Enhancing effect of oxygen radical scavengers on murine macrophage anticryptococcal activity through production of nitric oxide

Clinical and Experimental Immunology

Volumn 103, Issue 3, 1996, Pages 436-441

  Tohyama, M ^a   Kawakami, K ^a   Futenma, M ^a   Saito, A ^a  

^a UNIVERSITY OF THE RYUKYUS   (Japan)

Author keywords

Cryptococcus neoformans; Interferon gamma; Macrophages; Nitric oxide; Oxygen radical scavengers; Superoxide

Indexed keywords

CATALASE; N(G) METHYLARGININE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; RECOMBINANT GAMMA INTERFERON; SUPEROXIDE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANTIFUNGAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; FEMALE; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0029881756     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.1996.tb08299.x     Document Type: Article

References (38)

1. Walker L, Lowries DB. Killing of Mycobacterium microti by immunologically activated macrophages. Nature 1981; 293:69-71.
2. Chan J, Xing Y, Magliozzo RS, Bloom BR. Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages. J Exp Med 1992; 175: 1111-22.
3. Murray HW, Rubin SM, Carriero SM, Harris AM, Jaffee EA. Human mononuclear phagocyte antiprotozoal mechanisms: oxygen-dependent vs. oxygen-independent activity against intracellular Toxoplasma gondii. J Immunol 1985; 134:1982-8.
4. Rothermel CD, Rubin BY, Jaffe EA, Murray HW. Oxygen-independent inhibition of intracellular Chlamydia psittaci growth by human monocytes and interferon-γ-activated macrophages. J Immunol 1986; 137:689-92.
5. Hibbs JB Jr, Taintor RR, Vavrin Z. Macrophage cytotoxicity: role for L-arginine deaminase and amino nitrogen oxidation to nitrite. Science 1987; 197:473-6.
6. Denis M. Interferon-gamma-treated macrophages inhibit growth of tubercle bacilli via the generation of reactive nitrogen intermediates. Cell Immunol 1991; 132:150-7.
7. Adams LB, Franzblau SG, Vavrin Z, Hibbs JB Jr, Krahenbuhl JL. L-arginine-dependent macrophage effector functions inhibit metabolic activity of Mycobacterium leprae. J immunol 1991; 147: 1642-6.
8. Granger DL, Hibbs JB Jr, Perfect JR, Durack DT. Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages. J Clin Invest 1990; 85:264-7.
9. Liew FY, Millott S, Parkinson C, Palmer RM, Moncada S. Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-argnine. J Immunol 1990; 144:4794-7.
10. James SL, Glaven J. Macrophage cytotoxity against schistosomula of Schistosoma mansoni involves arginine-dependent production of reactive nitrogen intermediates. J Immunol 1989; 143:4208-12.
11. Langermans JAM, Van der Hulst MEB, Nibbering PH, Hiemstra PS, Fransen L, Van Furth R. IFN-γ-induced L-arginine-dependent toxoplasmatic activity in murine peritoneal macrophages is mediated by endogenous tumor necrosis factor-α. J Immunol 1992; 148:568-74.
12. Gazzinelli RT, Oswald IP, Hieny S, James SL, Sher A. The microbicidal activity of interferon-gamma-treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-beta. Eur J Immunol 1992; 22:2501-6.
13. Stuehr DJ, Marletta MA. Induction of nitrite/nitrate synthesis in murine macrophages by BCG infection, lymphokines or interferon-γ. J immunol 1987; 139:518-25.
14. Desai SD, Birdi TJ, Antia NH. Correlation between macrophage activation and bactericidal function and Mycobacterium leprae antigen presentation in macrophages of leprosy patients and normal individuals. Infect Immun 1989; 57:1311-7.
15. Kawakami K, Kohno S, Kadota J et al. T cell-dependent activation of macrophages and enhancement of their phagocytic activity in the lungs of mice inoculated with heat-killed Cryptococcus neoformans: involvement of IFN-γ and its protective effect against cryptococcal infection. Microbiol Immunol 1995; 39:135-43.
