Structure-activity studies of the Phe4 residue of nociceptin(1-13)-NH2: Identification of highly potent agonists of the nociceptin/orphanin FQ receptor

Journal of Medicinal Chemistry

Volumn 44, Issue 23, 2001, Pages 3956-3964

  Guerrini, R ^a   Calo G ^a   Bigoni, R ^a   Rizzi, D ^a   Rizzi, A ^a   Zucchini, M ^a   Varani, K ^a   Hashiba, E ^b   Lambert, D G ^b   Toth, G ^c   Borea, P A ^a   Salvadori, S ^a   Regoli, D ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b LEICESTER ROYAL INFIRMARY   (United Kingdom)

^c INSTITUTE OF BIOCHEMISTRY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; FORSKOLIN; NOCICEPTIN; NOCICEPTIN RECEPTOR; PHENYL GROUP;

ANIMAL CELL; ANIMAL TISSUE; AROMATIZATION; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; BRAIN MEMBRANE; DRUG CONFORMATION; DRUG POTENCY; DRUG RECEPTOR BINDING; MALE; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION; VAS DEFERENS;

ANIMALS; BRAIN; CHO CELLS; CRICETINAE; CYCLIC AMP; ELECTRIC STIMULATION; HUMANS; MALE; MICE; OPIOID PEPTIDES; PEPTIDE FRAGMENTS; PHENYLALANINE; RECEPTORS, OPIOID; STRUCTURE-ACTIVITY RELATIONSHIP; VAS DEFERENS;

EID: 0035829420     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010221v     Document Type: Article

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