Address and message sequences for the nociceptin receptor: A structure- activity study of nociceptin-(1-13)-peptide amide

Journal of Medicinal Chemistry

Volumn 40, Issue 12, 1997, Pages 1789-1793

  Guerrini, Remo ^a   CalO', Girolamo ^a   Rizzi, Anna ^a   Bianchi, Clementina ^a   Lazarus, Lawrence H ^b   Salvadori, Severo ^a   Temussi, Piero A ^c   Regoli, Domenico ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DELTA OPIATE RECEPTOR ANTAGONIST; DELTORPHIN; DRUG RECEPTOR; MU OPIATE RECEPTOR AGONIST; NALOXONE; NOCICEPTIN; NOCICEPTIN RECEPTOR; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG RECEPTOR BINDING; MALE; MOUSE; NONHUMAN; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CONTRACTILITY; STRUCTURE ACTIVITY RELATION; VAS DEFERENS;

AMINO ACID SEQUENCE; ANIMALS; CYCLIC AMP; FORSKOLIN; MALE; MICE; MOLECULAR SEQUENCE DATA; NOCICEPTORS; OLIGOPEPTIDES; OPIOID PEPTIDES; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; RECEPTORS, OPIOID; STRUCTURE-ACTIVITY RELATIONSHIP; VAS DEFERENS;

EID: 0031006367     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970011b     Document Type: Article

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32. Abbreviations follow IUPAC-IUB Joint Commission on Biochemical Nomenclature for amino acids and peptides: Eur. J. Biochem. 1980, 138, 9-37. Additional abbreviations used herein are as follows: Ac, acetyl; Boc, tert-butyloxycarbonyl; DMF, N,N-dimethylformamide; Dmt, 2,6-dimethyltyrosine; Fmoc, 9-fluorenylmethyloxycarbonyl; MALDI-TOF, matrix-assisted laser desorption ionization time-of-flight; NC, nociceptin; PITC, phenyl isothiocyanate; Pmc, 2,2,5,7,8-pentamethylchroman-6-sulfonyl; tBu, tert-Butyl; TFA, trifluoroacetic acid; Tic, 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; Trt, trityl.