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Volumn 20, Issue 42, 2001, Pages 6073-6083

Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer

(10) Chen, Xufeng a Thakkar, Hitesh a Tyan, Frazier a Gim, Suzanna a Robinson, Heather a Lee, Calvin a Pandey, Sanjay K b Nwokorie, Chichi a Onwudiwe, Nneka a Srivastava, Rakesh K a

a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY (United States)

b NATIONAL INSTITUTE ON AGING (United States)

Author keywords

Akt; Apoptosis; Mitochondria; Prostate cancer; PTEN; TRAIL

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE 8; CYCLOHEXIMIDE; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN BCL 2; PROTEIN BCL X; PROTEIN KINASE B; REGULATOR PROTEIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; WORTMANNIN;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DEGRADATION; PROTEIN SYNTHESIS INHIBITION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CARRIER PROTEINS; CASPASE 8; CASPASE 9; CASPASES; CELL SURVIVAL; CHROMONES; DRUG RESISTANCE, NEOPLASM; ENZYME INHIBITORS; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MITOCHONDRIA; MORPHOLINES; MUTATION; PROSTATIC NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

MUS MUSCULUS;

EID: 0035921762 PISSN: 09509232 EISSN: None Source Type: Journal
DOI: 10.1038/sj.onc.1204736 Document Type: Article

Times cited : (267)

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