Protein-protein interactions in neurotransmitter release

Neuroscience Research

Volumn 36, Issue 3, 2000, Pages 175-182

  Mochida, Sumiko ^a  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Ca2+ channels; Exocytosis; Neurotransmitter release; Snare proteins; Synaptic terminal proteins; Synaptic vesicle

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; SNARE PROTEIN; SYNAPTOBREVIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25;

COMPLEX FORMATION; EXOCYTOSIS; HUMAN; MOLECULAR DYNAMICS; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REVIEW; SYNAPSE VESICLE; SYNAPTIC MEMBRANE;

EID: 0033981878     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(99)00128-5     Document Type: Article

References (79)

1. Augustine G.J., Burns M.E., DeBello W.M., Pettit D.L., Schweizer F.E. Exocytosis: proteins and perturbations. Annu. Rev. Pharmacol. Toxicol. 36:1996;659-701.
2. 2+-dependent exocytosis. J. Biol. Chem. 271:1996;20227-20230.
3. Bean A.J., Scheller R.H. Better late than never: a role for rabs late in exocytosis. Neuron. 19:1997;751-754.
4. Beites C.L., Xie H., Bowser R., Trimble W.S. The septin CDCrel-1 binds syntaxin and inhibits exocytosis. Nat. Neurosci. 2:1999;434-439.
5. Bennett M.K., Scheller R.H. The molecular machinery for secretion is conserved from yeast to neurons. Proc. Natl. Acad. Sci. USA. 90:1993;2559-2563.
6. Betz A., Okamoto M., Benseler F., Brose N. Direct interaction of the rat unc-13 homologue Munc13-1 with the N-terminal of syntaxin. J. Biol. Chem. 272:1997;2520-2526.
7. Betz A., Ashley U., Rickmann M. et al. Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release. Neuron. 21:1998;123-136.
8. Bezprozvanny I., Scheller R.H., Tsien R.W. Functional impact of syntaxin on gating of N-type and Q-type calcium channels. Nature. 378:1995;623-626.
9. Bommert K., Charton M.P., DeBello W.M. et al. Inhibition of neurotransmitter release by C2-domain peptides implicates synaptotagmin in exocytosis. Nature. 363:1993;163-165.
10. Broadie K., Prokop A., Bellen H.J. et al. Syntaxin and VAMP function downstream of vesicle docking in Drosophila. Neuron. 15:1995;663-673.
11. Brose N., Petrenko A.G., Südhof T.C., Jahn R. Synaptotagmin: a calcium sensor on the synaptic vesicle surface. Science. 256:1992;1021-1025.
12. Brose N., Hofmann K., Hata Y., Südhof T.C. Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins. J. Biol. Chem. 270:1995;25273-25280.
13. Burns E.M., Sasaki T., Takai Y., Augustine G.J. Rabphilin-3A: a multifunctional regulator of synaptic vesicle traffic. J. Gen. Physiol. 111:1998;243-255.
14. Castillo P.E., Janz R., Südhof T.C. et al. Rab3A is essential for mossy fibre long-term potentiation in the hippocampus. Nature. 388:1997;590-593.
15. Chapman E.R., An S., Barton N., Jahn R. SNAP-25, a t-SNARE which binds to both syntaxin and VAMP via domains that may form cioled coils. J. Biol. Chem. 269:1995a;27427-27432.
16. 2+ regulates the interaction between synaptotagmin and syntaxin 1. J. Biol. Chem. 270:1995b;23667-23671.
17. 2+ and drives membrane fusion. Cell. 97:1999;165-174.
18. 2+ and assembly with core snare complex onto membranes. Neuron. 24:1999;363-376.
19. DeBello W.M., O'Conner V., Dresbach T. et al. SNAP-mediated protein-protein interactions essential for neurotransmitter release. Nature. 373:1995;626-630.
20. Deitcher D.L., Ueda A., Stewart B.A. et al. Distinct requirements for evoked and spontaneous release of neurotransmitter are revealed by mutations in the Drosophila gene neuronal-VAMP. J. Neurosci. 18:1998;2028-2039.
21. Dresbach T., Burns M.E., O'Conner V. et al. A neuronal Sec1 homolog regulates neurotransmitter release at the squid giant synapse. J. Neurosci. 18:1998;2923-2932.
22. Ferro-Novick S., Jahn R. Vesicle fusion from yeast to man. Nature. 370:1994;191-193.
23. Fletcher A.I., Shuang R., Giovannucci D.R. et al. Regulation of exocytosis by cyclin-dependent kinase 5 via phosphorylatoin of munc-18. J. Biol. Chem. 274:1999;4027-4035.
24. Fujita Y., Shirataki H., Sakisaka T. et al. Tomosyn: a syntaxin-1-binding protein that forms a novel complex in the neurotransmitter process. Neuron. 20:1998a;905-915.
