Identification of an inhibitory Zn2+ binding site on the human glycine receptor α1 subunit

Journal of Physiology

Volumn 520, Issue 1, 1999, Pages 53-64

  Harvey, Robert J ^a   Thomas, Philip ^a   James, Colin H ^a   Wilderspin, Andrew ^a   Smart, Trevor G ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DIETHYL PYROCARBONATE; GLYCINE RECEPTOR; HISTIDINE; RECEPTOR SUBUNIT; RECOMBINANT PROTEIN; ZINC ION; GLYCINE; GLYCINE RECEPTOR ALPHA1 SUBUNIT; UNCLASSIFIED DRUG; ZINC; GLYCINE RECEPTOR ALPHA1;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CONTROLLED STUDY; EMBRYO; EMBRYO CELL; EXTRACELLULAR MATRIX; GENE MUTATION; HUMAN; HUMAN CELL; HYDROPHOBICITY; ION CURRENT; KIDNEY CELL; MEMBRANE CURRENT; METAL BINDING; PH; PRIORITY JOURNAL; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS; CHANNEL GATING; EXTRACELLULAR SPACE; RECEPTOR DOWN REGULATION; AMINO ACID SEQUENCE; CELL LINE; CHEMICAL STRUCTURE; ELECTROPHYSIOLOGY; GENE VECTOR; GENETICS; METABOLISM; MOLECULAR GENETICS; PATCH CLAMP; PHYSIOLOGY;

AMINO ACID SEQUENCE; BINDING SITES; CELL LINE; DIETHYL PYROCARBONATE; ELECTROPHYSIOLOGY; EXTRACELLULAR MATRIX; GENETIC VECTORS; GLYCINE; HISTIDINE; HUMANS; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; RECEPTORS, GLYCINE; ZINC;

EID: 0033214678     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1999.00053.x     Document Type: Article

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