Glycine triggers an intracellular calcium influx in oligodendrocyte progenitor cells which is mediated by the activation of both the ionotropic glycine receptor and Na+-dependent transporters

European Journal of Neuroscience

Volumn 12, Issue 6, 2000, Pages 1924-1930

  Belachew, Shibeshih ^a,b   Malgrange, Brigitte ^a   Rigo, Jean Michel ^a   Register, Bernard ^a,b   Leprince, Pierre ^a   Hans, Gregory ^a   Nguyen, Laurent ^a   Moonen, Gustave ^a,b  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Calcium imaging; Fluo 3; Rat cerebral cortex

Indexed keywords

CALCIUM; CARRIER PROTEIN; GLYCINE; GLYCINE RECEPTOR; SODIUM ION;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; NERVE GROWTH; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; STEM CELL;

AMINO ACID TRANSPORT SYSTEMS, NEUTRAL; ANIMALS; BICUCULLINE; BIOLOGICAL TRANSPORT; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CARRIER PROTEINS; CELL COMMUNICATION; GABA ANTAGONISTS; GLYCINE; GLYCINE AGENTS; GLYCINE PLASMA MEMBRANE TRANSPORT PROTEINS; NEUROBLASTOMA; NEURONS; NIFEDIPINE; OLIGODENDROGLIA; RATS; SODIUM; STEM CELLS; STRYCHNINE; TUMOR CELLS, CULTURED;

EID: 0034082350     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2000.00085.x     Document Type: Article

References (39)

