The glycinergic inhibitory synapse

Cellular and Molecular Life Sciences

Volumn 58, Issue 5-6, 2001, Pages 760-793

  Legendre, P ^a  

^a SORBONNE UNIVERSITÉ   (France)

Author keywords

Glycine clearance; Glycine receptor; Glycine uptake; Inhibitory synapse; Postsynaptic receptor modulation; Receptor channel kinetics; Synaptic current; Synaptic vesicular release; Synaptogenesis

Indexed keywords

4 AMINOBUTYRIC ACID; GLYCINE; GLYCINE RECEPTOR; POSTSYNAPTIC RECEPTOR;

4 AMINOBUTYRIC ACID RELEASE; BRAIN STEM; HUMAN; LOCOMOTION; NEUROMODULATION; NEUROTRANSMISSION; NEUROTRANSMITTER RELEASE; NONHUMAN; REVIEW; SPINAL CORD; SYNAPSE;

ANIMALIA;

EID: 0034973097     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00000899     Document Type: Review

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121. Regional distribution of the cells expressing glycine receptor β subunit mRNA in the rat brain
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123. A single amino acid exchange alters the pharmacology of neonatal rat glycine receptor subunit
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129. Casein kinase 2: An 'eminence grise' in cellular regulation?
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133. Functional properties of strychnine-sensitive glycine receptors expressed in Xenopus oocytes injected with a single mRNA
134. Mutations affecting the glycine receptor agonist transduction mechanism convert the competitive antagonist, picrotoxin, into an allosteric potentiator
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209. 2,3-Butanedione monoxime modifies the glycine-gated chloride current of acutely isolated murine hypothalamic neurons
210. Inhibition of primate spinothalamic tract neurons by spinal glycine and GABA is reduced during central sensitization
211. Modulation of glycine-induced chloride current in acutely dissociated rat periaqueductal gray neurons by mu-opioid agonist DAGO
212. Modulation of hippocampal glycine receptor channels by protein kinase C.
213. α1 adrenoceptor activation potentiates taurine response mediated by protein kinase C in substantia nigra neurons
214. α2-adrenoceptor-mediated enhancement of glycine response in rat sacral dorsal commissural neurons
215. Cross-modulation of glycine-activated Cl- channels by protein kinase C and cAMP-dependent protein kinase in the rat
216. Activation of endogenous protein kinase C enhances currents through alpha 1 and alpha 2 glycine receptor channels
217. Modulation of glycine receptor chloride channels by cAMP-dependent protein kinase in spinal trigeminal neurons
218. cAMP-dependent protein kinase modulation of glycine-activated chloride current in neurons freshly isolated from rat ventral tegmental area
219. Protein kinase A-mediated phosphorylation reduces only the fast desensitizing glycine current in acutely dissociated ventromedial hypothalamic neurons
220. Suppression of taurine response in acutely dissociated substantia nigra neurons by intracellular cyclic AMP
221. Alpha 2 adrenoceptor potentiates glycine receptor-mediated taurine response through protein kinase A in rat substantia nigra neurons
222. α-subunit of CaM-KII increases glycine currents in acutely isolated rat spinal neurons
223. 2+-permeable AMPA receptors in rat spinal neurones
224. N-methyl-D-aspartate enhancement of the glycine response in the rat sacral dorsal commissural neurons
225. 2+ inhibition of type III adenylyl cyclase in vivo
226. The multifunctional calcium/calmodulin-dependent protein kinase: From form to function
227. Modulation of inhibitory and excitatory amino acid receptor ion channels by zinc
228. 2+
229. Patch-clamp analysis of glycine-induced currents in chick ciliary ganglion neurons
230. Modulation by zinc ions of native rat and recombinant human inhibitory glycine receptors
231. Zinc potentiation of the glycine receptor chloride channel is mediated by allosteric pathways
232. Modulation of glycine receptors in retinal ganglion cells by zinc
233. Modulation of glycine-induced currents by zinc and other metal cations in neurons acutely dissociated from the dorsal motor nucleus of the vagus of the rat
234. 2+ binding site on the human glycine receptor α1 subunit
235. 2+
236. 2+ modulation of recombinant human inhibitory glycine receptors
