The effect of nociceptin on Ca2+ channel current and intracellular Ca2+ in the SH-SY5Y human neuroblastoma cell line

British Journal of Pharmacology

Volumn 118, Issue 2, 1996, Pages 205-207

  Connor, Mark ^a,b   Yeo, Alison ^a   Henderson, Graeme ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b University of Sydney   (Australia)

Author keywords

Calcium currents; Calcium release; Nociceptin; ORL1; Orphanin FQ; SH SY5Y cells

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; CARBACHOL; NALOXONE; NALTRINDOLE; NOCICEPTIN; OPIATE ANTAGONIST; OPIATE RECEPTOR; OPIATE RECEPTOR AFFECTING AGENT; PERTUSSIS TOXIN; BORDETELLA VIRULENCE FACTOR; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; ENZYME INHIBITOR; NARCOTIC ANTAGONIST; OPIATE PEPTIDE;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; PRIORITY JOURNAL; AMINO ACID SEQUENCE; CELL CULTURE; DRUG ANTAGONISM; DRUG POTENTIATION; METABOLISM; MOLECULAR GENETICS; NEUROBLASTOMA;

AMINO ACID SEQUENCE; CALCIUM; CALCIUM CHANNEL BLOCKERS; CARBACHOL; ENZYME INHIBITORS; HUMANS; MOLECULAR SEQUENCE DATA; NARCOTIC ANTAGONISTS; NEUROBLASTOMA; OPIOID PEPTIDES; PERTUSSIS TOXIN; RECEPTORS, OPIOID; TUMOR CELLS, CULTURED; VIRULENCE FACTORS, BORDETELLA;

EID: 0029665959     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15387.x     Document Type: Article

References (10)

1. 3-opioid receptors in the SH-SY5Y human neuroblastoma cell line. J. Neurochem., 65, 170-175.
2. CHILDERS, S.R. (1993). Opioid receptor-coupled second messenger systems. In Opioids I. ed, Herz, A. pp. 189-216. Berlin: Springer-Verlag.
3. 2+ in SH-SY5Y human neuroblastoma cells. Br. J. Pharmacol., 117, 333-340.
4. KENNEDY, C. & HENDERSON, G. (1992). Chronic exposure to morphine does not induce dependence at the level of the calcium channel current in human SH-SY5Y cells. Neuroscience, 49, 937-944.
5. 1 receptor. Nature, 377, 532-535.
6. MOLLEREAU, C., PARMENTIER, M., MAILLEUX, P., BUTOUR, J.-L., MOISAND, C., CHALON, P., CAPUT, D., VASSART, G. & MEUNIER, J.-C. (1994). ORL1, a novel member of the opioid receptor family. FEBS Lett., 341, 33-38.
7. NORTH, R.A. (1993). Opioid actions on membrane ion channels. In Opioids I. ed. Herz, A. pp. 773-798. Berlin: Springer-Verlag.
8. REINSCHEID, R.K., NOTHACKER, H.-P., BOURSON, A., ARDATI, A., HENNINGSEN, R.A., BUNZOW, J.R., GRANDY, D.K., LANGEN H., MONSMA, F.J. & CIVELLI, O. (1995). Orphanin FQ: a neuropeptide that activates an opioid like G protein-coupled receptor. Science, 270, 792-794.
9. SEWARD, E.P., HAMMOND, C. & HENDERSON, G. (1991). μ-Opioid receptor-mediated inhibition of the N-type calcium channel current. Proc. R. Soc. Lond. B., 244, 129-135.
10. 2+ currents by μ and δ opioid receptor activation in differentiated human neuroblastoma cells. Adv. Biosci., 75, 181-183.