Killing of laminin receptor-positive human lung cancers by tumor-infiltrating lymphocytes bearing γδ+ T-cell receptors

Journal of the National Cancer Institute

Volumn 88, Issue 7, 1996, Pages 436-441

  Ferrarini, Marina ^a   Heltai, Silvia ^a   Pupa, Serenella M ^b   Menard, Sylvie ^b   Zocchi, M Raffaella ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

LAMININ RECEPTOR; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY MLUC5; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER IMMUNOTHERAPY; CYTOTOXICITY; DRUG ACTIVITY; DRUG SCREENING; HUMAN; HUMAN CELL; LUNG CANCER; LYMPHOKINE ACTIVATED KILLER CELL; NATURAL KILLER CELL; T LYMPHOCYTE; TUMOR ASSOCIATED LEUKOCYTE;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; BURKITT LYMPHOMA; CARCINOMA, SMALL CELL; CELL LINE; CYTOTOXICITY, IMMUNOLOGIC; HUMANS; KILLER CELLS, LYMPHOKINE-ACTIVATED; KILLER CELLS, NATURAL; LUNG NEOPLASMS; LYMPHOCYTES, TUMOR-INFILTRATING; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; RECEPTORS, LAMININ; T-LYMPHOCYTE SUBSETS; TUMOR CELLS, CULTURED;

EID: 0030005677     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/88.7.436     Document Type: Article

References (27)

1. Haas W, Pereira P, Tonegawa S. Gamma/delta cells. Annu Rev Immunol 1993;11:637-85.
2. Modlin RL, Pirmez C, Hofman FM, Torigian V, Uyemura K, Rea TH, et al. Lymphocytes bearing antigen-specific gamma delta T-cell receptors accumulate in human infectious disease lesions. Nature 1989;339:544-8.
3. Spencer J, Isaacson PG, Diss TC, MacDonald TT. Expression of disulfide-linked and non-disulfide-linked forms of the T cell receptor gamma delta heterodimer in human intestinal intraepithelial lymphocytes. Eur J Immunol 1989;19:1335-8.
4. Kaufmann SH, Kabelitz D. Gamma/delta T lymphocytes and heat shock proteins. Curr Top Microbiol Immunol 1991;167:191-207.
5. Zocchi MR, Ferrarini M, Rugarli C. Selective lysis of the autologous tumor by delta TCS1+ gamma/delta tumor-infiltrating lymphocytes from human lung carcinomas. Eur J Immunol 1990;20:2685-9.
6. Ferrarini M, Pupa SM, Zocchi MR, Rugarli C, Menard S. Distinct pattern of HSP72 and monomeric laminin receptor expression in human lung cancers infiltrated by gamma/ delta T lymphocytes. Int J Cancer 1994;57: 486-90.
7. Zocchi MR, Ferrarini M, Migone N, Casorati G. T-cell receptor V delta gene usage by tumour reactive gamma delta T lymphocytes infiltrating human lung cancer. Immunology 1994;81:234-9.
8. Ferrarini M, Heltai S, Chiesa G, Sabbadini MG. V delta 1+ gamma/delta T lymphocytes infiltrating human lung cancer express the CD8 alpha/alpha homodimer. Scand J Immunol 1994;40:363-7.
9. Mecham RP. Laminin receptors. Annu Rev Cell Biol 1991;7:71-91.
10. Hand PH, Thor A, Schlom J, Rao CN, Liotta L. Expression of laminin receptor in normal and carcinomatous human tissues as defined by a monoclonal antibody. Cancer Res 1985;45:2713-9.
11. Wewer UM, Taraboletti G, Sobel ME, Albrechtsen R, Liotta LA. Role of laminin receptor in tumor cell migration. Cancer Res 1987;47:5691-8.
12. Cioce V, Castronovo V, Shmookler MB, Garbisa S, Grigioni WF, Liotta LA, et al. Increased expression of the laminin receptor in human colon cancer. J Natl Cancer Inst 1991;83:29-36.
13. Martignone S, Menard S, Bufalino R, Cascinelli N, Pellegrini R, Tagliabue E, et al. Prognostic significance of the 67-kilodalton laminin receptor expression in human breast carcinomas. J Natl Cancer Inst 1993;85:398-402.
14. Boyum A. Isolation of mononuclear cells and granulocytes from human blood. Isolation of mononuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at Ig. Scand J Clin Lab Invest Suppl 1968;97:77-89.
15. Julius MH, Simpson E, Herzenberg LA. A rapid method for the isolation of functional thymus-derived murine lymphocytes. Eur J Immunol 1973;3:645-9.
16. Martignone S, Pellegrini R, Villa E, Tandon NN, Mastroianni A, Tagliabue E, et al. Characterization of two monoclonal antibodies directed against the 67 kDa high affinity laminin receptor and application for the study of breast carcinoma progression. Clin Exp Metastasis 1992;10:379-86.
17. Lanier LL, Le AM, Phillips JH, Warner NL, Babcock GF. Subpopulations of natural killer cells defined by expression of the Leu-7 (HNK-1) and Leu-11 (NKP-15) antigens. J Immunol 1983;13:1789-96.
18. Fisch P, Malkovsky M, Kovats S, Sturm E, Braakman E, Klein BS, et al. Recognition by human V gamma 9/V delta 2 T cells of a GroEL homolog on Daudi Burkitt's lymphoma cells. Science 1990;250:1269-73.
19. Fisch P, Malkovsky M, Braakman E, Sturm E, Bolhuis RL, Prieve A, et al. Gamma/delta T cell clones and natural killer cell clones mediate distinct patterns of non-major histocompatibility complex-restricted cytolysis. J Exp Med 1990;171:1567-79.
20. Ferrarini M, Heltai S, Toninelli E, Sabbadini MG, Pellicciari C, Manfredi AA. Daudi lymphoma killing triggers the programmed death of cytotoxic V gamma 9/V delta 2 T lymphocytes. J Immunol 1995;154:3704-12.
21. Graf J, Iwamoto Y, Sasaki M, Martin GR, Kleinman HK, Robey FA, et al. Identification of an amino acid sequence in laminin mediating cell attachment, chemotaxis, and receptor binding. Cell 1987;48:989-96.
22. Kanemoto T, Reich R, Royce L, Greatorex D, Adler SH, Shiraishi N, et al. Identification of an amino acid sequence from the laminin A chain that stimulates metastasis and collagenase IV production. Proc Natl Acad Sci U S A 1990;87:2279-83.
23. + subset of human gamma delta T cells responds to ligands expressed by EBV-infected Burkitt lymphoma cells and transformed B lymphoctyes. J Immunol 1992;149:3984-9.
24. Hemler ME. VLA proteins in the integrin family: structures, functions, and their role on leukocytes. Annu Rev Immunol 1990;8:365-400.
25. Mastroianni A, Invemizzi L, Tagliabue E, Fassina G, Albini A, Menard S, et al. Alteration of laminin production in small-cell lung carcinoma: possible correlation with the absence of the basement membrane. Tumour Biol 1993;14:279-87.
26. Nakano T, Iwahashi N, Maeda J, Hada T, Higashino K. Serum laminin P1 in small cell lung cancer: a valuable indicator of distant metastasis? Br J Cancer 1992;65:608-12.
27. Testi R, D'Ambrosio D, De Maria R, Santoni A. The CD69 receptor: a multipurpose cell-surface trigger for hematopoietic cells. Immunol Today 1994;15:479-83.