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Volumn 11, Issue 1, 2002, Pages 5-19

Integration of signals from receptor tyrosine kinases and G protein-coupled receptors

Author keywords

G protein; MAPK; Receptor; Signaling; Tyrosine kinase

Indexed keywords

ADAPTOR PROTEIN; BETA ARRESTIN; CYCLIC AMP; CYTOCHALASIN D; EPIDERMAL GROWTH FACTOR RECEPTOR; G PROTEIN COUPLED RECEPTOR; GONADORELIN; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; GUANOSINE TRIPHOSPHATASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE C; PROTEIN SHC; PROTEIN SUBUNIT; PROTEIN TYROSINE KINASE; RAF PROTEIN; RAP PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SOMATOMEDIN C; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 0036371753     PISSN: 1424862X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000057317     Document Type: Review
Times cited : (125)

References (114)
  • 1
    • 0028860268 scopus 로고
    • Heterotrimer G proteins: Organizers of transmembrane signals
    • Neer EJ: Heterotrimer G proteins: Organizers of transmembrane signals. Cell 1995;80:249-257.
    • (1995) Cell , vol.80 , pp. 249-257
    • Neer, E.J.1
  • 2
    • 0031984517 scopus 로고    scopus 로고
    • The many faces of G protein signaling
    • Hamm HE: The many faces of G protein signaling. J Biol Chem 1998;273:669-672.
    • (1998) J Biol Chem , vol.273 , pp. 669-672
    • Hamm, H.E.1
  • 3
    • 0029940555 scopus 로고    scopus 로고
    • The neurotrophins and CNTF: Two families of collaborative neutrotrophic factors
    • Ip NY, Yancopoulos GD: The neurotrophins and CNTF: Two families of collaborative neutrotrophic factors. Annu Rev Neurosci 1996; 19:491-515.
    • (1996) Annu Rev Neurosci , vol.19 , pp. 491-515
    • Ip, N.Y.1    Yancopoulos, G.D.2
  • 6
    • 0034644539 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Schlessinger J: Cell signaling by receptor tyrosine kinases. Cell 2000;103:211-225.
    • (2000) Cell , vol.103 , pp. 211-225
    • Schlessinger, J.1
  • 7
    • 0032910168 scopus 로고    scopus 로고
    • Organization and regulation of mitogen-activated protein kinase signaling pathway
    • Garringon TP, Johnson GL: Organization and regulation of mitogen-activated protein kinase signaling pathway. Curr Opin Cell Biol 1999; 11:211-218.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 211-218
    • Garringon, T.P.1    Johnson, G.L.2
  • 8
    • 0029011084 scopus 로고
    • G protein-coupled receptor systems involved in cell growth and oncogenesis
    • Dhanasekaran N, Heasley LE, Johnson GL: G protein-coupled receptor systems involved in cell growth and oncogenesis. Endocrinol Rev 1995;16:259-270.
    • (1995) Endocrinol Rev , vol.16 , pp. 259-270
    • Dhanasekaran, N.1    Heasley, L.E.2    Johnson, G.L.3
  • 9
    • 0026318020 scopus 로고
    • G-protein-coupled receptor genes as protooncogenes: Constitutively activating mutation of the α1B-adrenergic receptor enhances mitogenesis and tumorigenicity
    • Allen LF, Lefkowitz RJ, Caron MG, Cotecchia S: G-protein-coupled receptor genes as protooncogenes: Constitutively activating mutation of the α1B-adrenergic receptor enhances mitogenesis and tumorigenicity. Proc Natl Acad Sci USA 1991;88:11354-11358.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 11354-11358
    • Allen, L.F.1    Lefkowitz, R.J.2    Caron, M.G.3    Cotecchia, S.4
  • 12
    • 0032910337 scopus 로고    scopus 로고
    • Interactions between mitogenic stimuli, or a thousand and one connections
    • Schwartz MA, Baron V: Interactions between mitogenic stimuli, or a thousand and one connections. Curr Opin Cell Biol 1999;11:197-202.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 197-202
    • Schwartz, M.A.1    Baron, V.2
  • 13
    • 0032617493 scopus 로고    scopus 로고
    • Protein tyrosine kinase-mediated pathways in G protein-coupled receptor signaling
    • Dikic I, Blaukat A: Protein tyrosine kinase-mediated pathways in G protein-coupled receptor signaling. Cell Biochem Biophys 1999; 30:369-387.
    • (1999) Cell Biochem Biophys , vol.30 , pp. 369-387
    • Dikic, I.1    Blaukat, A.2
  • 14
    • 0028240869 scopus 로고
    • Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits
    • Crespo P, Xu N, Simonds WF, Gutkind JS: Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits. Nature 1994;369:418-420.
    • (1994) Nature , vol.369 , pp. 418-420
    • Crespo, P.1    Xu, N.2    Simonds, W.F.3    Gutkind, J.S.4
  • 19
    • 0029778177 scopus 로고    scopus 로고
    • Role of c-Src tyrosine kinase in G protein-coupled receptor-and Gβγ subunit-mediated activation of mitogen-activated protein kinases
    • Luttrell LM, Hawes BE, van Biesen T, Luttrell DK, Lansing TJ, Lefkowitz RJ: Role of c-Src tyrosine kinase in G protein-coupled receptor-and Gβγ subunit-mediated activation of mitogen-activated protein kinases. J Biol Chem 1996;271:19443-19450.
