Nociceptin (ORL-1) and μ-opioid receptors mediate mitogen-activated protein kinase activation in CHO cells through a G(i)-coupled signaling pathway: Evidence for distinct mechanisms of agonist-mediated desensitization

Journal of Neurochemistry

Volumn 71, Issue 3, 1998, Pages 1024-1033

  Hawes, Brian E ^a   Fried, Steven ^a   Yao, Xiaorui ^a   Weig, Blair ^a   Graziano, Michael P ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

G(i) G(o) protein; Mitogen activated protein kinase; Nociceptin; Pertussis toxin; Opioid receptors

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MU OPIATE RECEPTOR; NOCICEPTIN;

ANALGESIA; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DESENSITIZATION; ENZYME ACTIVATION; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECEPTOR OCCUPANCY; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0031815227     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.71031024.x     Document Type: Article

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