TEL-JAK2 Mediates Constitutive Activation of the Phosphatidylinositol 3′-Kinase/Protein Kinase B Signaling Pathway

Journal of Biological Chemistry

Volumn 276, Issue 35, 2001, Pages 32704-32713

  Nguyen, Melody H H ^a,b   Ho, Jenny M Y ^a,b   Beattie, Bryan K ^a   Barber, Dwayne L ^a,b,c  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b TORONTO GENERAL HOSPITAL   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHEMICAL ACTIVATION; ENZYMES; IMMUNOLOGY;

PHOSPHORYLATION; SIGNALING PATHWAY;

BIOCHEMISTRY;

2 MORPHOLINO 8 PHENYLCHROMONE; ADAPTOR PROTEIN; JANUS KINASE 2; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN GAB2; PROTEIN KINASE B; PROTEIN P85; PROTEIN TYROSINE KINASE; STAT1 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETV6; UNCLASSIFIED DRUG; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; CHROMONE DERIVATIVE; DNA BINDING PROTEIN; ENZYME INHIBITOR; GAB2 PROTEIN, MOUSE; HYBRID PROTEIN; INTERLEUKIN 3; JAK2 PROTEIN, MOUSE; MORPHOLINE DERIVATIVE; NUCLEAR PROTEIN; ONCOPROTEIN; PHOSPHOPROTEIN; PROTEIN SERINE THREONINE KINASE; RECOMBINANT PROTEIN; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR ETS;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SUBSTRATE; ENZYME SUBUNIT; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; AMINO ACID SUBSTITUTION; ANIMAL; CELL DIVISION; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; GENE TRANSLOCATION; GENETIC TRANSFECTION; GENETICS; KINETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SITE DIRECTED MUTAGENESIS;

ANIMALIA; JANUS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID SUBSTITUTION; ANIMALS; CELL DIVISION; CELL LINE; CELL SURVIVAL; CHROMONES; DNA-BINDING PROTEINS; ENZYME INHIBITORS; INTERLEUKIN-3; JANUS KINASE 2; KINETICS; MICE; MORPHOLINES; MUTAGENESIS, SITE-DIRECTED; NUCLEAR PROTEINS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-ETS; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION; TRANSLOCATION, GENETIC;

EID: 0035980056     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M103100200     Document Type: Article

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