-
1
-
-
0032561249
-
-
Collins, F. S.; Patrinos, A.; Jordan, E.; Chakravarti, A.; Gesteland, R.; Walters, L.; and the members of the DOE and NIH planning groups Science 1998, 282, 682-689.
-
(1998)
Science
, vol.282
, pp. 682-689
-
-
Collins, F.S.1
Patrinos, A.2
Jordan, E.3
Chakravarti, A.4
Gesteland, R.5
Walters, L.6
-
2
-
-
0344817409
-
-
accessed Jun
-
Schreiber Group Website. http://www-schreiber.chem.harvard.edu (accessed Jun 1999).
-
(1999)
-
-
-
5
-
-
0028360374
-
-
Brown, E. J.; Albers, M. W.; Shin, T. B.; Ichikawa, K.; Keith, C. T.; Lane, W. S.; Schreiber, S. L. Nature 1994, 369, 756-758.
-
(1994)
Nature
, vol.369
, pp. 756-758
-
-
Brown, E.J.1
Albers, M.W.2
Shin, T.B.3
Ichikawa, K.4
Keith, C.T.5
Lane, W.S.6
Schreiber, S.L.7
-
7
-
-
0029932598
-
-
Taunton, J.; Hassig, C. A.; Schreiber, S. L. Science 1996, 272, 408-411.
-
(1996)
Science
, vol.272
, pp. 408-411
-
-
Taunton, J.1
Hassig, C.A.2
Schreiber, S.L.3
-
8
-
-
0032578762
-
-
Tong, J. K.; Hassig, C. A.; Schnitzler, G. R.; Kingston, R. E.; Schreiber, S. L. Nature 1998, 395, 917-921.
-
(1998)
Nature
, vol.395
, pp. 917-921
-
-
Tong, J.K.1
Hassig, C.A.2
Schnitzler, G.R.3
Kingston, R.E.4
Schreiber, S.L.5
-
9
-
-
0030113284
-
-
Hung, D. T.; Chen, J.; Schreiber, S. L. Chem. Biol. 1996, 3, 287-293.
-
(1996)
Chem. Biol.
, vol.3
, pp. 287-293
-
-
Hung, D.T.1
Chen, J.2
Schreiber, S.L.3
-
14
-
-
0025893762
-
-
Furka, A.; Sebestyén, F.; Asgedom, M.; Dibó, G. Int. J. Pept. Protein Res. 1991, 37, 487-493.
-
(1991)
Int. J. Pept. Protein Res.
, vol.37
, pp. 487-493
-
-
Furka, A.1
Sebestyén, F.2
Asgedom, M.3
Dibó, G.4
-
15
-
-
0026419328
-
-
Lam, K. S.; Salmon, S. E.; Hersh, E. M.; Hruby, V. J.; Kazmierski, W. M.; Knapp, R. J. Nature 1991, 354, 82-84.
-
(1991)
Nature
, vol.354
, pp. 82-84
-
-
Lam, K.S.1
Salmon, S.E.2
Hersh, E.M.3
Hruby, V.J.4
Kazmierski, W.M.5
Knapp, R.J.6
-
16
-
-
0033080348
-
-
Stockwell, B. R.; Haggarty, S. J.; Schreiber, S. L. Chem. Biol. 1999, 6, 71-83.
-
(1999)
Chem. Biol.
, vol.6
, pp. 71-83
-
-
Stockwell, B.R.1
Haggarty, S.J.2
Schreiber, S.L.3
-
17
-
-
0345248503
-
-
In press
-
Mayer, T. U.; Kapoor, T. M.; Haggarty, S. J.; King, R. W.; Schreiber, S. L.; Mitchison, T. J. Science. In press.
-
Science
-
-
Mayer, T.U.1
Kapoor, T.M.2
Haggarty, S.J.3
King, R.W.4
Schreiber, S.L.5
Mitchison, T.J.6
-
18
-
-
0033199751
-
-
MacBeath, G.; Koehler, A. N.; Schreiber, S. L. J. Am. Chem. Soc. 1999, 121, 7967-7968.
