Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme

Biochimica et Biophysica Acta - Gene Structure and Expression

Volumn 1400, Issue 1-3, 1998, Pages 83-106

  Pommier, Yves ^a   Pourquier, Philippe ^a   Fan, Yi ^a   Strumberg, Dirk ^a  

^a Laboratory of Molecular Pharmacology   (United States)

Author keywords

Camptothecin; DNA break; DNA repair; DNA replication; Gene regulation; Recombination

Indexed keywords

CAMPTOTHECIN; DNA TOPOISOMERASE;

CATALYSIS; DNA CLEAVAGE; DNA REPAIR; DNA REPLICATION; DNA STRAND BREAKAGE; ENZYME MECHANISM; ENZYME REGULATION; EUKARYOTE; GENE TARGETING; GENETIC RECOMBINATION; GENETIC REGULATION; NONHUMAN; PRIORITY JOURNAL; REVIEW; TARGET CELL;

ANTINEOPLASTIC AGENTS; CAMPTOTHECIN; DNA; DNA TOPOISOMERASES, TYPE I; DRUG RESISTANCE; ENZYME INHIBITORS; INTERCALATING AGENTS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; POLYCYCLIC COMPOUNDS;

EID: 0032189683     PISSN: 01674781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4781(98)00129-8     Document Type: Review

References (289)

1. Wang J.C. Annu. Rev. Biochem. 65:1996;635-692.
2. Gupta M., Fujimori A., Pommier Y. Biochim. Biophys. Acta. 1262:1995;1-14.
3. Wang J.C. Annu. Rev. Biochem. 54:1985;665-697.
4. Wang J.C. Biochim. Biophys. Acta. 909:1987;1-9.
5. Gellert M. Annu. Rev. Biochem. 50:1981;879-910.
6. Liu L.F. Annu. Rev. Biochem. 58:1989;351-375.
7. Y. Pommier, A. Tanizawa, in: J. Hickman, T. Tritton (Eds.), Mammalian DNA Topoisomerase I and Its Inhibitors, Blackwell Scientific, Oxford, 1993, pp. 214-250.
