Induction of DNA topoisomerase II-mediated DNA cleavage by β-lapacphone and related naphthoquinones

Cancer Research

Volumn 57, Issue 4, 1997, Pages 620-627

  Frydman, Benjamin ^a,c,e   Marton, Laurence J ^b   Sun, Jerry S ^c   Neder, Karen ^c   Witiak, Donald T ^c   Liu, Angela A ^d   Wang, Hui Min ^d   Mao, Yong ^d   Wu, Hong Yan ^d   Sanders, Marilyn M ^d   Liu, Leroy F ^d  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^e S'LIL Pharmaceuticals LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; DNA TOPOISOMERASE (ATP HYDROLYSING); GYRASE INHIBITOR;

ARTICLE; CYTOTOXICITY; DNA CLEAVAGE; DRUG CONFORMATION; DRUG DNA INTERACTION; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; TOXICITY TESTING;

ANTINEOPLASTIC AGENTS, ALKYLATING; CAMPTOTHECIN; DNA; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; HUMANS; MERCAPTOETHANOL; NAPHTHOQUINONES; REVERSE TRANSCRIPTASE INHIBITORS; VITAMIN K; YEASTS;

EID: 17544391279     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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