Kinetic analysis of glycine receptor currents in ventral cochlear nucleus

Journal of Neurophysiology

Volumn 79, Issue 4, 1998, Pages 1891-1901

  Harty, T Patrick ^a,b   Manis, Paul B ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCINE; GLYCINE RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; COCHLEAR NUCLEUS; FEMALE; GUINEA PIG; KINETICS; MALE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION;

EID: 0031946342     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1998.79.4.1891     Document Type: Article

References (79)

1. ADAMS, P. R. A study of desensitization using voltage clamp. Pflügers Arch. 360: 135-144, 1975.
2. AGOPYAN, N., TOKUTOMI, N., AND AKAIKE, N. Protein kinase A-mediated phosphorylation reduces only the fast desensitizing glycine current in acutely dissociated ventromedial hypothalamic neurons. Neuroscience 56: 605-615, 1993.
3. AKAIKE, N. AND KANEDA, M. Glycine-gated chloride current in acutely isolated rat hypothalamic neurons. J. Neurophysiol. 62: 1400-1409, 1989.
4. ALTSCHULER, R. A., BETZ, H., PARAKKAL, M. H., REEKS, K. A., AND WENTHOLD, R. J. Identification of glycinergic synapses in the cochlear nucleus through immunocytochemical localization of the postsynaptic receptor. Brain Res. 369: 316-320, 1986.
5. ARAKI, T., ITO, M., AND OSCARSSON, O. Anion permeability of the synaptic and non-synaptic motoneurone membrane. J. Physiol. (Lond.) 159: 410-435, 1961.
6. 3H]glycine from the cochlear nucleus to the superior olive in the guinea pig. J. Comp. Neurol. 296: 415-426, 1990.
7. BERTRAND, D. AND BADER, C. R. DATAC: a multipurpose biological data analysis program based on a mathematical interpreter. Int. J. Biomed. Comput. 18: 193-202, 1986.
8. BETZ, H. Ligand-gated ion channels in the brain: the amino acid receptor superfamily. Neuron 5: 383-392, 1990.
9. BLACKBURN, C. C. AND SACHS, M. B. The representation of the steady-state vowel sound/e/in the discharge pattern of cat anteroventral cochlear nucleus neurons. J. Neurophysiol. 68: 124-143, 1990.
10. BRUGHERA, A., STUTMAN, E., CARNEY, L., AND COLBURN, S. A model with excitation and inhibition for cells in the medial superior olive. Auditory Neurosci. 2: 219-233, 1996.
11. CASPARY, D. M., BACKOFF, P. M., FINLAYSON, P. G., AND PALOMBI, P. S. Inhibitory inputs modulate discharge rate within frequency receptive fields of anteroventral cochlear nucleus neurons. J. Neurophysiol. 72: 2124-2133, 1994.
12. CASPARY, D. M., HAVEY, D. C., AND FAINGOLD, C. L. Effects of microiontophoretically applied glycine and GABA on neuronal response patterns in the cochlear nuclei. Brain Res. 172: 179-185, 1979.
13. A receptor in outside-out patches. Biophys. J. 66: 1039-1050, 1994.
14. CLEMENTS, J. D. Transmitter timecourse in the synaptic cleft: its role in central synaptic function. Trends Neurosci. 19: 163-171, 1996.
15. CLEMENTS, J. D., LESTER, R. A., TONG, G., JAHR, C. E., AND WESTBROOK, G. L. The time course of glutamate in the synaptic cleft. Science 258: 1498-1501, 1992.
16. COOMBS, J. S., ECCLES, J. C., AND FATT, P. The specific ionic conductances and the ionic movements across the motoneuronal membrane that produce the inhibitory post-synaptic potential. J. Physiol. (Lond.) 130: 326-373, 1955.
17. COREY, D. P. AND HUDSPETH, A. J. Mechanical stimulation and micromanipulation with piezoelectric bimorph elements. J. Neurosci. Methods 3: 183-202, 1980.
18. CURTIS, D. R., HÖSLI, L., JOHNSTON, G.A.R., AND JOHNSTON, I. H. The hyperpolarization of spinal motoneurones by glycine and related amino acids. Exp. Brain. Res. 5: 235-258, 1968.
19. FABER, D. S., YOUNG, W. S., LEGENDRE, P., AND KORN, H. Intrinsic quantal variability due to stochastic properties of receptor-transmitter interactions. Science 258: 1494-1498, 1992.