8. Wallis J.W., Chrebet G., Brodsky G., Rolfe M., Rothstein R. Cell. 58:1989;409-419.
9. Hanai R., Caron P.R., Wang J.C. Proc. Natl. Acad. Sci. USA. 93:1996;3653-3657.
10. Kim R.A., Wang J.C. J. Biol. Chem. 267:1992;17178-17185.
11. Fritz E., Elsea S.H., Patel P.I., Meyn M.S. Proc. Natl. Acad. Sci. USA. 94:1997;4538-4542.
12. Gangloff S., MacDonald J.P., Bendixen C., Arthur L., Rothstein R. Mol. Cell. Biol. 14:1994;8391-8398.
13. Li W., Wang J.C. Proc. Natl. Acad. Sci. USA. 95:1998;1010-1013.
14. Wallis J.W., Chrebet G., Brodsky G., Rolfe M., Rothstein R. Cell. 58:1989;409-419.
15. Pulleyblank D.E., Morgan A.R. Biochemistry. 14:1975;5206-5209.
16. Hsieh T., Brutlag D. Cell. 21:1980;115-125.
17. Liu L.F. Methods Enzymol. 100:1983;133-137.
18. Koiwai O., Yasui Y., Sakai Y., Watanabe T., Ishii K., Yanagihara S., Andoh T. Gene. 125:1993;211-216.
19. Tanizawa A., Tabuchi A., Bertrand R., Pommier Y. J. Biol. Chem. 268:1993;25463-25468.
20. Brun G., Vannier P., Scovassi I., Callen J.-C. Eur. J. Biochem. 118:1981;407-415.
21. Castora F.J., Kelly W.G. Proc. Natl. Acad. Sci. USA. 83:1986;1680-1684.
22. Lazarus G.M., Henrich J.P., Kelly W.G., Schmitz S.A., Castora F.J. Biochemistry. 26:1987;6195-6203.
23. Lee M.P., Brown S.D., Chen A., Hsieh T.-S. Proc. Natl. Acad. Sci. USA. 90:1993;6656-6660.
24. Morham S., Kluckman K.D., Voulomanos N., Smithies O. Mol. Cell. Biol. 16:1996;6804-6809.
25. Fernandez-Beros M.-E., Tse-Dinh Y.-C. J. Bacteriol. 174:1992;7059-7062.
26. Bjornsti M.-A., Benedetti P., Viglianti G.A., Wang J.C. Cancer Res. 49:1989;6318-6323.
27. Madden K.R., Champoux J.J. Cancer Res. 52:1992;525-532.
28. Heck M.M., Hittelman W.N., Earnshaw W.C. Proc. Natl. Acad. Sci. USA. 85:1988;1086-1090.
29. Romig H., Richter A. Biochim. Biophys. Acta. 1048:1990;274-280.
30. Thrash C., Voelkel K., DiNardo S., Sternglanz R. J. Biol. Chem. 259:1984;1375-1377.
31. Uemura T., Yanagida M. EMBO J. 3:1984;1337-1351.
32. Christman M.F., Dietrich F.S., Fink G.R. Cell. 55:1988;413-425.
33. Kim R.A., Wang J.C. Cell. 57:1989;975-985.
34. Nitiss J.L., Rose A., Sykes K.C., Harris J., Zhou J. Ann. New York Acad. Sci. 803:1996;32-43.
35. Knab A.M., Fertala J., Bjornsti M.-A. J. Biol. Chem. 268:1993;22322-22330.
36. Goldman G.H., Yu C., Wu H.-Y., Sanders M.M., La Voie E.J., Liu L.F. Biochemistry. 36:1997;6488-6494.
37. Fostel J.M., Montgomery D. Antimicrob. Agents Chemother. 39:1995;586-592.
38. Bauer W.R., Ressner E.C., Kates J., Patzke J.V. Proc. Natl. Acad. Sci. USA. 74:1977;1841-1845.
39. Shaffter R., Traktman P. J. Biol. Chem. 262:1987;9309-9315.
40. Shuman S., Moss B. Proc. Natl. Acad. Sci. USA. 84:1987;7478-7482.
41. Upton C., Opgenorth A., Traktman P., McFadden G. Virology. 176:1990;439-447.
42. Zantinge J.L., Krell P.J., Derbyshire J.B., Nagy E. J. Gen. Virol. 77:1996;603-614.
43. Schaak J., Schedl P., Shenk T. J. Virol. 64:1990;78-85.
44. Hwang Y., Wang B., Bushman F.D. J. Virol. 72:1998;3201-3406.
45. Shchelkunov S.N., Blinov V.M., Sandakhchiev L.S. FEBS Lett. 319:1993;80-83.
46. P. Traktman, in: M.L. DePamphilis, (Ed.), Poxvirus DNA Replication, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1996, pp. 775-798.
47. Shuman S. J. Biol. Chem. 266:1991;1796-1803.
48. Palaniyar N., Fisher C., Parks R., Evans D.H. Virology. 221:1996;351-354.
49. Priel E., Showalter S.D., Roberts M., Oroszlan S., Segal S., Aboud M., Blair D.G. EMBO J. 9:1990;4167-4172.
50. Li C.J., Zhang L.J., Dezube B.J., Crumpacker C.S., Pardee A.B. Proc. Natl. Acad. Sci. USA. 90:1993;1839-1842.
51. Zhang J.L., Sharma P.L., Li C.J., Dezube B.J., Pardee A.B., Crumpacker C.S. Antimicrob. Agents Chemother. 41:1997;977-981.
52. Takahashi H., Matsuda M., Kojima A., Sata T., Andoh T., Kurata T., Nagashima K., Hall W.W. Proc. Natl. Acad. Sci. USA. 92:1995;5694-5698.
53. Jardine D., TAchedjian G., Locarnini S., Birch C. AIDS Res. Hum. Retroviruses. 9:1994;1245-1250.
54. Y. Pommier, M.R. Fesen, F. Goldwasser, in: B.A. Chabner, D.L. Longo (Eds.), Topoisomerase II Inhibitors: The Epipodophyllotoxins, m-AMSA, and the Ellipticine Derivatives, 2nd ed., Lippincott-Raven, Philadelphia, PA, 1996, pp. 435-461.
55. Kawanishi M. J. Gen. Virol. 74:1993;2263-2268.
56. Yamada Y., Yamamoto N., Maeno K., Nishiyama Y. Arch. Virol. 110:1990;121-127.
57. Liu L.F., Depew R.E., Wang J.C. J. Mol. Biol. 106:1976;439-452.
58. Depew R.E., Liu L.F., Wang J.C. J. Biol. Chem. 253:1978;511-518.
59. Been M.D., Champoux J.J. J. Mol. Biol. 180:1984;515-531.
60. Christiansen K., Svejstrup B.D., Andersen A.H., Westergaard O. J. Biol. Chem. 268:1993;9690-9701.
61. Shuman S. J. Biol. Chem. 266:1991;11372-11379.
62. Jaxel C., Capranico G., Kerrigan D., Kohn K.W., Pommier Y. J. Biol. Chem. 266:1991;20418-20423.
63. Camilloni G., Di Mauro E., Caserta M., Di Mauro E. Nucleic Acids Res. 16:1989;7071-7085.
64. Caserta M., Amadei A., Di Mauro E., Camilloni G. Nucleic Acids Res. 17:1989;8463-8474.
65. Caserta M., Amadei A., Camilloni G., Di Mauro E. Biochemistry. 29:1990;8152-8157.
66. Krogh S., Mortensen U.H., Westergaard O., Bonven B.J. Nucleic Acids Res. 19:1991;1235-1241.
67. Leteurtre F., Kohlhagen G., Fesen M.R., Tanizawa A., Kohn K.W., Pommier Y. J. Biol. Chem. 269:1994;7893-7900.
68. Wang L.-F., Ting C.-Y., Lo C.-K., Su J.-S., Mickley L.A., Fojo A.T., Whang-Peng J., Hwang J. Cancer Res. 57:1997;1516-1522.
