DNA minor groove binding-directed poisoning of human DNA topoisomerase I by terbenzimidazoles

Biochemistry

Volumn 37, Issue 10, 1998, Pages 3558-3566

  Xu, Zhitao ^b   Li, Tsai Kun ^b   Kim, Jung Sun ^b   LaVoie, Edmond J ^b   Breslauer, Kenneth J ^b   Liu, Leroy F ^b   Pilch, Daniel S ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BENZIMIDAZOLE DERIVATIVE; DNA; DNA TOPOISOMERASE;

ARTICLE; BINDING AFFINITY; DNA BINDING; DNA DAMAGE; DNA DENATURATION; DNA SUPERCOILING; GENOTOXICITY; HUMAN; LINEAR DICHROISM; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BASE SEQUENCE; BENZIMIDAZOLES; BINDING SITES; DNA; DNA TOPOISOMERASES, TYPE I; ENZYME INHIBITORS; ENZYME STABILITY; ESCHERICHIA COLI; HUMANS; LIGANDS; MALE; NUCLEIC ACID CONFORMATION; RECOMBINANT PROTEINS; SPECTRUM ANALYSIS; THERMODYNAMICS;

EID: 0032502313     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9727747     Document Type: Article

References (44)

1. Potmesil, M., and Pinedo, H. (1995) Camptothecins: New Anticancer Agents, CRC Press, Boca Raton, FL.
2. Hertzberg, R. P., Busby, R. W., Caranfa, M. J., Holden, K. G., Johnson, R. K., Hecht, S. M., and Kingsbury, W. D. (1990) J. Biol. Chem. 265, 19287-19295.
3. Pommier, Y., Kohlhagen, G., Kohn, K. W., Leteurtre, F., Wani, M. C., and Wall, M. E. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 8861-8865.
4. Hsiang, Y.-H., Hertzberg, R., Hecht, S., and Liu, L. F. (1985) J. Biol. Chem. 260, 14873-14878.
5. Hertzberg, R. P., Caranfa, M. J., and Hecht, S. M. (1989) Biochemistry 28, 4629-4638.
6. Porter, S. E., and Champoux, J. J. (1989) Nucleic Acids Res. 17, 8521-8532.
7. Chen, A. Y., Yu, C., Gatto, B., and Liu, L. F. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 8131-8135.
8. Chen, A. Y., Yu, C., Bodley, A., Peng, L. F., and Liu, L. F. (1993) Cancer Res. 53, 1332-1337.
9. Sun, Q., Gatto, B., Yu, C., Liu, A., Liu, L. F., and La Voie, E. J. (1994) Bioorg. Med. Chem. Lett. 4, 2871-2876.
10. Kim, J. S., Gatto, B., Yu, C., Liu, A., Liu, L. F., and LaVoie, E. J. (1996) J. Med. Chem. 39, 992-998.
11. Sun, Q., Gatto, B., Yu, C., Liu, A., Liu, L. F., and LaVoie, E. J. (1995) J. Med. Chem. 38, 3638-3644.
12. Pjura, P. E., Grzeskowiak, K., and Dickerson, R. E. (1987) J. Mol. Biol. 197, 257-271.
13. Spink, N., Brown, D. G., Skelly, J. V.. and Neidle. S. (1994) Nucleic Acids Res. 22, 1607-1612.
14. Teng. M.-K., Usman, N., Frederick, C. A., and Wang. A. H.- J. (1988) Nucleic Acids Res. 16, 2671-2690.
15. Vega, M. C., García Sáez. I., Aymamí, J., Eritja, R., Van Der Marel, G. A., Van Boom, J. H., Rich, A., and Coll, M. (1994) Eur. J. Biochem. 222, 721-726.
16. Clark, G. R., Gray, E. J., Neidle, S., Li, Y.-H., and Leupin, W. (1996) Biochemistry 35, 13745-13752.
17. Parkinson, J. A., Barber, J., Douglas, K. T., Rosamond, J., and Sharpies, D. (1990) Biochemistry 29, 10181-10190.
