Nucleophosmin-anaplastic lymphoma kinase associated with anaplastic large-cell lymphoma activates the phosphatidylinositol 3-kinase/Akt antiapoptotic signaling pathway

Blood

Volumn 96, Issue 13, 2000, Pages 4319-4327

  Bai, Ren Yuan ^b   Ouyang, Tao ^b   Miething, Cornelius ^b   Morris, Stephan W ^b   Peschel, Christian ^b   Duyster, Justus ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; AKT1 PROTEIN, HUMAN; AKT1 PROTEIN, RAT; ANDROSTANE DERIVATIVE; BAD PROTEIN, HUMAN; BAD PROTEIN, MOUSE; BAD PROTEIN, RAT; CARRIER PROTEIN; CHROMONE DERIVATIVE; ENZYME INHIBITOR; HYBRID PROTEIN; INTERLEUKIN 3; MORPHOLINE DERIVATIVE; ONCOPROTEIN; P80(NPM ALK) PROTEIN; P80(NPM-ALK) PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAD; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; PROTEIN SUBUNIT; PROTEIN TYROSINE KINASE; TUMOR PROTEIN; WORTMANNIN;

AMINO ACID SUBSTITUTION; ANIMAL; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; BINDING COMPETITION; BINDING SITE; CELL LINE; CELL SURVIVAL; CELL TRANSFORMATION; COCULTURE; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; FIBROBLAST; GENETIC TRANSFECTION; GENETICS; HEMATOPOIETIC STEM CELL; HISTIOCYTIC LYMPHOMA; HUMAN; METABOLISM; MOUSE; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; POINT MUTATION; PROTEIN PROCESSING; RAT; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; SRC HOMOLOGY DOMAIN; STROMA CELL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID SUBSTITUTION; ANDROSTADIENES; ANIMALS; APOPTOSIS; BCL-ASSOCIATED DEATH PROTEIN; BINDING SITES; BINDING, COMPETITIVE; CARRIER PROTEINS; CELL LINE, TRANSFORMED; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; CHROMONES; COCULTURE TECHNIQUES; ENZYME ACTIVATION; ENZYME INHIBITORS; FIBROBLASTS; HEMATOPOIETIC STEM CELLS; HUMANS; INTERLEUKIN-3; LYMPHOMA, LARGE-CELL; MICE; MICE, INBRED BALB C; MORPHOLINES; MUTAGENESIS, SITE-DIRECTED; NEOPLASM PROTEINS; PHOSPHORYLATION; POINT MUTATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN SUBUNITS; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; STROMAL CELLS; TRANSFECTION;

EID: 0034672140     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v96.13.4319     Document Type: Article

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