69. Jensen A.D., Svejstrup J.Q. Eur. J. Biochem. 236:1996;389-394.
70. Champoux J.J. J. Biol. Chem. 256:1981;4805-4809.
71. Lynn R.M., Bjornsti M.A., Caron P.R., Wang J.C. Proc. Natl. Acad. Sci. USA. 86:1989;3559-3563.
72. Shuman S., Kane E.M., Morham S.G. Proc. Natl. Acad. Sci. USA. 86:1989;9793-9797.
73. Fujimori A., Harker W.G., Kohlhagen G., Hoki Y., Pommier Y. Cancer Res. 55:1995;1339-1346.
74. Jaxel C., Kohn K.W., Pommier Y. Nucleic Acids Res. 16:1988;11157-11170.
75. Tanizawa A., Kohn K.W., Pommier Y. Nucleic Acids Res. 21:1993;5157-5166.
76. Pourquier P., Ueng L.-M., Kohlhagen G., Mazumder A., Gupta M., Kohn K.W., Pommier Y. J. Biol. Chem. 272:1997;7792-7796.
77. Pourquier P., Pilon A., Kohlhagen G., Mazumder A., Sharma A., Pommier Y. J. Biol. Chem. 272:1997;26441-26447.
78. Yeh Y.-C., Liu H.-F., Ellis C.A., Lu A.-L. J. Biol. Chem. 269:1994;15498-15504.
79. Stewart L., Redinbo M.R., Qiu X., Hol W.G.J., Champoux J.J. Science. 279:1998;1534-1541.
80. Cheng C., Kussie P., Pavletich N., Shuman S. Cell. 92:1998;841-850.
81. Redinbo M.R., Stewart L., Kuhn P., Champoux J.J., Hol W.G.J. Science. 279:1998;1504-1513.
82. Stivers J.T., Harris T.K., Mildvan A.S. Biochemistry. 36:1997;5212-5222.
83. Lindsley J.E., Wang J.C. J. Biol. Chem. 268:1993;8096-8104.
84. Berger J.M., Gamblin S.J., Harrison S.C., Wang J.C. Nature. 379:1996;225-232.
85. Christiansen K., Knudsen B., Westergaard O. J. Biol. Chem. 15:1994;11367-11373.
86. Yang S.-W., Burgin A.B., Huizenga B.N., Robertson C.A., Yao K.C., Nash H.A. Proc. Natl. Acad. Sci. USA. 93:1996;11534-11539.
87. J. Pouliot, H.A. Nash, P. Pourquier, Y. Pommier, (unpublished).
88. Sekiguchi J., Shuman S. Mol. Cell. 1:1997;89-97.
89. Shuman S. J. Biol. Chem. 269:1994;32678-32684.
90. Pommier Y., Leteurtre F., Fesen M., Fujimori A., Bertrand R., Solary E., Kohlhagen G., Kohn K.W. Cancer Invest. 12:1994;530-542.
91. Chen A.Y., Liu L.F. Annu. Rev. Pharmacol. Toxicol. 94:1994;194-218.
92. Svejstrup J.Q., Christiansen K., Gromova I.I., Andersen A.H., Westergaard O. J. Mol. Biol. 222:1991;669-678.
93. Shuman S. J. Biol. Chem. 267:1992;16755-16758.
94. Shuman S. J. Biol. Chem. 267:1992;8620-8627.
95. Christiansen K., Westergaard O. J. Biol. Chem. 269:1994;721-729.
96. Christiansen K., Westergaard O. J. Biol. Chem. 269:1994;721-729.
97. J. Champoux, in: J.C. Wang, N.R. Cozarelli (Eds.), Mechanistic Aspects of Type-I Topoisomerases, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1990, pp. 217-242.
