Gamma-delta T cells: Immunoregulatory functions and immunoprotection

Chemical Immunology

Volumn 79, Issue , 2001, Pages 99-138

  Cai, Ji Lian ^a   Tucker, Philip W ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; AMINO ACID; ANTIGEN; CD2 ANTIGEN; CD28 ANTIGEN; CD4 ANTIGEN; CD40 ANTIGEN; CD8 ANTIGEN; CD94 ANTIGEN; CYTOKINE; DNA; GAMMA INTERFERON; GENE PRODUCT; HEAT SHOCK PROTEIN; HLA B ANTIGEN; IMMUNOGLOBULIN HEAVY CHAIN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12 RECEPTOR; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 7; MAJOR HISTOCOMPATIBILITY ANTIGEN; PERFORIN; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG; VIRUS GLYCOPROTEIN;

ALLERGIC ENCEPHALOMYELITIS; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; AUTOIMMUNITY; BLOOD; CELL INTERACTION; CYTOKINE PRODUCTION; EPITHELIUM; GENE; GENE EXPRESSION; GENE REARRANGEMENT; GENETIC POLYMORPHISM; HUMAN; IMMUNITY; IMMUNOREGULATION; INFECTION; INFLAMMATION; KERATINOCYTE; MULTIPLE SCLEROSIS; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW; SPLEEN; T LYMPHOCYTE; THYMUS; TUMOR IMMUNITY;

EID: 0035744641     PISSN: 10150145     EISSN: None     Source Type: Journal    
DOI: 10.1159/000058827     Document Type: Review

