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Volumn 161, Issue 9, 1998, Pages 4950-4959

Activation of the RON receptor tyrosine kinase inhibits inducible nitric oxide synthase (iNOS) expression by murine peritoneal exudate macrophages: Phosphatidylinositol-3 kinase is required for RON-mediated inhibition of iNOS expression

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; NITRIC OXIDE SYNTHASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE;

EID: 0032211131     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (78)

References (55)
  • 1
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada, S., R. M. J. Palmer, and E. A. Higgs. 1991. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 43:109.
    • (1991) Pharmacol. Rev. , vol.43 , pp. 109
    • Moncada, S.1    Palmer, R.M.J.2    Higgs, E.A.3
  • 2
    • 0028270719 scopus 로고
    • Regulation of biosynthesis of nitric oxide
    • Nathan, C., and Q.-W. Xie. 1994. Regulation of biosynthesis of nitric oxide. J. Biol. Chem. 269:13725.
    • (1994) J. Biol. Chem. , vol.269 , pp. 13725
    • Nathan, C.1    Xie, Q.-W.2
  • 3
    • 0027244724 scopus 로고
    • Inflammation, immunoregulation, and inducible nitric oxide synthase
    • Nussler, A. K., and T. R. Billiar. 1993. Inflammation, immunoregulation, and inducible nitric oxide synthase. J. Leukocyte Biol. 54:171.
    • (1993) J. Leukocyte Biol. , vol.54 , pp. 171
    • Nussler, A.K.1    Billiar, T.R.2
  • 4
    • 0027939931 scopus 로고
    • Role of transcription factor NF-κB/Rel in induction of nitric oxide synthase
    • Xie, Q.-W., Y. Kashiwabara, and C. Nathan. 1994. Role of transcription factor NF-κB/Rel in induction of nitric oxide synthase. J. Biol. Chem. 269:4705.
    • (1994) J. Biol. Chem. , vol.269 , pp. 4705
    • Xie, Q.-W.1    Kashiwabara, Y.2    Nathan, C.3
  • 5
    • 0030481581 scopus 로고    scopus 로고
    • The rel subunit of NF-κB-like transcription factors is a positive and negative regulator of macrophage gene expression: Distinct roles for Rel in different macrophage populations
    • Grigoriadis, G., Y. Zhan, R. J. Grumont, D. Metcalf, E. Handman, C. Cheers, and S. Gerondakis. 1996. The rel subunit of NF-κB-like transcription factors is a positive and negative regulator of macrophage gene expression: distinct roles for Rel in different macrophage populations. EMBO J. 15:7099.
    • (1996) EMBO J. , vol.15 , pp. 7099
    • Grigoriadis, G.1    Zhan, Y.2    Grumont, R.J.3    Metcalf, D.4    Handman, E.5    Cheers, C.6    Gerondakis, S.7
  • 6
    • 0028106830 scopus 로고
    • Role of interferon regulatory factor 1 in induction of nitric oxide synthase
    • Martin, E., C. Nathan, and Q.-W. Xie, 1994. Role of interferon regulatory factor 1 in induction of nitric oxide synthase. J. Exp. Med. 180:977.
    • (1994) J. Exp. Med. , vol.180 , pp. 977
    • Martin, E.1    Nathan, C.2    Xie, Q.-W.3
  • 8
    • 0023796162 scopus 로고
    • Interferon-γ and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages
    • Drapier, J.-C., J. Weitzerbin, and J. B. Hibbs, Jr. 1988. Interferon-γ and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages. Eur. J. Immunol. 18:1587.
    • (1988) Eur. J. Immunol. , vol.18 , pp. 1587
    • Drapier, J.-C.1    Weitzerbin, J.2    Hibbs Jr., J.B.3
  • 9
    • 0028886258 scopus 로고
    • Nitric oxide synthesis contributes to IL-2-induced anti-tumor responses against intraperitoneal Meth A tumor
    • Yim, C. Y., J. R. McGregor, O. D. Kwon, N. R. Bastian, M. Rees, M. Mon, J. B. Hibbs, and W. E. Samlowski. 1995. Nitric oxide synthesis contributes to IL-2-induced anti-tumor responses against intraperitoneal Meth A tumor. J. Immunol. 155:4382.