-
(1999)
J. Am. Chem. Soc.
, vol.121
, pp. 7967-7968
-
-
MacBeath, G.1
Koehler, A.N.2
Schreiber, S.L.3
-
19
-
-
0027362628
-
-
Ohlmeyer, M. H. J.; Swanson, R. N.; Dillard, L. W.; Reader, J. C.; Asouline, G.; Kobayashi, R.; Wigler, M.; Still, W. C. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 10922-10926.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 10922-10926
-
-
Ohlmeyer, M.H.J.1
Swanson, R.N.2
Dillard, L.W.3
Reader, J.C.4
Asouline, G.5
Kobayashi, R.6
Wigler, M.7
Still, W.C.8
-
20
-
-
0032569205
-
-
Tan, D. S.; Foley, M. A.; Shair, M. D.; Schreiber, S. L. J. Am. Chem. Soc. 1998, 120, 8565-8566.
-
(1998)
J. Am. Chem. Soc.
, vol.120
, pp. 8565-8566
-
-
Tan, D.S.1
Foley, M.A.2
Shair, M.D.3
Schreiber, S.L.4
-
21
-
-
0031549105
-
-
Bartlett and co-workers have proposed related criteria for the synthetic design of split-pool libraries: Marx, M. A.; Grillot, A.-L.; Louer, C. T.; Beaver, K. A.; Bartlett, P. A. J. Am. Chem. Soc. 1997, 119, 6153-6167.
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 6153-6167
-
-
Marx, M.A.1
Grillot, A.-L.2
Louer, C.T.3
Beaver, K.A.4
Bartlett, P.A.5
-
22
-
-
0344385650
-
-
accessed Jun
-
Rapp Polymere Home Page. http://www.rapp-polymere.com (accessed Jun 1999).
-
(1999)
-
-
-
23
-
-
0029361783
-
-
Brown, B. B.; Wagner, D. S.; Geysen, H. M. Mol. Div. 1995, 1, 4-12.
-
(1995)
Mol. Div.
, vol.1
, pp. 4-12
-
-
Brown, B.B.1
Wagner, D.S.2
Geysen, H.M.3
-
25
-
-
0031472576
-
-
You, A. J.; Jackman, R. J.; Whitesides, G. M.; Schreiber, S. L. Chem. Biol. 1997, 4, 969-975.
-
(1997)
Chem. Biol.
, vol.4
, pp. 969-975
-
-
You, A.J.1
Jackman, R.J.2
Whitesides, G.M.3
Schreiber, S.L.4
-
26
-
-
0031444011
-
-
Borchardt, A.; Liberles, S. D.; Biggar, S. R.; Crabtree, G. R.; Schreiber, S. L. Chem. Biol. 1997, 4, 961-968.
-
(1997)
Chem. Biol.
, vol.4
, pp. 961-968
-
-
Borchardt, A.1
Liberles, S.D.2
Biggar, S.R.3
Crabtree, G.R.4
Schreiber, S.L.5
-
27
-
-
0028853358
-
-
Tamura, O.; Okabe, T.; Yamaguchi, T.; Gotanda, K.; Noe, K.; Sakamoto, M. Tetrahedron 1995, 51, 107-118.
-
(1995)
Tetrahedron
, vol.51
, pp. 107-118
-
-
Tamura, O.1
Okabe, T.2
Yamaguchi, T.3
Gotanda, K.4
Noe, K.5
Sakamoto, M.6
-
28
-
-
0028890335
-
-
Tamura, O.; Okabe, T.; Yamaguchi, T.; Kotani, J.; Gotanda, K.; Sakamoto, M. Tetrahedron 1995, 51, 119-128.
-
(1995)
Tetrahedron
, vol.51
, pp. 119-128
-
-
Tamura, O.1
Okabe, T.2
Yamaguchi, T.3
Kotani, J.4
Gotanda, K.5
Sakamoto, M.6
-
29
-
-
0345248492
-
-
note
-
Tamura et al. propose reaction of the Z-nitrone via an exo transition state. However, orbital overlap appears to be more favorable in the reaction of the E-nitrone via an endo transition state as indicated in Scheme 1.
-
-
-
-
33
-
-
0345248490
-
-
note
-
All resin-bound products were photocleaved and analyzed by standard techniques (TLC, HPLC, NMR, MS).
-
-
-
-
34
-
-
33751500481
-
-
Otera, J.; Dan-oh, N.; Nozaki, H. J. Org. Chem. 1991, 56, 5307-5311.
