C.2
Mortrud, M.3
Bouvier, C.4
Williams, J.T.5
Low, M.6
Grandy, D.K.7
-
2
-
-
0028308020
-
Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family
-
Chen Y, Fan Y, Liu J, Mestek A, Tian M, Kozak CA, Yu L: Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family. FEBS Lett 1994;347:279-283.
-
(1994)
FEBS Lett
, vol.347
, pp. 279-283
-
-
Chen, Y.1
Fan, Y.2
Liu, J.3
Mestek, A.4
Tian, M.5
Kozak, C.A.6
Yu, L.7
-
3
-
-
0028279934
-
cDNA cloning and regional distribution of a novel member of the opioid receptor family
-
Fukuda K, Kato S, Mori K, Nishi M, Takeshima H, Iwabe N, Miyata T, Houtani T, Sugimoto T: cDNA cloning and regional distribution of a novel member of the opioid receptor family. FEBS Lett 1994;343:42-46.
-
(1994)
FEBS Lett
, vol.343
, pp. 42-46
-
-
Fukuda, K.1
Kato, S.2
Mori, K.3
Nishi, M.4
Takeshima, H.5
Iwabe, N.6
Miyata, T.7
Houtani, T.8
Sugimoto, T.9
-
4
-
-
0028226886
-
1, a novel member of the opioid receptor family: Cloning, functional expression and localization
-
1, a novel member of the opioid receptor family: Cloning, functional expression and localization. FEBS Lett 1994;341:33-38.
-
(1994)
FEBS Lett
, vol.341
, pp. 33-38
-
-
Mollereau, C.1
Parmentier, M.2
Mailleux, P.3
Butour, J.L.4
Moisand, C.5
Chalon, P.6
Caput, D.7
Vassart, G.8
Meunier, J.C.9
-
5
-
-
0028225109
-
cDNA cloning of an orphan opiate receptor gene family member and its splice variant
-
Wang JB, Johnson PS, Imai Y, Persico AM, Ozenberger BA, Eppler CM, Uhl GR: cDNA cloning of an orphan opiate receptor gene family member and its splice variant. FEBS Lett 1994;348:75-79.
-
(1994)
FEBS Lett
, vol.348
, pp. 75-79
-
-
Wang, J.B.1
Johnson, P.S.2
Imai, Y.3
Persico, A.M.4
Ozenberger, B.A.5
Eppler, C.M.6
Uhl, G.R.7
-
6
-
-
0028072363
-
Isolation of a novel cDNA encoding a putative membrane receptor with high homology to the cloned μ-, δ-, and κ-opioid receptors
-
Wick MJ, Minnerath SR, Lin X, Elde R, Law PY, Loh HH: Isolation of a novel cDNA encoding a putative membrane receptor with high homology to the cloned μ-, δ-, and κ-opioid receptors. Brain Res Mol Brain Res 1994;27:37-44.
-
(1994)
Brain Res Mol Brain Res
, vol.27
, pp. 37-44
-
-
Wick, M.J.1
Minnerath, S.R.2
Lin, X.3
Elde, R.4
Law, P.Y.5
Loh, H.H.6
-
7
-
-
0029076795
-
Functional role and sequence analysis of a lymphocyte orphan opioid receptor
-
Halford WP, Gebhardt BM, Carr DJ: Functional role and sequence analysis of a lymphocyte orphan opioid receptor. J Neuroimmunol 1995;59:91-101.
-
(1995)
J Neuroimmunol
, vol.59
, pp. 91-101
-
-
Halford, W.P.1
Gebhardt, B.M.2
Carr, D.J.3
-
8
-
-
0028894449
-
Molecular cloning of a novel G protein-coupled receptor related to the opiate receptor family
-
Lachowicz JE, Shen Y, Monsma FJ Jr, Sibley DR: Molecular cloning of a novel G protein-coupled receptor related to the opiate receptor family. J Neurochem 1995;64:34-40.
-
(1995)
J Neurochem
, vol.64
, pp. 34-40
-
-
Lachowicz, J.E.1
Shen, Y.2
Monsma Jr., F.J.3
Sibley, D.R.4
-
9
-
-
0029065852
-
Cloning and functional characterization through functional mapping of a κ3-related opioid receptor
-
Pan YX, Cheng J, Xu J, Rossi G, Jacobson E, Ryan-Moro J, Brooks AI, Dean GE, Standifer KM, Pasternak GW: Cloning and functional characterization through functional mapping of a κ3-related opioid receptor. Mol Pharmacol 1995;47:1180-1188.
-
(1995)
Mol Pharmacol
, vol.47
, pp. 1180-1188
-
-
Pan, Y.X.1
Cheng, J.2
Xu, J.3
Rossi, G.4
Jacobson, E.5
Ryan-Moro, J.6
Brooks, A.I.7
Dean, G.E.8
Standifer, K.M.9
Pasternak, G.W.10
-
10
-
-
0030472350
-
International Union of Pharmacology. XII. Classification of opioid receptors
-
Dhawan BN, Cesselin F, Raghubir R, Reisine T, Bradley PB, Portoghese PS, Hamon M: International Union of Pharmacology. XII. Classification of opioid receptors. Pharmacol Rev 1996;48:567-592.
-
(1996)
Pharmacol Rev
, vol.48
, pp. 567-592
-
-
Dhawan, B.N.1
Cesselin, F.2
Raghubir, R.3
Reisine, T.4
Bradley, P.B.5
Portoghese, P.S.6
Hamon, M.7
-
11
-
-
0003274798
-
The new approach to opioid receptors
-
Hamon M: The new approach to opioid receptors. Naunyn Schmiedebergs Arch Pharmacol 1998;358(suppl 2):5A53.
-
(1998)
Naunyn Schmiedebergs Arch Pharmacol
, vol.358
, Issue.2 SUPPL.
-
-
Hamon, M.1
-
12
-
-
0029166509
-
1 receptor
-
1 receptor. Nature 1995;377:532-535.
-
(1995)
Nature
, vol.377
, pp. 532-535
-
-
Meunier, J.C.1
Mollereau, C.2
Toll, L.3
Suaudeau, C.4
Moisand, C.5
Alvinerie, P.6
Butour, J.L.7
Guillemot, J.C.8
Ferrara, P.9
Monsarrat, B.10
-
13
-
-
0028971215
-
Orphanin FQ: A neuropeptide that activates an opioid-like G protein-coupled receptor
-
Reinscheid RK, Nothacker HP, Bourson A, Ardati A, Henningsen RA, Bunzow JR, Grandy DK, Langen H, Monsma FJ, Civelli O: Orphanin FQ: A neuropeptide that activates an opioid-like G protein-coupled receptor. Science 1995;270:792-794.
-
(1995)
Science
, vol.270
, pp. 792-794
-
-
Reinscheid, R.K.1
Nothacker, H.P.2
Bourson, A.3
Ardati, A.4
Henningsen, R.A.5
Bunzow, J.R.6
Grandy, D.K.7
Langen, H.8
Monsma, F.J.9
Civelli, O.10
-
14
-
-
0034850298
-
The molecular and behavioural pharmacology of the orphanin FQ/nociceptin peptide and receptor family
-
Mogil JS, Pasternak GW: The molecular and behavioural pharmacology of the orphanin FQ/nociceptin peptide and receptor family. Pharmacol Rev 2001;53:381-415.