16. Nacy CA, Fortier AH, Meltzer MS, Buchmeier NA, Schreiber RD. Macrophage activation to kill Leishmania major activation of macrophages for intracellular destruction of amastiogotes can be induced by both recombinant interferon-γ and non-interferon lymphokines. J Immunol 1985; 135:3505-11.
17. Esparza I, Mannel D, Ruppel A, Falk W, Krammer PH. Interferon γ and lymphotoxin or tumor necrosis factor act synergistically to induce macrophage killing of tumor cells and schistosomula of Schistosoma mansoni. J Exp Med 1987; 166:589-94.
18. Reed SG, Nathan CF, Pihl DL, Rodricks P, Shanebeck K, Conlon PJ, Grabstein KH. Recombinant granulocyte/macrophage colony-stimulating factor activates macrophages to inhibit Trypanosoma cruzi and release hydrogen peroxide. J Exp Med 1987; 166:1734-46.
19. Stevens DA. Fungal infections in AIDS patients. Br J Clin Practice 1990; 44 (Suppl. 1): 11-22.
20. Murphy JW. Cryptococcosis. In: Cox RA, ed. Immunology of fungal diseases. Boca Raton: CRC Press, 1989: 93-138.
21. Brummer E, Stevens D. Anticryptococcal activity of macrophages: role of mouse strain, C5, contact, and L-arginine. Cell Immunol 1994; 157:1-10.
22. Stuehr, DJ, Nathan CF. Nitric oxide: a macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. J Exp med 1989; 169:1543-55.
23. Alspaugh JA, Granger DL. Inhibition of Cryptococcus neoformans replication by nitrogen oxides supports the role of these molecules as effectors of macrophages-mediated cytostasis. Infect Immun 1991; 59:2291-6.
24. Jacobson ES, Tinnell SB. Antioxidant function of fungal melanin. J Bacteriol 1993; 175:7102-4.
25. Densen P, Clark RA, Nauseef WM. Granulocytic phagocytes. In: Mansel GL, Bennet JE., Dolin R, eds. Principle and practice of infectious diseases. New York: Churchill Livingstone Inc, 1995: 78-101.
26. Klein J. Defence reactions mediated by phagocytes. In: Klein J, ed. Immunology, Oxford: Blackwell Scientific Publications Inc, 1990: 311-34.
27. Flesch IEA, Kaufmann SHE. Attempts to characterize the mechanisms involved in mycobacterial growth inhibition by gamma-interferon-activaled bone marrow macrophages. Infect Immun 1988; 56:1464-9.
28. Murray HW, Cartelli DM. Killing intracellular Leishmania donovani by human mononuclear phagocytes: evidence for oxygen-dependent and -independent leishmaniacidal activity. J. Clin Invest 1983; 72:32-44.
29. Scott P, James S, Sher A. The respiratory burst is not required for killing of intracellular and extracellular parasites by a lymphokine-activated macrophage cell line. Eur J Immunol 1985; 15:553-8.
30. Kwon-Chung KJ, Polacheck I, Popkin TJ. Melanin-lacking mutants of Cryptococcus neoformans and their virulence for mice. J. Bacteriol 1982; 150:1414-21.
31. McCall TB, Boughton-Smith NK, Palmer RMJ, Whittle BJR, Moncada S. Synthesis of nitric oxide from L-arginine by neutrophils: release and interaction with superoxide anion. Biochem J 1989; 261:293-6.
32. Albina JE, Mills CD, Henry WL Jr, Caldwell MD. Regulation of macrophage physiology by L-arginine: role of the oxidative L-arginine deiminase pathway. J Immunol 1989; 143:3641-6.
33. Carreras MC, Pargament GA, Catz SD, Poderoso JJ, Boveris A. Kinetics of nitric oxide and hydrogen peroxide production and formation of peroxynitrite during the respiratory burst of human neutrophils. FEBS Lett 1994; 341:65-68.
34. Gryglewski RJ, Palmer RMJ, Moncada S. Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature 1986; 320:454-6.
35. Zhu L, Gunn C, Beckman JS. Bactericidal activity of peroxynitrite. Arch Biochem Biophys 1992; 298:425-7.
36. Denicola A, Rubbo H, Rodriguez D, Radi R. Peroxynitrite-mediated cytotoxicity to Trypanosoma cruzi. Arch Bikochem Biophys 1993; 304:279-86.
37. Clancy RM, Leszczynska-Piziak J, Abramson SB. Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase. J Clin Invest 1992; 90:1116-21.
38. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J 1992; 6:3051-64.