    • (1995) J. Immunol. , vol.155 , pp. 4382
    • Yim, C.Y.1    McGregor, J.R.2    Kwon, O.D.3    Bastian, N.R.4    Rees, M.5    Mon, M.6    Hibbs, J.B.7    Samlowski, W.E.8
  • 10
    • 0027459588 scopus 로고
    • Expression of the nitric oxide synthase gene in macrophages activated for tumor cell killing
    • Lorsbach, R. B., W. J. Murphy, C. J. Lowenstein, S. H. Snyder, and S. W. Russell. 1993. Expression of the nitric oxide synthase gene in macrophages activated for tumor cell killing. J. Biol. Chem. 268:1908.
    • (1993) J. Biol. Chem. , vol.268 , pp. 1908
    • Lorsbach, R.B.1    Murphy, W.J.2    Lowenstein, C.J.3    Snyder, S.H.4    Russell, S.W.5
  • 11
    • 0027231742 scopus 로고
    • Nitric oxide-mediated apoptosis in murine peritoneal macrophages
    • Albina, J. E., S. Cui, R. B. Mateo, and J. S. Reichner. 1993. Nitric oxide-mediated apoptosis in murine peritoneal macrophages. J. Immunol. 150:5080.
    • (1993) J. Immunol. , vol.150 , pp. 5080
    • Albina, J.E.1    Cui, S.2    Mateo, R.B.3    Reichner, J.S.4
  • 13
    • 0026563728 scopus 로고
    • Nitric oxide: A pathogenetic factor in autoimmunity
    • Kolb, H., and C. Kolb-Bachofen. 1992. Nitric oxide: a pathogenetic factor in autoimmunity. Immunol. Today 13:157.
    • (1992) Immunol. Today , vol.13 , pp. 157
    • Kolb, H.1    Kolb-Bachofen, C.2
  • 16
    • 0027203305 scopus 로고
    • Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor-β
    • Vodovotz, Y., C. Bogdan, J. Paik, Q.-W. Xie, and C. Nathan. 1993. Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor-β. J. Exp. Med. 178:605.
    • (1993) J. Exp. Med. , vol.178 , pp. 605
    • Vodovotz, Y.1    Bogdan, C.2    Paik, J.3    Xie, Q.-W.4    Nathan, C.5
  • 17
    • 0027980203 scopus 로고
    • Mechanism of suppression of nitric oxide synthase expression by interleukin 4 in primary mouse macrophages
    • Bogdan, C., Y. Vodovotz, J. Paik, Q.-W. Xie, and C. Nathan, 1994. Mechanism of suppression of nitric oxide synthase expression by interleukin 4 in primary mouse macrophages. J. Leukocyte Biol. 55:227.
    • (1994) J. Leukocyte Biol. , vol.55 , pp. 227
    • Bogdan, C.1    Vodovotz, Y.2    Paik, J.3    Xie, Q.-W.4    Nathan, C.5
  • 18
    • 0030587817 scopus 로고    scopus 로고
    • Recombinant human IL-11 attenuates the inflammatory response through down-regulation of proinflammatory cytokine release and nitric oxide production
    • Trepicchio, W. L., M. Bozza, G. Pedneault, and A. J. Dorner. 1996. Recombinant human IL-11 attenuates the inflammatory response through down-regulation of proinflammatory cytokine release and nitric oxide production. J. Immunol. 157: 3627.
    • (1996) J. Immunol. , vol.157 , pp. 3627
    • Trepicchio, W.L.1    Bozza, M.2    Pedneault, G.3    Dorner, A.J.4
  • 19
    • 0025756806 scopus 로고
    • Macrophage stimulating protein: Purification, partial amino acid sequence, and cellular activity
    • Skeel, A., T. Yoshimura, S. Showalter, S. Tanaka, E. Appella, and E. J. Leonard. 1991. Macrophage stimulating protein: purification, partial amino acid sequence, and cellular activity. J. Exp. Med. 173:1227.
    • (1991) J. Exp. Med. , vol.173 , pp. 1227
    • Skeel, A.1    Yoshimura, T.2    Showalter, S.3    Tanaka, S.4    Appella, E.5    Leonard, E.J.6
  • 20
    • 0028139182 scopus 로고
    • Identification of the RON gene product as the receptor for the human macrophage stimulating protein
    • Wang, M.-H., C. Ronsin, M.-C. Gesnel, L. Coupey, A. Skeel, E. J. Leonard, and R. Breathnach 1994. Identification of the RON gene product as the receptor for the human macrophage stimulating protein. Science 266:117.