98. Capranico G., Jaxel C., Roberge M., Kohn K.W., Pommier Y. Nucleic Acids Res. 18:1990;4553-4559.
99. Kreuzer K.N., Alberts B.M. J. Biol. Chem. 259:1984;5339-5346.
100. Leteurtre F., Kohlhagen G., Fesen M R., Tanizawa A., Kohn K.W., Pommier Y. J. Biol. Chem. 269:1994;7893-7900.
101. Perini R., Caserta M., Mauro D.E. J. Mol. Biol. 231:1993;634-645.
102. Javaherian K., Liu L.F. Nucleic Acids Res. 11:1983;461-472.
103. Srivenugopal K.S., Morris D.R. Biochemistry. 24:1985;4766-4771.
104. Ishimi Y., Nishizawa M., Andoh T. Eur. J. Biochem. 202:1991;835-839.
105. Yang L., Wold M.S., Li J.J., Kelly T.J., Liu L.F. Proc. Natl. Acad. Sci. USA. 84:1987;950-954.
106. Avemann K., Knippers R., Koller T., Sogo J.M. Mol. Cell. Biol. 8:1988;3026-3034.
107. Shin C.-G., Snapka R.M. Biochem. Biophys. Res. Commun. 168:1990;135-140.
108. Hsiang Y.-H., Lihou M.G., Liu L.F. Cancer Res. 49:1989;5077-5082.
109. Holm C., Covey J.M., Kerrigan D., Pommier Y. Cancer Res. 49:1989;6365-6368.
110. Kroeger P.E., Rowe T.C. Biochemistry. 31:1992;2492-2501.
111. Zhang H., Wang J.C., Liu L.F. Proc. Natl. Acad. Sci. USA. 85:1988;1060-1064.
112. Gilmour D.S., Pflugfelder G., Wang J.C., Lis J.T. Cell. 44:1986;401-407.
113. Stewart A.F., Herrera R.E., Nordheim A. Cell. 60:1990;141-146.
114. Liu L.F., Wang J.C. Proc. Natl. Acad. Sci. USA. 84:1987;7024-7027.
115. Wang J., Lynch S. Curr. Opin. Gene Dev. 3:1993;764-768.
116. Merino A., Madden K.R., Lane W.S., Champoux J.J., Reinberg D. Nature. 365:1993;227-232.
117. Kretzschmar M., Meisterernst M., Roeder R. Proc. Natl. Acad. Sci. USA. 90:1993;11508-11512.
118. Horwitz S.B., Chang C.K., Grollman A.P. Mol. Pharmacol. 7:1971;632-644.
119. Bendixen C., Thomsen B., Alsner J., Westergaard O. Biochemistry. 29:1990;5613-5619.
120. Pommier Y., Jenkins J., Kohlhagen G., Leteurtre F. Mutat. Res. 337:1995;135-145.
121. Bullock P., Champoux J.J., Botchan M. Science. 230:1985;954-958.
122. Hino O., Ohtake K., Rogler C.E. J. Virol. 63:1989;2638-2643.
123. Wang H.-P., Rogler C.E. J. Virol. 65:1991;2381-2392.
124. Shuman S. Proc. Natl. Acad. Sci. USA. 86:1989;3489-3493.
125. Sekiguchi J., Seeman N.C., Shuman S. Proc. Natl. Acad. Sci. USA. 93:1996;785-789.
126. Yeh Y.C., Liu H.F., Ellis C.A., Lu A.L. J. Biol. Chem. 269:1994;15498-15504.
127. Stewart A.F., Schütz G. Cell. 50:1987;1109-1117.
128. Gilmour D.S., Elgin S.C. Mol. Cell. Biol. 7:1987;141-148.
129. Ljungman M., Hanawalt P.C. Carcinogenesis. 17:1996;31-35.
130. Egyhazi E., Durban E. Mol. Cell. Biol. 7:1987;4308-4316.
131. Kretzschmar M., Meisterernst M., Roeder R.G. Proc. Natl. Acad. Sci. USA. 90:1993;11508-11512.
132. Merino A., Madden K.R., Lane W.S., Champoux J.J., Reinberg D. Nature. 365:1993;227-232.
133. Shykind B.M., Kim J., Stewart L., Champoux J.J., Sharp P.A. Genes Dev. 11:1997;397-407.
134. Castano I.B., Heath-Pagliuso S., Sadoff B.U., Fitzhugh D.J., Christman M.F. Nucleic Acids Res. 24:1996;2404-2410.
135. Sadoff B.U., Heath-Pagliuso S., Casta-o I.B., Zhu Y., Kieff F.S., Christman M.F. Genetics. 141:1995;465-479.
136. Castano I.B., Brzoska P.M., Sadoff B.U., Chen H., Christman M.F. Genes Dev. 10:1996;2564-2576.
137. Subramanian D., Rosenstein B.S., Muller M.T. Cancer Res. 58:1998;976-984.
138. Lanza A., Tornatelli S., Rodolfo C., Scanavini M.C., Pedrini A.M. J. Biol. Chem. 271:1996;6978-6986.
139. Rossi F., Labourier E., Forne T., Divita G., Derancourt J., Riou J.F., Antoine E., Cathala G., Brunel C., Tazi J. Nature. 381:1996;80-82.