237. High affinity zinc potentiation of inhibitory postsynaptic glycinergic currents in the zebrafish hindbrain
238. High-affinity zinc inhibition of NMDA NR1-NR2A receptors
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241. - current in cultured mouse neurons
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243. A single amino acid determines differences in ethanol actions on strychnine-sensitive glycine receptors
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245. Effects of volatile anesthetics on the kinetics of inhibitory postsynaptic currents in cultured rat hippocampal neurons
246. Positive modulation of human γ-aminobutyric acid type A and glycine receptors by the inhalation anesthetic isoflurane
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250. Glycine enhances the central depressant properties of ethanol in mice
251. Anaesthetic potencies of primary alkanols: Implications for the molecular dimensions of the anaesthetic site
252. - current by ethanol in cultured mouse spinal neurons
253. Ethanol affects the function of a neurotransmitter receptor protein without altering the membrane lipid phase
254. Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors
255. Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position α267
256. Mutations of γ-aminobutyric acid and glycine receptors change alcohol cutoff: Evidence for an alcohol receptor?
257. Specific binding sites for alcohols and anesthetics on ligand-gated ion channels
258. Enhancement of glycine receptor function by ethanol: Role of phosphorylation
259. Effects of acute, chronic ethanol and withdrawal on dorsal raphe neurons: Electrophysiological studies
260. The atypical M2 segment of the beta subunit confers picrotoxinin resistance to inhibitory glycine receptor channels
261. Amino acid transmitters in the mammalian central nervous system
262. Multiple picrotoxinin effect on glycine channels in rat hippocampal neurons
263. Mutations in the α1 subunit of the inhibitory glycine receptor cause the dominant neurologic disorder, hyperekplexia
264. Molecular mechanisms of inherited startle syndromes
265. Startle disease mutations reduce the agonist sensitivity of the human inhibitory glycine receptor
266. Decreased agonist affinity and chloride conductance of mutant glycine receptors associated with human hereditary hyperekplexia
267. Potentiation of chloride responses to glycine by three 5-HT3 antagonists in rat spinal neurones
268. Mode of action of ICS 205,930, a novel type of potentiator of responses to glycine in rat spinal neurones
269. Control of expression of one-carbon metabolism genes of Saccharomyces cerevisiae is mediated by a tetrahydrofolate-responsive protein binding to a glycine regulatory region including a core 5′-CTTCTT-3′ motif
270. Inhibition of glycine currents by dextromethorphan in neurones dissociated from the guinea-pig nucleus tractus solitarii
271. Competitive inhibition of the glycine-induced current by pregnenolone sulfate in cultured chick spinal cord neurons
272. - current of acutely dissociated rat hippocampal neurons
273. Subunit-specific action of an anticonvulsant thiobutyrolactone on recombinant glycine receptors involves a residue in the M2 membrane-spanning region
274. Evidence for recessive as well as dominant forms of startle disease (hyperekplexia) caused by mutations in the alpha 1 subunit of the inhibitory glycine receptor
275. Co-dominant inhefitance of hyperekplexia and spastic paraparesis
276. Deficit of spinal cord glycine/strychnine receptors in inherited myoclonus of Poll Hereford calves
277. Glycine receptor β-subunit gene mutation in spastic mouse associated with LINE-1 element insertion
278. The spastic mouse: Aberrant splicing of glycine receptor β subunit mRNA caused by intronic insertion of L1 element
279. A frameshift mutation in the mouse α1 glycine receptor gene (Glra1) results in progressive neurological symptoms and juvenile death
280. Disorders of the inhibitory glycine receptor: The spastic mouse
281. Spasmodic, a mutation on chromosome 11 in the mouse
282. The frameshift mutation oscillator (Glra1(spd-ot)) produces a complete loss of glycine receptor α1-polypeptide in mouse central nervous system
