Overexpression of a neuropeptide nociceptin/orphanin FQ precursor gene, N23K/N27K, induces neurite outgrowth in mouse NS20Y cells

Journal of Neuroscience Research

Volumn 48, Issue 5, 1997, Pages 397-406

  Saito, Y ^a   Maruyama, K ^a,b   Saido, T C ^a   Kawashima, S ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

Author keywords

differentiation; neuroblastoma; opioid; precursor protein; secretopgranin I; transfection

Indexed keywords

BUCLADESINE; CHROMOGRANIN B; NOCICEPTIN; OPIATE PEPTIDE; ORPHANIN FQ PROTEIN; PROTEIN 27K; PROTEIN N 23 K; PROTEIN PRECURSOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; MOUSE; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NEURITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; DNA, COMPLEMENTARY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; MICE; MOLECULAR SEQUENCE DATA; NEURITES; NEUROBLASTOMA; NEUROPEPTIDES; OPIOID PEPTIDES; PROTEIN PRECURSORS; RECEPTORS, OPIOID; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0030950804     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19970601)48:5<397::AID-JNR2>3.0.CO;2-9     Document Type: Article

References (25)

1. Amano T, Richelson E, Nirenberg M (1972): Neurotransmitter synthesis by neuroblastoma clones. Proc Natl Acad Sci USA 69:258-263.
2. Bunzow JR, Saez C, Mortrud M, Bonvier C, Williams JT, Low M, Grandy DK (1994): Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a μ, δ, and κ opioid receptor type. FEBS Lett 347:284-288.
3. Chen Y, Fan Y, Liu J, Mestek A, Tian M, Kozak CA, Yu L (1994): Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family. FEBS Lett 347:279-283.
4. Fukuda K, Kato S, Mori K, Nishi M, Takeshima H, Iwabe N, Miyata T, Houtani T, Sugimoto T (1994): cDNA cloning and regional distribution of a novel member of the opioid receptor family. FEBS Lett 343:42-46.
5. 2+/calmodulin-dependent protein kinase II in Neuro2a and NG108-15 neuroblastoma cell lines promotes neurite outgrowth and growth cone motility. J Neurosci 13:559-567.
6. Hauser KF (1992): Morphine regulates DNA synthesis in rat cerebellar neuroblasts in vitro. Dev Brain Res 70:291-297.
7. Houtani T, Nishi M, Takeshima H, Nukada T, Sugimoto T (1996): Structure and regional distribution of nociceptin/orphanin FQ precursor. Biochem Biophys Res Commun 219:714-719.
8. Kirshner JA, Markelonis GJ, Max SR (1986): Effects of cell division, cell density, and cyclic nucleotides on choline acetyltransferase activity in a cholinergic neuroblastoma cell line (S-20Y). J Neurochem 46:817-821.
9. Kringlstein K, Unsicker K (1996): Proteins from chromaffin granules promote survival of dorsal root ganglionic neurons: Comparison with neurotrophins. Dev Brain Res 93:10-17.
10. Lachowicz JE, Shen Y, Monsma FL Jr, Sibley DR (1995): Molecular cloning of a novel G protein-coupled receptor related to the opiate receptor family. J Neurochem 64:34-40.
11. Melner M, Low KH, Allen RG, Nielsen CP, Young SL, Saneto RP (1990): The regulation of proenkephalin expression in a distinct population in glial cells. EMBO J 9:791-796.
12. Meunier J-C, Mollereau C, Toll L, Suaudeau C, Moisand C, Alvinerie P, Butour J-L, Guillemont J-C, Ferrara P, Monsarrat B, Mazarguil H, Vassart G, Parmentier M, Costentin J (1995): Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature 377:532-535.
13. Mollereau C, Parmentier M, Mailleux P, Butour J-L, Moisand C, Chalon P, Caput D, Vassart G, Meunier J-C (1994): ORL1, a novel member of the opioid receptor family: Cloning, functional expression and localization. FEBS Lett 341:33-38.
14. Mollereau C, Simons M-J, Soularue P, Liners F, Vassart G, Meunier J-C, Parmentier M (1996): Structure, tissue distribution, and chromosomal localization of the prepronociceptin gene. Proc Natl Acad Sci USA 93:8666-8670.
15. Nothacker H-P, Reinscheid RK, Mansour A, Henningsen RA, Ardati A, Monsma FL Jr, Watson SJ, Civelli O (1996): Primary structure and tissue distribution of the orphanin FQ precursor. Proc Natl Acad Sci USA 93:8677-8682.
16. Pan Y-X, Xu J, Pasternak GW (1996): Cloning and expression of a cDNA encoding a mouse brain orphanin FQ/nociceptin precursor. Biochem J 315:11-13.
17. Reinscheid RK, Nothacker H-P, Bourson A, Ardati A., Henningsen RA, Bunzow JR, Grandy DK, Langen H, Monsma JJR, Civelli O (1995): Orphanin FQ: A neuropeptide that activates an opioid-like G protein-coupled receptor. Science 270:792-794.
18. Saito Y, Maruyama K, Saido TC, Kawashima S (1995): N23K, a gene transiently up-regulated during neural differentiation, encodes a precursor protein for a newly identified neuropeptide nociceptin. Biochem Biophys Res Commun 217:539-545.
19. Saito Y, Maruyama K, Kawano H, Hagino-Yamagishi K, Kawamura K, Saido TC, Kawashima S (1996): Molecular cloning and characterization of a novel form of neuropeptide gene as a developmentally regulated molecule. J Biol Chem 271:15615-15622.
20. Spruce BA, Curtis R, Wilkin G, Glover DM (1990): A neuropeptide precursor in cerebellum: Proenkephalin exists in subpopulations of both neurons and astrocytes. EMBO J 9:1787-1795.
21. Wang JB, Johnson PS, Imai Y, Persico AM, Ozenberger BA, Eppler CM, Uhl GR (1994): cDNA cloning of an orphan receptor gene family member and its splice variant. FEBS Lett 348:75-79.
22. Wick MJ, Minnerath SR, Lin X, Elde R, Law P-Y, Loh HH (1994): Isolation of a novel cDNA encoding a putative membrane receptor with high homology to the cloned μ, δ, and κ opioid receptors. Mol Brain Res 27:37-44.
23. Winkler H (1993): The adrenal chromaffin granule: A model for large dense core vesicles of endocrine and nervous tissue. J Anat 183:237-252.
24. Zagon IS, McLaughlin PJ (1989): Endogenous opioid systems regulate growth of neural tumor cells in culture. Brain Res 490:14-25.
25. Zagon IS, Rhodes RE, McLaughlin PJ (1985): Distribution of enkephalin I immunoreactivity in germinative cells of developing rat cerebellum. Science 227:1049-1051.