Topoisomerase II site-directed alkylation of DNA by psorospermin and its effect on topoisomerase II-mediated DNA cleavage

Journal of Biological Chemistry

Volumn 273, Issue 49, 1998, Pages 33020-33026

  Kwok, Yan ^a   Hurley, Laurence H ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); PSOROSPERMIN; SPERMINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER; DNA ALKYLATION; DNA DEGRADATION; DRUG DESIGN; DRUG DNA INTERACTION; DRUG SYNTHESIS; PRIORITY JOURNAL; TUMOR;

ADENOSINE TRIPHOSPHATE; ADENYLYL IMIDODIPHOSPHATE; ALKYLATION; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BASE SEQUENCE; DNA; DNA ADDUCTS; DNA TOPOISOMERASES, TYPE II; DROSOPHILA; GUANINE; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; MAGNESIUM; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; SUBSTRATE SPECIFICITY; XANTHENES; XANTHONES;

EID: 0032484105     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.49.33020     Document Type: Article

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