High-affinity, non-peptide agonists for the ORL1 (Orphanin FQ/nociceptin) receptor

Journal of Medicinal Chemistry

Volumn 43, Issue 7, 2000, Pages 1329-1338

  Röver, Stephan ^a,b   Adam, Geo ^a   Cesura, Andrea M ^a   Galley, Guido ^a   Jenck, François ^a   Monsma Jr , Frederick J ^a,c   Wichmann, Jürgen ^a   Dautzenberg, Frank M ^a  

^a Preclinical Research   (Switzerland)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 (5 METHYL 1,2,3,4 TETRAHYDRO NAPHTHALEN 1 YL) 1 PHENYL 1,3,8 TRIAZASPIRO[4.5]DECAN 4 ONE; 8 ACENAPHTEN 1 YL 1 PHENYL 1,3,8 TRIAZASPIRO[4.5]DECAN 4 ONE; NAPHTHALENE DERIVATIVE; NOCICEPTIN RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

BINDING, COMPETITIVE; CELL LINE; HUMANS; IMIDAZOLES; LIGANDS; RADIOLIGAND ASSAY; RECEPTORS, OPIOID; SPIRO COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0342749308     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm991129q     Document Type: Article

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