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Volumn 21, Issue 5, 2001, Pages 399-425

Macrophage arginine metabolism to ornithine/urea or nitric oxide/citrulline: A life or death issue

Author keywords

Arginase; Dendritic cells; Macrophages; Nitric oxide; Ornithine

Indexed keywords

ARGININE; CITRULLINE; COLLAGEN; NITRIC OXIDE; ORNITHINE; POLYAMINE; UREA;

EID: 0035727293     PISSN: 10408401     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (176)

References (231)
  • 15
    • 0032211131 scopus 로고    scopus 로고
    • Activation of the RON receptor tyrosine kinase inhibits inducible nitric oxide synthase (iNOS) expression by murine peritoneal exudate macrophages: Phosphatidylinositol-3 kinase is required for RON-mediated inhibition of iNOS expression
    • (1998) J. Immunol. , vol.161 , pp. 4950
    • Chen, Y.Q.1    Fisher, J.H.2    Wang, M.H.3
  • 16
    • 0034663958 scopus 로고    scopus 로고
    • The involvement of tyrosine kinases, cyclic AMP/protein kinase A, and p38 mitogen-activated protein kinase in IL-13-mediated arginase I induction in macrophages: Its implications in IL-13-inhibited nitric oxide production
    • (2000) J. Immunol. , vol.165 , pp. 2134
    • Chang, C.I.1    Zoghi, B.2    Liao, J.C.3    Kuo, L.4
  • 21
    • 0023940538 scopus 로고
    • Differentiation of murine macrophages to express nonspecific cytotoxicity for tumor cells results in L-arginine-dependent inhibition of mitochondrial iron-sulfur enzymes in the macrophage effector cells
    • (1988) J. Immunol. , vol.140 , pp. 2829
    • Drapier, J.C.1    Hibbs Jr., J.B.2
  • 23
  • 25
    • 0024584020 scopus 로고
    • Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells
    • (1989) J. Exp. Med. , vol.169 , pp. 1543
    • Stuehr, D.J.1    Nathan, C.F.2
  • 32
    • 0025753367 scopus 로고
    • Molecular basis of "suppressor" macrophages. Arginine metabolism via the nitric oxide synthetase pathway
    • (1991) J. Immunol. , vol.146 , pp. 2719
    • Mills, C.D.1
  • 43
    • 0023706894 scopus 로고
    • Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production
    • (1988) J. Immunol. , vol.141 , pp. 2407
    • Ding, A.H.1    Nathan, C.F.2    Stuehr, D.J.3
  • 46
    • 0023881236 scopus 로고
    • Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy
    • (1988) Cancer Res. , vol.48 , pp. 759
    • Pegg, A.E.1
  • 48
    • 0021963544 scopus 로고
    • Bacterial lipopolysaccharide induction of ornithine decarboxylase in the macrophage-like cell line RAW264, requirement of an inducible soluble factor
    • (1985) J. Cell. Physiol. , vol.122 , pp. 215
    • Taffet, S.M.1    Haddox, M.K.2
  • 57
    • 0019434576 scopus 로고
    • Activation of mouse macrophages for tumor cell killing. I. Quantitative analysis of interactions between lymphokine and lipopolysaccharide
    • (1981) J. Immunol. , vol.126 , pp. 1863
    • Pace, J.L.1    Russell, S.W.2
  • 72
  • 77
    • 0027378498 scopus 로고
    • Infection of murine macrophages with Toxoplasma gondii is associatedwith release of transforming growth factor beta and downregulation of expression of tumor necrosis factor receptors
    • (1993) Infect. Immun. , vol.61 , pp. 4126
    • Bermudez, L.E.1    Covaro, G.2    Remington, J.3
  • 78
    • 0027300313 scopus 로고
    • Production of transforming growth factor-beta by Mycobacterium avium-infected human macrophages is associated with unresponsiveness to IFN-gamma
    • (1993) J. Immunol. , vol.150 , pp. 1838
    • Bermudez, L.E.1
  • 90
    • 84873760212 scopus 로고
    • The specific amino acid requirements of a mammalian cell (strain 1) in tissue culture
    • (1954) J. Biol. Chem. , vol.214 , pp. 839
    • Eagle, H.1
  • 96
    • 0033535039 scopus 로고    scopus 로고
    • Arginase II downregulates nitric oxide (NO) production and prevents NO-mediated apoptosis in murine macrophage-derived RAW 264.7 cells
    • (1999) J. Cell. Biol. , vol.144 , pp. 427
    • Gotoh, T.1    Mori, M.2
  • 105
    • 0032534683 scopus 로고    scopus 로고
    • Intrinsic defects in macrophage IL-12 production associated with immune dysfunction in the MRL/++ and New Zealand Black/White F1 lupus-prone mice and the Leishmania major-susceptible BALB/c strain
