Nociceptin inhibits calcium channel currents in a subpopulation of small nociceptive trigeminal ganglion neurons in mouse

Journal of Physiology

Volumn 536, Issue 1, 2001, Pages 35-47

  Borgland, Stephanie L ^a   Connor, Mark ^a   Christie, MacDonald J ^a,b  

^a University of Sydney   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALCIUM CHANNEL; CAPSAICIN; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; MORPHINE; MU OPIATE RECEPTOR AGONIST; NOCICEPTIN; PLANT LECTIN; ISOLECTIN B4;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CELL ISOLATION; CELL POPULATION; CELL SIZE; CELL TYPE; CHEMOSENSITIVITY; CONTROLLED STUDY; LECTIN BINDING; MOUSE; NERVE CELL; NERVE CELL MEMBRANE POTENTIAL; NOCICEPTION; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; TRIGEMINUS GANGLION; ANIMAL TISSUE; BRAIN ELECTROPHYSIOLOGY; CELL SUBPOPULATION; FEMALE; MALE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRIGEMINUS NUCLEUS NERVE CELL;

ANALGESICS, OPIOID; ANIMALS; CALCIUM CHANNELS; CAPSAICIN; CELL SIZE; CELLS, CULTURED; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; FEMALE; GTP-BINDING PROTEINS; LECTINS; MALE; MICE; MICE, INBRED C57BL; MORPHINE; NEURONS, AFFERENT; NOCICEPTORS; OPIOID PEPTIDES; PATCH-CLAMP TECHNIQUES; TRIGEMINAL GANGLION; VASODILATOR AGENTS; VIRULENCE FACTORS, BORDETELLA;

EID: 0035476877     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.2001.t01-1-00035.x     Document Type: Article

References (50)

1. 2+ channel current in rat sensory neurons by a G-protein-independent mechanisms
2. Axotomy reduces the effect of analgesic opioids yet increases the effect of nociceptin on dorsal root ganglion neurons
3. 2+ currents in rat sensory neurons
4. Differential modulation of N-type α1B and P/Q-type α1A calcium channels by different G protein α subunit isoforms
5. Splicing of α1A subunit gene generates phenotypic variants of P- and Q-type calcium channels
6. Unaltered peripheral excitatory actions of nociceptin contrast with spinal inhibitory effects after carrageenan inflammation: An electrophysiological study in the rat
7. Capsaicin and carbon dioxide act by distinct mechanisms on sensory nerve terminals in the cat cornea
8. Cellular mechanisms of opioid tolerance: Studies in single brain neurons
9. 2+ channel currents of acutely dissociated rat periaqueductal grey neurons
10. Calcium channel gating and modulation by transmitters depend on cellular compartmentalization
11. Isolation and culture of rat sensory neurons having distinct sensory modalities
12. Nomenclature of voltage-gated calcium channels
13. Depression of glutamatergic transmission by nociceptin in the neonatal rat hemisected spinal cord preparation in vitro
14. Response of sensory units with unmyelinated fibres to mechanical, thermal and chemical stimulation of the cat's cornea
15. Nociceptin and neurotransmitter release in the periphery
16. A comparative study of thermal and pH sensitive transducers in sensory neurons in rats and mice
17. Immunocytochemical localization of the vanilloid receptor 1 (VR1): Relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites
18. Improved patch-clamp technique for high resolution current recordings from cell and cell-free membrane patches
19. 2+ channels by G-protein βγ subunits
20. Voltage-dependent modulation of N-type calcium channels by G-protein βγ subunits
21. Nociceptin/orphanin FQ-induced nociceptive responses through substance P release from peripheral nerve endings in mice
22. Postsynaptic potassium current induced by nociceptin in medullary dorsal horn neurons
23. o
24. Modulation of voltage-gated calcium channels by orphanin FQ in freshly dissociated hippocampal neurons
25. Nociceptin-like immunoreactivity in the rat dorsal horn and inhibition of substantia gelatinosa neurons
26. 2+ channels in rat sympathetic ganglion neurons
27. Nickel block of three cloned calcium channels: Low concentrations selectively block α1H
28. Modulation of excitatory synaptic transmission by nociceptin in superficial dorsal horn neurones of the neonatal rat spinal cord
29. Nociceptin inhibits excitatory but not inhibitory transmission in substantia gelatinosa neurons of the adult rat spinal cord
30. Dynorphin A decreases voltage-dependent calcium conductance of mouse dorsal root ganglion neurons
31. Molecular and functional diversity of a family of rat brain T-type calcium channels
32. Nociceptin/orphanin FQ and the opioid receptor-like ORL1 receptor
33. Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor
34. μ- and κ-Opioid receptors selectively reduce the same transient components of high-threshold calcium current in rat dorsal root ganglion sensory neurons
35. ORL1 a novel member of the opioid receptor family. Cloning, functional expression and localization
36. Localization of orphanin FQ (nociceptin) peptide and messenger RNA in the central nervous system of the rat
37. In vitro and in vivo pharmacological characterization of J-113397, a potent and selective non-peptidyl ORL1 receptor antagonist
38. Differential expression of membrane currents in dissociated mouse primary sensory neurons
39. Orphanin FQ: A neuropeptide that activates opioid like G protein-coupled receptor
40. 2+ currents, but spares a sustained current
41. 2+ currents by a μ-opioid in a defined subset of rat sensory neurons
42. State-dependent inactivation of α1G T-type calcium channel
43. Quantitative single cell RT-PCR demonstrates selective μ-receptor transcription underlying opioid analgesia
44. Isolectin B(4) positive and negative nociceptors are functionally distinct
45. Inhibition of calcium currents in rat colon sensory neurons by κ but not μ or δ opioids
46. Selective opioid inhibition of small nociceptive neurons
47. Orphanin FQ (nociceptin) modulates responses of trigeminal neurons evoked by excitatory amino acids and somatosensory stimuli and blocks the substance P-induced facilitation of N-methyl-D-aspartate-evoked responses
48. 2+ current triggers burst firing through an afterdepolarizing potential in an adult mammalian neuron
49. Nociceptin/Orphanin FQ in spinal nociceptive mechanisms under normal and pathological conditions
50. OFQ reverses the κ-opioid receptor mediated depression of calcium current in rat dorsal root ganglion neurons