    • (1996) J Biol Chem , vol.271 , pp. 19443-19450
    • Luttrell, L.M.1    Hawes, B.E.2    Van Biesen, T.3    Luttrell, D.K.4    Lansing, T.J.5    Lefkowitz, R.J.6
  • 20
    • 0031037296 scopus 로고    scopus 로고
    • Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase γ
    • Lopez-Ilasaca M, Crespo P, Pellici PG, Gutkind JS, Wetzker R: Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase γ. Science 1997;275:394-397.
    • (1997) Science , vol.275 , pp. 394-397
    • Lopez-Ilasaca, M.1    Crespo, P.2    Pellici, P.G.3    Gutkind, J.S.4    Wetzker, R.5
  • 21
    • 0028198388 scopus 로고
    • Activation of phosphatidylinositol-3′ kinase by Src-family kinases SH3 binding to the p85 subunit
    • Pleiman CM, Hertz WM, Cambier JC: Activation of phosphatidylinositol- 3′ kinase by Src-family kinases SH3 binding to the p85 subunit. Science 1994;263:1609-1612.
    • (1994) Science , vol.263 , pp. 1609-1612
    • Pleiman, C.M.1    Hertz, W.M.2    Cambier, J.C.3
  • 22
    • 0028176297 scopus 로고
    • cAMP and βγ subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells
    • Faure M, Voyno-Yasenetskaya TA, Bourne HR: cAMP and βγ subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells. J Biol Chem 1994;269:7851-7854.
    • (1994) J Biol Chem , vol.269 , pp. 7851-7854
    • Faure, M.1    Voyno-Yasenetskaya, T.A.2    Bourne, H.R.3
  • 23
    • 0028973270 scopus 로고
    • Dual effect of β-adrenergic receptors on mitogen-activated protein kinase
    • Crespo P, Cachero TG, Xu N, Gutking JS: Dual effect of β-adrenergic receptors on mitogen-activated protein kinase. J Biol Chem 1995;270:25259-25265.
    • (1995) J Biol Chem , vol.270 , pp. 25259-25265
    • Crespo, P.1    Cachero, T.G.2    Xu, N.3    Gutking, J.S.4
  • 24
    • 0032485938 scopus 로고    scopus 로고
    • s/mitogen activated protein kinase pathway in mutant S49 cells
    • s/mitogen activated protein kinase pathway in mutant S49 cells. J Biol Chem 1998;273:14533-14537.
    • (1998) J Biol Chem , vol.273 , pp. 14533-14537
    • Wan, Y.1    Huang, X.-Y.2
  • 25
    • 0027772672 scopus 로고
    • Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphate
    • Wu J, Dent P, Jelinek T, Wolfman A, Weber MJ, Sturgill TW: Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′- monophosphate. Science 1993;262: 1065-1069.
    • (1993) Science , vol.262 , pp. 1065-1069
    • Wu, J.1    Dent, P.2    Jelinek, T.3    Wolfman, A.4    Weber, M.J.5    Sturgill, T.W.6
  • 26
    • 0027716596 scopus 로고
    • Inhibition by cAMP of Ras-dependent activation of Raf
    • Cook SJ, McCormick F: Inhibition by cAMP of Ras-dependent activation of Raf. Science 1993;262:1069-1072.
    • (1993) Science , vol.262 , pp. 1069-1072
    • Cook, S.J.1    McCormick, F.2
  • 27
    • 0028986878 scopus 로고
    • s/protein kinase A and the Ras/MAP-kinase signalling pathways
    • s/protein kinase A and the Ras/MAP-kinase signalling pathways. Biochem Soc Trans 1995;23:129-133.
    • (1995) Biochem Soc Trans , vol.23 , pp. 129-133
    • Chen, J.1    Iyengar, R.2
  • 28
    • 0030613761 scopus 로고    scopus 로고
    • 2-adrenergic receptor to different G proteins by protein kinase A
    • 2-adrenergic receptor to different G proteins by protein kinase A. Nature 1997;390:88-91.
    • (1997) Nature , vol.390 , pp. 88-91
    • Daaka, Y.1    Luttrell, L.M.2    Lefkowitz, R.J.3
  • 29
    • 0029907265 scopus 로고    scopus 로고
    • A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation
    • Dikic I, Tokiwa G, Lev S, Courtneidge SA, Schlessinger J: A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation. Nature 1996;383:547-550.
    • (1996) Nature , vol.383 , pp. 547-550
    • Dikic, I.1    Tokiwa, G.2    Lev, S.3    Courtneidge, S.A.4    Schlessinger, J.5
  • 32
    • 0032478610 scopus 로고    scopus 로고
    • Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein kinase C
    • Marais R, Light Y, Mason C, Paterson H, Olson MF, Marshall CJ: Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein kinase C. Science 1998;280:109-112.
    • (1998) Science , vol.280 , pp. 109-112
    • Marais, R.1    Light, Y.2    Mason, C.3    Paterson, H.4    Olson, M.F.5    Marshall, C.J.6
  • 33
    • 0027982408 scopus 로고
    • Thyrotropin-releasing hormone stimulated MAP kinase activity in GH3 cells by divergent pathways
    • Ohmichi M, Sawada T, Kanda Y, Koike K, Hirota K, Miyake A, Saltiel AR: Thyrotropin-releasing hormone stimulated MAP kinase activity in GH3 cells by divergent pathways. J Biol Chem 1994;269:3783-3788.
