Regulation of hepatic drug metabolism: Role of the nuclear receptors PXR and CAR

Seminars in Liver Disease

Volumn 22, Issue 2, 2002, Pages 115-122

  Liddle, Christopher ^a   Goodwin, Bryan ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Bile acids; Constitutive androstane receptor; Cytochrome P450; Drug disposition; Drug metabolism; Nuclear receptor; Pregnane X receptor

Indexed keywords

BILE ACID; CARRIER PROTEIN; CHOLESTEROL DERIVATIVE; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 2B; CYTOCHROME P450 2B6; CYTOCHROME P450 2C9; CYTOCHROME P450 3A; CYTOCHROME P450 3A23; CYTOCHROME P450 3A4; CYTOCHROME P450 3A6; CYTOCHROME P450 3A7; ENZYME; FATTY ACID DERIVATIVE; GLUCURONOSYLTRANSFERASE; GLYCERYL TRINITRATE; HORMONE RECEPTOR; HYODEOXYCHOLIC ACID; LEUKOTRIENE DERIVATIVE; LIDOCAINE; LITHOCHOLIC ACID; MORPHINE; PREGNANE X RECEPTOR; PROPRANOLOL; STEROID HORMONE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VITAMIN; XENOBIOTIC AGENT;

BILE ACID METABOLISM; CHOLESTEROL METABOLISM; DRUG DISPOSITION; DRUG METABOLISM; HUMAN; LIVER METABOLISM; METABOLIC REGULATION; NONHUMAN; PRIORITY JOURNAL; REVIEW; XENOBIOTIC METABOLISM;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BILE ACIDS AND SALTS; CHOLESTEROL; HOMEOSTASIS; HUMANS; LIVER; PHARMACEUTICAL PREPARATIONS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; TRANSCRIPTION FACTORS; XENOBIOTICS;

EID: 0036251522     PISSN: 02728087     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2002-30098     Document Type: Review

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