20. FATIMA-SHAD, K. AND BARRY, P. H. A patch-clamp study of GABA- and strychnine-sensitive glycine-activated currents in post-natal tissue-cultured hippocampal neurons. Proc. R. Soc. Lond. B Biol. Sci. 250: 99-105, 1992.
21. FRANKE, C., HATT, H., AND DUDEL, J. Liquid filament switch for ultra-fast exchanges of solutions at excised patches of synaptic membrane of crayfish muscle. Neurosci. Lett. 77: 199-204, 1987.
22. FROSTHOLM, A. AND ROTTER, A. Autoradiographic localization of receptors in the cochlear nucleus of the mouse. Brain Res. Bull. 16: 189-203, 1986.
23. GALARRETA, M. AND HESTRIN, S. Properties of GABAA receptors underlying inhibitory synaptic currents in neocortical pyramidal neurons. J. Neurosci. 17: 7220-7227, 1997.
24. 2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS. Neuron 15: 193-204, 1995.
25. GODFREY, D. A., CARTER, J. A., BERGER, S. J., LOWRY, O. H., AND MATSCHINSKY, F. M. Quantitative histochemical mapping of candidate transmitter amino acids in cat cochlear nucleus. J. Histochem. Cytochem. 25: 417-431, 1977.
26. GRENNINGLOH, G., PRIBILLA, I., PRIOR, P., MULTHAUP, G., BEYREUTHER, K., TALEB, O., AND BETZ, H. Cloning and expression of the 58 kd B subunit of the inhibitory glycine receptor. Neuron 4: 963-970, 1990.
27. GRENNINGLOH, G., RIENITZ, A., SCHMITT, B., METHFESSEL, C., ZENSEN, M., BEYREUTHER, K., GUNDELFINGER, E. D., AND BETZ, H. The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptors. Nature 328: 215-220, 1987.
28. GROTHE, B. AND SANES, D. H. Synaptic inhibition influences the temporal coding properties of medial superior olivary neurons: an in vitro study. J. Neurosci. 14: 1701-1709, 1994.
29. GUNDERSEN, C. B., MILEDI, R., AND PARKER, I. Properties of human brain glycine receptors expressed in Xenopus oocytes. Proc. R. Soc. Lond. B Biol. Sci. 221: 235-244, 1984.
30. HARTY, T. P. AND MANIS, P. B. Glycine-evoked currents in acutely dissociated neurons of the guinea pig ventral cochlear nucleus. J. Neurophysiol. 75: 2300-2311, 1996.
31. ITO, M., KOSTYUK, P. G., AND OSHIMA, T. Further study on anion permeability of inhibitory post-synaptic membrane of cat motoneurones. J. Physiol. (Lond.) 164: 150-156, 1962.
32. ITO, S. AND CHERUBINI, E. Strychnine-sensitive glycine responses of neonatal rat hippocampal neurones. J. Physiol. (Lond.) 440: 67-83, 1991.
33. A channel responses to brief agonist pulses. Neuron 15: 181-191, 1995.
34. KAKEHATA, S., NAKAGAWA, T., TAKASAKA, T., AND AKAIKE, N. Glycine response in isolated dorsal cochlear nucleus of C57BL/6J mouse. Brain Res. 574: 21-25, 1992.
35. KIRSCH, J., LANGOSCH, D., PRIOR, P., LITTAUER, U. Z., SCHMITT, B., AND BETZ, H. The 93-kDa glycine receptor-associated protein binds to tubulin. J. Biol. Chem. 266: 22242-22245, 1991.
36. KUHSE, J., BETZ, H., AND KIRSCH, J. The inhibitory glycine receptor: architecture, synaptic localization and molecular pathology of a postsynaptic ion-channel complex. Curr. Opin. Neurobiol. 5: 318-323, 1995.
37. KUHSE, J., KURYATOV, A., MAULET, Y., MALOSIO, M. L., SCHMIEDEN, V., AND BETZ, H. Alternative splicing generates two isoforms of the alpha 2 subunit of the inhibitory glycine receptor. FEBS Lett. 283: 73-77, 1991.
38. 2+. J. Neurophysiol. 76: 227-241, 1996.
39. LAI, Y.-C., WINSLOW, R., AND SACHS, M. The functional role of excitatory and inhbitory interactions in chopper cells of the anteroventral cochlear nucleus. Neural Comput. 6: 1127-1140, 1994a.