    • (1994) J Biol Chem , vol.269 , pp. 3783-3788
    • Ohmichi, M.1    Sawada, T.2    Kanda, Y.3    Koike, K.4    Hirota, K.5    Miyake, A.6    Saltiel, A.R.7
  • 34
    • 0031956113 scopus 로고    scopus 로고
    • A G protein βγ dimer-mediated pathway contributes to mitogen-activated protein-kinase activation by thyrotropin releasing hormone receptors in transfected COS-7 cells
    • Palomero T, Barros F, del Camino D, Viloria CG, de la Pena P: A G protein βγ dimer-mediated pathway contributes to mitogen-activated protein-kinase activation by thyrotropin releasing hormone receptors in transfected COS-7 cells. Mol Pharmacol 1998;53:613-622.
    • (1998) Mol Pharmacol , vol.53 , pp. 613-622
    • Palomero, T.1    Barros, F.2    Del Camino, D.3    Viloria, C.G.4    De La Pena, P.5
  • 35
    • 0035895872 scopus 로고    scopus 로고
    • Role of dynamin, Src, and Ras in the protein kinase C-mediated activation of ERK by gonadotropin-releasing hormone
    • Benard O, Naor Z, Seger R: Role of dynamin, Src, and Ras in the protein kinase C-mediated activation of ERK by gonadotropin-releasing hormone. J Biol Chem 2001;276:4554-4563.
    • (2001) J Biol Chem , vol.276 , pp. 4554-4563
    • Benard, O.1    Naor, Z.2    Seger, R.3
  • 36
    • 0034697039 scopus 로고    scopus 로고
    • Epidermal growth factor receptor tyrosine kinase mediates Ras activation by gonadotropin-releasing hormone
    • Grosse R, Roelle S, Herrlich A, Höhn J, Gudermann T: Epidermal growth factor receptor tyrosine kinase mediates Ras activation by gonadotropin-releasing hormone. J Biol Chem 2000;275:12251-12260.
    • (2000) J Biol Chem , vol.275 , pp. 12251-12260
    • Grosse, R.1    Roelle, S.2    Herrlich, A.3    Höhn, J.4    Gudermann, T.5
  • 37
    • 0035895958 scopus 로고    scopus 로고
    • q/11-coupled m3-muscarinic receptor is involved in receptor activation of the ERK-1/2 mitogen-activated protein kinase pathway
    • q/11-coupled m3-muscarinic receptor is involved in receptor activation of the ERK-1/2 mitogen-activated protein kinase pathway. J Biol Chem 2001;276:4581-4587.
    • (2001) J Biol Chem , vol.276 , pp. 4581-4587
    • Budd, D.C.1    Willars, G.B.2    McDonald, J.E.3    Tobin, A.B.4
  • 38
    • 0030044360 scopus 로고    scopus 로고
    • Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
    • Daub H, Weiss FU, Wallasch C, Ullrich A: Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors. Nature 1996;379:557-560.
    • (1996) Nature , vol.379 , pp. 557-560
    • Daub, H.1    Weiss, F.U.2    Wallasch, C.3    Ullrich, A.4
  • 39
    • 0030770603 scopus 로고    scopus 로고
    • Critical role of calcium-dependent epidermal growth factor transactivation in PC12 cell membrane depolarization and bradykinin sginaling
    • Zwick E, Daub H, Aoki N, Yamaguchi-Aoki Y, Tinhofer I, Maly K, Ullrich A: Critical role of calcium-dependent epidermal growth factor transactivation in PC12 cell membrane depolarization and bradykinin sginaling. J Biol Chem 1997;272:2467-24770.
    • (1997) J Biol Chem , vol.272 , pp. 2467-24770
    • Zwick, E.1    Daub, H.2    Aoki, N.3    Yamaguchi-Aoki, Y.4    Tinhofer, I.5    Maly, K.6    Ullrich, A.7
  • 40
    • 0035141154 scopus 로고    scopus 로고
    • i coupling and Src-dependent phosphorylation of the epidermal growth factor receptor
    • i coupling and Src-dependent phosphorylation of the epidermal growth factor receptor. J Pharmacol Exp Ther 2001;296:426-433.
    • (2001) J Pharmacol Exp Ther , vol.296 , pp. 426-433
    • Gao, Y.1    Tang, S.2    Zhou, S.3    Ware, J.A.4
  • 41
    • 0032555202 scopus 로고    scopus 로고
    • Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic acid-stimulated mitogenic activity in L cells
    • Herrlich A, Daub H, Knebel A, Herrlich P, Ullrich A, Schultz G, Gudermann T: Ligand-independent activation of platelet-derived growth factor receptor is a necessary intermediate in lysophosphatidic acid-stimulated mitogenic activity in L cells. Proc Natl Acad Sci USA 1998;95:8985-8990.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8985-8990
    • Herrlich, A.1    Daub, H.2    Knebel, A.3    Herrlich, P.4    Ullrich, A.5    Schultz, G.6    Gudermann, T.7
  • 42
    • 0033599039 scopus 로고    scopus 로고
    • EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
    • Prenzel N, Zwich E, Daub H, Leserer M, Abraham R, Wallasch C, Ullrich A: EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 1999;402:884-888.
