Ligands for κ-opioid and ORL1 receptors identified from a conformationally constrained peptide combinatorial library

Journal of Biological Chemistry

Volumn 274, Issue 39, 1999, Pages 27513-27522

  Becker, Jérôme A J ^a   Wallace, Andrew ^b,c   Garzon, Aaron ^b,d   Ingallinella, Paolo ^b   Bianchi, Elisabetta ^b   Cortese, Riccardo ^b   Simonin, Frédéric ^a   Kieffer, Brigitte L ^a   Pessi, Antonello ^b  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b IRBM   (Italy)

^c QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^d PHARMOS LTD   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

4 [ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 HYDROXYBENZYL] N,N DIETHYLBENZAMIDE; BENZODIAZEPINE DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; ENADOLINE; ENKEPHALIN DERIVATIVE; KAPPA OPIATE RECEPTOR; N,N DIALLYLTYROSYL 2 METHYLALANYL 2 METHYLALANYLPHENYLALANYLLEUCINE; NALTRINDOLE; NOCICEPTIN; OPIATE RECEPTOR; PEPTIDE LIBRARY;

AGONIST; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL STRAIN COS1; CHO CELL; CONFORMATIONAL TRANSITION; DRUG DESIGN; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; SCREENING;

AMINO ACID SEQUENCE; ANIMALS; BINDING, COMPETITIVE; CHO CELLS; COS CELLS; CRICETINAE; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; KINETICS; LIGANDS; OLIGOPEPTIDES; PEPTIDE LIBRARY; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, OPIOID; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, KAPPA; RECEPTORS, OPIOID, MU; RECOMBINANT PROTEINS; SULFUR RADIOISOTOPES; TRANSFECTION;

EID: 0033600840     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.39.27513     Document Type: Article

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