Analysis of PTEN/MMAC1 alterations in aerodigestive tract tumors

Cancer Research

Volumn 58, Issue 3, 1998, Pages 509-511

  Okami, Kenji ^a,b   Wu, Li ^a   Riggins, Greg ^a   Cairns, Paul ^a   Goggins, Michael ^a   Evron, Ella ^a   Halachmi, Naomi ^a   Ahrendt, Steven A ^a   Reed, Andre L ^a   Hilgers, Werner ^a   Kern, Scott E ^a   Koch, Wayne M ^a   Sidransky, David ^a   Jen, Jin ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YAMAGUCHI UNIVERSITY   (Japan)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ARTICLE; CANCER CELL CULTURE; CHROMOSOME 10Q; COLON CANCER; CONTROLLED STUDY; DIGESTIVE SYSTEM CANCER; DNA SEQUENCE; GENE DELETION; GENE MUTATION; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG CANCER; LUNG NON SMALL CELL CANCER; PANCREAS CANCER; PRIORITY JOURNAL; RESPIRATORY TRACT CANCER; STOMACH CANCER; TUMOR SUPPRESSOR GENE; TUMOR XENOGRAFT;

EID: 0032006029     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Li, J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S. I., Puc, J., Miliaresis, C., Rodgers, L., McCombie, R., Bigner, S. H., Giovanella, B. C., Ittman, M., Tycko, B., Hibshoosh, H., Wigler, M. H., and Parsons, R. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science (Washington DC), 275: 1943-1947, 1997.
2. Nawroz, H., van der Riet, P., Hruban, R. H., Koch, W., Ruppert, J. M., and Sidransky. D. Allelotype of head and neck squamous cell carcinoma. Cancer Res., 54: 1152-1155, 1994.
3. Tsuchiya, E., Nakamura, Y., Weng, S-Y., Nakagawa, K., Tsuchiya, S., Sugano, H., and Kitagawa, T. Allelotype of non-small cell lung carcinoma: comparison between loss of heterozygosity in squamous cell carcinoma and adenocarcinoma. Cancer Res., 52.: 2478-2481, 1992.
4. Sato S., Nakamura, Y., and Tsuchiya, E. Difference of allelotype between squamous cell carcinoma and adenocarcinoma of the lung. Cancer Res., 54: 5652-5655, 1994.
5. Hahn, S. A., Seymour, A. B., Howue, A. T. M., Schutte, M., da Costa, L. T., Redston, M. S., Caldas, C., Weinstein, C. L., Fischer, A., Yeo, C. J., Hruban, R. H., and Kern, A. E. Allelotype of pancreatic adenocarcinoma using xenograft enrichment. Cancer Res., 55: 4670-4675, 1995.
6. Steck, P. A., Pershouse, M. A., Jasser, S. A., Yung, W. K. A., Lin, H., Ligon, A. H., Langford, L. A., Baumgard, M. L., Hattier, T., Davis, T., Frye, C., Hu, R., Swedlund, B., Teng, D. H. F., and Tavtigian, S. V. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat. Genet., 15: 356-362, 1997.
7. Liaw, D., Marsh, D. J., Li, J., Dahia, P. L. M., Wang, S. L. Zheng, Z., Bose, S., Call, K. M., Tsou, H. C., Peacocke, M., Eng, C., and Parsons, R. Germline mutations of the PTEN gene in Cowden's disease, an inherited breast and thyroid cancer syndrome. Nat. Genet., 16: 64-67, 1997.
8. van der Riet, P., Nawroz, H., Hruban, R. H., Corio, R., Tokino, K., Koch, W., and Sidransky, D., Frequent loss of chromosome 9p21-22 early in head and neck cancer progression. Cancer Res., 54: 1156-1158, 1994.
9. Califano, J., van der Riet, P., Westra, W., Nawroz, H., Clayman, G., Piantadosi, S., Corio, R., Lee, D., Greenberg, B., Koch, W., and Sidransky, D., Genetic progression model for head and neck cancer: implication for field cancerization. Cancer Res., 56: 2488-2492, 1996.
10. Caldas, C., Hahn, S. A., da Costa, L. T., Redston, M. S., Schutte, M., Seymour, A. B., Weinstein, C. L., Hruban, R. H., Yeo, C. J., and Kern, S. E. Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma. Nat. Genet., 8: 27-32, 1994.
11. Cairns, P., Okami, K., Halachmi, S., Halachmi, N., Esteller, M., Herman, J. G., Jen, J., and Sidransky, D. Frequent inactivation of PTEN/MMAC1 in primary prostate cancer. Cancer Res., 57: 5356-5359, 1997.
12. Cairns, P., Polaiscik, T. J., Eby, Y., Tokino, K., Califano, J., Merlo, A., Mao, L., Herath, J., Jenkins, R., Westra, W., Rutter, J. L., Buckler, A., Gabrielson, E., Tockman, M., Cho, K. R., Hedrick, L., Bova, G. S., Isaacs, W., Koch, W., Schwab, D., and Sidransky, D. Frequency of homozygous deletion at p16/CDKN2 in primary human tumours. Nat. Genet., 11: 210-212, 1995.
13. Evron, E., Cairns, P., Halachmi, N., Ahrendt, S. A., Reed, A. L., and Sidransky, D. Normal polymorphism in the incomplete trinucleotide repeat of the arginine rich protein gene. Cancer Res., 57: 2888-2889, 1997.
14. Powell, S. M., Peterson, G. M., Krush, A. J., Booker, S., Jen, J., Giardiello, F. M., Hamilton, S. R., Vogelstein, B., and Kinder, K. W. Molecular diagnosis of familial adenomous polyposis. N. Engl. J. Med., 329: 1982-1987, 1993.
15. Herman, J. G., Latif, F., Weng, Y., Lerman, M. I., Zbar, B., Liu, S., Samid, D., Duan, D. R., Gnarra, J. R., Linehan, W. M., and Baylin, S. B. Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma. Proc. Natl. Acad. Sci. USA, 91: 9700-9704, 1994.
16. Merlo, A., Herman, J. G., Mao, L., Lee, D. J., Gabrielson, H., Burger, P. C., Baylin, S. B., and Sidransky, D. 5′ CpG island methylation is associated with transcriptional silencing of the tumor suppressor p16/CDKN2/MTS1 in human cancers. Nat. Med., 1: 686-692, 1995.