-
(1991)
J. Org. Chem.
, vol.56
, pp. 5307-5311
-
-
Otera, J.1
Dan-oh, N.2
Nozaki, H.3
-
36
-
-
0345248489
-
-
note
-
Abbreviations not cited in text: DMF = N,N-dimethylformamide, DMA = N,N-dimethylacetamide, NMP = N-methylpyrrolidinone, PyBroP = bromotripyrrolidinophosphonium hexafluorophosphate, HATU = N-[(dimethylamino)-1H-1,2,3-triazolo[4,5-b]pyridin-1-ylmethylene]-N- methylmethan-aminium hexafluorophosphate, PyBOP = benzotriazol-1-yloxytripyrroli-dinophosphonium hexafluorophosphate, TFFH = N,N,N′,N′-tetramethylfluoroformamidinium hexafluorophosphate, DIPC = 1,3-diisopropylcarbodiimide, CDI = 1,1′-carbonyldiimidazole, DIPEA = N,N-diisopropylethylamine, DMAP = 4-(dimethylamino)pyridine, cod = 1,5-cyclooctadiene, DPPF = 1,1′-bis(diphenylphosphino)ferrocene, DBN = 1,5-diazabicyclo[4.3.0]non-5-ene, LC-MS = tandem high-pressure liquid chromatography-mass spectrometry, HR-FAB-MS = high-resolution fast atom bombardment mass spectrometry, HR-TOF-ESI-MS = high-resolution time-of-flight electrospray induction mass spectrometry, EC-GC = electron capture detection gas chromatography.
-
-
-
-
37
-
-
0345680152
-
-
note
-
The term "building block" is preferred over the commonly used term "monomer" since the products are non-oligomeric.
-
-
-
-
38
-
-
37049083984
-
-
Meguro, M.; Asao, N.; Yamamoto, Y. J. Chem. Soc., Perkin Trans. 1 1994, 2597-2601.
-
(1994)
J. Chem. Soc., Perkin Trans. 1
, pp. 2597-2601
-
-
Meguro, M.1
Asao, N.2
Yamamoto, Y.3
-
40
-
-
37049126859
-
-
Lindsay Smith, J. R.; Norman, R. O. C.; Stillings, M. R. J. Chem. Soc., Perkin Trans. 1 1975, 1200-1202.
-
(1975)
J. Chem. Soc., Perkin Trans. 1
, pp. 1200-1202
-
-
Lindsay Smith, J.R.1
Norman, R.O.C.2
Stillings, M.R.3
-
42
-
-
4043071644
-
-
Borch, R. F.; Bernstein, M. D.; Durst, H. D. J. Am. Chem. Soc. 1971, 93, 2897-2904.
-
(1971)
J. Am. Chem. Soc.
, vol.93
, pp. 2897-2904
-
-
Borch, R.F.1
Bernstein, M.D.2
Durst, H.D.3
-
49
-
-
0001644755
-
-
Guiles, J. W.; Johnson, S. G.; Murray, W. V. J. Org. Chem. 1996, 61, 5169-5171.
-
(1996)
J. Org. Chem.
, vol.61
, pp. 5169-5171
-
-
Guiles, J.W.1
Johnson, S.G.2
Murray, W.V.3
-
52
-
-
0000723539
-
-
Young, J. K.; Nelson, J. C.; Moore, J. S. J. Am. Chem. Soc. 1994, 116, 10841-10842.
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 10841-10842
-
-
Young, J.K.1
Nelson, J.C.2
Moore, J.S.3
-
54
-
-
0004138846
-
-
San Francisco, CA, April ORGN 574
-
Odingo, J.; Sharpe, B. A.; Oare, D. Presented at the 213th National Meeting of the American Chemical Society, San Francisco, CA, April 1997; ORGN 574.
-
(1997)
213th National Meeting of the American Chemical Society
-
-
Odingo, J.1
Sharpe, B.A.2
Oare, D.3
-
55
-
-
0000633011
-
-
Trost, B. M., Fleming, I., Eds.; Permangon Press: Oxford
-
Heck, R. F. In Comprehensive Organic Synthesis; Trost, B. M., Fleming, I., Eds.; Permangon Press: Oxford, 1991; Vol. 4, pp 833-863.
-
(1991)
Comprehensive Organic Synthesis
, vol.4
, pp. 833-863
-
-
Heck, R.F.1
-
56
-
-
0029030381
-
-
Hiroshige, M.; Hauske, J. R.; Zhou, P. Tetrahedron Lett. 1995, 36, 4567-4570.
-
(1995)
Tetrahedron Lett.