25. Fujita Y., Sasaki T., Fukui K. et al. Phosphorylation of munc-18/n-Sec1/rbSec1 by protein kinase C. J. Biol. Chem. 271:1998b;7265-7268.
26. Geppert M., Bolshakov V.Y., Siegelbaum S.A. et al. Role of the rab3A in neurotransmitter release. Nature. 369:1994;493-497.
27. 2+ sensor for transmitter release at a central synapse. Cell. 79:1994;717-727.
28. Geppert M., Goda Y., Stevens C.F., Südhof T.C. The small GTP-binding protein rab3A regulates a late step in synaptic vesicle fusion. Nature. 387:1997;810-814.
29. Gillis K.D., Möbner R., Neher E. Protein kinase C enhances exocytosis from chromaffin cells by increasing the size of the readily releasable pool of secretory granules. Neuron. 16:1996;1209-1220.
30. Hanson P.I., Heuser J.E., Jahn R. Neurotransmitter release - 4 years of SNARE complexes. Curr. Opin. Neurobiol. 7:1997;310-315.
31. Hayashi T., Yamasaki S., Nauenburg S., Binz T., Niemann H. Disassembly of the reconstituted synaptic vesicle membrane fusion complex in vitro. EMBO J. 14:1995;2317-2325.
32. Hirling H., Scheller R.H. Phosphorylation of synaptic vesicle proteins: modulation of the αSNAP interaction with the core complex. Proc. Natl. Acad. Sci. USA. 93:1996;11945-11949.
33. Hunt J.M., Bommert K., Charlton M.P. et al. A post-docking role for VAMP in synaptic vesicle fusion. Neuron. 12:1994;1269-1279.
34. Ilardi J.M., Mochida S., Sheng Z.-H. Snapin: a SNARE-associated protein implicated in synaptic transmission. Nat. Neurosci. 2:1999;119-124.
35. Lao, G., Scheuss, V., Gerwin, C.M., Su, Q., Mochida, S., Rettig, J., Sheng, Z.-H., 2000. Syntaphilin: a syntaxin-1 clamp that controls SNARE assembly. Neuron (In press).
36. 2+-dependent and -independent activities of neural and non neural synaptotagmins. Nature. 375:1994;594-599.
37. Lian J.P., Stone S., Jiang Y., Lyons P., Ferro-Novik S. Ypt1p implicated in v-SNARE activation. Nature. 372:1994;698-701.
38. Littleton J.T., Chapman E.R., Kreber R. et al. Temperature-sensitive paralytic mutations demonstrate that synaptic exocytosis requires SNARE complex assembly and disassembly. Neuron. 21:1998;401-413.
39. Littleton J.T., Serano T.L., Rubin G.M., Ganetzky B., Chapman E.R. Synaptic function modulated by changes in the ratio of synaptotagmin I and IV. Nature. 400:1999;757-760.
40. Lupashin V.V., Waters M.G. t-SNARE activation through transient interaction with rab-like guanosine triphosphate. Science. 276:1997;1255-1258.
41. Maruyama I.N., Brenner S. A phorbol ester/diacylglycerol-binding protein encoded by the unc-13 gene of Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA. 88:1991;5729-5733.
42. Matsui Y., Kikuchi A., Kondo J. et al. Nucleotide and deduced amino acid sequences of a GTP-binding protein family with molecular weights of 25000 from bovine brain. J. Biol. Chem. 263:1988;11071-11074.
43. McMahon H.T., Missler M., Li C., Südhof T.C. Complexins: cytosolic proteins that regulate SNAP receptor function. Cell. 83:1995;111-119.
44. Meffert M.K., Calakos N.C., Scheller R.H., Schulman H. Nitric oxide modulates synaptic vesicle docking/fusion reactions. Neuron. 16:1996;1229-1236.
45. Mikoshiba K., Fukuda M., Moreira J.E. et al. Role of the C2A domain of synaptotagmin in transmitter release as determined by specific antibody injection into the squid giant synapse terminal. Proc. Natl. Acad. Sci. USA. 92:1995;10703-10707.
46. 2+ channels. Neuron. 17:1996;781-788.
47. Mochida S., Fukuda M., Niinobe M., Kobayashi H., Mikoshiba K. Role of synaptotagmin C2 domains in neurotransmitter secretion and inositol high-polyphosphate binding at mammalian cholinergic synapses. Neuroscience. 77:1997;937-943.
48. Mochida S., Orita S., Sakaguchi G., Sasaki T., Takai Y. Role of the Doc2a-Munc-13-1 interaction in the neurotransmitter release process. Proc. Natl. Acad. Sci. USA. 95:1998a;11418-11422.
49. 2+ channels. Proc. Natl. Acad. Sci. USA. 95:1998b;14523-14528.
50. Monteccuco C., Schiavo G. Structure and function of tetanus and botulinum neurotoxins. Quart. Rev. Biophys. 28:1995;423-472.