    • (1999) Nature , vol.402 , pp. 884-888
    • Prenzel, N.1    Zwich, E.2    Daub, H.3    Leserer, M.4    Abraham, R.5    Wallasch, C.6    Ullrich, A.7
  • 43
    • 0035896502 scopus 로고    scopus 로고
    • Activation of MAPKs by angiotensin II in vascular smooth muscle cells
    • Eguchi S, Dempsey PJ, Frank GD, Motley ED, Inagami T: Activation of MAPKs by angioten-sin II in vascular smooth muscle cells. J Biol Chem 2001;276:7957-7962.
    • (2001) J Biol Chem , vol.276 , pp. 7957-7962
    • Eguchi, S.1    Dempsey, P.J.2    Frank, G.D.3    Motley, E.D.4    Inagami, T.5
  • 46
    • 0034689003 scopus 로고    scopus 로고
    • β-Arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2
    • DeFea KA, Zalevsky J, Thoma MS, Déry O, Mullins RD, Bunnett NW: β-Arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2. J Cell Biol 2000;148:1267-1281.
    • (2000) J Cell Biol , vol.148 , pp. 1267-1281
    • DeFea, K.A.1    Zalevsky, J.2    Thoma, M.S.3    Déry, O.4    Mullins, R.D.5    Bunnett, N.W.6
  • 47
    • 0033553526 scopus 로고    scopus 로고
    • Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases
    • Della Rocca GJ, Maudsley S, Daaka Y, Lefkowitz RJ, Luttrell LM: Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases. J Biol Chem 1999;274:13978-13984.
    • (1999) J Biol Chem , vol.274 , pp. 13978-13984
    • Della Rocca, G.J.1    Maudsley, S.2    Daaka, Y.3    Lefkowitz, R.J.4    Luttrell, L.M.5
  • 49
    • 0027153594 scopus 로고
    • Bombesin stimulation of p125 focal adhesion kinase tyrosine phosphorylation
    • Sinnet-Smith J, Zachary I, Valverde AM, Rozengurt E: Bombesin stimulation of p125 focal adhesion kinase tyrosine phosphorylation. J Biol Chem 1993;268:14261-14268.
    • (1993) J Biol Chem , vol.268 , pp. 14261-14268
    • Sinnet-Smith, J.1    Zachary, I.2    Valverde, A.M.3    Rozengurt, E.4
  • 50
    • 0032563218 scopus 로고    scopus 로고
    • Bombesin, vasopressin, lysophosphatidic acid, and sphingosylphosphorylcholine induce focal adhesion kinase activation in intact Swiss 3T3 cells
    • Rodríguez-Fernández JL, Rozengurt E: Bombesin, vasopressin, lysophosphatidic acid, and sphingosylphosphorylcholine induce focal adhesion kinase activation in intact Swiss 3T3 cells. J Biol Chem 1998;273:19321-19328.
    • (1998) J Biol Chem , vol.273 , pp. 19321-19328
    • Rodríguez-Fernández, J.L.1    Rozengurt, E.2
  • 51
    • 0031438076 scopus 로고    scopus 로고
    • G protein-coupled receptors mediate two functionally distinct pathways of tyrosine phosphorylation in rat 1a fibroblasts. Shc phosphorylation and receptor endocytosis correlate with activation of Erk kinases
    • Luttrell LM, Daaka Y, Della Rocca GJ, Lefkowitz RJ: G protein-coupled receptors mediate two functionally distinct pathways of tyrosine phosphorylation in rat 1a fibroblasts. Shc phosphorylation and receptor endocytosis correlate with activation of Erk kinases. J Biol Chem 1997;272:31648-31656.
    • (1997) J Biol Chem , vol.272 , pp. 31648-31656
    • Luttrell, L.M.1    Daaka, Y.2    Della Rocca, G.J.3    Lefkowitz, R.J.4
  • 52
    • 0029148780 scopus 로고
    • G protein-coupled chemoattractant receptors regulate Lyn tyrosine kinase-Shc adapter protein signaling complexes
    • Ptasznik A, Traynor-Kaplan A, Bokoch GM: G protein-coupled chemoattractant receptors regulate Lyn tyrosine kinase-Shc adapter protein signaling complexes. J Biol Chem 1995;270:19969-19973.
    • (1995) J Biol Chem , vol.270 , pp. 19969-19973
    • Ptasznik, A.1    Traynor-Kaplan, A.2    Bokoch, G.M.3
  • 53
    • 0029892373 scopus 로고    scopus 로고
    • Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors
    • Wan Y, Kurosaki T, Huang XY: Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors. Nature 1996;380:541-544.
    • (1996) Nature , vol.380 , pp. 541-544
    • Wan, Y.1    Kurosaki, T.2    Huang, X.Y.3
  • 54
    • 9444242667 scopus 로고    scopus 로고
    • G-protein βγ subunits mediate specific phosphorylation of the protein-tyrosine phosphatase SH-PTP1 induced by lysophosphatidic acid
    • Gaits F, Li RY, Bigay J, Ragab A, Ragab-Thomas JMF, Chap H: G-protein βγ subunits mediate specific phosphorylation of the protein-tyrosine phosphatase SH-PTP1 induced by lysophosphatidic acid. J Biol Chem 1996;271:20151-20155.