140. Heiland S., Knippers R., Kunze N. Eur. J. Biochem. 217:1993;813-822.
141. Kunze N., Klein M., Richter A., Knippers R. Eur. J. Biochem. 194:1990;323-330.
142. Kunze N., Yang G., Dölberg M., Sundarp R., Knippers R., Richter A. J. Biol. Chem. 266:1991;9610-9616.
143. Duguet M., Lavenot C., Harper F., Mirambeau G., De Recondo A.M. Nucleic Acids Res. 11:1983;1059-1075.
144. Hwong C.-L., Chen M.-S., Hwang J. J. Biol. Chem. 264:1989;14923-14926.
145. Romig H., Richter A. Nucleic Acids Res. 18:1990;801-808.
146. Sobczak J., Tournier M.F., Lotti A.M., Duguet M. Eur. J. Biochem. 180:1989;49-53.
147. Tse-Dinh Y.C., Wong T.W., Goldberg A.R. Nature. 312:1984;785-786.
148. Samuels D.S., Shimizu Y., Shimizu N. FEBS Lett. 259:1989;57-60.
149. Pommier Y., Kerrigan D., Hartmann K.D., Glazer R.I. J. Biol. Chem. 16:1990;9418-9422.
150. Durban E., Mills J.S., Roll D., Busch H. Biochem. Biophys. Res. Commun. 111:1983;897-905.
151. Durban E., Goodenough M., Mills J., Busch H. EMBO J. 4:1985;2921-2926.
152. Samuel D.S., Shimizu N. J. Biol. Chem. 267:1992;11156-11162.
153. Cardellini E., Durban E. Biochem. J. 291:1993;303-307.
154. D.S. Samuels, Y. Shimizu, T. Nakabayashi, N. Shimizu, Biochem. Biophy. Acta (1994).
155. Turman M.A., Douvas A. Biochem. Med. Metab. Biol. 50:1993;210-225.
156. Kasid U.N., Halligan B., Liu L.F., Dritschilo A., Smulson M. J. Biol. Chem. 264:1989;18687-18692.
157. Ferro A.M., McElwain M.C., Olivera B.M. Cold. Spring. Harb. Symp. Quant. Biol. 49:1984;683-690.
158. Park J.K., Kim W.J., Park Y.S., Choi H.S., Yu J.E., Han D.M., Park S.D. Cell Mol. Biol. 37:1991;739-744.
159. Mattern M.R., Mong S.M., Bartus H.F., Mirabelli C.K., Crooke S.T., Johnson R.K. Cancer Res. 47:1987;1793-1798.
160. Chatterjee S., Hirschler N.V., Petzold S.J., Berger S.J., Berger N.A. Exp. Cell. Res. 184:1989;1-15.
161. Durkacz B.W., Omidiji O., Gray D.A., Shall S. Nature. 283:1980;593-596.
162. Boulikas T. Anticancer Res. 11:1991;489-528.
163. Murcia G., Murcia J.M. Trends Biochem. Sci. 19:1994;172-176.
164. Malanga M., Aithaus F.R. J. Biol. Chem. 269:1994;17691-17696.
165. Boothman D.A., Fukunaga N., Wang M. Cancer Res. 54:1994;4618-4626.
166. Rose K.M., Szopa J., Han F.S., Cheng Y.C., Richter A., Scheer U. Chromosoma. 96:1988;411-416.
167. Gobert C., Bracco L., Rossi F., Olivier M., Tazi J., Lavelle F., Larsen A.K., Riou J.F. Biochemistry. 35:1996;5778-5786.
168. Ciavarra R.P., Goldman C., Wen K.K., Tedeschi B., Castora F. Proc. Natl. Acad. Sci. USA. 91:1994;1751-1755.
169. Simmons D.T., Melendy T., Usher D., Stillman B. Virology. 222:1996;365-374.
170. Haluska P., Saleem A., Edwards T.K., Rubin E. Nucleic Acids Res. 26:1998;1841-1847.
171. Y. Pommier, G. Kohlhagen, C. Wu, D.T. Simmons, Biochemistry, in press.
172. Y. Pommier, in: B.A. Teicher (Ed.), DNA Topoisomerase Ii Inhibitors, Humana Press, Totowa, NJ, 1997, pp. 153-174.
173. Nitiss J., Wang J.C. Proc. Natl. Acad. Sci. USA. 85:1988;7501-7505.
174. Y. Pommier, M. Gupta, M. Valenti, W. Nieves-Neira, in: P. Pantazis, B.C. Giovanella, M.L. Rothenberg (Eds.), Cellular resistance to camptothecins, The New York Academy of Sciences, New York, 1996, pp. 60-73.
175. Pommier Y. Semin. Oncol. 23:1996;1-10.
176. Wall M.E., Wani M.C., Cooke C.E., Palmer K.H., McPhail A.T., Slim G.A. J. Am. Chem. Soc. 88:1966;3888-3890.
177. Giovanella B.C., Stehlin J.S., Wall M.E., Wani M.C., Nicholas A.W., Liu L.F., Silber R., Potmesil M. Science. 246:1989;1046-1048.
178. Slichenmyer W.J., Rowinsky E.K., Donehower R.C., Kaufmann S.H. J. Natl. Cancer Inst. 85:1993;271-287.
179. Armand J.P., Ducreux M., Mahjoubi M., Abigerges D., Bugat R., Chabot G., Herait P., de Forni M., Rougier P. Eur. J. Cancer. 31A:1995;1283-1287.
180. O'Reilly S., Rowinsky E.K. Crit. Rev. Oncol./Hematol. 24:1996;47-70.
181. Dancey J., Eisenhauer E.A. Br. J. Cancer. 74:1996;327-338.
182. Tanizawa A., Fujimori A., Fujimori Y., Pommier Y. J. Natl. Cancer Inst. 86:1994;836-842.
183. Tanizawa A., Kohn K.W., Kohlhagen G., Leteurtre F., Pommier Y. Biochemistry. 43:1995;7200-7206.
184. Covey J.M., Jaxel C., Kohn K.W., Pommier Y. Cancer Res. 49:1989;5016-5022.
185. Hsiang Y.H., Hertzberg R., Hecht S., Liu L.F. J. Biol. Chem. 260:1985;14873-14878.
186. Porter S.E., Champoux J.J. Mol. Cell. Biol. 9:1989;541-550.
187. Bonven B.J., Gocke E., Westergaard O. Cell. 41:1985;541-551.
188. Kroeger P.E., Rowe T.C. Nucleic Acids Res. 17:1989;8495-8509.
189. Stewart A.F., Schutz G. Cell. 50:1987;1109-1117.
190. Bronstein I.B., Gromova I.I., Razin S.V. Mol. Cell. Biochem. 101:1991;115-124.
191. Perez-Stable C., Shen C.C., Shen C.-K.J. Nucleic Acids Res. 16:1988;7975-7993.
192. Thomsen B., Mollerup S., Bonven B.J., Frank R., Blocker H., Nielsen O.F., Westergaard O. EMBO J. 6:1987;1817-1823.
193. Porter S.E., Champoux J.J. Nucleic Acids Res. 17:1989;8521-8532.
194. Tanizawa A., Kohn K., Pommier Y. Nucleic Acids Res. 21:1993;5157-5166.
195. Pommier Y., Kohlhagen G., Kohn F., Leteurtre F., Wani M.C., Wall M.E. Proc. Natl. Acad. Sci. USA. 92:1995;8861-8865.
