메뉴 건너뛰기




Volumn 41, Issue , 2001, Pages 53-77

Tumor cell death induced by topoisomerase-targeting drugs

Author keywords

Apoptosis; Camptothecin; SUMO; Topoisomerase; Ubiquitin

Indexed keywords

9 AMINO 20 CAMPTOTHECIN; CAMPTOTHECIN; CAMPTOTHECIN DERIVATIVE; DNA TOPOISOMERASE; DNA TOPOISOMERASE INHIBITOR; IRINOTECAN; PROTEASOME; TOPOTECAN; UBIQUITIN; UNCLASSIFIED DRUG;

EID: 0035029153     PISSN: 03621642     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.pharmtox.41.1.53     Document Type: Review
Times cited : (493)

References (159)
  • 21
    • 0027156630 scopus 로고
    • The specific interactions of HMG 1 and 2 with negatively supercoiled DNA are modulated by their acidic C-terminal domains and involve cysteine residues in their HMG 1/2 boxes
    • (1993) Biochemistry , vol.32 , pp. 3238-3248
    • Sheflin, L.G.1    Fucile, N.W.2    Spaulding, S.W.3
  • 40
    • 0029007898 scopus 로고
    • DNA topoisomerase II expression, stability, and phosphorylation in two VM-26-resistant human leukemic CEM sublines
    • (1995) Oncol. Res. , vol.7 , pp. 103-111
    • Chen, M.1    Beck, W.T.2
  • 41
    • 0028819988 scopus 로고
    • Selective use of an alternative stop codon and polyadenylation signal within intron sequences leads to a truncated topoisomerase II alpha messenger RNA and protein in human HL-60 leukemia cells selected for resistance to mitoxantrone
    • (1995) Cancer Res. , vol.55 , pp. 4962-4971
    • Harker, W.G.1    Slade, D.L.2    Parr, R.L.3    Holguin, M.H.4
  • 46
    • 0023924786 scopus 로고
    • Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin
    • (1988) Cancer Res. , vol.48 , pp. 1722-1726
    • Hsiang, Y.H.1    Liu, L.F.2
  • 61
    • 0034663907 scopus 로고    scopus 로고
    • Site specific topoisomerase I-mediated DNA cleavage induced by nogalamycin: A potential role of ligand-induced DNA bending at a distal site
    • (2000) Biochemistry , vol.39 , pp. 9928-9934
    • Sim, S.P.1    Pilch, D.S.2    Liu, L.F.3
  • 75
    • 0024420685 scopus 로고
    • Arrest of replication forks by drugstabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin
    • (1989) Cancer Res. , vol.49 , pp. 5077-5082
    • Hsiang, Y.H.1    Lihou, M.G.2    Liu, L.F.3
  • 83
    • 0032773824 scopus 로고    scopus 로고
    • The topoisomerase I poison camptothecin generates a Chk1-dependent DNA damage checkpoint signal in fission yeast
    • (1999) Yeast , vol.15 , pp. 821-828
    • Wan, S.1    Capasso, H.2    Walworth, N.C.3
  • 86
    • 0029738086 scopus 로고    scopus 로고
    • Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: Evidence for cell cycle-independent toxicity
    • (1996) J. Cell. Biol. , vol.134 , pp. 757-770
    • Morris, E.J.1    Geller, H.M.2
  • 89
    • 0032970814 scopus 로고    scopus 로고
    • Apoptotic response to camptothecin and 7-hydroxystaurosporine (UCN-01) in the 8 human breast cancer cell lines of the NCI Anticancer Drug Screen: Multifactorial relationships with topoisomerase I, protein kinase C, Bcl-2, p53, MDM-2 and caspase pathways
    • (1999) Int. J. Cancer , vol.82 , pp. 396-404
    • Nieves-Neira, W.1    Pommier, Y.2
  • 97
    • 0023070511 scopus 로고
    • Localization of specific topoisomerase I inter-actions within the transcribed region of active heat shock genes by using the inhibitor camptothecin
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 141-148
    • Gilmour, D.S.1    Elgin, S.C.2
  • 98
    • 0023614833 scopus 로고
    • Camptothecin-induced in vivo topoisomerase I cleavages in the transcriptionally active tyrosine aminotransferase gene
    • (1987) Cell , vol.50 , pp. 1109-1117
    • Stewart, A.F.1    Schutz, G.2
  • 101
    • 0029072716 scopus 로고
    • Camptothecin induction of a time- and concentration-dependent decrease of topoisomerase I and its implication in camptothecin activity
    • (1995) Mol. Pharmacol. , vol.47 , pp. 907-914
    • Beidler, D.R.1    Cheng, Y.C.2
  • 124
    • 0032541141 scopus 로고    scopus 로고
    • Topoisomerase II-mediated DNA cleavage and religation in the absence of base pairing. Abasic lesions as a tool to dissect enzyme mechanism
    • (1998) J. Biol. Chem. , vol.273 , pp. 17999-18002
    • Kingma, S.1    Osheroff, N.2
  • 125
    • 0032484105 scopus 로고    scopus 로고
    • Topoisomerase II site-directed alkylation of DNA by psorospermin and its effect on topoisomerase II-mediated DNA cleavage
    • (1998) J. Biol. Chem. , vol.273 , pp. 33020-33026
    • Kwok, Y.1    Hurley, L.H.2
  • 126
    • 0034193242 scopus 로고    scopus 로고
    • Sensitivity of human type II topoisomerases to DNA damage: Stimulation of enzyme-mediated DNA cleavage by abasic, oxidized and alkylated lesions
    • (2000) Nucleic Acids Res. , vol.28 , pp. 1947-1954
    • Sabourin, M.1    Osheroff, N.2
  • 127
    • 0033569745 scopus 로고    scopus 로고
    • Cytosine arabinoside lesions are position-specific topoisomerase II poisons and stimulate DNA cleavage mediated by the human type II enzymes
    • (1999) J. Biol. Chem. , vol.274 , pp. 29740-29743
    • Cline, S.D.1    Osheroff, N.2
  • 130
    • 0033529492 scopus 로고    scopus 로고
    • Interactions between DNA helicases and frozen topoisomerase IV-quinolone-DNA ternary complexes
    • (1999) J. Biol. Chem. , vol.274 , pp. 22747-22754
    • Shea, M.E.1    Hiasa, H.2
  • 132
    • 0028178785 scopus 로고
    • Meiosis-specific formation of joint DNA molecules containing sequences from homologous chromosomes
    • (1994) Cell , vol.76 , pp. 65-75
    • Collins, I.1    Newlon, C.S.2
  • 133
  • 149
    • 0027948119 scopus 로고
    • p53 status, DNA double-strand break repair proficiency, and radiation response of mouse lymphoid and myeloid cell lines
    • (1994) Int. J. Radiat. Biol. , vol.66 , pp. 557-560
    • Radford, I.R.1
  • 159
    • 0033609365 scopus 로고    scopus 로고
    • An acidic environment leads to p53 dependent induction of apoptosis in human adenoma and carcinoma cell lines: Implications for clonal selection during colorectal carcinogenesis
    • (1999) Oncogene , vol.18 , pp. 3199-3204
    • Williams, A.C.1    Collard, T.J.2    Paraskeva, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.