    • (1996) J Biol Chem , vol.271 , pp. 20151-20155
    • Gaits, F.1    Li, R.Y.2    Bigay, J.3    Ragab, A.4    Ragab-Thomas, J.M.F.5    Chap, H.6
  • 55
    • 0029664925 scopus 로고    scopus 로고
    • Phosphorylation-dependent activation of the Ras-GRF/CDC25Mm exchange factor by muscarinic receptors and G-protein βγ subunits
    • Mattingly RR, Macara IG: Phosphorylation-dependent activation of the Ras-GRF/ CDC25Mm exchange factor by muscarinic receptors and G-protein βγ subunits. Nature 1996;382:268-272.
    • (1996) Nature , vol.382 , pp. 268-272
    • Mattingly, R.R.1    Macara, I.G.2
  • 56
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • Davis RJ: Signal transduction by the JNK group of MAP kinases. Cell 2000;103:239-252.
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 59
    • 0029002666 scopus 로고
    • Differential calcium dependence in the activation of c-Jun kinase and mitogen-activated protein kinase by muscarinic acetylcholine receptors in rat 1a cells
    • Mitchell FM, Russell M, Johnson GL: Differential calcium dependence in the activation of c-Jun kinase and mitogen-activated protein kinase by muscarinic acetylcholine receptors in rat 1a cells. Biochem J 1995;309:381-384.
    • (1995) Biochem J , vol.309 , pp. 381-384
    • Mitchell, F.M.1    Russell, M.2    Johnson, G.L.3
  • 60
    • 0030047481 scopus 로고    scopus 로고
    • Signaling from G protein-coupled receptors to c-Jun kinase involves βγ subunits of heterotrimeric G proteins acting on a Ras and Rac-1 dependent pathway
    • Coso OA, Teramoto H, Simonds WF, Gutkind JS: Signaling from G protein-coupled receptors to c-Jun kinase involves βγ subunits of heterotrimeric G proteins acting on a Ras and Rac-1 dependent pathway. J Biol Chem 1996;271:3963-3966.
    • (1996) J Biol Chem , vol.271 , pp. 3963-3966
    • Coso, O.A.1    Teramoto, H.2    Simonds, W.F.3    Gutkind, J.S.4
  • 62
    • 0034677951 scopus 로고    scopus 로고
    • i-dependent activation of c-Jun N-terminal kinase in human embryonal kidney 293 cells
    • i-dependent activation of c-Jun N-terminal kinase in human embryonal kidney 293 cells. J Biol Chem 2000;275:7633-7640.
    • (2000) J Biol Chem , vol.275 , pp. 7633-7640
    • Yamauchi, J.1    Kawano, T.2    Nagao, M.3    Kaziro, Y.4    Itoh, H.5
  • 63
    • 0033593501 scopus 로고    scopus 로고
    • Differential regulation of mitogen-activated protein kinase kinase 4 (MKK4) and 7 (MKK7) by signaling from G protein βγ subunit in human embryonal kidney 293 cells
    • Yamauchi J, Kaziro Y, Itoh H: Differential regulation of mitogen-activated protein kinase kinase 4 (MKK4) and 7 (MKK7) by signaling from G protein βγ subunit in human embryonal kidney 293 cells. J Biol Chem 1999;274:1957-1965.
    • (1999) J Biol Chem , vol.274 , pp. 1957-1965
    • Yamauchi, J.1    Kaziro, Y.2    Itoh, H.3
  • 64
    • 0029070887 scopus 로고
    • Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs
    • Minden A, Lin A, Claret FX, Abo A, Karin M: Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell 1995;81:1147-1157.
    • (1995) Cell , vol.81 , pp. 1147-1157
    • Minden, A.1    Lin, A.2    Claret, F.X.3    Abo, A.4    Karin, M.5
  • 65
    • 0029055812 scopus 로고
    • The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
    • Coso OA, Chiariello M, Yu J-C, Teramoto H, Crespo P, Xu N, Miki T, Gutkind JS: The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell 1995;81:1137-1146.
    • (1995) Cell , vol.81 , pp. 1137-1146
    • Coso, O.A.1    Chiariello, M.2    Yu, J.-C.3    Teramoto, H.4    Crespo, P.5    Xu, N.6    Miki, T.7    Gutkind, J.S.8
  • 66
    • 0029666415 scopus 로고    scopus 로고
    • 12 stimulates c-Jun NH2-terminal kinase through the small G proteins Ras and Rac
    • 12 stimulates c-Jun NH2-terminal kinase through the small G proteins Ras and Rac. J Biol Chem 1996;271:17349-17353.
    • (1996) J Biol Chem , vol.271 , pp. 17349-17353
    • Collins, L.R.1    Minden, A.2    Karin, M.3    Heller Brown, J.4
  • 67
    • 0033696482 scopus 로고    scopus 로고
    • Regulation of c-Jun N-terminal kinase by the ORL1 receptor through multiple G proteins
    • Chan ASL, Wong YH: Regulation of c-Jun N-terminal kinase by the ORL1 receptor through multiple G proteins. J Pharmacol Exp Ther 2000;295:1094-1100.