    • (1994) Science , vol.266 , pp. 117
    • Wang, M.-H.1    Ronsin, C.2    Gesnel, M.-C.3    Coupey, L.4    Skeel, A.5    Leonard, E.J.6    Breathnach, R.7
  • 22
    • 0028352123 scopus 로고
    • Macrophage stimulating protein inhibits induction of nitric oxide production by endotoxin or cytokine stimulated mouse macrophages
    • Wang, M.-H., W. G. Cox, T. Yoshimura, L. A. Sheffler, A. Skeel, and E. J. Leonard. 1994. Macrophage stimulating protein inhibits induction of nitric oxide production by endotoxin or cytokine stimulated mouse macrophages. J. Biol. Chem. 269: 14027.
    • (1994) J. Biol. Chem. , vol.269 , pp. 14027
    • Wang, M.-H.1    Cox, W.G.2    Yoshimura, T.3    Sheffler, L.A.4    Skeel, A.5    Leonard, E.J.6
  • 23
    • 0017171856 scopus 로고
    • A serum protein that stimulates macrophage movement, chemotaxis and spreading
    • Leonard, E. J., and A. Skeel. 1976. A serum protein that stimulates macrophage movement, chemotaxis and spreading. Exp. Cell Res. 102:434.
    • (1976) Exp. Cell Res. , vol.102 , pp. 434
    • Leonard, E.J.1    Skeel, A.2
  • 24
    • 0027204250 scopus 로고
    • Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins, and locates the MSP gene on chromosome 3
    • Yoshimura T., N. Yuhki, M.-H. Wang, A. Skeel, and E. J. Leonard. 1993. Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins, and locates the MSP gene on chromosome 3. J. Biol. Chem. 268:15461.
    • (1993) J. Biol. Chem. , vol.268 , pp. 15461
    • Yoshimura, T.1    Yuhki, N.2    Wang, M.-H.3    Skeel, A.4    Leonard, E.J.5
  • 25
    • 0001599594 scopus 로고
    • Amino-acid sequence of activation cleavage site in plasminogen: Homology with "pro" part of prothrombin
    • Sottrup-Jensen, L., M. Zajdel, H. Claeys, T. E. Petersen, and S. Magnusson. 1992. Amino-acid sequence of activation cleavage site in plasminogen: homology with "pro" part of prothrombin. Proc. Natl. Acad. Sci. USA 72:2577.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.72 , pp. 2577
    • Sottrup-Jensen, L.1    Zajdel, M.2    Claeys, H.3    Petersen, T.E.4    Magnusson, S.5
  • 26
    • 0027742111 scopus 로고
    • Hepatocyte growth factor scatter factor and its receptor, the c-met proto-oncogene product
    • Rubin, J. S., D. P. Bottaro, and S. A. Aaronson. 1993. Hepatocyte growth factor scatter factor and its receptor, the c-met proto-oncogene product. Biochim. Biophys. Acta 1155:357.
    • (1993) Biochim. Biophys. Acta , vol.1155 , pp. 357
    • Rubin, J.S.1    Bottaro, D.P.2    Aaronson, S.A.3
  • 27
    • 0025938869 scopus 로고
    • Characterization of the DNF15S2 locus on human chromosome 3: Identification of a gene coding for four kringle domains with homology to hepatocyte growth factor
    • Han, S., L. A. Stuart, and S. J. Friezner Degen. 1993. Characterization of the DNF15S2 locus on human chromosome 3: identification of a gene coding for four kringle domains with homology to hepatocyte growth factor. Biochemistry 30: 9768.
    • (1993) Biochemistry , vol.30 , pp. 9768
    • Han, S.1    Stuart, L.A.2    Friezner Degen, S.J.3
  • 28
    • 0027248125 scopus 로고
    • Hepatocyte-specific expression of the mouse hepatocyte growth factor-like protein
    • Bezerra, J. A., D. P. Witte, B. J. Aronow, and S. J. Friezner Degen. 1993. Hepatocyte-specific expression of the mouse hepatocyte growth factor-like protein. Hepatology 18:394.
    • (1993) Hepatology , vol.18 , pp. 394
    • Bezerra, J.A.1    Witte, D.P.2    Aronow, B.J.3    Friezner Degen, S.J.4
  • 29
    • 0030056374 scopus 로고    scopus 로고
    • Proteolytic cleavage and activation of pro-macrophage stimulating protein by resident peritoneal macrophage membrane proteases
    • Wang, M.-H., A. Skeel, and E. J. Leonard. 1996. Proteolytic cleavage and activation of pro-macrophage stimulating protein by resident peritoneal macrophage membrane proteases. J. Clin. Invest. 97:72.