18. Fede, A., Labhardt, A., Bannwarth, W., and Leupin, W. (1991) Biochemistry 30, 11377-11388.
19. Fede, A., Billeter, M., Leupin, W., and Wüthrich, K. (1993) Structure 1, 177-186.
20. Pilch, D. S., Xu, Z., Sun, Q., LaVoie, E. J., Liu, L. K. Geacintov, N. E., and Breslauer, K. J. (1996) Drug Des. Discuss. 13 (3-4), 115-133.
21. Gatto, B., Sanders, M. M., Yu, C. Wu, H.-Y., Makhey, D., LaVoie, E. J., and Liu, L. F. (1996) Cancer Res. 56, 2795- 2800.
22. Griswold, B. L., Humoller, F. L., and McIntyre, A. R. (1951) Anal. Chem. 23, 192-194.
23. Bodley, A. L., Liu, L. F., Israel, M., Ramakrishnan, S., Yoshihiro, K., Giuliani, F. C., Kirschenbaum, S., Silber, R., and Potmesil, M. (1989) Cancer Res. 49, 5969-5978.
24. Christianson, T. W., Sikorski, R. S., Dante, M., Shero, J. H., and Hieter, P. (1992) Gene 110, 119-122.
25. Marky, L. A., and Breslauer, K. J. (1987) Biopolymers 26, 1601-1620.
26. Geacintov, N. E., Ibanez, V., Rougée, M., and Bensasson, R. V. (1987) Biochemistry 26, 3087-3092.
27. Mudd, C. P., and Berger, R. L. (1988) J. Biochem. Biophys. Methods 17, 171-192.
28. Remeta, D. P., Mudd, C. P., Berger, R. L., and Breslauer, K. J. (1991) Biochemistry 30, 9799-9809.
29. Robinson, A. L. (1932) J. Am. Chem. Soc. 54, 1311-1318.
30. Gulbransen, E. A., and Robinson, A. L. (1934) J. Am. Chem. Soc: 56, 2637-2641.
31. Nordén, B. (1978) Appl. Spectrosc. Rev. 14, 157-248.
32. Nordén, B., Kubista, M., and Kurucsev, T. (1992) Q. Rev. Biophys. 25, 51-170.
33. Wilson, R. W., and Schellman, J. A. (1978) Biopolymers 17, 1235-1248.
34. Geacintov, N. H., Gagliano, A., Ivanovic, V., and Weinstein, I. B. (1978) Biochemistry 17, 5256-5262.
35. Pilch, D. S., Xu, Z., Sun, Q., LaVoie, E. J., Liu, L. F., and Breslauer, K. J. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 13565-13570.
36. Crothers, D. M. (1971) Biopolymers 10, 2147-2160.
37. Snyder, J. G., Hartman, N. G., D'Estantoit, B. L., Kennard, O., Remeta, D. P., and Breslauer, K. J. (1989) Proc. Natl. Acad. Sci. U.S.A. 86, 3968-3972.
38. Chou, W. Y., Marky, L. A., Zaunczkowski, D., and Breslauer, K. J. (1987) J. Biomol. Struct. Dyn. 5, 345-359.
39. Breslauer, K. J., Freire, E., and Straume, M. (1992) Methods Enzymol. 211, 533-567.
40. Pilch, D. S., Kirolos, M. A., Liu, X., Plum, G. E., and Breslauer, K. J. (1995) Biochemistry 34, 9962-9976.
41. Pilch, D. S., Poklar, N., Gelfand, C. A., Law, S. M., Breslauer, K. J., Baird, E. E., and Dervan, P. B. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 8306-8311.
42. Pilch, D. S., Yu, C., Makhey, D., LaVoie, E. J., Srinivasan, A. R., Olson, W. K., Sauers, R. R., Breslauer, K. J., Geacintov, N. E., and Liu, L. F. (1997) Biochemistry 36, 12542-12553.
43. Caserta, M., Amadei, A., Mauro, E. D., and Camilloni, G. (1989) Nucleic Acids Res. 17, 8463-8474.
44. Krogh, S., Mortensen, U. H., Westergaard, O., and Bonven, B. J. (1991) Nucleic Acids Res. 19, 1235-1241.