    • (2000) J Pharmacol Exp Ther , vol.295 , pp. 1094-1100
    • Chan, A.S.L.1    Wong, Y.H.2
  • 68
    • 0028875683 scopus 로고
    • Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation
    • Bagrodia S, Dérijard B, Davis RJ, Cerione RA: Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation. J Biol Chem 1995;270:27995-27998.
    • (1995) J Biol Chem , vol.270 , pp. 27995-27998
    • Bagrodia, S.1    Dérijard, B.2    Davis, R.J.3    Cerione, R.A.4
  • 69
    • 0029950672 scopus 로고    scopus 로고
    • Actions of Rho family small G proteins and p21-activated protein kinases on mitogen-activated protein kinase family members
    • Frost JA, Xu S, Hutchison MR, Marcus S, Cobb MH: Actions of Rho family small G proteins and p21-activated protein kinases on mitogen-activated protein kinase family members. Mol Cell Biol 1996;16:3707-3713.
    • (1996) Mol Cell Biol , vol.16 , pp. 3707-3713
    • Frost, J.A.1    Xu, S.2    Hutchison, M.R.3    Marcus, S.4    Cobb, M.H.5
  • 70
    • 0032579244 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase γ is a mediator of Gβγ- dependent Jun kinase activation
    • Lopez-Ilasaca M, Gutkind JS, Wetzker R: Phosphoinositide 3-kinase γ is a mediator of Gβγ-dependent Jun kinase activation. J Biol Chem 1998;273:2505-2508.
    • (1998) J Biol Chem , vol.273 , pp. 2505-2508
    • Lopez-Ilasaca, M.1    Gutkind, J.S.2    Wetzker, R.3
  • 71
    • 0033615694 scopus 로고    scopus 로고
    • Reciprocal signaling between heterotrimeric G proteins and the p21-stimulated protein kinase
    • Wang J, Frost JA, Cobb MH, Ross EM: Reciprocal signaling between heterotrimeric G proteins and the p21-stimulated protein kinase. J Biol Chem 1999;274:31641-31647.
    • (1999) J Biol Chem , vol.274 , pp. 31641-31647
    • Wang, J.1    Frost, J.A.2    Cobb, M.H.3    Ross, E.M.4
  • 73
    • 0032504964 scopus 로고    scopus 로고
    • The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity
    • Nikolic M, Chou MM, Lu W, Mayer BJ, Tsai LH: The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity. Nature 1998;395:194-198.
    • (1998) Nature , vol.395 , pp. 194-198
    • Nikolic, M.1    Chou, M.M.2    Lu, W.3    Mayer, B.J.4    Tsai, L.H.5
  • 74
    • 0035088897 scopus 로고    scopus 로고
    • Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction
    • Fu AK, Fu WY, Cheung J, Tsim KW, Ip FC, Wang JH, Ip NY: Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction. Nat Neurosci 2001;4:374-381.
    • (2001) Nat Neurosci , vol.4 , pp. 374-381
    • Fu, A.K.1    Fu, W.Y.2    Cheung, J.3    Tsim, K.W.4    Ip, F.C.5    Wang, J.H.6    Ip, N.Y.7
  • 75
    • 0035021950 scopus 로고    scopus 로고
    • ERK induces p35, a neuron-specific activator of Cdk5, through induction of Egr1
    • Harada T, Morooka T, Ogawa S, Nishida E: ERK induces p35, a neuron-specific activator of Cdk5, through induction of Egr1. Nat Cell Biol 2001;3:453-459.
    • (2001) Nat Cell Biol , vol.3 , pp. 453-459
    • Harada, T.1    Morooka, T.2    Ogawa, S.3    Nishida, E.4
  • 76
    • 0029943605 scopus 로고    scopus 로고
    • Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways
    • Klippel A, Reinhard C, Kavanaugh WM, Apell G, Escobedo M-A, Williams LT: Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways. Mol Cell Biol 1996;16:4117-4127.
    • (1996) Mol Cell Biol , vol.16 , pp. 4117-4127
    • Klippel, A.1    Reinhard, C.2    Kavanaugh, W.M.3    Apell, G.4    Escobedo, M.-A.5    Williams, L.T.6
  • 78
    • 33746537715 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase γ mediates shear stress-dependent activation of JNK in endothelial cells
    • Go YM, Park H, Maland MC, Darley-Usmar VM, Stoyanov B, Wetzker R, Jo H: Phosphatidylinositol 3-kinase γ mediates shear stress-dependent activation of JNK in endothelial cells. Am J Physiol 1998;275:H1898-H1904.
    • (1998) Am J Physiol , vol.275
    • Go, Y.M.1    Park, H.2    Maland, M.C.3    Darley-Usmar, V.M.4    Stoyanov, B.5    Wetzker, R.6    Jo, H.7
  • 79
    • 0033806918 scopus 로고    scopus 로고
    • The CB1 cannabinoid receptor is coupled to the activation of c-Jun terminal kinase
    • Rueda D, Galve-Roperh I, Haro A, Guzmán M: The CB1 cannabinoid receptor is coupled to the activation of c-Jun terminal kinase. Mol Pharmacol 2000;58:814-820.