    • (1996) J. Clin. Invest. , vol.97 , pp. 72
    • Wang, M.-H.1    Skeel, A.2    Leonard, E.J.3
  • 31
    • 0027957058 scopus 로고
    • Proteolytic conversion of single chain precursor macrophage stimulating protein to a biologically active heterodimer by contact enzymes of the coagulation cascade
    • Wang, M.-H., T. Yoshimura, A. Skeel, and E. J. Leonard. 1994. Proteolytic conversion of single chain precursor macrophage stimulating protein to a biologically active heterodimer by contact enzymes of the coagulation cascade. J. Biol. Chem. 269:3436.
    • (1994) J. Biol. Chem. , vol.269 , pp. 3436
    • Wang, M.-H.1    Yoshimura, T.2    Skeel, A.3    Leonard, E.J.4
  • 32
    • 0028300590 scopus 로고
    • Proteolytic activation of single chain precursor macrophage stimulating protein by members of tissue kallikrein family: Nerve growth factor-γ and epidermal growth factor binding protein
    • Wang, M.-H., S. L. Gonias, A. Skeel, B. B. Wolf, T. Yoshimura, and E. J. Leonard. 1994. Proteolytic activation of single chain precursor macrophage stimulating protein by members of tissue kallikrein family: nerve growth factor-γ and epidermal growth factor binding protein. J. Biol. Chem. 269:13806.
    • (1994) J. Biol. Chem. , vol.269 , pp. 13806
    • Wang, M.-H.1    Gonias, S.L.2    Skeel, A.3    Wolf, B.B.4    Yoshimura, T.5    Leonard, E.J.6
  • 33
    • 0027318311 scopus 로고
    • A novel putative receptor protein tyrosine kinase of the met family
    • Ronsin, C., F. Muscatelli, M. G. Matter, and R. Breathnach. 1993. A novel putative receptor protein tyrosine kinase of the met family. Oncogene 8:1195.
    • (1993) Oncogene , vol.8 , pp. 1195
    • Ronsin, C.1    Muscatelli, F.2    Matter, M.G.3    Breathnach, R.4
  • 34
    • 1242348060 scopus 로고
    • Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth factor receptors
    • Park, M., M. Dean, K. Kaul, M. Braun, M. A. Gonda, and G. Vande Woude. 1987. Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth factor receptors. Proc. Natl. Acad. Sci. USA 84:6379.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 6379
    • Park, M.1    Dean, M.2    Kaul, K.3    Braun, M.4    Gonda, M.A.5    Vande Woude, G.6
  • 35
    • 0028206124 scopus 로고
    • Molecular cloning of a novel receptor tyrosine kinase gene, STK, derived from enriched hematopoietic stem cells
    • Iwama, A., K. Okano, T. Sudo, Y. Matsuda, and T. Suda. 1994. Molecular cloning of a novel receptor tyrosine kinase gene, STK, derived from enriched hematopoietic stem cells. Blood 83:3160.
    • (1994) Blood , vol.83 , pp. 3160
    • Iwama, A.1    Okano, K.2    Sudo, T.3    Matsuda, Y.4    Suda, T.5
  • 36
    • 0029027666 scopus 로고
    • The murine STK gene product, a transmembrane protein tyrosine kinase, is a specific cell membrane receptor for macrophage stimulating protein
    • Wang, M.-H., A. Iwama, A. Skeel, T. Suda, and E. J. Leonard. 1995. The murine STK gene product, a transmembrane protein tyrosine kinase, is a specific cell membrane receptor for macrophage stimulating protein. Proc Natl. Acad. Sci. USA 92:3933.
    • (1995) Proc Natl. Acad. Sci. USA , vol.92 , pp. 3933
    • Wang, M.-H.1    Iwama, A.2    Skeel, A.3    Suda, T.4    Leonard, E.J.5
  • 37
    • 0028874987 scopus 로고
    • Terminal differentiation of murine resident peritoneal macrophages is characterized by expression of the STK protein tyrosine kinase, a receptor for macrophage stimulating protein
    • Iwama, A., M.-H. Wang, N. Yamaguchi, N. Ohno, K. Okano, T. Sudo, M. Takeya, F. Gervais, C. Morissette, E. J. Leonard, and T. Suda. 1995. Terminal differentiation of murine resident peritoneal macrophages is characterized by expression of the STK protein tyrosine kinase, a receptor for macrophage stimulating protein. Blood 86:3394.