-
(2001)
Pharmacol Rev
, vol.53
, pp. 381-415
-
-
Mogil, J.S.1
Pasternak, G.W.2
-
16
-
-
0033821691
-
The orphanin FQ/nociceptin gene: Structure, tissue distribution of expression and functional implications obtained from knockout mice
-
Reinscheid RK, Nothacker H, Civelli O: The orphanin FQ/nociceptin gene: Structure, tissue distribution of expression and functional implications obtained from knockout mice. Peptides 2000;21:901-906.
-
(2000)
Peptides
, vol.21
, pp. 901-906
-
-
Reinscheid, R.K.1
Nothacker, H.2
Civelli, O.3
-
17
-
-
0345158331
-
Specific receptor for the opioid dynorphin: Structure-activity relationships
-
Chavkin C, Goldstein A: Specific receptor for the opioid dynorphin: Structure-activity relationships. Proc Natl Acad Sci USA 1981;78:6543-6547.
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 6543-6547
-
-
Chavkin, C.1
Goldstein, A.2
-
18
-
-
0024334804
-
Recent developments in the design of receptor specific opioid peptides
-
Hruby VJ, Gehrig CA: Recent developments in the design of receptor specific opioid peptides. Med Res Rev 1989;9:343-401.
-
(1989)
Med Res Rev
, vol.9
, pp. 343-401
-
-
Hruby, V.J.1
Gehrig, C.A.2
-
19
-
-
0342726574
-
Structure-activity relationship studies on the novel neuropeptide orphanin FQ
-
Reinscheid RK, Ardati A, Monsma FJ Jr, Civelli O: Structure-activity relationship studies on the novel neuropeptide orphanin FQ. J Biol Chem 1996;271:14163-14168.
-
(1996)
J Biol Chem
, vol.271
, pp. 14163-14168
-
-
Reinscheid, R.K.1
Ardati, A.2
Monsma Jr., F.J.3
Civelli, O.4
-
20
-
-
0031892150
-
Structures that delineate orphanin FQ and dynorphin A pharmacological selectivities
-
Reinscheid RK, Higelin J, Henningsen RA, Monsma FJ Jr, Civelli O: Structures that delineate orphanin FQ and dynorphin A pharmacological selectivities. J Biol Chem 1998;273:1490-1495.
-
(1998)
J Biol Chem
, vol.273
, pp. 1490-1495
-
-
Reinscheid, R.K.1
Higelin, J.2
Henningsen, R.A.3
Monsma Jr., F.J.4
Civelli, O.5
-
21
-
-
10544231050
-
Moving from the orphanin FQ receptor to an opioid receptor using four point mutations
-
Meng F, Taylor LP, Hoversten MT, Ueda Y, Ardati A, Reinscheid RK, Monsma FJ, Watson SJ, Civelli O, Akil H: Moving from the orphanin FQ receptor to an opioid receptor using four point mutations. J Biol Chem 1996;271:32016-32020.
-
(1996)
J Biol Chem
, vol.271
, pp. 32016-32020
-
-
Meng, F.1
Taylor, L.P.2
Hoversten, M.T.3
Ueda, Y.4
Ardati, A.5
Reinscheid, R.K.6
Monsma, F.J.7
Watson, S.J.8
Civelli, O.9
Akil, H.10
-
22
-
-
0033023897
-
Distinct mechanisms of activation of the opioid receptor-like 1 and κ-opioid receptors by nociceptin and dynorphin A
-
Mollereau C, Moulédous L, Lapalu S, Cambois G, Moisand C, Butour JL, Meunier JC: Distinct mechanisms of activation of the opioid receptor-like 1 and κ-opioid receptors by nociceptin and dynorphin A. Mol Pharmacol 1999;55:324-331.
-
(1999)
Mol Pharmacol
, vol.55
, pp. 324-331
-
-
Mollereau, C.1
Moulédous, L.2
Lapalu, S.3
Cambois, G.4
Moisand, C.5
Butour, J.L.6
Meunier, J.C.7
-
25
-
-
0029156770
-
A computer modeling postulated mechanism for angiotensin II receptor activation
-
Joseph MP, Maigret B, Bonnafus JC, Marie J, Scherega HA: A computer modeling postulated mechanism for angiotensin II receptor activation. J Protein Chem 1997;14:381-398.
-
(1997)
J Protein Chem
, vol.14
, pp. 381-398
-
-
Joseph, M.P.1
Maigret, B.2
Bonnafus, J.C.3
Marie, J.4
Scherega, H.A.5
-
27
-
-
0032923919
-
2 receptor induced by mutations in transmembrane helices III and VI
-
2 receptor induced by mutations in transmembrane helices III and VI. Mol Pharmacol 1999;55:92-101.
-
(1999)
Mol Pharmacol
, vol.55
, pp. 92-101
-
-
Marie, J.1
Koch, C.2
Pruneau, D.3
Paquet, J.L.4
Groblewski, T.5
Larguier, R.6
Lombard, C.7
Deslauriers, B.8
Maigret, B.9
Bonnafous, J.C.10
-
28
-
-
0343150924
-
Orphanin FQ: Receptor binding and analog structure-activity relationships in rat brain
-
Dooley CT, Houghten RA: Orphanin FQ: Receptor binding and analog structure-activity relationships in rat brain. Life Sci 1996;59:PL23-PL29.
-
(1996)
Life Sci
, vol.59
-
-
Dooley, C.T.1
Houghten, R.A.2
-
30
-
-
0030597209
-
Dissociation of affinity and efficacy in KOR-3 chimeras
-
Pan YX, Xu J, Ryan-Moro J, Mathis JP, Hom JSH, Mei JF, Pasternak GW: Dissociation of affinity and efficacy in KOR-3 chimeras. FEBS Lett 1996;395:207-210.
-
(1996)
FEBS Lett
, vol.395
, pp. 207-210
-
-
Pan, Y.X.1
Xu, J.2
Ryan-Moro, J.3
Mathis, J.P.4
Hom, J.S.H.5
Mei, J.F.6
Pasternak, G.W.7
-
31
-
-
0031566183
-
Biochemical evidence for orphanin FQ/nociceptin receptor heterogeniety in mouse brain
-
Mathis JP, Ryan-Moro J, Chang A, Hom JSH, Scheinberg DA, Pasternak GW: Biochemical evidence for orphanin FQ/nociceptin receptor heterogeniety in mouse brain. Biochem Biophys Res Commun 1997;230:462-465.
-
(1997)
Biochem Biophys Res Commun
, vol.230
, pp. 462-465
-
-
Mathis, J.P.1
Ryan-Moro, J.2
Chang, A.3
Hom, J.S.H.4
Scheinberg, D.A.5
Pasternak, G.W.6
-
32
-
-
0033821749
-
Orphanin FQ/nociceptin receptor binding studies
-
Dooley CT, Houghten RA: Orphanin FQ/nociceptin receptor binding studies. Peptides 2000;21:949-960.
-
(2000)
Peptides
, vol.21
, pp. 949-960
-
-
Dooley, C.T.1
Houghten, R.A.2
-
33
-
-
0030734901
-
Relationship between binding affinity and functional activity of nociceptin/orphanin FQ
-
Adapa ID, Toll L: Relationship between binding affinity and functional activity of nociceptin/orphanin FQ. Neuropeptides 1997;31:403-408.
-
(1997)
Neuropeptides
, vol.31
, pp. 403-408
-
-
Adapa, I.D.1
Toll, L.2
-
36
-
-
0033816845
-
Integrity of orphanin FQ/nociceptin: Implications for establishing a reliable binding assay
-
Quigley DI, Arttamangkul S, Allen RG, Grandy DK: Integrity of orphanin FQ/nociceptin: Implications for establishing a reliable binding assay. Peptides 2000;21:1111-1118.