    • (2000) Mol Pharmacol , vol.58 , pp. 814-820
    • Rueda, D.1    Galve-Roperh, I.2    Haro, A.3    Guzmán, M.4
  • 81
    • 0033559333 scopus 로고    scopus 로고
    • Regulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G-protein-linked muscarinic acetylcholine receptors
    • Wylie PG, Challiss RAJ, Blank JL: Regulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G-protein-linked muscarinic acetylcholine receptors. Biochem J 1999;338:619-628.
    • (1999) Biochem J , vol.338 , pp. 619-628
    • Wylie, P.G.1    Challiss, R.A.J.2    Blank, J.L.3
  • 83
    • 0028891905 scopus 로고
    • Angiotensin II stimulates calcium-dependent activation of c-Jun N-terminal kinase
    • Zohn IE, Yu H, Li X, Cox AD, Earp HS: Angiotensin II stimulates calcium-dependent activation of c-Jun N-terminal kinase. Mol Cell Biol 1995;15:6160-6168.
    • (1995) Mol Cell Biol , vol.15 , pp. 6160-6168
    • Zohn, I.E.1    Yu, H.2    Li, X.3    Cox, A.D.4    Earp, H.S.5
  • 84
    • 0032572534 scopus 로고    scopus 로고
    • Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine; a role in cardiac myocyte hypertrophy?
    • Clerk A, Michael A, Sugden PH: Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine; a role in cardiac myocyte hypertrophy? J Cell Biol 1998;142:523-535.
    • (1998) J Cell Biol , vol.142 , pp. 523-535
    • Clerk, A.1    Michael, A.2    Sugden, P.H.3
  • 85
    • 0032230247 scopus 로고    scopus 로고
    • Stimulation of Jun N-terminal kinase (JNK) by gonadotropin-releasing hormone in pituitary αT3-1 cell line is mediated by protein kinase C, c-Src, and CDC42
    • Levi NL, Hanoch T, Benard O, Rozenblat M, Harris D, Reiss N, Naor Z, Seger R: Stimulation of Jun N-terminal kinase (JNK) by gonadotropin-releasing hormone in pituitary αT3-1 cell line is mediated by protein kinase C, c-Src, and CDC42. Mol Endocrinol 1998;12:815-824.
    • (1998) Mol Endocrinol , vol.12 , pp. 815-824
    • Levi, N.L.1    Hanoch, T.2    Benard, O.3    Rozenblat, M.4    Harris, D.5    Reiss, N.6    Naor, Z.7    Seger, R.8
  • 86
    • 0029770721 scopus 로고    scopus 로고
    • Activation of Pyk2 by stress signals and coupling with JNK signaling pathway
    • Tokiwa G, Dikic I, Lev S, Schlessinger J: Activation of Pyk2 by stress signals and coupling with JNK signaling pathway. Science 1996;273:792-794.
    • (1996) Science , vol.273 , pp. 792-794
    • Tokiwa, G.1    Dikic, I.2    Lev, S.3    Schlessinger, J.4
  • 87
    • 0033527738 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-encoded G protein-coupled receptor activation of c-jun amino-terminal kinase/stress-activated protein kinase and Lyn kinase is mediated by related adhesion focal tyrosine kinase/proline-rich tyrosine kinase 2
    • Munshi N, Ganju RK, Avraham S, Mesri EA, Groopman JE: Kaposi's sarcoma-associated herpesvirus-encoded G protein-coupled receptor activation of c-jun amino-terminal kinase/stress-activated protein kinase and Lyn kinase is mediated by related adhesion focal tyrosine kinase/proline-rich tyrosine kinase 2. J Biol Chem 1999;274:31863-31867.
    • (1999) J Biol Chem , vol.274 , pp. 31863-31867
    • Munshi, N.1    Ganju, R.K.2    Avraham, S.3    Mesri, E.A.4    Groopman, J.E.5
  • 88
    • 0032725309 scopus 로고    scopus 로고
    • Divergent signaling pathways link focal adhesion kinase to mitogen-activated protein kinase cascades
    • Igishi T, Fukuhara S, Patel V, Katz B-Z, Yamada KM, Gutkind JS: Divergent signaling pathways link focal adhesion kinase to mitogen-activated protein kinase cascades. J Biol Chem 1999;274:30738-30746.
    • (1999) J Biol Chem , vol.274 , pp. 30738-30746
    • Igishi, T.1    Fukuhara, S.2    Patel, V.3    Katz, B.-Z.4    Yamada, K.M.5    Gutkind, J.S.6
  • 89
    • 0029913510 scopus 로고    scopus 로고
    • Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway
    • Teramoto H, Coso OA, Miyata H, Igishi T, Miki T, Gutkind JS: Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. J Biol Chem 1996;271:27225- 27228.
    • (1996) J Biol Chem , vol.271 , pp. 27225-27228
    • Teramoto, H.1    Coso, O.A.2    Miyata, H.3    Igishi, T.4    Miki, T.5    Gutkind, J.S.6
  • 90
    • 0032558834 scopus 로고    scopus 로고
    • 12 stimulates Bruton's tyrosine kinase and a rasGAP through a conserved PH/BM domain
    • 12 stimulates Bruton's tyrosine kinase and a rasGAP through a conserved PH/BM domain. Nature 1998;395:808-813.