    • (1995) Blood , vol.86 , pp. 3394
    • Iwama, A.1    Wang, M.-H.2    Yamaguchi, N.3    Ohno, N.4    Okano, K.5    Sudo, T.6    Takeya, M.7    Gervais, F.8    Morissette, C.9    Leonard, E.J.10    Suda, T.11
  • 38
    • 0028326807 scopus 로고
    • Action and target cell specificity of human macrophage stimulating protein (MSP)
    • Skeel, A., and E. J. Leonard. 1994. Action and target cell specificity of human macrophage stimulating protein (MSP). J. Immunol. 152:4618.
    • (1994) J. Immunol. , vol.152 , pp. 4618
    • Skeel, A.1    Leonard, E.J.2
  • 39
    • 0029838319 scopus 로고    scopus 로고
    • Requirement of phosphatidylinositol-3 kinase for epithelial cell migration activated by human macrophage stimulating protein
    • Wang, M.-H., F. A. Montero-Julian, I. Dauny, and E. J. Leonard. 1996. Requirement of phosphatidylinositol-3 kinase for epithelial cell migration activated by human macrophage stimulating protein. Oncogene 13:2167.
    • (1996) Oncogene , vol.13 , pp. 2167
    • Wang, M.-H.1    Montero-Julian, F.A.2    Dauny, I.3    Leonard, E.J.4
  • 40
    • 0029959639 scopus 로고    scopus 로고
    • STK/RON receptor tyrosine kinase mediates both apoptotic and growth signals via the multifunctional docking site conserved among the HGF receptor family
    • Iwama, A., N. Yamaguchi, and T. Suda 1996. STK/RON receptor tyrosine kinase mediates both apoptotic and growth signals via the multifunctional docking site conserved among the HGF receptor family. EMBO J. 15:5866.
    • (1996) EMBO J. , vol.15 , pp. 5866
    • Iwama, A.1    Yamaguchi, N.2    Suda, T.3
  • 41
    • 0010870133 scopus 로고    scopus 로고
    • Increased interferon-γ-mediated nitric oxide production, inflammation and susceptibility to endotoxic shock in mice lacking the STK receptor tyrosine kinase
    • Correll, P. H., A. Iwama, S. Tondat, G. Mayrhofer, T. Suda, and A. Bernstein. 1997. Increased interferon-γ-mediated nitric oxide production, inflammation and susceptibility to endotoxic shock in mice lacking the STK receptor tyrosine kinase. Genes Funct. 1:1.
    • (1997) Genes Funct. , vol.1 , pp. 1
    • Correll, P.H.1    Iwama, A.2    Tondat, S.3    Mayrhofer, G.4    Suda, T.5    Bernstein, A.6
  • 43
    • 0026729267 scopus 로고
    • Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme
    • Lowenstein, C. J., C. S. Glatt, D. S. Bredt, and S. H. Snyder. 1992. Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme. Proc. Natl. Acad. Sci. USA 89:6711.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6711
    • Lowenstein, C.J.1    Glatt, C.S.2    Bredt, D.S.3    Snyder, S.H.4
  • 45
    • 0029916506 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor-4 is responsible for the liver-specific expression of the gene coding for hepatocyte growth factor-like protein
    • Waltz, S. E., F. K. Gould, E. L. Air, S. A. McDowell, and S. J. F. Degen. 1996. Hepatocyte nuclear factor-4 is responsible for the liver-specific expression of the gene coding for hepatocyte growth factor-like protein. J. Biol. Chem. 271:9024.
    • (1996) J. Biol. Chem. , vol.271 , pp. 9024
    • Waltz, S.E.1    Gould, F.K.2    Air, E.L.3    McDowell, S.A.4    Degen, S.J.F.5
  • 46
    • 0028146616 scopus 로고
    • Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol-3 kinase
    • Okada, T., L. Sakuma, Y. Fukui, O. Hazeki, and M. Ui. 1994. Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol-3 kinase. J. Biol. Chem. 269:3563.