196. Y. Pommier, A. Fujimori, Y. Hoki, M. Gupta, M. Gariboldi, in: S. Gupta, T. Tsuruo (Eds.), DNA Topoisomerase I Inhibitors and Multidrug Resistance, John Wiley, Oxford, 1996, pp. 119-135.
197. Fujimori A., Harker W.G., Kohlhagen G., Hoki Y., Pommier Y. Cancer Res. 55:1995;1339-1346.
198. Ohashi N., Fujiwara Y., Yamaoka N., Katoh O., Satow Y., Yamakido M. Jpn. J. Cancer Res. 87:1996;1280-1287.
199. Takatani H., Oka M., Fukuda M., Narasaki F., Nakano R., Ikeda K., Terashi K., Kinshita A., Soda H., Kanda T., Schneider E., Kohno S. Jpn. J. Cancer Res. 88:1997;160-165.
200. Yang C.-H.J., Horton J.K., Cowan K.H., Schneider E. Cancer Res. 55:1995;4004-4009.
201. Beidler D.R., Chang J.-Y., Zhou B.-S., Cheng Y.-C. Cancer Res. 56:1995;345.
202. Fujimori A., Gupta M., Hoki Y., Pommier Y. Mol. Pharmacol. 50:1996;1472-1478.
203. Kauh E.A., Bjornsti M.-A. Proc. Natl. Acad. Sci. USA. 92:1995;6299-6303.
204. Fujimori A., Hoki Y., Popescu N., Pommier Y. Oncol. Res. 8:1996;295-301.
205. Harker W.G., Slade K.L., Parr R.L., Feldhoff P.W., Sullivan D.M., Holguin M.H. Cancer Res. 55:1995;1707-1716.
206. Leteurtre F., Fesen M., Kohlhagen G., Kohn K.W., Pommier Y. Biochemistry. 32:1993;8955-8962.
207. Yang D., Strode J.T., Spielmann H.P., Wang A.H.J., Burke T.G. J. Am. Chem. Soc. 120:1998;2979-2980.
208. Jaxel C., Kohn K.W., Wani M.C., Wall M.E., Pommier Y. Cancer Res. 49:1989;1465-1469.
209. Y. Pommier, C. Jaxel, C. Heise, D. Kerrigan, K.W. Kohn, in: M. Potmesil, K.W. Kohn (Eds.), Structure-Activity Relationship of Topoisomerase I Inhibition by Camptothecin Derivatives: Evidence for the Existence of a Ternary Complex, Oxford University Press, New York, 1991, pp. 121-132.
210. Wall M.E., Wani M.C. Cancer Res. 55:1995;753-760.
211. Valenti M., Nieves-Neira W., Kohlhagen G., Kohn K.W., Wall M.E., Wani M.C., Pommier Y. Mol. Pharmacol. 52:1997;82-87.
212. Hsiang Y.-H., Liu L.F., Wall M.E., Wani M.C., Nicholas A.W., Manikumar G., Kirschenbaum S., Silber R., Potmesil M. Cancer Res. 49:1989;4385-4389.
213. Luzzio M.J., Besterman J.M., Emerson D.L., Evans M.G., Lackey K., Leitner P.L., McIntyre G., Morton B., Myers P.L., Peel M., Sisco J.M., Sternbach D.D., Tong W.-Q., Truesdale A., Uehling D.E., Vuong A., Yates J. J. Med. Chem. 38:1995;395-401.
214. Taagepera S., Rao P.N., Drake F.H., Gorbsky G.J. Proc. Natl. Acad. Sci. USA. 90:1993;8407-8411.
215. Hertzberg R.P., Caranfa M.J., Hecht S.M. Biochemistry. 28:1989;4629-4638.
216. Y. Fan, K.W. Kohn, L.M. Shi, J.N. Weinstein, Y. Pommier, J. Med. Chem., in press.
217. Pommier Y., Tanizawa A., Kohn K.W. Adv. Pharmacol. 29B:1994;73-91.
218. Crow R.T., Crothers D.M. J. Med. Chem. 37:1994;3191-3194.
219. Yamashita Y., Kawada S.-Z., Fujii N., Nakano H. Biochemistry. 30:1991;5838-5845.
220. Fujii N., Yamashita Y., Chiba S., Uosaki Y., Saitoh Y., Tuji Y., Nakano H. J. Antibiot. 46:1993;1173-1174.
221. Fujii N., Yamashita Y., Ando K., Agatsuma T., Saitoh Y., Gomi K., Nishiie Y., Nakano H. J. Antibiot. 47:1994;949-951.
222. Fujii N., Yamashita Y., Mizukami T., Nakano H. Mol. Pharmacol. 51:1997;269-276.
223. Leteurtre F., Fujimori A., Tanizawa A., Chhabra A., Mazumder A., Kohlhagen G., Nakano H., Pommier Y. J. Biol. Chem. 269:1994;28702-28707.
