-
6
-
-
0027254069
-
How many mutations are required for tumorigenesis? Implications from human cancer data
-
(1993)
Mol Carcinog
, vol.7
, pp. 139-146
-
-
Renan, M.J.1
-
7
-
-
0025773554
-
Mutator phenotype may be required for multistage carcinogenesis
-
(1991)
Cancer Res
, vol.51
, pp. 3075-3079
-
-
Loeb, L.A.1
-
11
-
-
0032546360
-
Mutations of mitotic checkpoint genes in human cancers
-
(1998)
Nature
, vol.392
, pp. 300-303
-
-
Cahill, D.P.1
Lengauer, C.2
Yu, J.3
Riggins, G.J.4
Willson, J.K.5
Markowitz, S.D.6
Kinzler, K.W.7
Vogelstein, B.8
-
12
-
-
0032514366
-
Chromosome number and structure both are markedly stable in RER colorectal cancers and are not destabilized by nmtation of p53
-
(1998)
Oncogene
, vol.17
, pp. 719-725
-
-
Eshleman, J.R.1
Casey, G.2
Kochera, M.E.3
Sedwick, W.D.4
Swinler, S.E.5
Veigl, M.L.6
Willson, J.K.7
Schwartz, S.8
Markowitz, S.D.9
-
13
-
-
0028951801
-
Deficiency of p55 accelerates mammary: Tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability
-
(1995)
Genes Dev
, vol.9
, pp. 882-895
-
-
Donehower, L.A.1
Godley, L.A.2
Aldaz, C.M.3
Pyle, R.4
Shi, Y.P.5
Pinkel, D.6
Gray, J.7
Bradley, A.8
Medina, D.9
Vannus, H.E.10
-
15
-
-
8544232096
-
Cytogenetic comparisons of synchronous carcinomas and polyps in patients with colorectal cancer
-
(1997)
Br J Cancer
, vol.76
, pp. 765-769
-
-
Bardi, G.1
Parada, L.A.2
Bomme, L.3
Pandis, N.4
Willen, R.5
Johansson, B.6
Jeppsson, B.7
Beroukas, K.8
Helm, S.9
Mitelman, F.10
-
16
-
-
0025634118
-
p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis
-
(1990)
Cancer Res
, vol.50
, pp. 7717-7722
-
-
Baker, S.J.1
Preisinger, A.C.2
Jessup, J.M.3
Paraskeva, C.4
Markowitz, S.5
Willson, J.K.6
Hamilton, S.7
Vogelstein, B.8
-
17
-
-
0033580430
-
Centrosome hyperamplification in hmnan cancer: Chromosome instability, induced by p53 mutation and/or Mdm2 overexpression
-
(1999)
Oncogene
, vol.18
, pp. 1935-1944
-
-
Carroll, P.E.1
Okuda, M.2
Horn, H.F.3
Biddinger, P.4
Stambrook, P.J.5
Gleich, L.L.6
Li, Y.Q.7
Tarapore, P.8
Fukasawa, K.9
-
24
-
-
0030894785
-
Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations
-
(1997)
Cancer Res
, vol.57
, pp. 1222-1227
-
-
Tirkkonen, M.1
-
26
-
-
0031472370
-
Association of BRCA1 with Rad51 in mitotic and meiotic cells
-
(1997)
Cell
, vol.88
, pp. 265-275
-
-
Scully, R.1
Chen, J.2
Plug, A.3
Xiao, Y.4
Weaver, D.5
Feunteun, J.6
Ashley, T.7
Livingston, D.M.8
-
27
-
-
0033106326
-
Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells
-
(1999)
Mol Cell
, vol.3
, pp. 389-395
-
-
Xu, X.1
Weaver, Z.2
Linke, S.P.3
Li, C.4
Gotay, J.5
Wang, X.W.6
Harris, C.C.7
Pied, T.8
Deng, C.X.9
-
28
-
-
0032587877
-
Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation
-
(1999)
Nat Genet
, vol.22
, pp. 37-43
-
-
Xu, X.1
Wagner, K.U.2
Larson, D.3
Weaver, Z.4
Li, C.5
Ried, T.6
Hennighausen, L.7
Wynshaw-Boris, A.8
Deng, C.X.9
-
29
-
-
0028073794
-
BRCA1 mutations in primary breast and ovarian carcinomas
-
(1994)
Science
, vol.266
, pp. 120-122
-
-
Futreal, P.A.1
-
30
-
-
0028960025
-
Somatic mutations in the BRCA1 gene in sporadic ovarian tumours
-
(1995)
Nat Genet
, vol.9
, pp. 439-443
-
-
Merajver, S.D.1
Pham, T.M.2
Caduff, R.F.3
Chen, M.4
Poy, E.L.5
Cooney, K.A.6
Weber, B.L.7
Collins, F.S.8
Johnston, C.9
Frank, T.S.10
-
41
-
-
0001294157
-
The stability of broken ends of chromosomes in Zea mays
-
(1941)
Genetics
, vol.26
, pp. 234-282
-
-
McClintock, B.1
-
42