51. Niemann H., Blasi J., Jahn R. Clostridial neurotoxins: new tools for dissecting exocytosis. Trens. Cell. Biol. 4:1994;179-185.
52. Ono S., Baux G., Sekiguchi M. et al. Regulatory roles of complexins in neurotransmitter release from mature presynaptic nerve terminals. Eur. J. Neurosci. 10:1998;2143-2152.
53. Orita S., Sasaki T., Komura R. et al. Molecular cloning of an isoform of Doc2 having two C2-like domains. Biochem. Biophys. Res. Commun. 206:1995;439-448.
54. 2+-dependent exocytosis machinery. J. Biol. Chem. 272:1997;16081-16084.
55. Pevsner J., Hsu S.-C., Braun J.E.A. et al. Specificity and regulation of a synaptic vesicle docking complex. Neuron. 13:1994;353-361.
56. 2+ channels with presynaptic proteins syntaxin and SNAP-25. Proc. Natl. Acad. Sci. USA. 93:1996;7363-7368.
57. 2+ channel/syntaxin interaction. J. Neurosci. 17:1997;6647-6656.
58. Rothman J.E. Mechanisms of intracellular protein transport. Nature. 372:1994;55-63.
59. Schiavo G., Stenbeck G., Rothman J.E., Söllner T.H. Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses. Proc. Natl. Acad. Sci. USA. 94:1997;997-1001.
60. Schülter O.M., Schnell E., Verhage M. et al. Rabphilin knock out mice reveal that rabphilin is not required for rab3 function in regulating neurotransmitter release. J. Neurosci. 19:1999;5834-5846.
61. Schulze K.L., Broadie K., Perin M.S., Bellen H.J. Genetic and electrophysiological studies of Drosophila syntaxin-1A demonstrate its role in nonneuronal secretion and neurotransmission. Cell. 80:1995;311-320.
62. 2+-dependent electrostatic switch. Neuron. 18:1997;133-142.
63. Sheng Z.-H., Rettig J., Takahashi M., Catterall W.A. Identification of a syntaxin-binding site on N-type calcium channels. Neuron. 13:1994;1303-1313.
64. Sheng Z.-H., Rettig J., Cook T., Catterall W.A. Calcium-dependent interaction of N-type calcium channels with the synaptic core-complex. Nature. 379:1994;451-454.
65. Shimazaki Y., Nishiki T., Omori A. et al. Phosphorylation of 25-kDa synaptosome-associated protein. J. Biol. Chem. 271:1996;14548-14553.
66. Shirataki H., Kaibuchi K., Sakoda T. et al. Rabphilin-3A, a putative target protein for smg p25/rab3A p25 small GTP-binding protein related to synaptotagmin. Mol. Cell. Biol. 13:1993;2061-2068.
67. Søgaard M., Tani K., Ye R.R. et al. A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles. Cell. 78:1994;937-948.
68. Söllner T., Whiteheat S.W., Brunner M. et al. SNAP receptors implicated in vesicle targeting and fusion. Nature. 362:1993a;318-324.
69. Söllner T., Bennett M.K., Whiteheat S.W., Scheller R.H., Rothman J.E. A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation and fusion. Cell. 75:1993b;409-418.
70. Südhof T.C. The synaptic vesicle cycle: a cascade of protein-protein interactions. Nature. 375:1995;645-653.
71. Sutton R.B., Fasshauer D., Jahn R., Brunger A.T. Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution. Nature. 395:1998;347-353.
72. Sweeney S.T., Broadie K., Keane J., Niemann H., O'Kane C.J. Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects. Neuron. 14:1995;341-351.
73. Takahashi S., Ujihara H., Huang G.-Z. et al. Reduced hippocampal LTP in mice lacking a presynaptic protein: complexin II. Eur. J. Neurosci. 11:1999;2359-2366.
74. Touchot N., Chardin P., Tavitian A. Four additional members of the ras gene superfamily isolated by an oligonucleotide strategy: molecular cloning of YPT-related cDNAs from a rat brain library. Proc. Natl. Acad. Sci. USA. 84:1987;8210-8214.
75. Wang Y., Okamoto M., Schmitz F., Hoffmann K., Südhof T.C. Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion. Nature. 388:1997;593-598.
76. Weber T., Zemelman B.V., McNew J.A. et al. SNAREpins: minimal machinery for membrane fusion. Cell. 92:1998;759-772.
77. 2+ channels. EMBO J. 15:1996;4100-4110.
78. Wu M.N., Fergestad T., Lloyed T.E. et al. Syntaxin 1A interacts with multiple exocytic proteins to regulate neurotransmitter release in vivo. Neuron. 23:1999;593-605.
79. Xu T., Binz T., Niemann H., Neher E. Multiple kinetic components of exocytosis distinguished by neurotoxin sensitivity. Natu. Neurosci. 1:1998;192-200.