224. Fang S.-D., Wang L.-K., Hecht S.M. J. Org. Chem. 58:1993;5025-5027.
225. Wang L.-K., Johnson R.K., Hecht S.M. Chem. Res. Toxicol. 6:1993;813-818.
226. Larsen A.K., Grondard L., Couprie J., Desoizé B., Comof L., Jardillier J.-C., Riou J.-F. Biochem. Pharmacol. 19:1993;1403-1412.
227. Janin Y.L., Croisy A., Riou J.-F., Bisagni E. J. Med. Chem. 36:1993;3686-3692.
228. M. Suffness, G.A. Cordell, in: A. Brossi (Ed.), Antitumor alkaloids, Vol. XXV, Academic Press, Orlando, 1985, pp. 178-188.
229. Zee-Cheng K., Paull K., Cheng C. J. Med. Chem. 17:1974;347-351.
230. Gatto B., Sanders M.M., Yu C., Wu H.Y., Makhey D., LaVoie E.J., Liu L.F. Cancer Res. 56:1996;2795-2800.
231. Wang L.K., Rogers B.D., Hecht S.M. Chem. Res. Toxicol. 9:1996;75-83.
232. Kobayashi Y., Yamashita Y., Fujii N., Takaboshi K., Kawakami T., Kawamura M., Mizukami T., Nakano H. Planta Med. 61:1995;414-418.
233. Poddevin B., Riou J.-F., Lavelle F., Pommier Y. Mol. Pharmacol. 44:1993;767-774.
234. Nabiev I., Chourpa I., Riou J.-F., Nguyen C.H., Lavelle F., Manfait M. Biochemistry. 33:1994;9013-9023.
235. Abigerges D., Armand J.P., Chabot G.G., Bruno R., Bissery M.C., Bayssas M., Klink-Alakl M., Clavel M., Catimel G. Anticancer Drugs. 7:1996;166-174.
236. Riou J.-F., Helissey P., Grondard L., Giorgi-Renault S. Mol. Pharmacol. 40:1991;699-706.
237. Callais F., Helissey P., Min S., Festy B., Giorgi-Renault S. Mutat. Res. 311:1994;149-156.
238. Kokoshka J.M., Capson T.L., Holden J.A., Ireland C.M., Barrows L.R. Anticancer Drugs. 7:1996;758-765.
239. Paull K.D., Shoemaker R.H., Hodes L., Monks A., Scudiero D.A., Rubinstein L., Plowman J., Boyd M. J. Natl. Cancer Inst. 81:1989;1088-1092.
240. Boyd M.R., Paull K.D. Drug Dev. Res. 34:1995;91-109.
241. G. Kohlhagen, K. Paull, M. Cushman, P. Nagafufuji, Y. Pommier, Mol. Pharmacol., in press.
242. Kawada S.-Z., Yamashita Y., Uosaki Y., Gomi K., Iwasaki T., Takiguchi T., Nakano H. J. Antibiot. 45:1992;1182-1184.
243. Yamashita Y., Fujii N., Murakata C., Ashizawa T., Okabe M., Nakano H. Biochemistry. 31:1992;12069-12075.
244. Yoshinari T., Yamada A., Uemura D., Nomura K., Arakawa H., Kojiri K., Yoshida E., Suda H., Okura A. Cancer Res. 53:1993;490-494.
245. Yoshinari T., Matsumoto M., Arakawa H., Okada H., Noguchi K., Suda H., Okura A., Nishimura S. Cancer Res. 55:1995;1310-1315.
246. Kanzawa F., Nishio K., Kubuta N., Saijo N. Cancer Res. 55:1995;2806-2813.
247. Arakawa H., Iguchi T., Morita M., Yoshinari T., Kojiri K., Suda H., Okura A., Nishimura S. Cancer Res. 55:1995;1316-1320.
248. Arakawa H., Matsumoto H., Morita M., Sasaki M., Taguchi K., Okura A., Nishimura S. Jpn. J. Cancer Res. 87:1996;518-523.
249. Fukasawa K., Komatani H., Hara Y., Suda H., Okura A., Nishimura S., Yoshinari T. Int. J. Cancer. 75:1998;145-150.
250. Bertrand R., Solary E., Kohn K.W., O'Connor P., Pommier Y. Exp. Cell Res. 211:1994;314-321.
251. Shao R.-G., Shimizu T., Pommier Y. Exp. Cell Res. 234:1997;388-397.
252. Bailly C., Riou J.-F., Colson P., Houssier C., Rodriguez-Pereira E., Prudhomme M. Biochemistry. 36:1997;3917-3929.
253. Rodrigues-Pereira E., Belin L., Sancelme M., Prudhomme M., Ollier M., Rapp M., Servere D., Riou J.-F., Fabbro D. J. Med. Chem. 39:1996;4471-4477.