, vol.36
, pp. 4567-4570
-
-
Hiroshige, M.1
Hauske, J.R.2
Zhou, P.3
-
57
-
-
0001038733
-
-
Wolfe, J. P.; Wagaw, S.; Marcoux, J.-F.; Buchwald, S. L. Acc. Chem. Res. 1998, 31, 805-818.
-
(1998)
Acc. Chem. Res.
, vol.31
, pp. 805-818
-
-
Wolfe, J.P.1
Wagaw, S.2
Marcoux, J.-F.3
Buchwald, S.L.4
-
60
-
-
0344385618
-
-
note
-
3-Bn, 69% side reaction; R = 4-I-Bn, 59%; R = 4-Cl-Bn, 32%; R = Bn, 24%; R = 4-tBu-Bn, 13%; R = 3-I-Bn, 46%; R = 2-I-Bn, 31%.) Replacement of the ω-aminocaproic acid spacer with glycine or removal of the spacer altogether actually decreases the amount of 10 formed. (For 12, R = 4-I-Bn: Aca spacer, 59% side reaction; Gly spacer, 36%; no spacer 29%.) Interestingly, substitution at the benzylic carbon eliminates the side reaction altogether (for 12, R = 4-I-α-Me-Bn, 0% side reaction). Moreover, solution-phase aminolysis of the tetracycle below results in no side reaction. Control experiments verified that the side reaction is not caused by photocleavage. (illustration presented)
-
-
-
-
61
-
-
0345680137
-
-
note
-
Aminolysis in the presence of sodium cyanide in MeOH, sodium hydride in DMA, sodium methoxide in benzene, ferric chloride in MeOH, lithium chloride in MeOH, and lithium hydroxide in MeOH all appeared to result in degradation of the linker. Aminolysis in the presence of the Otera organotin catalyst in toluene did not reduce the amount of epoxycyclohexenol recovered.
-
-
-
-
66
-
-
0017360671
-
-
Olofson, R. A.; Schnur, R. C.; Bunes, L.; Pepe, J. P. Tetrahedron Lett. 1977, 1567-1570.
-
(1977)
Tetrahedron Lett.
, pp. 1567-1570
-
-
Olofson, R.A.1
Schnur, R.C.2
Bunes, L.3
Pepe, J.P.4
-
67
-
-
0021260262
-
-
Olofson, R. A.; Martz, J. T.; Senet, J.-P.; Piteau, M.; Malfroot, T. J. Org. Chem. 1984, 49, 2081-2082.
-
(1984)
J. Org. Chem.
, vol.49
, pp. 2081-2082
-
-
Olofson, R.A.1
Martz, J.T.2
Senet, J.-P.3
Piteau, M.4
Malfroot, T.5
-
70
-
-
0001391308
-
-
Wiley & Sons: New York, Collect.
-
Kamm, O. Organic Syntheses; Wiley & Sons: New York, 1941; Collect. Vol. I, pp 445-447.
-
(1941)
Organic Syntheses
, vol.1
, pp. 445-447
-
-
Kamm, O.1
-
71
-
-
0344817352
-
-
note
-
2; and (7) esterification with the Otera organotin catalyst.
-
-
-
-
72
-
-
0345680135
-
-
note
-
Despite considerable efforts to understand this vexing side reaction, both its exact mechanism and a rationalization of the ameliorating effects of alkynylbenzyl substituents remain mysterious to us.
-
-
-
-
75
-
-
0027202613
-
-
Hobbs DeWitt, S.; Kiely, J. S.; Stankovic, C. J.; Schroeder, M. C; Reynolds Cody, D. M.; Pavia, M. R. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 6909-6913.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 6909-6913
-
-
Hobbs DeWitt, S.1
Kiely, J.S.2
Stankovic, C.J.3
Schroeder, M.C.4
Reynolds Cody, D.M.5
Pavia, M.R.6
-
77
-
-
0030474630
-
-
Kurth, M. J.; Ahlberg Randall, L. A.; Takenouchi, K. J. Org. Chem. 1996, 61, 8755-8761.
-
(1996)
J. Org. Chem.
, vol.61
, pp. 8755-8761
-
-
Kurth, M.J.1
Ahlberg Randall, L.A.2
Takenouchi, K.3
-
78
-
-
0000694272
-
-
Beebe, X.; Schore, N. E.; Kurth, M. J. J. Org. Chem. 1995, 60, 4196-4203.