40. LAI, Y.-C., WINSLOW, R., AND SACHS, M. A model of selective processing of auditory-nerve inputs by stellate cells of the antero-ventral cochlear nucleus. J. Comput. Neurosci. 1: 167-194, 1994b.
41. LANGOSCH, D., BECKER, C., AND BETZ, H. The inhibitory glycine receptor: a ligand-gated chloride channel of the central nervous system. Eur. J. Biochem. 194: 1-8, 1990.
42. LAUBE, B., KUHSE, J., RUNDSTROM, N., KIRSCH, J., SCHMIEDEN, V., AND BETZ, H. Modulation by zinc ions of native rat and recombinant human inhibitory glycine receptors. J. Physiol. (Lond.) 483: 613-619, 1995.
43. LEWIS, C. A., AHMED, Z., AND FABER, D. S. A characterization of glycinergic receptors present in cultured rat medullary neurons. J. Neurophysiol. 66: 1291-1303, 1991.
44. MALOSIO, M. L., GRENNINGLOH, G., KUHSE, J., SCHMIEDEN, V., SCHMITT, B., PRIOR, P., AND BETZ, H. Alternative splicing generates two variants of the alpha 1 subunit of the inhibitory glycine receptor. J. Biol. Chem. 266: 2048-2053, 1991.
45. MCNIVEN, A. I. AND MARTIN, A. R. Effect of cytoplasmic chloride concentration on open-state preference of glycine-activated chloride channels in cultured spinal cord cells. J. Neurophysiol. 69: 860-867, 1993.
46. MELNICK, I. V. AND BAEV, K. V. Glycine conductance changes in chick spinal cord neurons developing in culture. Neuroscience 52: 347-360, 1993.
47. OERTEL, D. Synaptic responses and electrical properties of cells in brain slices of the mouse anteroventral cochlear nucleus. J. Neurosci. 3: 2043-2053, 1983.
48. OTIS, T. S., RAMAN, I. M., AND TRUSSELL, L. O. AMPA receptors with Ca2+ permeability mediate synaptic transmission in the avian auditory pathway. J. Physiol. (Lond.) 482: 309-315, 1995.
49. PFEIFFER, F., GRAHAM, D., AND BETZ, H. Purification by affinity chromatography of the glycine receptor of rat spinal cord. J. Biol. Chem. 257: 9389-9393, 1982.
50. PRIBILLA, I., TAKAGI, T., LANGOSCH, D., BORMANN, J., AND BETZ, H. The atypical M2 segment of the β subunit confers picrotoxinin resistance to inhibitory glycine receptor channels. EMBO J. 11: 4305-4311, 1992.
51. RAMAN, I. M. AND TRUSSELL, L. O. The kinetics of the response to glutamate and kainate in neurons of the avian cochlear nucleus. Neuron 9: 173-186, 1992.
52. ROBERTSON, D. Physiology and morphology of cells in the ventral nucleus of trapezoid body and reostral periolivary regions of the rat superior olivary complex studied in slices. Auditory Neurosci. 2: 15-31, 1996.
53. ROTHMAN, J. S., YOUNG, E. D., AND MANIS, P. B. Convergence of auditory nerve fibers onto bushy cells in the ventral cochlear nucleus: implications of a computational model. J. Neurophysiol. 70: 2562-2583, 1993.
54. SAINT MARIE, R. L., BENSON, C. G., OSTAPOFF, E.-M., AND MOREST, D. K. Glycine immunoreactive projections from the dorsal to the anteroventral cochlear nucleus. Hear. Res. 51: 11-28, 1991.
55. SANES, D. H. An in vitro analysis of sound localization mechanisms in the gerbil lateral superior olive. J. Neurosci. 10: 3494-506, 1990.
56. SATO, K., KURIYAMA, H., AND ALTSCHULER, R. A. Expression of glycine receptor subunits in the cochlear nucleus and superior olivary complex using non-radioactive in-situ hybridization. Hear. Res. 91: 7-18, 1995.
57. SCHMIEDEN, V., GRENNINGLOH, G., SCHOFIELD, P. R., AND BETZ, H. Functional expression in Xenopus oocytes of the strychnine binding 48 kd subunit of the glycine receptor. EMBO J. 8: 695-700, 1989.
58. SCUKA, M. AND MOZRZYMAS, J. W. Postsynaptic potentiation and desensitization at the vertebrate end-plate receptors. Prog. Neurobiol. 38: 19-33, 1992.