    • (1998) J. Immunol. , vol.161 , pp. 6878
    • Alleva, D.G.1    Kaser, S.B.2    Beller, D.I.3
  • 108
    • 0025864926 scopus 로고
    • Tumor necrosis factor and granulocyte macrophage-colony stimulating factor stimulate human macrophages to restrict growth of virulent Mycobacterium avium and to kill avirulent M. avium, killing effector mechanism depends on the generation of reactive nitrogen intermediates
    • (1991) J. Leukoc. Biol. , vol.49 , pp. 380
    • Denis, M.1
  • 116
  • 125
    • 0024534407 scopus 로고
    • Spontaneous recovery of rats from experimental allergic encephalomyelitis is dependent on regulation of the immune system by endogenous adrenal corticosteroids
    • (1989) J. Exp. Med. , vol.169 , pp. 431
    • MacPhee, I.A.1    Antoni, F.A.2    Mason, D.W.3
  • 129
    • 0034177876 scopus 로고    scopus 로고
    • Regulation of the RON receptor tyrosine kinase expression in macrophages: Blocking the RON gene transcription by endotoxin-induced nitric oxide
    • (2000) J. Immunol. , vol.164 , pp. 3815
    • Wang, M.H.1    Fung, H.L.2    Chen, Y.Q.3
  • 131
    • 0028900805 scopus 로고
    • Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase
    • (1995) J. Exp. Med. , vol.181 , pp. 559
    • Corbett, J.A.1    McDaniel, M.L.2
  • 135
    • 0023492577 scopus 로고
    • Induction of interleukin 1 secretion and of tumoricidal activity in macrophages are not closely related phenomena
    • (1987) Eur. J. Immunol. , vol.17 , pp. 1665
    • Keller, R.1    Keist, R.2
  • 146
    • 0022891340 scopus 로고
    • Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • (1986) N. Engl. J. Med. , vol.315 , pp. 1650
    • Dvorak, H.F.1
  • 159
    • 0025886953 scopus 로고
    • Adoptive T cell therapy of tumors, mechanisms operative in the recognition and elimination of tumor cells
    • (1991) Adv. Immunol. , vol.49 , pp. 281
    • Greenberg, P.D.1
  • 162
    • 0017823225 scopus 로고
    • Macrophage requirement for growth of a murine fibrosarcoma
    • (1978) Br. J. Cancer , vol.37 , pp. 1086
    • Evans, R.1
  • 163
    • 0015489740 scopus 로고
    • Molecular repair, wound healing, and carcinogenesis: Tumor production a possible overhealing?
    • (1972) Adv. Cancer Res. , vol.16 , pp. 181
    • Haddow, A.1
  • 180
    • 0033557291 scopus 로고    scopus 로고
    • Macrophage microbicidal mechanisms in vivo, reactive nitrogen versus oxygen intermediates in the killing of intracellular visceral Leishmania donovani
    • (1999) J. Exp. Med. , vol.189 , pp. 741
    • Murray, H.W.1    Nathan, C.F.2
  • 185
    • 0032934731 scopus 로고    scopus 로고
    • In vivo blockage of nitric oxide with aminoguanidine inhibits immunosuppression induced by an attenuated strain of Salmonella typhimurium, potentiates Salmonella infection, and inhibits macrophage and polymorphonuclear leukocyte influx into the spleen
    • (1999) Infect. Immun. , vol.67 , pp. 891
    • MacFarlane, A.S.1    Schwacha, M.G.2    Eisenstein, T.K.3
  • 196
  • 197
    • 0033559312 scopus 로고    scopus 로고
    • Human immunodeficiency virus-1-infected macrophages induce inducible nitric oxide synthase and nitric oxide (NO) production in astrocytes: Astrocytic NO as a possible mediator of neural damage in acquired immunodeficiency syndrome
    • (1999) Blood , vol.93 , pp. 1843
    • Hori, K.1    Burd, P.R.2    Furuke, K.3    Kutza, J.4    Weih, K.A.5    Clouse, K.A.6
  • 200
    • 0343517098 scopus 로고    scopus 로고
    • Interleukin-12 (IL-12) enhancement of the cellular immune response against human immunodeficiency virus type 1 env antigen in a DNA prime/vaccinia virus boost vaccine regimen is time and dose dependent: Suppressive effects of IL-12 boost are mediated by nitric oxide
    • (2000) J. Virol. , vol.74 , pp. 6278
    • Gherardi, M.M.1    Ramirez, J.C.2    Esteban, M.3
  • 208
    • 0034601012 scopus 로고    scopus 로고
    • Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis
    • (2000) J. Exp. Med. , vol.192 , pp. 123
    • Chu, C.Q.1    Wittmer, S.2    Dalton, D.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.