-
-
0029096515
-
The RNA component of human telomerase
-
(1995)
Science
, vol.269
, pp. 1236-1241
-
-
Feng, J.1
-
44
-
-
0030668722
-
Human telomerase contains evolutionarily conserved catalytic and structural subunits
-
(1997)
Genes Dev
, vol.11
, pp. 3109-3115
-
-
Harrington, L.1
Zhou, W.2
McPhail, T.3
Oulton, R.4
Yeung, D.S.5
Mar, V.6
Bass, M.B.7
Robinson, M.O.8
-
45
-
-
0030681073
-
Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types
-
(1997)
Hum Mol Genet
, vol.6
, pp. 2011-2019
-
-
Kilian, A.1
Bowtell, D.D.2
Abud, H.E.3
Hime, G.R.4
Venter, D.J.5
Keese, P.K.6
Duncan, E.L.7
Reddel, R.R.8
Jefferson, R.A.9
-
46
-
-
0030745448
-
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
-
(1997)
Cell
, vol.90
, pp. 785-795
-
-
Meyerson, M.1
-
47
-
-
0030819894
-
Telomerase catalytic subunit homologs from fission yeast and human
-
(1997)
Science
, vol.277
, pp. 955-959
-
-
Nakamura, T.M.1
Morin, G.B.2
Chapman, K.B.3
Weinrich, S.L.4
Andrews, W.H.5
Lingner, J.6
Halley, C.B.7
Cech, T.R.8
-
49
-
-
0026460896
-
Telomere length predicts replicative capacity of human fibroblasts
-
(1992)
Proc Nad Acad Sci USA
, vol.89
, pp. 10114-10118
-
-
Allsopp, R.C.1
Vaziri, H.2
Patterson, C.3
Goldstein, S.4
Younglai, E.V.5
Futcher, A.B.6
Greider, C.W.7
Harley, C.B.8
-
50
-
-
0002309826
-
Tel omere dynamics and genomic instability in human cancer
-
(Blackburn EH, Greider CW, eds) Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
-
(1995)
Telomeres
, pp. 265-293
-
-
De Lange, T.1
-
52
-
-
0028673260
-
Telomerase, cell immortality, and cancer
-
(1994)
Cold Spring Harb. Symp. Quant. Biol.
, vol.59
, pp. 307-315
-
-
Harley, C.B.1
Kim, N.W.2
Prowse, K.R.3
Weinrich, S.L.4
Hirsch, K.S.5
West, M.D.6
Bacchetti, S.7
Hirte, H.W.8
Counter, C.M.9
Greider, C.W.10
-
54
-
-
0027486732
-
Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes
-
(1993)
Am J Hum Genet
, vol.52
, pp. 661-667
-
-
Vaziri, H.1
Schachter, F.2
Uchida, I.3
Wei, L.4
Zhu, X.5
Effors, R.6
Cohen, D.7
Harley, C.B.8
-
59
-
-
0024426688
-
Quantitation of the frequency of immortalization of normal human diploid fibroblasts by SV40 large T-antigen
-
(1989)
Exp Cell Res
, vol.184
, pp. 109-118
-
-
Shay, J.W.1
Wright, W.E.2
-
62
-
-
0010045614
-
Extension of life-span by introduction of telomerase into normal human cells
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.1
Ouellette, M.2
Frolkis, M.3
Holt, S.E.4
Chiu, C.P.5
Morin, G.B.6
Harley, C.B.7
Shay, J.W.8
Lichsteiner, S.9
Wright, W.E.10
-
63
-
-
0032567967
-
Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span
-
(1998)
Curr Biol
, vol.8
, pp. 279-282
-
-
Vaziri, H.1
Benchimol, S.2
-
64
-
-
0032440891
-
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 14723-14728
-
-
Counter, C.M.1
Hahn, W.C.2
Wei, W.3
Caddie, S.D.4
Beijersbergen, R.L.5
Lansdorp, P.M.6
Sedivy, J.M.7
Weinberg, R.A.8
-
67
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
(1994)
Science
, vol.266
, pp. 2011-2015
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
Harley, C.B.4
West, M.D.5
Ho, P.L.6
Coviello, G.M.7
Wright, W.E.8
Weinrich, S.L.9
Shay, J.W.10
-
70
-
-
0030950046
-
Telomere structure and telomerase expression during mouse development and tumorigenesis
-
(1997)
Eur J Cancer
, vol.33
, pp. 792-800
-
-
Kipling, D.1
-
74
-
-
0031308638
-
Genetic control of telomerase and replicative senescence in human and rodent cells
-
discussion 189
-
(1997)
Ciba Found. Symp.