-
(2000)
Peptides
, vol.21
, pp. 1111-1118
-
-
Quigley, D.I.1
Arttamangkul, S.2
Allen, R.G.3
Grandy, D.K.4
-
37
-
-
0030344645
-
Nociceptin in vitro biotransformation in human blood
-
Yu J, Chait BT, Toll L, Kreek MJ: Nociceptin in vitro biotransformation in human blood. Peptides 1996;17:873-876.
-
(1996)
Peptides
, vol.17
, pp. 873-876
-
-
Yu, J.1
Chait, B.T.2
Toll, L.3
Kreek, M.J.4
-
39
-
-
0032801518
-
Metabolic fate of nociceptin/orphanin FQ in the rat spinal cord and biological activity of its released fragment
-
Suder P, Kotlinska J, Smoluch MT, Sallberg M, Silberring J: Metabolic fate of nociceptin/orphanin FQ in the rat spinal cord and biological activity of its released fragment. Peptides 1999;20:239-247.
-
(1999)
Peptides
, vol.20
, pp. 239-247
-
-
Suder, P.1
Kotlinska, J.2
Smoluch, M.T.3
Sallberg, M.4
Silberring, J.5
-
40
-
-
0031006367
-
Address and message sequences for the nociceptin receptor: A structure-activity study of nociceptin-(1-13)-peptide amide
-
Guerrini R, Calo G, Rizzi A, Bianchi C, Lazarus LH, Salvadori S, Temussi PA, Regoli D: Address and message sequences for the nociceptin receptor: A structure-activity study of nociceptin-(1-13)-peptide amide. J Med Chem 1997;40:1789-1793.
-
(1997)
J Med Chem
, vol.40
, pp. 1789-1793
-
-
Guerrini, R.1
Calo, G.2
Rizzi, A.3
Bianchi, C.4
Lazarus, L.H.5
Salvadori, S.6
Temussi, P.A.7
Regoli, D.8
-
41
-
-
0031792201
-
Nociceptin receptor binding in mouse forebrain membranes: Thermodynamic characteristics and structure-activity relationships
-
Varani K, Calo G, Rizzi A, Merighi S, Toth G, Guerrini R, Salvadori S, Borea PA, Regoli D: Nociceptin receptor binding in mouse forebrain membranes: Thermodynamic characteristics and structure-activity relationships. Br J Pharmacol 1998;125:1485-1490.
-
(1998)
Br J Pharmacol
, vol.125
, pp. 1485-1490
-
-
Varani, K.1
Calo, G.2
Rizzi, A.3
Merighi, S.4
Toth, G.5
Guerrini, R.6
Salvadori, S.7
Borea, P.A.8
Regoli, D.9
-
42
-
-
0032588075
-
2 in rat brain, rat vas deferens and CHO cells expressing recombinant human nociceptin receptors
-
2 in rat brain, rat vas deferens and CHO cells expressing recombinant human nociceptin receptors. Br J Pharmacol 1999;127:123-130.
-
(1999)
Br J Pharmacol
, vol.127
, pp. 123-130
-
-
Okawa, H.1
Nicol, B.2
Bigoni, R.3
Hirst, R.A.4
Calo, G.5
Guerrini, R.6
Rowbotham, D.J.7
Smart, D.8
McKnight, A.T.9
Lambert, D.G.10
-
43
-
-
0034101011
-
Pharmacology of nociceptin and its receptor: A novel therapeutic target
-
Calo G, Guerrini R, Rizzi A, Salvadori S, Regoli D: Pharmacology of nociceptin and its receptor: A novel therapeutic target. Br J Pharmacol 2000;129:1261-1283.
-
(2000)
Br J Pharmacol
, vol.129
, pp. 1261-1283
-
-
Calo, G.1
Guerrini, R.2
Rizzi, A.3
Salvadori, S.4
Regoli, D.5
-
44
-
-
0034687553
-
Highly potent nociceptin analog containing the Arg-Lys triple repeat
-
Okada K, Sujaku T, Chuman Y, Nakashima R, Nose T, Costa T, Yamada Y, Yokoyama M, Nagahisa A, Shimohigashi Y: Highly potent nociceptin analog containing the Arg-Lys triple repeat. Biochem Biophys Res Commun 2000;278:493-498.
-
(2000)
Biochem Biophys Res Commun
, vol.278
, pp. 493-498
-
-
Okada, K.1
Sujaku, T.2
Chuman, Y.3
Nakashima, R.4
Nose, T.5
Costa, T.6
Yamada, Y.7
Yokoyama, M.8
Nagahisa, A.9
Shimohigashi, Y.10
-
45
-
-
0036139497
-
15]nociceptin, a highly potent agonist of the nociceptin/orphanin FQ receptor: In vitro and in vivo studies
-
15]nociceptin, a highly potent agonist of the nociceptin/orphanin FQ receptor: In vitro and in vivo studies. J Pharmacol Exp Ther 2002;300:57-63.
-
(2002)
J Pharmacol Exp Ther
, vol.300
, pp. 57-63
-
-
Rizzi, D.1
Rizzi, A.2
Bigoni, R.3
Camarda, V.4
Marzola, G.5
Guerrini, R.6
De Risi, C.7
Regoli, D.8
Calo, G.9
-
46
-
-
0035829420
-
2: Identification of highly potent agonists of the nociceptin/orphanin FQ receptor
-
2: Identification of highly potent agonists of the nociceptin/orphanin FQ receptor. J Med Chem 2001;44:3956-3964.
-
(2001)
J Med Chem
, vol.44
, pp. 3956-3964
-
-
Guerrini, R.1
Calo, G.2
Bigoni, R.3
Rizzi, D.4
Rizzi, A.5
Zucchini, M.6
Varani, K.7
Hashiba, E.8
Lambert, D.G.9
Toth, G.10
Borea, P.A.11
Salvadori, S.12
Regoli, D.13
-
50
-
-
0031694279
-
Pharmacological characterization of the nociceptin receptor mediating hyperalgesia in the mouse tail withdrawal assay
-
Calo G, Rizzi A, Marzola G, Guerrini R, Salvadori S, Beani L, Regoli D, Bianchi C: Pharmacological characterization of the nociceptin receptor mediating hyperalgesia in the mouse tail withdrawal assay. Br J Pharmacol 1998;125:373-378.
-
(1998)
Br J Pharmacol
, vol.125
, pp. 373-378
-
-
Calo, G.1
Rizzi, A.2
Marzola, G.3
Guerrini, R.4
Salvadori, S.5
Beani, L.6
Regoli, D.7
Bianchi, C.8
-
51
-
-
17144435547
-
Further studies on nociceptin-related peptides: Discovery of a new chemical template with antagonist activity on the nociceptin receptor
-
Guerrini R, Calo G, Bigoni R, Rizzi A, Varani K, Toth G, Gessi S, Hashiba E, Hashimoto Y, Lambert DG, Borea PA, Tomatis R, Salvadori S, Regoli D: Further studies on nociceptin-related peptides: Discovery of a new chemical template with antagonist activity on the nociceptin receptor. J Med Chem 2000;43:2805-2813.
-
(2000)
J Med Chem
, vol.43
, pp. 2805-2813
-
-
Guerrini, R.1
Calo, G.2
Bigoni, R.3
Rizzi, A.4
Varani, K.5
Toth, G.6
Gessi, S.7
Hashiba, E.8
Hashimoto, Y.9
Lambert, D.G.10
Borea, P.A.11
Tomatis, R.12
Salvadori, S.13
Regoli, D.14
-
52
-
-
0034101842
-
2, a new selective nociceptin receptor antagonist
-
2, a new selective nociceptin receptor antagonist. Br J Pharmacol 2000;129:1183-1193.
