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Angewandte Chemie - International Edition

Volumn 41, Issue 16, 2002, Pages 2878-2890

From protein domains to drug candidates - Natural products as guiding principles in the design and synthesis of compound libraries

(3) Breinbauer, Rolf a,b Vetter, Ingrid R a Waldmann, Herbert a,b

a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY (Germany)

b TU DORTMUND UNIVERSITY (Germany)

Author keywords

Bioorganic chemistry; Combinatorial chemistry; Natural products; Protein structures; Solid phase synthesis

Indexed keywords

DRUG PRODUCTS; MOLECULAR STRUCTURE; PROBABILITY; SYNTHESIS (CHEMICAL);

BIOINFORMATICS; COMPOUND LIBRARIES;

PROTEINS;

ANTINEOPLASTIC AGENT; DYSIDIOLIDE; EPOTHILONE A; INDOLACTAM V; NATURAL PRODUCT; NUCLEOTIDE DERIVATIVE; SARCODICTYIN A; BIOLOGICAL FACTOR; GUANOSINE TRIPHOSPHATE; PEPTIDE; PEPTIDE LIBRARY; PROTEIN;

COMBINATORIAL CHEMISTRY; DRUG DESIGN; DRUG SYNTHESIS; LIBRARY; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN STRUCTURE; REVIEW; STRUCTURE ANALYSIS; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; PROTEIN SECONDARY STRUCTURE; SYNTHESIS;

BINDING SITES; BIOLOGICAL FACTORS; DRUG DESIGN; GUANOSINE TRIPHOSPHATE; MODELS, MOLECULAR; PEPTIDE LIBRARY; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; PROTEINS;

EID: 0037119336 PISSN: 14337851 EISSN: None Source Type: Journal
DOI: 10.1002/1521-3773(20020816)41:16<2878::AID-ANIE2878>3.0.CO;2-B Document Type: Review

Times cited : (441)

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