, vol.211
, pp. 177-189
-
-
Newbold, R.F.1
-
81
-
-
0033525558
-
Longevity, stress response, and cancer in aging telomerase-deficient mice
-
(1998)
Cell
, vol.96
, pp. 701-712
-
-
Rudolph, K.L.1
Chang, S.2
Lee, H.W.3
Blasco, M.4
Gottlieb, G.J.5
Greider, C.6
DePinho, R.A.7
-
83
-
-
0031266691
-
Critical telomere shortening regulated by the ataxia-telangiectasia gene acts as a DNA damage signal leading to activation of p53 protein and limited life-span of human diploid fibroblasts
-
(1997)
Biochem (Mosc)
, vol.62
, pp. 1306-1310
-
-
Vaziri, H.1
-
84
-
-
0030761351
-
ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving only (ADP-ribose) polymerase
-
(1997)
EMBO J
, vol.16
, pp. 6018-6033
-
-
Vaziri, H.1
West, M.D.2
Allsopp, R.C.3
Davison, T.S.4
Wu, Y.S.5
Arrowsmith, C.H.6
Poirier, G.G.7
Benchimol, S.8
-
86
-
-
0032169516
-
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2
-
(1998)
EMBO J
, vol.17
, pp. 5001-5014
-
-
Stott, F.J.1
-
87
-
-
0033634973
-
DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway
-
(2000)
Mol Cell
, vol.5
, pp. 993-1002
-
-
Frank, K.M.1
Sharpless, N.E.2
Gao, Y.3
Sekiguchi, J.M.4
Ferguson, D.O.5
Zhu, C.6
Manis, J.P.7
Horner, J.8
DePinho, R.A.9
Alt, F.W.10
-
88
-
-
0030728468
-
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
Zindy, F.2
Roussel, M.F.3
Quelle, D.E.4
Downing, J.R.5
Ashmun, R.A.6
Grosveld, G.7
Sherr, C.J.8
-
89
-
-
0000146723
-
2/3 cancer-prone mouse
-
(1999)
Cell
, vol.97
, pp. 515-525
-
-
Greenberg, R.A.1
Chin, L.2
Femino, A.3
Lee, K.H.4
Gottlieb, G.J.5
Singer, R.H.6
Greider, C.W.7
DePinho, R.A.8
-
92
-
-
0033553516
-
p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
-
(1999)
Cell
, vol.97
, pp. 527-538
-
-
Chin, L.1
Artandi, S.E.2
Shen, Q.3
Tam, A.4
Lee, S.L.5
Gottlieb, G.J.6
Greider, C.W.7
DePinho, R.A.8
-
94
-
-
0038214755
-
Multicolor spectral karyotyping of human chromosomes
-
(1996)
Science
, vol.273
, pp. 494-497
-
-
Schrock, E.1
-
95
-
-
16144368671
-
Mnlticolour spectral karyotyping of mouse chromosomes
-
(1996)
Nat Genet
, vol.14
, pp. 312-315
-
-
Liyanage, M.1
-
99
-
-
0033833422
-
p53 gene status and expression of p53, mdm2, and p21Waf1/Cip1 proteins in colorectal cancer
-
(2000)
Virchows Arch
, vol.437
, pp. 241-247
-
-
Veloso, M.1
Wrba, F.2
Kaserer, K.3
Heinze, G.4
Magalhaes, A.5
Herbst, F.6
Teleky, B.7
-
101
-
-
17344371740
-
High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays
-
(1998)
Nat Genet
, vol.20
, pp. 207-211
-
-
Pinkel, D.1
-
102
-
-
0032823523
-
Genome-wide analysis of DNA copy-number changes using cDNA microarrays
-
(1999)
Nat Genet
, vol.23
, pp. 41-46
-
-
Pollack, J.R.1
Perou, C.M.2
Alizadeh, A.A.3
Eisen, M.B.4
Pergamenschikov, A.5
Williams, C.F.6
Jeffrey, S.S.7
Botstein, D.8
Brown, P.O.9
-
103
-
-
0034129516
-
Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene
-
(2000)
Nat Genet
, vol.25
, pp. 144-146
-
-
Albertson, D.G.1
Ylstra, B.2
Segraves, R.3
Collins, C.4
Dairkee, S.H.5
Kowbel, D.6
Kuo, W.L.7
Gray, J.W.8
Pinkel, D.9
-
109
-
-
0032980789
-
Comparative genomic hybridization of ductal carcinoma in situ of the breast - Evidence of multiple genetic pathways
-
(1999)
J Pathol
, vol.187
, pp. 396-402
-
-
Buerger, H.1
Otterbach, F.2
Simon, R.3
Poremba, C.4
Diallo, R.5
Decker, T.6
Riethdorf, L.7
Brinkschmidt, C.8
Dockhorn-Dworniczak, B.9
Boecker, W.10
|