-
(2000)
Br J Pharmacol
, vol.129
, pp. 1183-1193
-
-
Calo, G.1
Guerrini, R.2
Bigoni, R.3
Rizzi, A.4
Marzola, G.5
Okawa, H.6
Bianchi, C.7
Lambert, D.G.8
Salvadori, S.9
Regoli, D.10
-
56
-
-
0036008783
-
2 antagonizes nociceptin-induced hypotension, bradycardia, and hindquarters vasodilation in the anesthetized rat
-
2 antagonizes nociceptin-induced hypotension, bradycardia, and hindquarters vasodilation in the anesthetized rat. Can J Physiol Pharmacol 2002;80:31-35.
-
(2002)
Can J Physiol Pharmacol
, vol.80
, pp. 31-35
-
-
Chen, Y.1
Chang, M.2
Wang, Z.Z.3
Chen, L.X.4
Yang, Q.5
Qi, Y.M.6
Wang, R.7
-
57
-
-
0035807758
-
2 in mice
-
2 in mice. Neurosci Lett 2001;316:25-28.
-
(2001)
Neurosci Lett
, vol.316
, pp. 25-28
-
-
Di Giannuario, A.1
Rizzi, A.2
Pieretti, S.3
Guerrini, R.4
Bertorelli, R.5
Salvadori, S.6
Regoli, D.7
Calo, G.8
-
58
-
-
0033600840
-
1 receptors identified from a conformationally constrained peptide combinatorial library
-
1 receptors identified from a conformationally constrained peptide combinatorial library. J Biol Chem 1999;274:27513-27522.
-
(1999)
J Biol Chem
, vol.274
, pp. 27513-27522
-
-
Becker, J.A.1
Wallace, A.2
Garzon, A.3
Ingallinella, P.4
Bianchi, E.5
Cortese, R.6
Simonin, F.7
Kieffer, B.L.8
Pessi, A.9
-
59
-
-
0033811727
-
Nociceptin/orphanin FQ receptor ligands
-
Calo G, Bigoni R, Rizzi A, Guerrini R, Salvadori S, Regoli D: Nociceptin/orphanin FQ receptor ligands. Peptides 2000;21:935-947.
-
(2000)
Peptides
, vol.21
, pp. 935-947
-
-
Calo, G.1
Bigoni, R.2
Rizzi, A.3
Guerrini, R.4
Salvadori, S.5
Regoli, D.6
-
60
-
-
0033575662
-
8-Acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as orphanin FQ receptor agonists
-
Wichmann J, Adam G, Rover S, Cesura AM, Dautzenberg FM, Jenck F: 8-Acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as orphanin FQ receptor agonists. Bioorg Med Chem Lett 1999;9:2343-2348.
-
(1999)
Bioorg Med Chem Lett
, vol.9
, pp. 2343-2348
-
-
Wichmann, J.1
Adam, G.2
Rover, S.3
Cesura, A.M.4
Dautzenberg, F.M.5
Jenck, F.6
-
61
-
-
0342749308
-
1 (orphanin FQ/nociceptin) receptor
-
1 (orphanin FQ/nociceptin) receptor. J Med Chem 2000;43:1329-1338.
-
(2000)
J Med Chem
, vol.43
, pp. 1329-1338
-
-
Rover, S.1
Adam, G.2
Cesura, A.M.3
Galley, G.4
Jenck, F.5
Monsma Jr., F.J.6
Wichmann, J.7
Dautzenberg, F.M.8
-
62
-
-
0342313481
-
ORL1 receptor ligands: Structure-activity relationships of 8-cycloalkyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-ones
-
Rover S, Wichmann J, Jenck F, Adam G, Cesura AM: ORL1 receptor ligands: Structure-activity relationships of 8-cycloalkyl-1-phenyl-1,3,8-triaza-spiro[4. 5]decan-4-ones. Bioorg Med Chem Lett 2000;10:831-834.
-
(2000)
Bioorg Med Chem Lett
, vol.10
, pp. 831-834
-
-
Rover, S.1
Wichmann, J.2
Jenck, F.3
Adam, G.4
Cesura, A.M.5
-
63
-
-
0034712756
-
1: Anxiolytic profile in the rat
-
1: Anxiolytic profile in the rat. Proc Natl Acad Sci USA 2000;97:4938-4943.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 4938-4943
-
-
Jenck, F.1
Wichmann, J.2
Dautzenberg, F.M.3
Moreau, J.L.4
Ouagazzal, A.M.5
Martin, J.R.6
Lundstrom, K.7
Cesura, A.M.8
Poli, S.M.9
Roever, S.10
Kolczewski, S.11
Adam, G.12
Kilpatrick, G.13
-
64
-
-
0033818484
-
Synthesis of (1S,3aS)-8-(2,3,3a,4,5,6-hexahydro-1H-phenalen-1-yl)-1- phenyl-1,3,8-triaza-spiro[4.5]decan-4-one, a potent and selective orphanin FQ (OFQ) receptor agonist with anxiolytic-like properties
-
Wichmann J, Adam G, Rover S, Hennig M, Scalone M, Cesura AM, Dautzenberg FM, Jenck F: Synthesis of (1S,3aS)-8-(2,3,3a,4,5,6-hexahydro-1H-phenalen-1-yl)- 1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one, a potent and selective orphanin FQ (OFQ) receptor agonist with anxiolytic-like properties. Eur J Med Chem 2000;35:839-851.
-
(2000)
Eur J Med Chem
, vol.35
, pp. 839-851
-
-
Wichmann, J.1
Adam, G.2
Rover, S.3
Hennig, M.4
Scalone, M.5
Cesura, A.M.6
Dautzenberg, F.M.7
Jenck, F.8
-
65
-
-
0034920548
-
1 receptor in vitro and lack of tolerance in vivo
-
1 receptor in vitro and lack of tolerance in vivo. J Pharmacol Exp Ther 2001;298:812-819.
-
(2001)
J Pharmacol Exp Ther
, vol.298
, pp. 812-819
-
-
Dautzenberg, F.M.1
Wichmann, J.2
Higelin, J.3
Py-Lang, G.4
Kratzeisen, C.5
Malherbe, P.6
Kilpatrick, G.J.7
Jenck, F.8
-
66
-
-
0034972792
-
1 receptor agonist, Ro64-6198, on rodent neurological function
-
1 receptor agonist, Ro64-6198, on rodent neurological function. Neuropharmacology 2001;41:97-107.
-
(2001)
Neuropharmacology
, vol.41
, pp. 97-107
-
-
Higgins, G.A.1
Grottick, A.J.2
Ballard, T.M.3
Richards, J.G.4
Messer, J.5
Takeshima, H.6
Pauly-Evers, M.7
Jenck, F.8
Adam, G.9
Wichmann, J.10
-
67
-
-
0035002663
-
Effects of Ro 64-6198 in nociceptin/orphanin FQ-sensitive isolated tissues
-
Rizzi D, Bigoni R, Rizzi A, Jenck F, Wichmann J, Guerrini R, Regoli D, Calo G: Effects of Ro 64-6198 in nociceptin/orphanin FQ-sensitive isolated tissues. Naunyn Schmiedebergs Arch Pharmacol 2001;363:551-555.
