A structure-based library approach to kinase inhibitors

Journal of the American Chemical Society

Volumn 118, Issue 31, 1996, Pages 7430-7431

  Norman, Thea C ^a   Gray, Nathanael S ^a   Koh, John T ^a   Schultz, Peter G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; PHOSPHOTRANSFERASE;

ARTICLE; DRUG DESIGN; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 0029740469     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9614934     Document Type: Article

References (24)

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24. Crude lysates containing activated CDK2/cyclin A (Δ171, modified with His-6) were obtained from Professor David O. Morgan and purified to homogeneity.