[Phe1Φ(CH2-NH)Gly2]nociceptin-(1-13)-NH2 acts as a partial agonist at ORL1 receptor endogenously expressed in mouse N1E-115 neuroblastoma cells

NeuroReport

Volumn 10, Issue 5, 1999, Pages 1127-1131

  Olianas, Maria C ^a   Maullu, Carlo ^a   Ingianni, Angela ^a   Onali, Pierluigi ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

CAMP; Mouse N1E 115 neuroblastoma cells; Nociceptin; Opioid receptor like (ORL1) receptor; RT PCR; 35S GTP S binding; 3H nociceptin binding; Phe1 (CH2 NH)Gly2 nociceptin (1 13) NH2

Indexed keywords

NALOXONE; NALTRINDOLE; NOCICEPTIN; NOCICEPTIN DERIVATIVE; NOCICEPTIN(1-13)[1 PHENYLALANINE PSI (METHYLAMIDE) 2 GLYCINE] AMIDE; NORBINALTORPHIMINE; OPIATE AGONIST; UNCLASSIFIED DRUG; CYCLIC AMP; FORSKOLIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); NOCICEPTIN (1 13) NH2, PHE(1) PSI(CH2 NH) GLY(2); NOCICEPTIN (1-13)-NH2, PHE(1)-PSI(CH2-NH)-GLY(2)-; NOCICEPTIN RECEPTOR; OPIATE PEPTIDE; OPIATE RECEPTOR; PEPTIDE FRAGMENT;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; MOUSE; NEUROBLASTOMA; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DRUG ANTAGONISM; DRUG COMBINATION; DRUG POTENTIATION; METABOLISM; PATHOLOGY;

ANIMALS; CYCLIC AMP; DRUG COMBINATIONS; FORSKOLIN; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); MICE; NEUROBLASTOMA; OPIOID PEPTIDES; PEPTIDE FRAGMENTS; RECEPTORS, OPIOID; TUMOR CELLS, CULTURED;

EID: 0033528558     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-199904060-00041     Document Type: Article

References (18)

1. Meunier JC, Mollerau C. Toll L et al. Nature 377, 532-535 (1995).
2. Reinscheid RK, Nothacker H-P, Bourson A et al. Science 270, 792-794 (1995).
3. Meunier J-C. Eur J Pharmacol 340, 1-15 (1997).
4. Guerrini R, Calo G, Rizzi A et al. Br J Pharmacol 123, 163-165 (1998).
5. Butour J-L, Moisand C, Mollerau C and Meunier J-C. Eur J Pharmacol 349, R5-R6 (1998).
6. Grisel JE, Farrier DE, Wilson SG and Mogil JS. Eur J Pharmacol 357, R1-R3 (1998).
7. Matthes H, Seward EP, Kieffer B and North RA. Mol Pharmacol 50, 447-450 (1996).
8. Salomon Y. Adv Cyclic Nucleotide Res 10, 35-52 (1979).
9. Bradford MM. Anal Biochem72, 248-254 (1976).
10. Cheng Y-C and Prusoff WH. Biochem Pharmacol 22, 3099-3108 (1973).
11. Munson PJ and Rodbard D. Anal Biochem 107, 220-239 (1980).
12. Mathis JP, Ryan-Moro J, Chang A et al. Biochem Biophys Res Commun 230, 462-465 (1997).
13. Okawa H, Hirst RA, Smart D, McKnight AT et al. Neurosci Lett 246, 49-52 (1998).
14. Adapa ID and Toll L. Neuropeptides 31, 403-408 (1997).
15. Sim LJ, Xiao R and Childers SR. NeuroReport 7, 729-733 (1996).
16. Gilbert JA, Knodel EL, Sternstrom SD et al. J Biol Chem 257, 1274-1281 (1982).
17. Prather PL. Loh HH and Law PY. Mol Pharmacol 45, 997-1003 (1994).
18. Kenakin TP, Bond RA and Bonner TI. Pharmacol Rev 44, 351-362 (1992).