-
(2001)
Naunyn Schmiedebergs Arch Pharmacol
, vol.363
, pp. 551-555
-
-
Rizzi, D.1
Bigoni, R.2
Rizzi, A.3
Jenck, F.4
Wichmann, J.5
Guerrini, R.6
Regoli, D.7
Calo, G.8
-
68
-
-
0033576679
-
1) antagonist: 1-[(3R,4R)-1-cyclooctylmethyl-3- hydroxy-methyl-4-piperidyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one (J-113397)
-
1) antagonist: 1-[(3R,4R)-1-cyclooctylmethyl-3- hydroxy-methyl-4-piperidyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one (J-113397). J Med Chem 1999;42:5061-5063.
-
(1999)
J Med Chem
, vol.42
, pp. 5061-5063
-
-
Kawamoto, H.1
Ozaki, S.2
Itoh, Y.3
Miyaji, M.4
Arai, S.5
Nakashima, H.6
Kato, T.7
Ohta, H.8
Iwasawa, Y.9
-
69
-
-
0034683206
-
1 receptor antagonist
-
1 receptor antagonist. Eur J Pharmacol 2000;402:45-53.
-
(2000)
Eur J Pharmacol
, vol.402
, pp. 45-53
-
-
Ozaki, S.1
Kawamoto, H.2
Itoh, Y.3
Miyaji, M.4
Azuma, T.5
Ichikawa, D.6
Nambu, H.7
Iguchi, T.8
Iwasawa, Y.9
Ohta, H.10
-
70
-
-
0036177933
-
1 receptor-mediated inhibition of noradrenaline release in human and rat neocortical slices
-
1 receptor-mediated inhibition of noradrenaline release in human and rat neocortical slices. Br J Pharmacol 2002;135:800-806.
-
(2002)
Br J Pharmacol
, vol.135
, pp. 800-806
-
-
Rominger, A.1
Forster, S.2
Zentner, J.3
Dooley, D.J.4
McKnight, A.T.5
Feuerstein, T.J.6
Jackisch, R.7
Vlaskovska, M.8
-
71
-
-
0036152650
-
Pharmacological properties of nociceptin/orphanin FQ-induced stimulation and inhibition of cyclic AMP formation in distinct layers of rat olfactory bulb
-
Olianas MC, Onali P: Pharmacological properties of nociceptin/orphanin FQ-induced stimulation and inhibition of cyclic AMP formation in distinct layers of rat olfactory bulb. Br J Pharmacol 2002;135:233-238.
-
(2002)
Br J Pharmacol
, vol.135
, pp. 233-238
-
-
Olianas, M.C.1
Onali, P.2
-
72
-
-
0035425765
-
Actions of nociceptin/orphanin FQ and other prepronociceptin products on rat rostral ventromedial medulla neurons in vitro
-
Vaughan CW, Connor M, Jennings EA, Marinelli S, Allen RG, Christie MJ: Actions of nociceptin/orphanin FQ and other prepronociceptin products on rat rostral ventromedial medulla neurons in vitro. J Physiol (Lond) 2001;534:849-859.
-
(2001)
J Physiol (Lond)
, vol.534
, pp. 849-859
-
-
Vaughan, C.W.1
Connor, M.2
Jennings, E.A.3
Marinelli, S.4
Allen, R.G.5
Christie, M.J.6
-
73
-
-
0035804779
-
Bi-directional modulation of 5-hydroxytryptamine-induced plasma extravasation in the rat knee joint by nociceptin
-
Grond S, Gabriel A, Pietruck C, Yu LC, Xie GX, Pierce Palmer P: Bi-directional modulation of 5-hydroxytryptamine-induced plasma extravasation in the rat knee joint by nociceptin. Neuroscience 2001;103:1085-1092.
-
(2001)
Neuroscience
, vol.103
, pp. 1085-1092
-
-
Grond, S.1
Gabriel, A.2
Pietruck, C.3
Yu, L.C.4
Xie, G.X.5
Pierce Palmer, P.6
-
75
-
-
0032575999
-
1 and μ-opioid receptor antisera label different fibers in areas involved in pain processing
-
1 and μ-opioid receptor antisera label different fibers in areas involved in pain processing. J Comp Neurol 1998;399:373-383.
-
(1998)
J Comp Neurol
, vol.399
, pp. 373-383
-
-
Monteillet-Agius, G.1
Fein, J.2
Anton, B.3
Evans, C.J.4
-
76
-
-
0033698211
-
A cellular mechanism for the bidirectional pain-modulating actions of orphanin FQ/nociceptin
-
Pan Z, Hirakawa N, Fields HL: A cellular mechanism for the bidirectional pain-modulating actions of orphanin FQ/nociceptin. Neuron 2000;26:515-522.
-
(2000)
Neuron
, vol.26
, pp. 515-522
-
-
Pan, Z.1
Hirakawa, N.2
Fields, H.L.3
-
77
-
-
0033811728
-
Nociceptin/orphanin FQ in spinal nociceptive mechanisms under normal and pathological conditions
-
Xu X, Grass S, Hao J, Xu IS, Wiesenfeld-Hallin Z: Nociceptin/orphanin FQ in spinal nociceptive mechanisms under normal and pathological conditions. Peptides 2000;21:1031-1036.
-
(2000)
Peptides
, vol.21
, pp. 1031-1036
-
-
Xu, X.1
Grass, S.2
Hao, J.3
Xu, I.S.4
Wiesenfeld-Hallin, Z.5
-
78
-
-
0035653648
-
Central and peripheral roles of prostaglandins in pain and their interactions with novel neuropeptides nociceptin and nocistatin
-
Ito S, Okuda-Ashitaka E, Minami T: Central and peripheral roles of prostaglandins in pain and their interactions with novel neuropeptides nociceptin and nocistatin. Neurosci Res 2001;41:299-332.
-
(2001)
Neurosci Res
, vol.41
, pp. 299-332
-
-
Ito, S.1
Okuda-Ashitaka, E.2
Minami, T.3
-
81
-
-
0030787722
-
Endogenous opioid receptor-like receptor in human neuroblastoma SK-N-SH cells: Activation of inhibitory G protein and homologous desensitization
-
Cheng ZJ, Fan GH, Zhao J, Zhang Z, Wu YL, Jiang LZ, Zhu Y, Pei G, Ma L: Endogenous opioid receptor-like receptor in human neuroblastoma SK-N-SH cells: Activation of inhibitory G protein and homologous desensitization. Neuroreport 1997;8:1913-1918.
-
(1997)
Neuroreport
, vol.8
, pp. 1913-1918
-
-
Cheng, Z.J.1
Fan, G.H.2
Zhao, J.3
Zhang, Z.4
Wu, Y.L.5
Jiang, L.Z.6
Zhu, Y.7
Pei, G.8
Ma, L.9
-
83
-
-
0033615104
-
1 receptor induces supersensitization of adenylyl cyclase
-
1 receptor induces supersensitization of adenylyl cyclase. Neuroreport 1999;10:2901-2905.
-
(1999)
Neuroreport
, vol.10
, pp. 2901-2905
-
-
Chan, R.Y.1
Wong, Y.H.2
-
85
-
-
0028822469
-
Activation of type II adenylyl cyclase by the cloned μ-opioid receptor: Coupling to multiple G proteins
-
Chan JS, Chiu TT, Wong YH: Activation of type II adenylyl cyclase by the cloned μ-opioid receptor: Coupling to multiple G proteins. J Neurochem 1995;65:2682-2689.
