Natural product guided compound library development

Current Medicinal Chemistry

Volumn 9, Issue 23, 2002, Pages 2129-2145

  Breinbauer, Rolf ^a   Manger, Michael ^a   Scheck, Michael ^a   Waldmann, Herbert ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

Author keywords

Combinatorial chemistry; Drug discovery; Lead optimisation; Natural products; Organic synthesis; Protein domains; Solid phase synthesis

Indexed keywords

ANTIINFECTIVE AGENT; BENZAMIDINE DERIVATIVE; BENZAZEPINE DERIVATIVE; BENZODIAZEPINE DERIVATIVE; BENZOPYRAN DERIVATIVE; CYCLOSPORIN; EPOTHILONE A; ERYTHROMYCIN; GENISTEIN; IMMUNOSUPPRESSIVE AGENT; INDOLACTAM V; INDOLACTAM V DERIVATIVE; INDOLE DERIVATIVE; MACROLIDE; NAKIJIQUINONE DERIVATIVE; NATURAL PRODUCT; OLOMOUCINE; PIPERIDINE DERIVATIVE; PROSTAGLANDIN DERIVATIVE; PROSTANOID; QUINONE DERIVATIVE; SARCODICTYIN A; SARCODICTYIN DERIVATIVE; TACROLIMUS; TELEOCIDIN; TERPENOID DERIVATIVE; TETRAZOLE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VANCOMYCIN; VANCOMYCIN DERIVATIVE; BIOLOGICAL FACTOR;

ANTIMICROBIAL ACTIVITY; ARTICLE; BIOCHEMISTRY; BIOINFORMATICS; COMBINATORIAL CHEMISTRY; COMBINATORIAL LIBRARY; CONTROLLED STUDY; DRUG DESIGN; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG SYNTHESIS; HUMAN; LIGAND BINDING; NONHUMAN; PROTEIN DOMAIN; PROTEIN STRUCTURE; SOLID; STRUCTURE ACTIVITY RELATION; BINDING SITE; CHEMISTRY; REVIEW; SYNTHESIS;

BINDING SITES; BIOLOGICAL FACTORS; COMBINATORIAL CHEMISTRY TECHNIQUES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036423173     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867023368773     Document Type: Article

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