-
(1995)
J. Org. Chem.
, vol.60
, pp. 4196-4203
-
-
Beebe, X.1
Schore, N.E.2
Kurth, M.J.3
-
79
-
-
0027104788
-
-
Beebe, X.; Schore, N. E.; Kurth, M. J. J. Am. Chem. Soc. 1992, 114, 10061-10062.
-
(1992)
J. Am. Chem. Soc.
, vol.114
, pp. 10061-10062
-
-
Beebe, X.1
Schore, N.E.2
Kurth, M.J.3
-
80
-
-
0029361890
-
-
Meyers, H. V.; Dilley, G. J.; Durgin, T. L.; Powers, T. S.; Winssinger, N. A.; Zhu, H.; Pavia, M. R. Mol. Div. 1995, 1, 13-20.
-
(1995)
Mol. Div.
, vol.1
, pp. 13-20
-
-
Meyers, H.V.1
Dilley, G.J.2
Durgin, T.L.3
Powers, T.S.4
Winssinger, N.A.5
Zhu, H.6
Pavia, M.R.7
-
81
-
-
0000099596
-
-
Kokubo, K.; Matsumasa, K.; Miura, M.; Nomura, M. J. Org. Chem. 1997, 62, 4564-4565.
-
(1997)
J. Org. Chem.
, vol.62
, pp. 4564-4565
-
-
Kokubo, K.1
Matsumasa, K.2
Miura, M.3
Nomura, M.4
-
82
-
-
0345248472
-
-
The 1996-1997 Aldrich Structure Index lists 24 applicable salicyl aldehydes
-
The 1996-1997 Aldrich Structure Index lists 24 applicable salicyl aldehydes.
-
-
-
-
83
-
-
0345248471
-
-
note
-
The 1996-1997 Aldrich Structure Index lists 54 applicable symmetrical anhydrides compared to over 1000 carboxylic acids.
-
-
-
-
85
-
-
0030182486
-
-
Atuegbu, A.; Maclean, D.; Nguyen, C.; Gordon, E. M.; Jacobs, J. W. Bioorg. Med. Chem. 1996, 4, 1097-1106.
-
(1996)
Bioorg. Med. Chem.
, vol.4
, pp. 1097-1106
-
-
Atuegbu, A.1
Maclean, D.2
Nguyen, C.3
Gordon, E.M.4
Jacobs, J.W.5
-
86
-
-
0344817348
-
-
Certain acid-sensitive products were also analyzed by TLC and FABMS
-
Certain acid-sensitive products were also analyzed by TLC and FABMS.
-
-
-
-
87
-
-
0030062879
-
-
Combs, A. P.; Kapoor, T. M.; Feng, S.; Chen, J. K.; Daudé-Snow, L. F.; Schreiber, S. L. J. Am. Chem. Soc. 1996, 118, 287-288.
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 287-288
-
-
Combs, A.P.1
Kapoor, T.M.2
Feng, S.3
Chen, J.K.4
Daudé-Snow, L.F.5
Schreiber, S.L.6
-
88
-
-
0345248470
-
-
note
-
n = X, where X represents all eight building blocks at a given position.
-
-
-
-
90
-
-
0029036168
-
-
Burbaum, J. J.; Ohlemeyer, M. H. J.; Reader, J. C.; Henderson, L; Dillard, L. W.; Li, G.; Randle, T. L.; Sigal, N. H.; Chelsky, D.; Baldwin, J. J. Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 6027-6031.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 6027-6031
-
-
Burbaum, J.J.1
Ohlemeyer, M.H.J.2
Reader, J.C.3
Henderson, L.4
Dillard, L.W.5
Li, G.6
Randle, T.L.7
Sigal, N.H.8
Chelsky, D.9
Baldwin, J.J.10
-
91
-
-
0029013332
-
-
Baldwin, J. J., Burbaum, J. J.; Henderson, I.; Ohlemeyer, M. H. J. J. Am. Chem. Soc. 1995, 117, 5588-5589.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 5588-5589
-
-
Baldwin, J.J.1
Burbaum, J.J.2
Henderson, I.3
Ohlemeyer, M.H.J.4
-
92
-
-
0032515410
-
-
Kapoor, T. M.; Hamilton Andreotti, A.; Schreiber, S. L. J. Am. Chem. Soc. 1998, 120, 23-29.