254. Kim J.S., Gatto B., Yu C., Liu A., Liu L.F., LaVoie E.J. J. Med. Chem. 39:1996;992-998.
255. Sun Q., Gatto B., Yu C., Liu A., Liu L.F., LaVoie E.J. J. Med. Chem. 38:1995;3638-3644.
256. Chen A.Y., Yu C., Gatto B., Liu L.F. Proc. Natl. Acad. Sci. USA. 90:1993;8131-8135.
257. Kim J.S., Sun Q., Gatto B., Yu C., Liu A., Liu L.F., LaVoie E.J. Bioorg. Med. Chem. 4:1996;621-630.
258. Fujii N., Yamashita Y., Saitoh Y., Nakano H. J. Biol. Chem. 268:1993;13160-13165.
259. Wassermann K., Markovits J., Jaxel C., Capranico G., Kohn K.W., Pommier Y. Mol. Pharmacol. 38:1990;38-45.
260. Trask D.K., Muller M.T. Proc. Natl. Acad. Sci. USA. 85:1988;1417-1421.
261. Sørensen B.S., Jensen P., Sehested M., Jensen P.S., Kjeldsen E., Nielsen O.F., Alsner J. Biochem. Pharmacol. 47:1994;2105-2110.
262. Cummings J., Macpherson J.S., Meikle I., Smyth J.F. Biochem. Pharmacol. 52:1996;979-990.
263. Macpherson J.S., Cummings J., Meikle I., Miller E.P., Smyth J.F. Eur. J. Cancer. 33:1997;280-283.
264. Cummings J., Hadfield J.A., Meikle I., McGown A.T., Smyth J.F. Anticancer Drugs. 7:1996;636-641.
265. Sørensen B.S., Jensen P.B., Sehested M., Jensen P.S., Kjeldsen E., Nielsen O., Alsner J. Biochem. Pharmacol. 47:1996;2105-2110.
266. Horiguchi T., Hayashi K., Tsubotani S., Iinuma S., Harada S., Tanida S. J. Antibiot. 47:1994;545-556.
267. Mortensen U.H., Stevnsner T., Krogh S., Olesen K., Westergaard O., Bonven B.J. Nucleic Acids Res. 18:1990;1983-1989.
268. Beerman T.A., McHugh M.M., Sigmund R., Lown J.W., Rao K.E., Bathini Y. Biochim. Biophys. Acta. 1131:1992;53-61.
269. Xie G., Gupta R., Atchison K., Lown J.W. J. Med. Chem. 39:1996;1049-1055.
270. Tanabe K., Ikegami R., Andoh T. Cancer Res. 51:1991;4903-4908.
271. Boothman D.A., Trask D.K., Pardee A.B. Cancer Res. 49:1989;605-612.
272. Li C.J., Averboukh L., Pardee A.B. J. Biol. Chem. 268:1993;22463-22468.
273. Frydman B., Marton L.J., Sun J.S., Neder K., Witiak D.T., Liu A.A., Wang H.M., Mao Y., Wu H.Y., Sanders M.M., Liu L.F. Cancer Res. 57:1997;620-627.
274. Schuerch A.R., Wehrli W. Eur. J. Biochem. 84:1978;197-205.
275. Ahn B.Z., Baik K.U., Kweon G.R., Lim K., Hwang B.D. J. Med. Chem. 38:1995;1044-1047.
276. Hecht S.M., Berry D.E., MacKenzie L.J., Busby R.W., Nasuti C.A. J. Nat. Prod. 55:1992;401-413.
277. Berry D.E., MacKenzie L., Shultis E.A., Chan J.A. J. Org. Chem. 57:1992;420-422.
278. Funabashi Y., Horiguchi T., Iinuma S., Tanida S., Harada S. J. Antibiot. 47:1994;1202-1218.
279. Constantinou A., Stoner G.D., Mehta R., Rao K., Runyan C., Moon R. Nutr. Cancer. 23:1995;121-130.
280. Rubin E., Pantazis P., Toppmeyer D., Giovanella B., Kufe D. J. Biol. Chem. 269:1994;2433-2439.
281. Li X.-G., Haluska P., Hsiang Y.-H., Bharti A.K., Kufe D.W., Liu L.F., Rubin E.H. Biochem. Pharmacol. 53:1997;1019-1027.
282. Benedetti P., Fioranti P., Capuani L., Wang J.C. Cancer Res. 53:1993;4343-4348.
283. Tanizawa A., Bertrand R., Kohlhagen G., Tabuchi A., Jenkins J., Pommier Y. J. Biol. Chem. 268:1993;25463-25468.
284. Tanizawa A., Pommier Y. Cancer Res. 52:1992;1848-1854.
285. Kjeldsen E., Bonven B.J., Andoh T., Ishii K., Okada K., Bolund L., Westergaard O. J. Biol. Chem. 263:1988;3912-3916.
286. Tamura H.-O., Kohchi C., Yamada R., Ikeda T., Koiwa O., Patterson E., Keene J.D., Okada K., Kjeldsen E., Nishikawa K., Andoh T. Nucleic Acids Res. 19:1991;69-75.
287. Kubota N., Kanzawa F., Nishio K., Takeda Y., Ohmori T., Fujiwara Y., Terashima Y., Saijo N. Biochem. Biophys. Res. Commun. 188:1992;571-577.
288. Juan C.C., Hwang J.L., Liu A.A., Whang-Peng J., Knutsen T., Huebner K., Croce C.M., Zhang H., Wang J.C., Liu L.F. Proc. Natl. Acad. Sci. USA. 85:1988;8910-8913.
289. Desai D.S., Liu L.F., Vasquez-Abad D., D'Arpa P. J. Biol. Chem. 272:1997;24159-24164.