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Volumn 41, Issue 18, 1998, Pages 3325-3329

A scoring scheme for discriminating between drugs and nondrugs

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; AMOXICILLIN PLUS CLAVULANIC ACID; CAPTOPRIL; CIPROFLOXACIN; DICLOFENAC; DILTIAZEM; DRUG; ENALAPRIL; FLUOXETINE; NIFEDIPINE; RANITIDINE; SIMVASTATIN;

EID: 0032572816     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9706776     Document Type: Article
Times cited : (433)

References (10)
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    • Warr, W. A. Combinatorial Chemistry and Molecular Diversity. An Overview. J. Chem. Inf. Comput. Sci. 1997, 37, 134-140.
    • (1997) J. Chem. Inf. Comput. Sci. , vol.37 , pp. 134-140
    • Warr, W.A.1
  • 2
    • 0030756360 scopus 로고    scopus 로고
    • Reactive compounds and in vitro false positives in HTS
    • Rishton, G. M. Reactive compounds and in vitro false positives in HTS. Drug Discovery Today 1997, 2, 382-384.
    • (1997) Drug Discovery Today , vol.2 , pp. 382-384
    • Rishton, G.M.1
  • 3
    • 84889141812 scopus 로고    scopus 로고
    • Development of Bioactivity Profiles for Use in Compound Selection
    • March 24-28, CINF 066
    • Gillet, V. J.; Willett, P.; Bradshaw, J. Development of Bioactivity Profiles for Use in Compound Selection. 211th ACS National Meeting, March 24-28, 1996, CINF 066.
    • (1996) 211th ACS National Meeting
    • Gillet, V.J.1    Willett, P.2    Bradshaw, J.3
  • 6
    • 15444353154 scopus 로고    scopus 로고
    • note
    • The following rules for removing unsuited compounds were applied: Molecular weight less than 150 or greater than 1000. Metal-containing compounds (Li, Na, K, Mg, Ca, Zn, and Al are allowed as cations). More than six halogen atoms or multivalent halogens (except in counterions). Hydrocarbons. Reactive acid derivatives: halogenides, anhydrides, cyanides. Peroxides, isocyanates, azides, diazonium compounds, isonitriles. Phosphanes. Silicates.
  • 7
    • 0024716284 scopus 로고
    • Atomic Physicochemical Parameters for Three-Dimensional Structure-Directed Quantitative Structure-Activity Relationships. 4. Additional Parameters for Hydrophobic and Dispersive Interactions and Their Application for an Automated Superposition of Certain Naturally Occurring Nucleoside Antibiotics
    • Viswanadhan, V. N.; Ghose, A. K.; Revankar, G. R.; Robins, R. K. Atomic Physicochemical Parameters for Three-Dimensional Structure-Directed Quantitative Structure-Activity Relationships. 4. Additional Parameters for Hydrophobic and Dispersive Interactions and Their Application for an Automated Superposition of Certain Naturally Occurring Nucleoside Antibiotics. J. Chem. Inf. Comput. Sci. 1989, 29, 163-172.
    • (1989) J. Chem. Inf. Comput. Sci. , vol.29 , pp. 163-172
    • Viswanadhan, V.N.1    Ghose, A.K.2    Revankar, G.R.3    Robins, R.K.4
  • 9
    • 15444349963 scopus 로고
    • July 7
    • SCRIP No. 2040, July 7, 1995; p 23.
    • (1995) SCRIP No. 2040 , pp. 23
  • 10
    • 15444354504 scopus 로고    scopus 로고
    • Ajay, Vertex Pharmaceuticals, personal communication
    • Ajay, Vertex Pharmaceuticals, personal communication.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.