-
(1995)
J Neurochem
, vol.65
, pp. 2682-2689
-
-
Chan, J.S.1
Chiu, T.T.2
Wong, Y.H.3
-
86
-
-
0029066311
-
Regulation of multiple effectors by the cloned δ-opioid receptor: Stimulation of phospholipase C and type II adenylyl cyclase
-
Tsu RC, Chan JS, Wong YH: Regulation of multiple effectors by the cloned δ-opioid receptor: Stimulation of phospholipase C and type II adenylyl cyclase. J Neurochem 1995;64:2700-2707.
-
(1995)
J Neurochem
, vol.64
, pp. 2700-2707
-
-
Tsu, R.C.1
Chan, J.S.2
Wong, Y.H.3
-
87
-
-
0036160905
-
NOC/oFQ activates PKC and generates superoxide to impair hypotensive cerebrovasodilation after hypoxia/ischemia
-
Armstead W: NOC/oFQ activates PKC and generates superoxide to impair hypotensive cerebrovasodilation after hypoxia/ischemia. Med Sci Monit 2002;8:BR8-BR14.
-
(2002)
Med Sci Monit
, vol.8
-
-
Armstead, W.1
-
88
-
-
0028981057
-
16 couple a wide variety of receptors to phospholipase C
-
16 couple a wide variety of receptors to phospholipase C. J Biol Chem 1995;270:15175-15180.
-
(1995)
J Biol Chem
, vol.270
, pp. 15175-15180
-
-
Offermanns, S.1
Simon, M.I.2
-
92
-
-
0029121976
-
Expression of alternate forms of brain opioid 'orphan' receptor mRNA in activated human peripheral blood lymphocytes and lymphocytic cell lines
-
Wick MJ, Minnerath SR, Roy S, Ramakrishnan S, Loh HH: Expression of alternate forms of brain opioid 'orphan' receptor mRNA in activated human peripheral blood lymphocytes and lymphocytic cell lines. Brain Res Mol Brain Res 1995;32:342-347.
-
(1995)
Brain Res Mol Brain Res
, vol.32
, pp. 342-347
-
-
Wick, M.J.1
Minnerath, S.R.2
Roy, S.3
Ramakrishnan, S.4
Loh, H.H.5
-
93
-
-
0031837565
-
Distribution of nociceptin/orphanin FQ receptor transcript in human central nervous system and immune cells
-
Peluso J, LaForge KS, Matthes HW, Kreek MJ, Kieffer BL, Gaveriaux-Ruff C: Distribution of nociceptin/orphanin FQ receptor transcript in human central nervous system and immune cells. J Neuroimmunol 1998;81:184-192.
-
(1998)
J Neuroimmunol
, vol.81
, pp. 184-192
-
-
Peluso, J.1
LaForge, K.S.2
Matthes, H.W.3
Kreek, M.J.4
Kieffer, B.L.5
Gaveriaux-Ruff, C.6
-
94
-
-
0029827366
-
The p38 and ERK MAP kinase pathways cooperate to activate ternary complex factors and c-fos transcription in response to UV
-
Price MA, Cruzalegui FH, Treisman R: The p38 and ERK MAP kinase pathways cooperate to activate ternary complex factors and c-fos transcription in response to UV. EMBO J 1996;15:6552-6563.
-
(1996)
EMBO J
, vol.15
, pp. 6552-6563
-
-
Price, M.A.1
Cruzalegui, F.H.2
Treisman, R.3
-
95
-
-
0025823448
-
ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF
-
Boulton TG, Nye SH, Robbins DJ, Ip NY, Radziejewska E, Morgenbesser SD, DePinho RA, Panayotatos N, Cobb MH, Yancopoulos GD: ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell 1991;65:663-675.
-
(1991)
Cell
, vol.65
, pp. 663-675
-
-
Boulton, T.G.1
Nye, S.H.2
Robbins, D.J.3
Ip, N.Y.4
Radziejewska, E.5
Morgenbesser, S.D.6
DePinho, R.A.7
Panayotatos, N.8
Cobb, M.H.9
Yancopoulos, G.D.10
-
96
-
-
0027936755
-
A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
-
Han J, Lee JD, Bibbs L, Ulevitch RJ: A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 1994;265:808-811.
-
(1994)
Science
, vol.265
, pp. 808-811
-
-
Han, J.1
Lee, J.D.2
Bibbs, L.3
Ulevitch, R.J.4
-
97
-
-
0028229012
-
The stress-activated protein kinase subfamily of c-Jun kinases
-
Kyriakis JM, Banerjee P, Nikolakaki E, Dai T, Rubie EA, Ahmad MF, Avruch J, Woodgett JR: The stress-activated protein kinase subfamily of c-Jun kinases. Nature 1994;369:156-160.
-
(1994)
Nature
, vol.369
, pp. 156-160
-
-
Kyriakis, J.M.1
Banerjee, P.2
Nikolakaki, E.3
Dai, T.4
Rubie, E.A.5
Ahmad, M.F.6
Avruch, J.7
Woodgett, J.R.8
-
99
-
-
0030796229
-
Activation of mitogen-activated protein kinase by the nociceptin receptor expressed in Chinese hamster ovary cells
-
Fukuda K, Shoda T, Morikawa H, Kato S, Mori K: Activation of mitogen-activated protein kinase by the nociceptin receptor expressed in Chinese hamster ovary cells. FEBS Lett 1997;412:290-294.
-
(1997)
FEBS Lett
, vol.412
, pp. 290-294
-
-
Fukuda, K.1
Shoda, T.2
Morikawa, H.3
Kato, S.4
Mori, K.5
-
100
-
-
0031939685
-
Nociceptin/orphanin FQ activates mitogen-activated protein kinase in Chinese hamster ovary cells expressing opioid receptor-like receptor
-
Lou LG, Zhang Z, Ma L, Pei G: Nociceptin/orphanin FQ activates mitogen-activated protein kinase in Chinese hamster ovary cells expressing opioid receptor-like receptor. J Neurochem 1998;70:1316-1322.
-
(1998)
J Neurochem
, vol.70
, pp. 1316-1322
-
-
Lou, L.G.1
Zhang, Z.2
Ma, L.3
Pei, G.4
-
101
-
-
0031815227
-
i-coupled signaling pathway: Evidence for distinct mechanisms of agonist-mediated desensitization
-
i-coupled signaling pathway: Evidence for distinct mechanisms of agonist-mediated desensitization. J Neurochem 1998;71:1024-1033.
-
(1998)
J Neurochem
, vol.71
, pp. 1024-1033
-
-
Hawes, B.E.1
Fried, S.2
Yao, X.3
Weig, B.4
Graziano, M.P.5
-
102
-
-
0032872188
-
1 receptors couple to phosphorylation and activation of p38 MAPK in NG108-15 cells and this is regulated by protein kinase A and protein kinase C
-
1 receptors couple to phosphorylation and activation of p38 MAPK in NG108-15 cells and this is regulated by protein kinase A and protein kinase C. J Neurochem 1999;73:1502-1509.
-
(1999)
J Neurochem
, vol.73
, pp. 1502-1509
-
-
Zhang, Z.1
Xin, S.M.2
Wu, G.X.3
Zhang, W.B.4
Ma, L.5
Pei, G.6
-
104
-
-
0034128416
-
Molecular mechanisms and regulation of opioid receptor signaling
-
Law PY, Wong YH, Loh HH: Molecular mechanisms and regulation of opioid receptor signaling. Annu Rev Pharmacol Toxicol 2000;40:389-430.