59. SONG, Y. AND HUANG, L.-Y.M. Modulation of glycine receptor chloride channels by cAMP-dependent protein kinase in spinal trigeminal neurons. Nature 348: 242-245, 1990.
60. TITMUS, M. J., KORN, H., AND FABER, D. S. Diffusion, not uptake, limits glycine concentration in the synaptic cleft. J. Neurophysiol. 75: 1738-1752, 1996.
61. UNWIN, N. The structure of ion channels in membranes of excitable cells. Neuron 3: 665-676, 1989.
62. VAELLO, M. L., RUIZ-GOMEZ, A., LERMA, J., AND MAYOR, F., JR. Modulation of inhibitory glycine receptors by phosphorylation by protein kinase C and cAMP-dependent protein kinase. J. Biol. Chem. 269: 2002-2008, 1994.
63. VAN DEN POL, A. N. AND GORCS, T. Glycine and glycine receptor immunoreactivity in brain and spinal cord. J. Neurosci. 8: 472-492, 1988.
64. WAHL, L. M., POUZAT, C., AND STRATFORD, K. J. Monte Carlo simulation of fast excitatory synaptic transmission at a hippocampal synapse. J. Neurophysiol. 75: 597-608, 1996.
65. WANG, R. A. AND RANDIC, M. α-Subunit of CAM-KII increases glycine currents in acutely isolated rat spinal neurons. J. Neurophysiol. 75: 2651-2653, 1996.
66. WANG, X. AND SACHS, M. Transformation of temporal discharge patterns in a ventral cochlear nucleus stellate cell model: implications for physiological mechanisms. J. Neurophysiol. 73: 1600-1616, 1995.
67. WENTHOLD, R. J. Evidence for a glycinergic pathway connecting the two cochlear nuclei: an immunocytochemical and retrograde transport study. Brain Res. 415: 183-187, 1987.
68. WENTHOLD, R. J., PARAKKAL, M. H., OBERDORFER, M. D., AND ALTSCHULER, R. A. Glycine receptor immunoreactivity in the ventral cochlear nucleus of the guinea pig. J. Comp. Neurol. 276: 423-435, 1988.
69. WERMAN, R., DAVIDOFF, R. A. AND APRISON, M. H. Inhibitory action of glycine on spinal neurons in the cat. J. Neurophysiol. 31: 81-95, 1968.
70. WICKESBERG, R. Rapid inhibition in the cochlear nuclear complex of the chinchilla. J. Acoust. Soc. Am. 100: 1691-1702, 1996.
71. WICKESBERG, R. E. AND OERTEL, D. Tonotopic projection from the dorsal to the anteroventral cochlear nucleus of mice. J. Comp. Neurol. 268: 389-399, 1988.
72. WICKESBERG, R. E. AND OERTEL, D. Delayed, frequency-specific inhibition in the cochlear nuclei of mice: a mechanism for monaural echo suppression. J. Neurosci. 10: 1762-1768, 1990.
73. WINSLOW, R. L., BARTA, P. E., AND SACHS, M. B. Rate coding in the auditory nerve. In: Auditory Processing of Complex Sounds, edited by C. S. Watson and W. Yost. Hillsdale, NJ: Erlbaum, 1987, p. 212-224.
74. WU, S. AND KELLY, J. Binaural interaction in the lateral superior olive: time difference sensitivity studied in mouse brain slice. J. Neurophysiol. 68: 1151-1159, 1992.
75. WU, S. AND KELLY, J. In vitro brain slice studies of the rat's dorsal nucleus of the lateral lemniscus. I. Membrane and synaptic response properties. J. Neurophysiol. 73: 780-793, 1995a.
76. WU, S. AND KELLY, J. Inhibition in the superior olivary complex: pharmacological evidence from mouse brain slice. J. Neurophysiol. 73: 256-269, 1995b.
77. WU, S. H. AND OERTEL, D. Inhibitory circuitry in the ventral cochlear nucleus is probably mediated by glycine. J. Neurosci. 6: 2691-2706, 1986.
78. YIN, T.C.T. AND CHAN, J. C. Interaural time sensitivity in medial superior olive of cat. J. Neurophysiol. 64: 465-488, 1990.
79. ZHOU, N., TAYLOR, D. A., AND PARKS, T. N. Cobalt-permeable non-NMDA receptors in developing chick brainstem auditory nuclei. Neuroreport 6: 2273-2276, 1995.