-
(1998)
J. Am. Chem. Soc.
, vol.120
, pp. 23-29
-
-
Kapoor, T.M.1
Hamilton Andreotti, A.2
Schreiber, S.L.3
-
93
-
-
0032515399
-
-
Morken, J. P.; Kapoor, T. M.; Feng, S.; Shirai, F.; Schreiber, S. L. J. Am. Chem. Soc. 1998, 120, 30-36.
-
(1998)
J. Am. Chem. Soc.
, vol.120
, pp. 30-36
-
-
Morken, J.P.1
Kapoor, T.M.2
Feng, S.3
Shirai, F.4
Schreiber, S.L.5
-
94
-
-
0030915475
-
-
Maclean, D.; Schullek, J. R.; Murphy, M. M.; Ni, Z.-J.; Gordon, E. M.; Gallop, M. A. Proc. Natl. Acad. Sci. U.S.A. 1997, 94, 2805-2810.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 2805-2810
-
-
Maclean, D.1
Schullek, J.R.2
Murphy, M.M.3
Ni, Z.-J.4
Gordon, E.M.5
Gallop, M.A.6
-
95
-
-
10544229790
-
-
Liang, R.; Yan, L.; Loebach, J.; Ge, M.; Uozumi, Y.; Sekanina, K.; Horan, N.; Gildersleeve, J.; Thompson, C.; Smith, A.; Biswas, K.; Still, W. C.; Kahne, D. Science 1996, 274, 1520-1522.
-
(1996)
Science
, vol.274
, pp. 1520-1522
-
-
Liang, R.1
Yan, L.2
Loebach, J.3
Ge, M.4
Uozumi, Y.5
Sekanina, K.6
Horan, N.7
Gildersleeve, J.8
Thompson, C.9
Smith, A.10
Biswas, K.11
Still, W.C.12
Kahne, D.13
-
96
-
-
0031106616
-
-
Schullek, J. R.; Butler, J. H.; Ni, Z.-J.; Chen, D.; Yuan, Z. Anal. Biochem. 1997, 246, 20-29.
-
(1997)
Z. Anal. Biochem.
, vol.246
, pp. 20-29
-
-
Schullek, J.R.1
Butler, J.H.2
Ni, Z.-J.3
Chen, D.4
Yuan5
-
97
-
-
0032542040
-
-
Dilanni Carroll, C.; Johnson, T. O.; Tao, S.; Lauri, G.; Orlowski, M.; Gluzman, I. Y.; Goldberg, D. E.; Dolle, R. E. Bioorg. Med. Chem. Lett. 1998, 8, 3203-3206.
-
(1998)
Bioorg. Med. Chem. Lett.
, vol.8
, pp. 3203-3206
-
-
Dilanni Carroll, C.1
Johnson, T.O.2
Tao, S.3
Lauri, G.4
Orlowski, M.5
Gluzman, I.Y.6
Goldberg, D.E.7
Dolle, R.E.8
-
98
-
-
33751157590
-
-
Nestler, H. P.; Bartlett, P. A.; Still, W. C. J. Org. Chem. 1994, 59, 4723-4724.
-
(1994)
J. Org. Chem.
, vol.59
, pp. 4723-4724
-
-
Nestler, H.P.1
Bartlett, P.A.2
Still, W.C.3
-
100
-
-
0344817315
-
-
FACS Screening Web Page, accessed Jun
-
Nolan, G. P., FACS Screening Web Page, http://www.stanford.edu/ group/nolan/FACSscrn.html (accessed Jun 1999).
-
(1999)
-
-
Nolan, G.P.1
-
101
-
-
0345248427
-
-
Based upon previous results, a 50% yield was assumed
-
Based upon previous results, a 50% yield was assumed.
-
-
-
-
102
-
-
0344385577
-
-
The rapamycin concentration was 100 nM. J. Huang and S. L. S., unpublished results
-
The rapamycin concentration was 100 nM. J. Huang and S. L. S., unpublished results.
-
-
-
-
103
-
-
0345248426
-
-
unpublished results
-
R. W. King, unpublished results.
-
-
-
King, R.W.1
-
104
-
-
0028894025
-
-
Carcamo, J.; Zemella, A.; Massague, J. Mol. Cell. Biol. 1995, 15, 1573-1581.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 1573-1581
-
-
Carcamo, J.1
Zemella, A.2
Massague, J.3
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