    • (1998) Nature , vol.395 , pp. 808-813
    • Jiang, Y.1    Ma, W.2    Wan, Y.3    Kozasa, T.4    Hattori, S.5    Huang, X.Y.6
  • 96
    • 0034065499 scopus 로고    scopus 로고
    • Transcriptional responses to growth factor and G protein-coupled receptors in PC12 cells: Comparison of α 1-adrenergic receptor subtypes
    • Minneman KP, Lee D, Zhong H, Berts A, Abbott KL, Murphy TJ: Transcriptional responses to growth factor and G protein-coupled receptors in PC12 cells: Comparison of α 1-adrenergic receptor subtypes. J Neurochem 2000;74:2392-2400.
    • (2000) J Neurochem , vol.74 , pp. 2392-2400
    • Minneman, K.P.1    Lee, D.2    Zhong, H.3    Berts, A.4    Abbott, K.L.5    Murphy, T.J.6
  • 98
    • 0032511882 scopus 로고    scopus 로고
    • The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338
    • King AJ, Sun H, Diaz B, Barnard D, Miao W, Bagrodia S, Marshall MS: The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338. Nature 1998;396:180-183.
    • (1998) Nature , vol.396 , pp. 180-183
    • King, A.J.1    Sun, H.2    Diaz, B.3    Barnard, D.4    Miao, W.5    Bagrodia, S.6    Marshall, M.S.7
  • 99
    • 15144353776 scopus 로고    scopus 로고
    • Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav
    • Han J, Luby-Phelps K, Das B, Shu X, Mosteller RD, Krishna UM, Falck JR, White MA, Brock D: Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav. Science 1998;279:558-560.
    • (1998) Science , vol.279 , pp. 558-560
    • Han, J.1    Luby-Phelps, K.2    Das, B.3    Shu, X.4    Mosteller, R.D.5    Krishna, U.M.6    Falck, J.R.7    White, M.A.8    Brock, D.9
  • 101
    • 0030040750 scopus 로고    scopus 로고
    • Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes
    • Lang P, Gesbert F, Delespine-Carmagnat M, Stancou R, Pouchelet M, Bertoglio J: Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes. EMBO J 1996;15:510-519.
    • (1996) EMBO J , vol.15 , pp. 510-519
    • Lang, P.1    Gesbert, F.2    Delespine-Carmagnat, M.3    Stancou, R.4    Pouchelet, M.5    Bertoglio, J.6
  • 102
    • 0032977036 scopus 로고    scopus 로고
    • Rho as a mediator of G-protein-coupled receptor signaling
    • Seasholtz TM, Majumdar M, Heller Brown J: Rho as a mediator of G-protein-coupled receptor signaling. Mol Pharmacol 1999;55:949-956.
    • (1999) Mol Pharmacol , vol.55 , pp. 949-956
    • Seasholtz, T.M.1    Majumdar, M.2    Heller Brown, J.3
  • 106
    • 0033523803 scopus 로고    scopus 로고
    • i2 proteins of v-fms-induced proliferation and transformation via Src-kinase and STAT3
    • i2 proteins of v-fms-induced proliferation and transformation via Src-kinase and STAT3. Oncogene 1999;18:6335-6342.
    • (1999) Oncogene , vol.18 , pp. 6335-6342
    • Corre, I.1    Baumann, H.2    Hermouet, S.3
  • 107
    • 0035952638 scopus 로고    scopus 로고
    • G protein coupled receptor signaling through the Src and Stat3 pathway: Role in proliferation and transformation
    • Ram PT, Iyengar R: G protein coupled receptor signaling through the Src and Stat3 pathway: Role in proliferation and transformation. Oncogene 2001;20:1601-1606.
    • (2001) Oncogene , vol.20 , pp. 1601-1606
    • Ram, P.T.1    Iyengar, R.2
  • 108
    • 0028101084 scopus 로고
    • CNTF, FGF and NGF collaborate to drive the terminal differentiation of MAH cells into postmitotic neurons
    • Ip NY, Boulton TG, Li Y, Verdi JM, Birren SJ, Anderson DJ, Yancopoulos GD: CNTF, FGF and NGF collaborate to drive the terminal differentiation of MAH cells into postmitotic neurons. Neuron 1994;13:443-455.
    • (1994) Neuron , vol.13 , pp. 443-455
    • Ip, N.Y.1    Boulton, T.G.2    Li, Y.3    Verdi, J.M.4    Birren, S.J.5    Anderson, D.J.6    Yancopoulos, G.D.7
  • 109
    • 0025572744 scopus 로고
    • s mediates epidermal growth factor-elicited stimulation of rat cardiac adenylate cyclase
    • s mediates epidermal growth factor-elicited stimulation of rat cardiac adenylate cyclase. J Biol Chem 1990;265:21317-21322.
    • (1990) J Biol Chem , vol.265 , pp. 21317-21322
    • Nair, B.G.1    Parikh, B.2    Milligan, G.3    Patel, T.B.4
  • 112
  • 113
    • 0032869096 scopus 로고    scopus 로고
    • Identification of genes induced by neuregulin in cultured myotubes
    • Fu AK, Cheung WM, Ip FC, Ip NY: Identification of genes induced by neuregulin in cultured myotubes. Mol Cell Neurosci 1999;14: 241-253.
    • (1999) Mol Cell Neurosci , vol.14 , pp. 241-253
    • Fu, A.K.1    Cheung, W.M.2    Ip, F.C.3    Ip, N.Y.4


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