283. Startle responses in hereditary hyperekplexia
284. Hyperekplexia: Abnormal startle response due to glycine receptor mutations
285. Hyperekplexia mutations of the glycine receptor unmask the inhibitory subsite for β-amino-acids
286. A novel mutation (G1n266→His) in the α1 subunit of the inhibitory glycine-receptor gene (GLRA1) in hereditary hyperekplexia
287. Mutational analysis of familial and sporadic hyperekplexia
288. Analysis of GLRA1 in hereditary and sporadic hyperekplexia: A novel mutation in a family cosegregating for hyperekplexia and spastic paraparesis
289. Properties of human glycine receptors containing the hyperekplexia mutation α1(K276E), expressed in Xenopus oocytes
290. A GLRA 1 null mutation in recessive hyperekplexia challenges the functional role of glycine receptors
291. Saturation of postsynaptic receptors at central synapses?
292. Characterisation of excitatory and inhibitory postsynaptic currents of the rat medial suprior olive in vitro
293. Transmitter timecourse in the synaptic cleft: Its role in central synaptic function
294. The minimal inhibitory synaptic current evoked in neonatal rat motoneurones
295. Glycinergic inhibitory synaptic currents and related receptor channels in the zebrafish brain
296. Origin of variability in quantal size in cultured hippocampal neurons and hippocampal slices
297. Quantal analysis of inhibitory synaptic transmission in the dentate gyrus of rat hippocampal slices: A patch-clamp study
298. Postsynaptic contribution to long-term potentiation revealed by the analysis of miniature synaptic currents
299. Rapid-time-course miniature and evoked excitatory currents at cerebellar synapses in situ
300. Saturation of postsynaptic glutamate receptors after quantal release of transmitter
301. Spontaneous quantal currents in a central neuron match predictions from binomial analysis of evoked responses
302. Differences in synaptic GABA(A) receptor number underlie variation in GABA mini amplitude
303. Quantal size is correlated with receptor cluster area at glycinergic synapses in the rat brainstem
304. Long-term potentiation of glycinergic inhibitory synaptic transmission
305. 'Latent' inhibitory connections become functional during activity-dependent plasticity
306. Giant synaptic potentials in immature rat CA3 hippocampal neurones
307. Mechanisms of GABA and glycine depolarization-induced calcium transients in rat dorsal horn neurons
308. Development of glycinergic and glutamatergic synaptic transmission in the auditory brainstem of perinatal rats
309. Spontaneous motoneuronal activity mediated by glycine and GABA in the spinal cord of rat fetuses in vitro
310. Glycine-activated currents are changed by coincident membrane depolarization in developing rat auditory brainstem neurones
311. 2+ transients in embryonic rat dorsal horn neurons in culture
312. Early development of glycine- and GABA-mediated synapses in rat spinal cord
313. Excitatory GABA responses in embryonic and neonatal cortical slices demonstrated by gramicidin perforated-patch recordings and calcium imaging
314. An intracellular analysis of γ-aminobutyric-acid-associated ion movements in rat sympathetic neurones
315. A receptor-mediated responses in spinal neurons
316. Development of GABA-mediated, chloride-dependent inhibition in CA1 pyramidal neurones of immature rat hippocampal slices
317. - co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation
318. Postnatal change of glycinergic IPSC decay in sympathetic preganglionic neurons
319. Biology of the postsynaptic glycine receptor
320. Distribution and lateral mobility of GABA/benzodiazepine receptors on nerve cells
321. Distribution and lateral mobility of glycine receptors on cultured spinal cord neurons
322. Clustering and mobility of voltage-dependent sodium channels during myelination
323. Ligand binding regulates the directed movement of beta1 integrins on fibroblasts
324. The inhibitory glycine receptor: Prospects for a therapeutic orphan
325. Cyanotriphenylborate: Subtype-specific blocker of glycine receptor chloride channels
326. Actions of 3-[2-phosphonomethyl[1,1-biphenyl]-3-y1]alanine (PMBA) on cloned glycine receptors
327. AR)-associated protein synapse
328. Fast and Reversible trapping of surface glycine receptors by gephyrin