Conservation of T cell receptor conformation in epidermal γδ cells with disrupted primary V(γ) gene usage

Science

Volumn 279, Issue 5357, 1998, Pages 1729-1733

  Mallick Wood, Caroline A ^a   Lewis, Julia M ^a   Richie, Lauren I ^a   Owen, Michael J ^a   Tigelaar, Robert E ^a   Hayday, Adrian C ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CD3 ANTIGEN; EPITOPE; IMMUNOGLOBULIN; IMMUNOGLOBULIN IDIOTYPE; MONOCLONAL ANTIBODY; T LYMPHOCYTE RECEPTOR;

ARTICLE; AUTORADIOGRAPHY; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; DENDRITIC CELL; EPIDERMIS CELL; FLOW CYTOMETRY; GENE; GENE DISRUPTION; IMMUNE RESPONSE; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE;

ANIMALS; CELL LINE; DENDRITIC CELLS; EPIDERMIS; EPITOPES; FEMALE; GENE REARRANGEMENT; HYBRIDOMAS; MALE; MICE; MICE, INBRED C57BL; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PROTEIN CONFORMATION; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTE SUBSETS;

EID: 0032513352     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.279.5357.1729     Document Type: Article

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44. Supported by NIH grants GM37759 and AI27855 (A.C.H.) and AI27404 (R.E.T.). We thank our colleagues for discussion; L. McVay for isolation of genomic clones; T. Taylor for FACS analysis; I. Rosewell and S. Donaldson for mouse work; and M. Bonneville, W. Born, K. Bottomly, L. Lefrancois, P. Pereira, E. Shevach, A. Takashima, and S. Tonegawa for provision of reagents. All animal experiments were performed under accredited conditions after prior approval of protocols by the local Animal Care and Use Committee.