-
(2000)
Annu Rev Pharmacol Toxicol
, vol.40
, pp. 389-430
-
-
Law, P.Y.1
Wong, Y.H.2
Loh, H.H.3
-
105
-
-
0034832208
-
Biological significance of the JAK-STAT pathway: Lessons from knockout mice
-
Igaz P, Toth S, Falus A: Biological significance of the JAK-STAT pathway: Lessons from knockout mice. Inflamm Res 2001;50:435-441.
-
(2001)
Inflamm Res
, vol.50
, pp. 435-441
-
-
Igaz, P.1
Toth, S.2
Falus, A.3
-
106
-
-
0030950804
-
Overexpression of a neuropeptide nociceptin/orphanin FQ precursor gene, N23K/N27K, induces neurite outgrowth in mouse NS20Y cells
-
Saito Y, Maruyama K, Saido TC, Kawashima S: Overexpression of a neuropeptide nociceptin/orphanin FQ precursor gene, N23K/N27K, induces neurite outgrowth in mouse NS20Y cells. J Neurosci Res 1997;48:397-406.
-
(1997)
J Neurosci Res
, vol.48
, pp. 397-406
-
-
Saito, Y.1
Maruyama, K.2
Saido, T.C.3
Kawashima, S.4
-
107
-
-
0033523803
-
i2 proteins of v-fms-induced proliferation and transformation via Src-kinase and STAT3
-
i2 proteins of v-fms-induced proliferation and transformation via Src-kinase and STAT3. Oncogene 1999;18:6335-6342.
-
(1999)
Oncogene
, vol.18
, pp. 6335-6342
-
-
Corre, I.1
Baumann, H.2
Hermouet, S.3
-
109
-
-
0035952638
-
G protein coupled receptor signaling through the Src and Stat3 pathway: Role in proliferation and transformation
-
Ram PT, Iyengar R: G protein coupled receptor signaling through the Src and Stat3 pathway: Role in proliferation and transformation. Oncogene 2001;20:1601-1606.
-
(2001)
Oncogene
, vol.20
, pp. 1601-1606
-
-
Ram, P.T.1
Iyengar, R.2
-
110
-
-
0036371753
-
Integration of signals from receptor tyrosine kinases and G protein-coupled receptors
-
Lowes VL, Ip NY, Wong YH: Integration of signals from receptor tyrosine kinases and G protein-coupled receptors. Neurosignals 2002;11:5-19.
-
(2002)
Neurosignals
, vol.11
, pp. 5-19
-
-
Lowes, V.L.1
Ip, N.Y.2
Wong, Y.H.3
-
113
-
-
0030730929
-
2+ channel current in rat sensory neurons by a G-protein-independent mechanism
-
2+ channel current in rat sensory neurons by a G-protein-independent mechanism. J Neurosci 1997;17:8721-8728.
-
(1997)
J Neurosci
, vol.17
, pp. 8721-8728
-
-
Abdulla, F.A.1
Smith, P.A.2
-
114
-
-
0035476877
-
Nociceptin inhibits calcium channel currents in a subpopulation of small nociceptive trigeminal ganglion neurons in mouse
-
Borgland SL, Connor M, Christie MJ: Nociceptin inhibits calcium channel currents in a subpopulation of small nociceptive trigeminal ganglion neurons in mouse. J Physiol (Lond) 2001;536:35-47.
-
(2001)
J Physiol (Lond)
, vol.536
, pp. 35-47
-
-
Borgland, S.L.1
Connor, M.2
Christie, M.J.3
-
115
-
-
0029917477
-
Low-threshold calcium currents in central nervous system neurons
-
Huguenard JR: Low-threshold calcium currents in central nervous system neurons. Annu Rev Physiol 1996;58:329-348.
-
(1996)
Annu Rev Physiol
, vol.58
, pp. 329-348
-
-
Huguenard, J.R.1
-
116
-
-
0032402108
-
Axotomy reduces the effect of analgesic opioids yet increases the effect of nociceptin on dorsal root ganglion neurons
-
Abdulla FA, Smith PA: Axotomy reduces the effect of analgesic opioids yet increases the effect of nociceptin on dorsal root ganglion neurons. J Neurosci 1998;18:9685-9694.
-
(1998)
J Neurosci
, vol.18
, pp. 9685-9694
-
-
Abdulla, F.A.1
Smith, P.A.2
-
117
-
-
0028858069
-
Inhibition by spinal morphine of the tail-flick response is attenuated in rats with nerve ligation injury
-
Ossipov MH, Lopez Y, Nichols ML, Bian D, Porreca F: Inhibition by spinal morphine of the tail-flick response is attenuated in rats with nerve ligation injury. Neurosci Lett 1995;199:83-86.
-
(1995)
Neurosci Lett
, vol.199
, pp. 83-86
-
-
Ossipov, M.H.1
Lopez, Y.2
Nichols, M.L.3
Bian, D.4
Porreca, F.5
-
118
-
-
0030945213
-
1) receptor agonist, on the thermal hyperalgesia induced by unilateral constriction injury to the sciatic nerve in the rat
-
1) receptor agonist, on the thermal hyperalgesia induced by unilateral constriction injury to the sciatic nerve in the rat. Neurosci Lett 1997;224:107-110.
-
(1997)
Neurosci Lett
, vol.224
, pp. 107-110
-
-
Yamamoto, T.1
Nozaki-Taguchi, N.2
Kimura, S.3
-
119
-
-
0032104547
-
Anti-hyperalgesic and anti-allodynic effects of intrathecal nociceptin/orphanin FQ in rats after spinal cord injury, peripheral nerve injury and inflammation
-
Hao JX, Xu IS, Wiesenfeld-Hallin Z, Xu XJ: Anti-hyperalgesic and anti-allodynic effects of intrathecal nociceptin/orphanin FQ in rats after spinal cord injury, peripheral nerve injury and inflammation. Pain 1998;76:385-393.
-
(1998)
Pain
, vol.76
, pp. 385-393
-
-
Hao, J.X.1
Xu, I.S.2
Wiesenfeld-Hallin, Z.3
Xu, X.J.4
-
120
-
-
0032523741
-
2+ channel currents of acutely dissociated rat periaqueductal grey neurons
-
2+ channel currents of acutely dissociated rat periaqueductal grey neurons. J Physiol (Lond) 1998;509:47-58.
-
(1998)
J Physiol (Lond)
, vol.509
, pp. 47-58
-
-
Connor, M.1
Christie, M.J.2
-
121
-
-
0030614373
-
1 receptor ligand nociceptin on membrane properties of rat periaqueductal gray neurons in vitro
-
1 receptor ligand nociceptin on membrane properties of rat periaqueductal gray neurons in vitro. J Neurosci 1997;17:996-1003.
-
(1997)
J Neurosci
, vol.17
, pp. 996-1003
-
-
Vaughan, C.W.1
Ingram, S.L.2
Christie, M.J.3
-
122
-
-
0033406028
-
1ψ-nociceptin(1-13), nocistatin and prepronociceptin(154-181) effects on calcium channel currents and a potassium current in rat locus coeruleus in vitro
-
1ψ-nociceptin(1-13), nocistatin and prepronociceptin(154-181) effects on calcium channel currents and a potassium current in rat locus coeruleus in vitro. Br J Pharmacol 1999;128:1779-1787.
-
(1999)
Br J Pharmacol
, vol.128
, pp. 1779-1787
-
-
Connor, M.1
Vaughan, C.W.2
Jennings, E.A.3
Allen, R.G.4
Christie, M.J.5
-
124
-
-
0030003320
-
Modulation of voltage-gated calcium channels by orphanin FQ in freshly dissociated hippocampal neurons
-
Knoflach F, Reinscheid RK, Civelli O, Kemp JA: Modulation of voltage-gated calcium channels by orphanin FQ in freshly dissociated hippocampal neurons. J Neurosci 1996;16:6657-6664.