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183. V delta 1 T cells expanded in the blood throughout HIV infection display a cytotoxic activity and are primed for TNF-alpha and IFN-gamma production but are not selected in lymph nodes
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185. The role of the thymus in modulating γδ cell suppressor activity during experimental Trypanosoma cruzi infection
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188. Expansion of mycobacterium-reactive γδ cells by a subset of memory helper T cells
189. Cross-talk between Vβ8+ and γδ lymphocytes in contact sensitivity
190. Pathogenic anti-DNA autoantibody-inducing T helper cell lines from patients with active lupus nephritis: Isolation of CD4-CD8- T helper lines that express the γδ T cell antigen receptor
191. Activation of γδ T cells for IFN-γ production is mediated by bacteria via macrophage-derived cytokines IL-1 and IL-2
192. Alveolar macrophages as accessory cells for human γδ T cells activated by Mycobacterium tuberculosis
193. Recognition of self antigens by skin derived T cells with invariant γδ antigen receptors
194. Mucosal T lymphocyte numbers are selectively reduced in integrin alpha E (CD 103) deficient mice
195. A tumor-suppressor function for Fas (CD95) revealed in T cell deficient mice
196. Human gamma delta T cells recognize heat shock protein-60 on oral tumor cells
197. Enhancing effect of tumor necrosis factor (TNF)-alpha, but not IFN-gamma, on the tumor-specific cytotoxicity of gammadelta T cells from glioblastoma patients
198. + and CD4-T cell receptor - γδ clones from peripheral blood
199. + T cells provide B-cell help
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201. Regulation of IgE responses to inhaled antigen in mice by antigen-specific γδ T cells
202. Aerosol-induced immunoglobulin (Ig)-E unresponsiveness to ovalbumin does not require CD8+ or T cell receptor (TCR)-γ/δ+ T cells or interferon (IFN)-γ in a murine model of allergen sensitization
203. Experimental models of inflammatory bowel disease
204. Increase of circulating γ/δ T lymphocytes in the peripheral blood of patients affected by active inflammatory bowel disease
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206. Different roles of αβ and γδ T cells in immunity against an intracellular pathogen
207. Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice
208. Gamma delta intraepithelial lymphocytes drive tumor necrosis factor-alpha responsiveness to intestinal iron challenge: Relevance to hemochromatosis
209. CD8+CD103+ T cells analogous to intestinal intraepithelial lymphocytes infiltrate the pancreas in chronic pancreatitis
210. Function of intestinal gammadelta T cells
211. Homeostatic regulation of intestinal epithelia by intraepithelial γ-δ T cells
212. Modulation of epithelial cell growth by intraepithelial γ-δ cells
213. Role of γδ T cells in a murine colitis model
214. Molecular and cellular biology of dendritic epidermal T cells
215. Activation and control of self-reactive γδ T cells
216. Transgenic mice as an in vivo model for self-reactivity
217. T cell function, expression are dramatically altered in T cell receptor Vgamma 1.1 Jgamma4 Cgamma4 transgenic mice
218. The vitronectin receptor serves as an accessory molecule for the activation of a subset of gamma/delta T cells
219. T cell target 1 (TCT.1): A novel target molecule for human non-major histocompatibility complex-restricted T lymphocytes
220. Activation, activation-driven death of human gamma/delta T cells
221. Activation of γδ T cells by mycobacterial antigens in rheumatoid arthritis
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223. T γδ cells in juvenile rheumatoid arthritis and rheumatoid arthritis
224. Immunohistologic study of T-cell receptor γ-chain expression in rheumatoid synovial membrane
225. Evidence for oligoclonality of T cell receptor 8 chain transcripts expressed in rheumatoid arthritis patients
226. Molecular characterization of the Vγ9 T cell receptor repertoire expressed in patients with rheumatoid arthritis
227. Persistence of γδ T cell oligoclonality in the peripheral blood of rheumatoid arthritis patients
228. Density of gamma/delta+ T cells in the jejunal epithelium of patients with coeliac disease and dermatitis herpetiformis is increased with age
229. Studies in vivo of omegagliadins in gluten sensitivity (coeliac sprue disease)
230. Changing jejunal gamma delta T cell receptor (TCR)-bearing intraepithelial lymphocyte density in coeliac disease
231. Propagation and regulation of systemic autoimmunity by γδ T cells
232. Extrathymic derivation of gut lymphocytes in parabiotic mice
233. Adoptively transferred EAE in gamma delta T cell-knockout mice
234. Role of natural killer cells and TCR gamma delta T cells in acute autoimmune encephalomyelitis
235. Oligoclonal expansion of V delta 1+ gamma/delta T cells in systemic, sclcrosis patients
236. Circulating Vdeltal+ T cells are activated and accumulate in the skin of systemic sclerosis patients
237. The role of gamma/delta T cell receptor positive cells in pregnancy
238. A subset of γδ T-cell receptor cells produce T-helper type-2 cytokines and regulate mouse skin graft rejection following portal venous pretransplant preimmunization