1. Adams, R.H., Sato, K., Shimada, S., Tohyama, M., Pschel, A.W. & Betz, H. (1995) Gene structure and glial expression of the glycine transporter GlyT1 in embryonic and adult rodents. J. Neurosci., 15, 2524-2532.
2. Aragon, M.C., Gimenez, C. & Mayor, F. (1987) Stoichiometry of sodium-and chloride-coupled glycine transport in synaptic plasma membrane vesicles derived from rat brain. FEBS Lett., 212, 87-90.
3. Avellana-Adalid, V., Nait Oumesmar, B., Lachapelle, F. & Baron-Van Evercooren, A. (1996) Expansion of rat oligodendrocyte progenitors into proliferative 'oligospheres' that retain differentiation potential. J. Neurosci. Res., 45, 558-570.
4. Belachew, S., Malgrange, B., Rigo, J.-M., Rogister, B., Coucke, P., Mazy-Servais, C. & Moonen, G. (1998a) Developmental regulation of neuroligand-induced responses in cultured oligodendroglia. Neuroreport, 9, 973-980.
5. Belachew, S., Register, B., Rigo, J.-M., Malgrange, B., Mazy-Servais, C., Xhauflaire, G., Coucke, P. & Moonen, G. (1998b) Cultured oligodendrocyte progenitors derived from cerebral cortex express a glycine receptor which is pharmacologically distinct from the neuronal isoform. Eur. J. Neurosci., 10, 3556-3564.
6. Borowsky, B., Mezey, E. & Hoffman, B.J. (1993) Two glycine transporter variants with distinct localization in the CNS and peripheral tissues are encoded by a common gene. Neuron, 10, 851-863.
7. Calver, A.R., Hall, A.C., Yu, W.P., Walsh, F.S., Heath, J.K., Betsholtz, C. & Richardson, W.D. (1998) Oligodendrocyte population dynamics and the role of PDGF in vivo. Neuron, 20, 869-882.
8. Chattopadhyay, N., Ye, C.P., Yamaguchi, T., Kifor, O., Vassilev, P.M., Nishimura, R. & Brown, E.M. (1998) Extracellular calcium-sensing receptor in rat oligodendrocytes: Expression and potential role in regulation of cellular proliferation and an outward K + channel. Glia, 24, 449-158.
9. Cohen, R.I. & Almazan, G. (1993) Norepinephrine-stimulated PI hydrolysis in oligodendrocytes is mediated by alpha 1A-adrenoceptors. Neuroreport, 4, 1115-1118.
10. Cohen, R.I. & Almazan, G. (1994) Rat oligodendrocytes express muscarinic receptors coupled to phosphoinositide hydrolysis and adenylyl cyclase. Eur. J. Neurosci., 6, 1213-1224.
11. Demerens, C., Stankoff, B., Logak, M., Anglade, P., Allinquant, B., Couraud, F., Zalc, B. & Lubetzki, C. (1996) Induction of myelination in the central nervous system by electrical activity. Proc. Natl Acad. Sci. USA, 93, 9887-9892.
12. Flint, A.C., Liu, X.L. & Kriegstein, A.R. (1998) Nonsynaptic glycine receptor activation during early neocortical development. Neuron, 20, 43-53.
13. Gilbert, P., Kettenmann, H. & Schachner, M. (1984) Gamma-aminobutyric acid directly depolarizes cultured oligodendrocytes. J. Neurosci., 4, 561-569.
14. Guastella, J., Brecha, N., Weigmann, C., Lester, H.A. & Davidson, N. (1992) Cloning, expression, and localization of a rat brain high-affinity glycine transporter. Proc. Natl Acad. Sci. USA, 89, 7189-7193.
15. He, M.H., Howe, D.G. & McCarthy, K.D. (1996) Oligodendroglial signal transduclion systems are regulated by neuronal contact. J. Neurochem., 67, 1491-1499.
16. Holtzclaw, L.A., Gallo, V. & Russell, J.T. (1995) AMPA receptors shape calcium responses in cortical oligodendrocyte progenitors and CG-4 cells. J. Neurosci. Res., 42, 124-130.
17. Hoppe, D. & Kettenmann, H. (1989) GABA triggers a chloride efflux from cultured oligodendrocytes. Neurosci. Lett., 97, 334-339.
18. Jursky, F. & Nelson, N. (1995) Localization of glycine neurotransmitter transporter (GLYT2) reveals correlation with the distribution of glycine receptor. J. Neurochem., 64, 1026-1033.
19. Kim, K.M., Kingsmore, S.F., Han, H., Yang-Feng, T.L., Godinot, N., Seldin, M.F., Caron, M.G. & Giros, B. (1994) Cloning of the human glycine transporter type 1: molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomes. Mol. Pharmacol., 45, 608-617.
20. Kirchhoff, F. & Kettenmann, H. (1992) GABA triggers a [Ca 2+]i increase in murinc precursor cells of the oligodendrocyte lineage. Eur. J. Neurosci., 4, 1049-1058.
21. Kirchhoff, F., Mulhardt, C., Pastor, A., Becker, C.-M. & Kettenmann, H. (1996) Expression of glycine receptor subunits in glial cells of the rat spinal cord. J. Neurochem., 4, 1383-1390.
22. Kirischuk, S., Scherer, J., Kettenmann, H. & Verkhratsky, A. (1995a) Activation of P2 -purinoreceptors triggered Ca 2+ release from InsP3 -sensitive internal stores in mammalian oligodendrocytes. J. Physiol. (London), 483, 41-57.
23. Kirischuk, S., Scherer, J., Möller, T., Verkhratsky, A. & Kettenmann, H. (1995b) Subcellular heterogeneity of voltage-gated Ca 2+ channels in cells of the oligodendrocyte lineage. Glia, 13, 1-12.
24. Knutson, P., Ghiani, C.A., Zhou, J.M., Gallo, V. & McBain, C.J. (1997) K + channel expression and cell proliferation are regulated by intracellular sodium and membrane depolarization in oligodendrocyte progenitor cells. J. Neurosci., 17, 2669-2682.
25. Liu, Q.R., Löpez-Corcuera, B., Mandiyan, S., Nelson, H. & Nelson, N. (1993) Cloning and expression of a spinal cord-and brain-specific glycine transporter with novel structural features. J. Biol. Chem, 268, 22802-22808.
26. Liu, Q.R., Nelson, H., Mandiyan, S., Löpez-Corcuera, B. & Nelson, N. (1992) Cloning and expression of a glycine transporter from mouse brain. FEBS Lett., 305, 110-114.
27. Löpez-Corcuera, B., Martínez-Maza, R., Núnez, E., Roux, M., Supplisson, S. & Aragón, C. (1998) Differential properties of two stably expressed brain-specific glycine transporters. J. Neurochem., 71, 2211-2219.
28. Luque, J.M., Nelson, N. & Richards, J.G. (1995) Cellular expression of glycine transporter 2 messenger RNA exclusively in rat hindbrain and spinal cord. Neuroscience, 64, 525-535.
29. Morrow, J.A., Collie, I.T., Dunbar, D.R., Walker, G.B., Shahid, M. & Hill, D.R. (1998) Molecular cloning and functional expression of the human glycine transporter GlyT2 and chromosomal localisation of the gene in the human genome. FEBS Lett., 439, 334-340.
30. Pende, M., Fisher, T.L., Simpson, P.B., Russell, J.T., Blenis, J. & Gallo, V. (1997) Neurotransmitter-and growth factor-induced cAMP response element binding protein phosphorylalion in glial cell progenitors: role of calcium ions, protein kinase C, and mitogen-activated protein kinase/ ribosomal S6 kinase pathway. J. Neurosci., 17, 1291-1301.
31. Poyatos, I., Ponce, J., Aragon, C., Gimenez, C. & Zafra, F. (1997) The glycine transporter GLYT2 is a reliable marker for glycine-immunoreactive neurons. Brain Res. Mol. Brain Res., 49, 63-70.
32. Sato-Bigbee, C., Pal, S. & Chu, A.K. (1999) Different neuroligands and signal transduction pathways stimulate CREB phosphorylation at specific developmental stages along oligodendrocyte differentiation. J. Neurochem., 72, 139-147.
33. Smith, K.E., Borden, L.A., Hartig, P.R., Branchek, T. & Weinshank, R.L. (1992) Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors. Neuron, 8, 927-935.
34. Takeda, M., Nelson, D.J. & Soliven, B. (1995) Calcium signaling in cultured rat oligodendrocytes. Glia, 14, 225-236.
35. Verkhratsky, A., Orkand, R.K. & Kettenmann, H. (1998) Glial calcium: Homeostasis and signaling function. Physiol. Rev., 78, 99-141.
36. Von Blankenfeld, G., Verkhratsky, A. & Kettenmann, H. (1992) Calcium channel expression in the oligodendrocyte lineage. Eur. J. Neurosci., 4, 1035-1048.
37. Zafra, F., Aragon, C., Olivares, L., Danbolt, N.C., Gimenez, C. & Storm-Mathisen, J. (1995a) Glycine transporters are differentially expressed among CNS cells. J. Neurosci., 15, 3952-3969.
38. Zafra, F., Gomeza, J., Olivares, L., Aragon, C. & Gimenez, C. (1995b) Regional distribution and developmental variation of the glycine transporters GLYT1 and GLYT2 in the rat CNS. Eur J. Neurosci., 7, 1342-1352.
39. Zafra, F., Poyatos, I. & Gimenez, C. (1997) Neuronal dependency of the glycine transporter GLYT1 expression in glial cells. Glia, 20, 155-162.