-
(1996)
J Neurosci
, vol.16
, pp. 6657-6664
-
-
Knoflach, F.1
Reinscheid, R.K.2
Civelli, O.3
Kemp, J.A.4
-
125
-
-
0031018793
-
Orphanin FQ inhibits synaptic transmission and long-term potentiation in rat hippocampus
-
Yu TP, Fein J, Phan T, Evans CJ, Xie CW: Orphanin FQ inhibits synaptic transmission and long-term potentiation in rat hippocampus. Hippocampus 1997;7:88-94.
-
(1997)
Hippocampus
, vol.7
, pp. 88-94
-
-
Yu, T.P.1
Fein, J.2
Phan, T.3
Evans, C.J.4
Xie, C.W.5
-
126
-
-
17944390583
-
Facilitation of long-term potentiation and memory in mice lacking nociceptin receptors
-
Manabe T, Noda Y, Mamiya T, Katagiri H, Houtani T, Nishi M, Noda T, Takahashi T, Sugimoto T, Nabeshima T, Takeshima H: Facilitation of long-term potentiation and memory in mice lacking nociceptin receptors. Nature 1998;394:577-581.
-
(1998)
Nature
, vol.394
, pp. 577-581
-
-
Manabe, T.1
Noda, Y.2
Mamiya, T.3
Katagiri, H.4
Houtani, T.5
Nishi, M.6
Noda, T.7
Takahashi, T.8
Sugimoto, T.9
Nabeshima, T.10
Takeshima, H.11
-
127
-
-
0029786552
-
Functional selectivity of orphanin FQ for its receptor coexpressed with potassium channel subunits in Xenopus laevis oocytes
-
Matthes H, Seward EP, Kieffer B, North RA: Functional selectivity of orphanin FQ for its receptor coexpressed with potassium channel subunits in Xenopus laevis oocytes. Mol Pharmacol 1996;50:447-450.
-
(1996)
Mol Pharmacol
, vol.50
, pp. 447-450
-
-
Matthes, H.1
Seward, E.P.2
Kieffer, B.3
North, R.A.4
-
128
-
-
0031127033
-
+ (GIRK) channel
-
+ (GIRK) channel. Brain Res Mol Brain Res 1997;45:117-126.
-
(1997)
Brain Res Mol Brain Res
, vol.45
, pp. 117-126
-
-
Ikeda, K.1
Kobayashi, K.2
Kobayashi, T.3
Ichikawa, T.4
Kumanishi, T.5
Kishida, H.6
Yano, R.7
Manabe, T.8
-
129
-
-
0030462638
-
Nociceptin receptor coupling to a potassium conductance in rat locus coeruleus neurones in vitro
-
Connor M, Vaughan CW, Chieng B, Christie MJ: Nociceptin receptor coupling to a potassium conductance in rat locus coeruleus neurones in vitro. Br J Pharmacol 1996;119:1614-1618.
-
(1996)
Br J Pharmacol
, vol.119
, pp. 1614-1618
-
-
Connor, M.1
Vaughan, C.W.2
Chieng, B.3
Christie, M.J.4
-
130
-
-
0029658923
-
+ conductance in dorsal raphe nucleus neurones
-
+ conductance in dorsal raphe nucleus neurones. Br J Pharmacol 1996;117:1609-1611.
-
(1996)
Br J Pharmacol
, vol.117
, pp. 1609-1611
-
-
Vaughan, C.W.1
Christie, M.J.2
-
131
-
-
0035809763
-
+ current induced by nociceptin in medullary dorsal horn neurons
-
+ current induced by nociceptin in medullary dorsal horn neurons. Neuroreport 2001;12:645-648.
-
(2001)
Neuroreport
, vol.12
, pp. 645-648
-
-
Jennings, E.A.1
-
134
-
-
0035448983
-
Nociceptin reduces epileptiform events in CA3 hippocampus via presynaptic and postsynaptic mechanisms
-
Tallent MK, Madamba SG, Siggins GR: Nociceptin reduces epileptiform events in CA3 hippocampus via presynaptic and postsynaptic mechanisms. J Neurosci 2001;21:6940-6948.
-
(2001)
J Neurosci
, vol.21
, pp. 6940-6948
-
-
Tallent, M.K.1
Madamba, S.G.2
Siggins, G.R.3
-
135
-
-
0034711578
-
+ channel-dependent mechanisms in piglet hypoxic/ischemic impaired nociceptin/orphanin FQ-induced cerebrovasodilation
-
+ channel-dependent mechanisms in piglet hypoxic/ischemic impaired nociceptin/orphanin FQ-induced cerebrovasodilation. Brain Res 2000;884:51-58.
-
(2000)
Brain Res
, vol.884
, pp. 51-58
-
-
Ben-Haim, G.1
Armstead, W.M.2
-
136
-
-
0030843706
-
Nociceptin/orphanin FQ stimulates extracellular acidification and desensitization of the response involves protein kinase C
-
Pei G, Ling K, Pu L, Cunningham MD, Ma L: Nociceptin/orphanin FQ stimulates extracellular acidification and desensitization of the response involves protein kinase C. FEBS Lett 1997;412:253-256.
-
(1997)
FEBS Lett
, vol.412
, pp. 253-256
-
-
Pei, G.1
Ling, K.2
Pu, L.3
Cunningham, M.D.4
Ma, L.5
-
137
-
-
0032498857
-
Attenuation of nociceptin/orphanin FQ-induced signaling by N-methyl-D-aspartate in neuronal cells
-
Zhao J, Zhang Y, Xin SM, Ma L, Pei G: Attenuation of nociceptin/orphanin FQ-induced signaling by N-methyl-D-aspartate in neuronal cells. Neuroreport 1998;9:631-636.
-
(1998)
Neuroreport
, vol.9
, pp. 631-636
-
-
Zhao, J.1
Zhang, Y.2
Xin, S.M.3
Ma, L.4
Pei, G.5
-
138
-
-
0032848993
-
Acute desensitization of nociceptin/orphanin FQ inhibition of voltage-gated calcium channels in freshly dissociated hippocampal neurons
-
Pu L, Bao GB, Ma L, Pei G: Acute desensitization of nociceptin/orphanin FQ inhibition of voltage-gated calcium channels in freshly dissociated hippocampal neurons. Eur J Neurosci 1999;11:3610-3616.
-
(1999)
Eur J Neurosci
, vol.11
, pp. 3610-3616
-
-
Pu, L.1
Bao, G.B.2
Ma, L.3
Pei, G.4
-
140
-
-
0035478438
-
Heterodimerization of G-protein-coupled receptors: Pharmacology, signaling and trafficking
-
Devi LA: Heterodimerization of G-protein-coupled receptors: Pharmacology, signaling and trafficking. Trends Pharmacol Sci 2001;22:532-537.
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 532-537
-
-
Devi, L.A.1
-
142
-
-
0034714335
-
Oligomerization of μ- and δ-opioid receptors
-
George SR, Fan T, Xie Z, Tse R, Tam V, Varghese G, O'Dowd BF: Oligomerization of μ- and δ-opioid receptors. J Biol Chem 2000;275:26128-26135.
-
(2000)
J Biol Chem
, vol.275
, pp. 26128-26135
-
-
George, S.R.1
Fan, T.2
Xie, Z.3
Tse, R.4
Tam, V.5
Varghese, G.6
O'Dowd, B.F.7
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