239. Graft-facilitating doses of ex vivo activated gammadelta T cells do not cause lethal murine graft-vs.-host disease
240. Activation of gamma delta T cells in the primary immune response to Mycobacterium tuberculosis
241. Kinetics of accumulation of gamma delta receptor bearing T lymphocytes in mice infected with live mycobactcria
242. Early appearing gamma/delta-bearing T cells during infection with Calmette-Guérin bacillus
243. An increase in number of gamma-delta bearing T cells in athymic nude mice treated with complete Freund's adjuvants
244. A murine CD4-CD8- T cell receptor-γδ T lymphocyte clone specific for herpes simplcx virus glycoprotein I
245. Heat shock protein Hsp60-reactive gamma delta cells: A large diversified T-lymphocyte subset with highly focused specificity
246. Contribution of alpha/beta and gamma/delta T lymphocytes to immunity against Mycobacterium bovis bacillus Calmette-Gu6rin studies with T cell receptor-deficient mutant mice
247. Increased gamma-delta T-lymphocyte response to Mycobacterium bovis BCG in major histocompatibility complex class I-deficient mice
248. An anti-inflammatory role for γδ T cells in acquired immunity to Mycobacterium tuberculosis
249. The T cell receptors of human gamma delta T cells reactive to Mycobacterium tuberculosis are encoded by specific V genes but diverse V-J junctions
250. A predominance of the T cell receptor V gamma2/V delta 2 subset in human mycobacteria-responsive T cells suggests gcrmline gene encoded recognition
251. Patterns of phosphoantigen stimulation of human V gamma9/V delta2 T cell clones including Th0 cytokines
252. CD4+ alpha beta T cell and gamma delta T cell responses to Mycobacterium tuberculosis, similarities and differences in Ag recognition cytotoxic effector function and cytokine production
253. ATP-induced killing of mycobacteria by human macrophages is mediated by purinergic P2Z (P2X7) receptors
254. Gamma/delta T lymphocytes express CD40 ligand and induce isotype switching in B lymphocytes
255. Involvement of Fas/Fas-ligand pathway in activation-induced cell death of mycobacteria-reactive human gamma delta T cells: A mechanism for the loss of gamma delta T cells in patients with pulmonary tuberculosis
256. Mycobacterium tuberculosis exploits the CD95/CD95 ligand system of gammadelta T cells to cause apoptosis
257. Generation of nitric oxide by the inducible nitric oxide synthase protects gamma delta T cells from Mycobacterium tuberculosis-induced apoptosis
258. T cell receptor gamma/delta+ lymphocyte subsets during HIV infection
259. Selective increase of a subset of T cell receptor gamma delta T lymphocytes in the peripheral blood of patients with human immunodeficiency virus type 1 infection
260. Gamma delta T cell receptor-bearing lymphocytes during Epstein-Barr virus infection
261. Recognition and destruction of virus-infected cells by human gamma delta CTL
262. Inflammatory infiltration of the trigeminal ganglion after herpes simplex virus type 1 corneal infection
263. Interferon gamma-producing gammadelta T cell-dependent antibody isotypc switching in the absence of germinal center formation during virus infection
264. Alpha beta and gamma delta T-cell networks and their roles in natural resistance to viral infection
265. T cells expressing the gamma delta T-ccll receptor potentiate coxsackievirus B3-induced myocarditis
266. Gamma delta+ T cells regulate major histocompatibility complex class II(IA and IE)-dependent susceptibility to coxsackievirus B3-induced autoimmune myocarditis
267. Modulation of cytokine expression by CD4+ T cells during coxsackievirus B3 infections of BALB/c mice initiated by cells expressing the gamma delta+ T-cell receptor
268. HLA-unrestricted killing of HSV-1-infectcd mononuclear cells. Involvement of either gamma/delta+ or alpha/beta+ human cytotoxic T lymphocytes
269. CDR3-independent gamma delta V delta1+ T cell expansion in the peripheral blood of HIV-infected persons
270. T cell receptor gamma delta repertoire in HIV-1-infected individuals
271. Herpes simplex virus-specific human cytotoxic T-cell colonies expressing either γδ or αβ T-cell receptor role of accessory molecules on HLA-unrestricted killing of virus-infected targets
272. Gamma delta+ T cells preferentially respond to live rather than killed malaria parasites
273. Murine gamma delta T lymphocytes elicited during Plasmodium yoelii infection respond to Plasmodium heat shock proteins
274. Gamma delta T cells contribute to control of chronic parasitemia in Plasmodium chabaudi infections in mice
275. Small cytoplasmic antigens from Pseudomonas aeruginosa stimulate gamma delta T lymphocytes
276. Protective roles of gamma delta T cells and interleukin-I 5 in Escherichia coli infection in mice
277. Normal macrophage functions, but impaired induction of gamma delta T cells, at the site of bacterial infection in CD45 exon 6-deficient mice
278. Disruption of cellular inflammatory response to Listeria monocytogenes infection in mice with disruptions in targeted genes
279. Control of natural killer cell-mediated innatc resistance against the intracellular pathogen Listeria monocytogenes by γ/δ T lymphocytes
280. In vivo and in vitro activation and expansion of gamma delta T cells during Listeria monocytogenes infection in humans