    • (1994) J. Biol. Chem. , vol.269 , pp. 3563
    • Okada, T.1    Sakuma, L.2    Fukui, Y.3    Hazeki, O.4    Ui, M.5
  • 47
    • 0029933168 scopus 로고
    • Macrophage-stimulating protein activates STK receptor tyrosine kinase on osteoclasts and facilitates bone resorption by osteoclast-like cells
    • Kurihara, N., A. Iwama, J. Katsumi, K. Ikeda, and T. Suda. 1994. Macrophage-stimulating protein activates STK receptor tyrosine kinase on osteoclasts and facilitates bone resorption by osteoclast-like cells. Blood 87:3704.
    • (1994) Blood , vol.87 , pp. 3704
    • Kurihara, N.1    Iwama, A.2    Katsumi, J.3    Ikeda, K.4    Suda, T.5
  • 48
    • 0029802366 scopus 로고    scopus 로고
    • Induction of met protooncogene (hepatocyte growth factor receptor) expression during human monocyte-macrophage differentiation
    • Chen, Q., M. C. DeFrances, and R. Zarnegar. 1996. Induction of met protooncogene (hepatocyte growth factor receptor) expression during human monocyte-macrophage differentiation. Cell Growth Differ. 7:821.
    • (1996) Cell Growth Differ. , vol.7 , pp. 821
    • Chen, Q.1    Defrances, M.C.2    Zarnegar, R.3
  • 49
    • 0029097378 scopus 로고
    • Structure of the promoter for the human macrophage stimulating protein receptor gene
    • Del Gatto, F., E. Gilbert, C. Ronsin, and R. Breathnach. 1995. Structure of the promoter for the human macrophage stimulating protein receptor gene. Biochim. Biophys. Acta 1263:93.
    • (1995) Biochim. Biophys. Acta , vol.1263 , pp. 93
    • Del Gatto, F.1    Gilbert, E.2    Ronsin, C.3    Breathnach, R.4
  • 50
    • 0031298532 scopus 로고    scopus 로고
    • IL-11 regulates macrophage effect function through inhibition of nuclear factor-κB
    • Trepicchio, W. L., L. L. Wang, M. Bozza, and A. J. Dorner. 1997. IL-11 regulates macrophage effect function through inhibition of nuclear factor-κB. J. Immunol. 159:5661.
    • (1997) J. Immunol. , vol.159 , pp. 5661
    • Trepicchio, W.L.1    Wang, L.L.2    Bozza, M.3    Dorner, A.J.4
  • 52
    • 0028486018 scopus 로고
    • Phosphatidylinositol 3 kinase
    • Kapeller, R., and L. C. Cantley. 1994. Phosphatidylinositol 3 kinase. Bioassays 16:565.
    • (1994) Bioassays , vol.16 , pp. 565
    • Kapeller, R.1    Cantley, L.C.2
  • 53
    • 0030946256 scopus 로고    scopus 로고
    • Activation of phosphatidyl-inositol 3-kinase by interleukin 13: An inhibitory signal for inducible nitric oxide synthase expression in epithelial cell line Ht-29
    • Wright, K., S. G. Ward, G. Kolios, and J. Westwick. 1997. Activation of phosphatidyl-inositol 3-kinase by interleukin 13: an inhibitory signal for inducible nitric oxide synthase expression in epithelial cell line Ht-29. J. Biol. Chem. 272: 12626.
    • (1997) J. Biol. Chem. , vol.272 , pp. 12626
    • Wright, K.1    Ward, S.G.2    Kolios, G.3    Westwick, J.4
  • 54
    • 0031587403 scopus 로고    scopus 로고
    • Wortmannin, a specific inhibitor of phosphatidylinositol-3-kinase, enhances LPS-induced production from murine peritoneal macrophages
    • Park, Y. C., C. H. Lee, H. S. Kang, H. T. Chung, and H. D. Kim. 1997. Wortmannin, a specific inhibitor of phosphatidylinositol-3-kinase, enhances LPS-induced production from murine peritoneal macrophages. Biochem. Biophys. Res. Commun. 240:692.
    • (1997) Biochem. Biophys. Res. Commun. , vol.240 , pp. 692
    • Park, Y.C.1    Lee, C.H.2    Kang, H.S.3    Chung, H.T.4    Kim, H.D.5
  • 55
    • 0028884033 scopus 로고
    • PD098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
    • Alessi, D. R., A. Cuenda, P. Cohen, D. T. Dudley, and A. R. Saltiel. 1995. PD098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270:27489.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27489
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5


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