A role for the amino terminus of human topoisomerase I

Advances in Enzyme Regulation

Volumn 38, Issue 1, 1998, Pages 253-262

  Haluska Jr , Paul ^a   Rubin, Eric H ^a  

^a RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE; DNA TOPOISOMERASE INHIBITOR; HYBRID PROTEIN; NUCLEOLIN; PHOSPHOPROTEIN; RNA BINDING PROTEIN; VIRUS T ANTIGEN;

AMINO TERMINAL SEQUENCE; ANTINEOPLASTIC ACTIVITY; BLOOM SYNDROME; COLORECTAL CANCER; CONFERENCE PAPER; CONFORMATION; DNA STRAND BREAKAGE; DRUG PROTEIN BINDING; GENETICS; HUMAN; METABOLISM; NONHUMAN; OVARY CANCER; PHYSIOLOGY; PROTEIN BINDING; TARGET CELL;

ANTIGENS, POLYOMAVIRUS TRANSFORMING; BLOOM SYNDROME; DNA TOPOISOMERASES, TYPE I; HUMANS; NUCLEIC ACID CONFORMATION; PHOSPHOPROTEINS; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; RNA-BINDING PROTEINS;

EID: 0345368079     PISSN: 00652571     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0065-2571(97)00008-3     Document Type: Conference Paper

References (23)

1. A. Y. CHEN and L. F. LIU, DNA topoisomerases: essential enzymes and lethal targets, Annu. Rev. Pharmacol. Toxicol. 34, 191-218 (1994).
2. Y. POMMIER, Eukaryotic DNA topoisomerase I: genome gatekeeper and its intruders, camptothecins, Sem. Oncol. 23(supp), 3-10 (1996).
3. E. H. RUBIN, T. LI, P. DUAN and L. F. LIU., Cellular resistance to topoisomerase poisons, pp. 243-260. in Drug Resistance. (W. N. HAIT, ed.). Kluwer Academic Publishers, Norwell, MA (1996).
4. L. F. LIU, DNA topoisomerase poisons as antitumor drugs, Annu. Rev. Biochem. 58, 351-375 (1989).
5. F. GOLWASSER, I. BAE, M. VALENTI, K. TORRES and Y. POMMIER, Topoisomerase I-related parameters and camptothecin activity in the colon carcinoma cell lines from the National Cancer Institute Anticancer Screen, Cancer Res. 55, 2116-2121 (1995).
6. E. J. MORRIS and H. M. GELLER, Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase I: evidence for cell cycle-independent toxicity, J. Cell. Biol. 134, 757-770 (1996).
7. A. MERINO, K. R. MADDEN, W. S. LANE, J. J. CHAMPOUX and D. REINBERG, DNA topoisomerase I is involved in both repression and activation of transcription, Nature 365, 227-232 (1993).
8. J. C. WANG, DNA topoisomerases, Annu. Rev. Biochem. 65, 635-692 (1996).
9. A. K. BHARTI, M. O. J. OLSON, D. W. KUFE and E. H. RUBIN, Identification of a nucleolin binding site on human topoisomerase I, J. Biol. Chem. 271, 1993-1997 (1996).
10. E. RUBIN, P. PANTAZIS, A. BHARTI, D. TOPPMEYER, B. GIOVANELLA and D. KUFE, Identification of a mutant human topoisomerase I with intact catalytic activity and resistance to 9-nitro-camptothecin, J. Biol. Chem. 269, 2433-2439 (1994).
11. R. R. YOCUM, S. HANLEY, R. WEST and M. PTASHNE, Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae, Mol. Cell. Biol. 4, 1985-1988 (1984).
12. S. FIELDS and O. SONG, A novel genetic system to detect protein-protein interactions, Nature 340, 245-246 (1989).
13. L. BREEDEN and K. NASMYTH, Regulation of the yeast HO gene, Cold Spring Harb. Symp. Quant. Biol. 50, 643-650 (1985).
14. L. F. LIU and K. G. MILLER, Eukaryotic DNA topoisomerases: two forms of type I DNA topoisomerases from HeLa cell nuclei, Proc. Natl. Acad. Sci. U.S.A. 78, 3487-3491 (1981).
15. J. LAI and W. HERR, Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations, Proc. Natl. Acad. Sci. U.S.A. 89, 6958-6962 (1992).
16. N. TUTEJA, N. W. HUANG, D. SKOPAC, R. TUTEJA, S. HRVATIC, J. ZHANG, S. PONGOR, G. JOSEPH, C. FAUCHER, F. AMALRIC and A. FALASHI, Human DNA helicase IV is nucleolin, an RNA helicase modulated by phosphorylation, Gene 160, 143-148 (1995).
17. L. LIU and J. WANG, Supercoiling of the DNA template during RNA transcription, Proc. Natl. Acad. Sci. U.S.A. 84, 7024-7027 (1987).
18. D. T. SIMMONS, T. MELENDY, D. USHER and B. STILLMAN, Simian virus 40 large T antigen binds to topoisomerase I, Virol. 222, 365-374 (1996).
19. K. WUN-KIM, R. H. UPSON, W. YOUNG and D. T. SIMMONS, The DNA-binding domain of simian virus 40 large T antigen has multiple functions, J. Virol. 67, 7608-7611 (1993).
20. S. GANGLOFF, J. P. MCDONALD, C. BENDIXEN, L. ARTHUR and R. ROTHSTEIN, The yeast type I topoisomerase top3 interacts with Sgsl, a DNA helicase homolog: a potential eukaryotic reverse gyrase, Mol. Cell. Biol. 14, 8391-8398 (1994).
21. P. M. WATT, E. J. LOUIS, R. H. BORTS and I. D. HICKSON, Sgs 1: a eukaryotic homolog of E. Coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation, Cell 81, 253-260 (1995).
22. N. A. ELLIS, J. GRODEN, T-Z. YE, J. STRAUGHEN, D. J. LENNON, S. CIOCCI, M. PROYTCHEVA and J. GERMAN, The Bloom's syndrome gene product is homologous to RecQ helicases, Cell 83, 655-666 (1995).
23. J. LU, J. R. MULLEN, S. J. BRILL, S. KLEFF, A. M. ROMEO and R. STERNGLANZ, Human homologues of yeast helicase, Nature 383(letter), 678 (1996).