α-Subunit of CaM-KII increases glycine currents in acutely isolated rat spinal neurons

Journal of Neurophysiology

Volumn 75, Issue 6, 1996, Pages 2651-2653

  Wang, Rong A ^a   Randić, Mirjana ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALPAIN; GLYCINE RECEPTOR; PROTEIN KINASE (CALCIUM,CALMODULIN);

ALPHA CHAIN; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CELL ISOLATION; CHANNEL GATING; COVALENT BOND; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; NEUROTRANSMITTER RELEASE; NONHUMAN; PATCH CLAMP; POSTSYNAPTIC MEMBRANE; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; SPINAL CORD DORSAL HORN; SPINAL NERVE;

EID: 0029904308     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1996.75.6.2651     Document Type: Article

References (25)

1. BARKER, J. L. AND NICOLL, R. A. The pharmacology and ionic dependency of amino acid responses in the frog spinal cord. J. Physiol. Lond. 228: 259-277, 1973.
2. 2+/calmodulin kinase (CaM) in the caudal medulla and spinal cord: specific labelling of the corticospinal tract. Soc. Neurosci. Abstr. 12: 444, 1986.
3. BENNETT, M. K. AND KENNEDY, M. B. Deduced primary structure of the β subunit of brain type II calcium/calmodulin-dependent protein kinase determined by molecular cloning. Proc. Natl. Acad. Sci. USA 84: 1794-1798, 1987.
4. 2+/ calmodulin protein kinase gene expression in the rat central nervous system. Neuroscience 46: 825-849, 1992.
5. BETZ, H. Glycine receptors: heterogeneous and widespread in the mammalian brain. Trends Neurosci. 14: 458-461, 1991.
6. BORMANN, J., HAMILL, O. P., AND SAKMANN, B. Mechanism of anion permeation through channels gated by glycine and gamma-aminobutyric acid in mouse cultured spinal neurones. J. Physiol. Lond. 385: 243-286, 1987.
7. CURTIS, D. R., HÖSLI, L. AND JOHNSTON, G. A. R. Inhibition of spinal neurons by glycine. Nature Lond. 215: 1502-1503, 1967.
8. 2+/calmodulin-dependent protein kinases. Annu. Rev. Biochem. 61: 559-601, 1992.
9. KENNEDY, M. B., BENNETT, M. K., AND ERONDU, N. E. Biochemical and immunochemical evidence that the "major postsynaptic density protein" is a subunit of a calmodulin-dependent protein kinase. Proc. Natl. Acad. Sci. USA 80: 7357-7361, 1983.
10. KOLAJ, M., CERNE, R., AND RANDIĆ, M. The opioid peptide dynorphin modulates AMPA and kainate responses in acutely isolated neurons from the dorsal horn. Brain Res. 671: 227-244, 1995.
11. LANGOSCH, D., HOCH, W., AND BETZ, H. The 93kDa protein gephyrin and tubulin associated with the inhibitory glycine receptor are phosphorylated by an endogenous protein kinase. FEBS Lett, 298: 113-117, 1992.
12. LANGOSCH, D., THOMAS, L., AND BETZ, H. Conserved quaternary structure of ligand-gated ion channels: the postsynaptic glycine receptor is a pentamer. Proc. Natl Acad. Sci. USA 85: 7394-7398, 1988.
13. LIN, C. R., KAPILOFF, M. S., DURGERIAN, S., TATEMOTO, K., Russo, A. F., HANSON, P., SCHULMAN, H., AND ROSENFELD, M. G. Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase. Proc. Natl Acad. Sci. USA 84: 5962-5966, 1987.
14. MCGLADE-MCCULLOH, E., YAMAMOTO, H., TAN, S.-E., BRICKEY, D. A., AND SODERLING, T. R. Phosphorylation and regulation of glutamate receptors by calcium/calmodulin-dependent protein kinase II. Nature Lond. 362: 640-642, 1993.
15. RAYMOND, L. A., BLACKSTONE, C. D., AND HUGANIR, R. L. Phosphorylation of amino acid neurotransmitter receptors in synaptic plasticity. Trends Neurosci. 16: 147-153, 1993.
16. RUIZ-GOMEZ, A., VAELLO, M. L., VALDIVIESO, F., AND MAYOR, F., JR. Phosphorylation of the 48-kDa subunit of the glycine receptor by protein kinase C. J. Biol. Chem. 266: 559-566, 1991.
17. SONG, Y. M. AND HUANG, L.-Y. M. Modulation of glycine receptor chloride channels by cAMP-dependent protein kinase in spinal trigeminal neurons. Nature Lond. 348: 242-245, 1990.
18. TODD, A. J. An electron microscope study of glycine-like immunoreactivity in laminae I-III of the spinal dorsal horn of the rat. Neuroscience 39: 387-394, 1990.
19. VAELLO, M. L., RUIZ-GOMEZ, A., LERMA, J., AND MAYOR, F., JR. Modulation of inhibitory glycine receptors by phosphorylation by protein kinase C and cAMP-dependent protein kinase. J. Biol. Chem. 269: 2002-2008, 1994.
20. WALAAS, S. I. AND GREENGARD, P. Protein phosphorylation and neuronal function. Pharmacol. Rev. 43: 299-349, 1991.
21. WALAAS, S. I., NAIRN, A. C., AND GREENGARD, P. Regional distribution of calcium- and cyclic adenosine 3′,5′-monophosphate-regulated protein phosphorylation systems in mammalian brain. I. Particulate systems. J. Neurosci. 3: 291-301, 1983.
22. A and glycine receptors-mediated responses of spinal neurons. Soc. Neurosci. Abstr. 21: 1841, 1995a.
23. WANG, R. A., CHENG, G., KOLAJ, M., AND RANDIĆ, M. α-Subunit of calcium/calmodulin-dependent protein kinase II enhances γ-aminobutyric acid and inhibitory synaptic responses of rat neurons in vitro. J. Neurophysiol 73: 2099-2106, 1995b.
24. WILLCOCKSON, W. S., CHUNG, J. M., HORI, Y., LEE, K. H., AND WILLIS, W. D. Effects of iontophoretically released amino acids and amines on primate spinothalmamic tract cells. J. Neurosci. 4: 732-740, 1984.
25. YOSHIMURA, M. AND NISHI, S. Primary afferent-evoked glycine- and GABA-mediated IPSPs in substantia gelatinosa neurones in the rat spinal cord in vitro. J. Physiol. Lond. 482: 29-38, 1995.