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Volumn 3, Issue 3, 2001, Pages 301-311

Solid-phase synthesis of macrolide analogues

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; CETHROMYCIN; CLARITHROMYCIN; DRUG DERIVATIVE; ERYTHROMYCIN; KETOLIDE; MACROLIDE; NINHYDRIN;

EID: 0035348720     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc0100013     Document Type: Article
Times cited : (24)

References (13)
  • 3
    • 0001616880 scopus 로고
    • The structure and stereochemistry of erythromycin A
    • Harris, D. R.; McGeachin, S. G.; Mills, H. H. The Structure and Stereochemistry of Erythromycin A. Tetrahedron Lett. 1965, 11, 679-685.
    • (1965) Tetrahedron Lett. , vol.11 , pp. 679-685
    • Harris, D.R.1    McGeachin, S.G.2    Mills, H.H.3
  • 4
    • 0011484697 scopus 로고
    • Synthetic modifications of the erythromycin a macrolactone: Effects on biological activity
    • Rahman, A., Ed.; Elsevier Science Publishers B. V: Amsterdam
    • Latrey, P. A.; Perun, T. J. Synthetic Modifications of the Erythromycin A Macrolactone: Effects on Biological Activity. In Studies in Natural Products Chemistry; Rahman, A., Ed.; Elsevier Science Publishers B. V: Amsterdam, 1993; Vol. 13, pp 155-185.
    • (1993) Studies in Natural Products Chemistry , vol.13 , pp. 155-185
    • Latrey, P.A.1    Perun, T.J.2
  • 5
    • 0032759821 scopus 로고    scopus 로고
    • Recent progress in novel macrolides, quinolones and 2-pyridones to overcome bacterial resistance
    • Chu, D. T. W.; Recent Progress in Novel Macrolides, Quinolones and 2-Pyridones to Overcome Bacterial Resistance. Med. Res. Rev. 1999, 19, 497-520.
    • (1999) Med. Res. Rev. , vol.19 , pp. 497-520
    • Chu, D.T.W.1
  • 6
    • 0000184017 scopus 로고    scopus 로고
    • Design, synthesis, and antimicrobial activity of 6-o-substituted ketolides active against resistant respiratory track pathogens
    • Or, Y. S.; Clark, R. F.; Wang, S.; Chu, D. T. W.; Nilius, A. M.; Flamm, R. K.; Mitten, M.; Ewing, P.; Alder, J.; Ma, Z. Design, Synthesis, and Antimicrobial Activity of 6-O-Substituted Ketolides Active against Resistant Respiratory Track Pathogens. J. Med. Chem. 2000, 43, 1045-1049.
    • (2000) J. Med. Chem. , vol.43 , pp. 1045-1049
    • Or, Y.S.1    Clark, R.F.2    Wang, S.3    Chu, D.T.W.4    Nilius, A.M.5    Flamm, R.K.6    Mitten, M.7    Ewing, P.8    Alder, J.9    Ma, Z.10
  • 8
    • 0042327458 scopus 로고    scopus 로고
    • note
    • 3-Keto analogues are known to exhibit better antibacterial profiles than 3-OH analogues.
  • 9
    • 0041325965 scopus 로고    scopus 로고
    • For experimental details, see ref 6
    • For experimental details, see ref 6.
  • 10
    • 0023901653 scopus 로고
    • Modifications of macrolide antibiotics. Synthesis of 11-deoxy-11-(carboxyamino)-6-o-methylerythromycin A 11,12-(cyclic esters) via intramolecular Michael reaction of O-carbamates with an α,β-unsaturated ketone
    • Baker, W. R.; Clark, J. D.; Stephens, R. L.; Kim, K. H. Modifications of macrolide antibiotics. Synthesis of 11-deoxy-11-(carboxyamino)-6-O-methylerythromycin A 11,12-(cyclic esters) via intramolecular Michael reaction of O-carbamates with an α,β-unsaturated ketone. J. Org. Chem. 1988, 53, 2340-2345.
    • (1988) J. Org. Chem. , vol.53 , pp. 2340-2345
    • Baker, W.R.1    Clark, J.D.2    Stephens, R.L.3    Kim, K.H.4
  • 12
    • 0000495922 scopus 로고    scopus 로고
    • Encoding of combinatorial chemistry libraries by fluorine-19 NMR
    • Hochlowski, J. E.; Whittern, D. N.; Sowin, T. J. Encoding of Combinatorial Chemistry Libraries by Fluorine-19 NMR. J. Comb. Chem. 1999, 1, 291-293.
    • (1999) J. Comb. Chem. , vol.1 , pp. 291-293
    • Hochlowski, J.E.1    Whittern, D.N.2    Sowin, T.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.