An Anti-Inflammatory Role for γδ T Lymphocytes in Acquired Immunity to Mycobacterium tuberculosis

Journal of Immunology

Volumn 158, Issue 3, 1997, Pages 1217-1221

  D'Souza, Celine D ^a   Cooper, Andrea M ^a   Frank, Anthony A ^a   Mazzaccaro, Richard J ^b   Bloom, Barry R ^b   Orme, Ian M ^a  

^a Veterinary Dentistry and Oral Surgery   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; LYMPHOCYTE ANTIGEN RECEPTOR; MESSENGER RNA;

ANIMAL; ARTICLE; C57BL MOUSE; CELLULAR IMMUNITY; GENE EXPRESSION; GENETICS; IMMUNOLOGY; LUNG; MICROBIOLOGY; MOUSE; MOUSE MUTANT; MYCOBACTERIUM TUBERCULOSIS; PATHOLOGY; T LYMPHOCYTE SUBPOPULATION; TIME; TUBERCULOSIS;

ANIMALS; CYTOKINES; GENE EXPRESSION; IMMUNITY, CELLULAR; LUNG; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYCOBACTERIUM TUBERCULOSIS; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; RNA, MESSENGER; T-LYMPHOCYTE SUBSETS; TIME FACTORS; TUBERCULOSIS;

EID: 0031067995     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Orme, I. M., P. Andersen, and W. H. Boom. 1993. T cell responses to Mycobacterium tuberculosis. J. Infect. Dis. 167:1481.
2. Kronenberg, M. 1994. Antigens recognized by γδ T cells. Curr. Opin. Immunol. 6:64.
3. Dannenberg, A. M. 1991. Delayed-type hypersensitivity and cell-mediated immunity in the pathogenesis of tuberculosis. Immunol. Today 12:228.
4. Orme. I. M., A. D. Roberts, J. P. Griffin and J. S. Abrams. 1993. Cytokine secretion by CD4 T lymphocytes acquired in response to Mycobacterium tuberculosis infection. J. Immunol. 151:518.
5. Cooper, A. M., D. K. Dalton, T. A. Stewart, J. P. Griffin, D. G. Russell and I. M. Orme. 1993. Disseminated tuberculosis in interferon γ gene-disrupted mice. J. Exp. Med. 178:2243.
6. Orme, I. M., and F. M. Collins. 1994. Mouse model of tuberculosis. In Tuberculosis: Pathogenesis, Protection, and Control. B. R. Bloom, ed. ASM Press, Washington, DC, pp. 113-134.
7. Flynn, J. L., M. M. Goldstein, K. J. Triebold, B. Koller, and B. R. Bloom. 1992. Major histocompatability complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection. Proc. Natl. Acad. Sci. USA 89:12011.
8. + T cells in immunity to tuberculosis infections. Trends Microbiol. 1:77.
9. Modlin, R. L., C. Pirmetz, F. M. Hofman, V. Torigian, K. Uyemura, T. H. Rea, B. R. Bloom, and M. B. Brenner. 1989. Lymphocytes bearing antigen-specific γδ T cell receptors accumulate in human infectious disease lesions. Nature 339:544.
10. Griffin, J. P., K. V. Harshan, W. K. Born, and I. M. Orme. 1991. Kinetics of accumulation of γδ receptor-bearing T lymphocytes in mice infected with live mycobacteria. Infect. Immun. 59:4263.
11. + α/β T cell and γ/δ T cell responses to Mycobacterium tuberculosis: similarities and differences in antigen recognition, cytotoxic effector function, and cytokine production. J. Immunol. 154:1786.
12. Fu, Y. X., R. Cranfill, M. Vollmer, R. van Der Zee, R. L., O'Brien, and W. Born. 1993. In vivo response of murine gamma delta T cells to a heat shock protein derived peptide. Proc. Natl. Acad. Sci. USA 90:322.
13. Boom, W. H., K. N. Balaji, R. Nayak, K. Tsukaguchi, and K. A. Chervenak. 1994. Characterisation of a 10- to 14-kD protease sensitive Mycobacterium tuberculosis H37Ra antigen that stimulates human γδ T cells. Infect. Immun. 62: 5511.
14. Constant, P., F. Davodeau, M. Peyrat, Y. Poquet, G. Puzo, M. Bonneville, and J. J. Fournie. 1994. Stimulation of human γδ T cells by non-peptidic mycobacterial ligands. Science 264:267.
15. Tanaka, Y., C. T. Morita, Y. Tanaka, E. Nieves, M. B. Brenner, and B. R. Bloom. 1995. Natural and synthetic non-peptide antigens recognized by human gamma delta T cells. Nature 375:155.
16. Ladel, C. H., C. Blum, A. Dreher, K. Reifenberg, and S. H. E. Kaufman. 1995. Protective role of γ/δ T cells and α/β T cells in tuberculosis. Eur. J. Immunol. 25:2877.
17. Itohara, S., P. Mombaerts, J. Lafaille, J. Iacomini, A. Nelson, A. R. Clarke, M. L. Hooper, A. Farr, and S. Tonegawa. 1992. T cell receptor δ gene mutant mice: independent generation of αβ T cells and programmed rearrangements of γδ TCR genes. Cell 72:337.
18. Rhoades, E. R., A. M. Cooper, and I. M. Urme. 1995. Chemokine response in mice infected with Mycobacterium tuberculosis. Infect. Immun. 63:3871.
19. Haas, W., P. Pereira, and S. Tonegawa. 1993. Gamma/delta cells. Annu. Rev. Immunol. 11:637.
20. Janeway, C. R. 1988. Frontiers in the immune response. Nature 333:804.
21. Friedland, J. S. 1994. Chemotactic cytokines and tuberculosis. Biochem. Soc. Trans. 22:310.
22. Gong, J. H., and I. Clark-Lewis. 1995. Antagonists of monocyte chemoattractant protein 1 identified by modification of functionally critical NH2-terminal residues. J. Exp. Med. 181:631.
23. Fu, Y. X., C. E. Roark, K. Kelly, D. Drevets, P. Campbell, R. O'Brien, and W. Born. 1994. Immune protection and control of inflammatory tissue necrosis by gamma delta T cells. J. Immunol. 153:3101.
24. Follows, G. A., M. E. Munk, A. J. Gatrill, P. Conradt, and S. H. E. Kaufmann. 1992. Gamma-interferon and interleukin-2, but not interleukin-4, are detectable in gamma-delta T-cell cultures after activation with bacteria. Infect. Immun. 60:1229.
25. Kaufmann, S. H. E. 1990. Heat shock proteins and the immune response. Immunol. Today 11:129.
26. Orme, I. M., E. S. Miller, A. D. Roberts, S. K. Furney, J. P. Griffin, K. M. Dobos, D. Chi, B. Rivoire, and P. J. Brennan. 1992. T lymphocytes mediating protection and cellular cytolysis during the course of Mycobacterium tuberculosis infection. J. Immunol. 148:189.