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Volumn 6, Issue 12, 1997, Pages 2011-2019

Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; REPETITIVE DNA; RNA DIRECTED DNA POLYMERASE; TELOMERASE;

EID: 0030681073     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/6.12.2011     Document Type: Article
Times cited : (539)

References (49)
  • 1
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
    • Greider, C.W. and Blackburn, E.H. (1985) Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell, 43, 405-413.
    • (1985) Cell , vol.43 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.H.2
  • 2
    • 0031000884 scopus 로고    scopus 로고
    • Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening
    • Makarov, V.L., Hirose, Y. and Langmore, J.P. (1997) Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening. Cell, 88, 657-666.
    • (1997) Cell , vol.88 , pp. 657-666
    • Makarov, V.L.1    Hirose, Y.2    Langmore, J.P.3
  • 3
    • 0015184804 scopus 로고
    • Principle of marginotomy in template synthesis of polynucleotides
    • Olovnikov, A.M. (1971) Principle of marginotomy in template synthesis of polynucleotides. Doklady Akademii Nauk SSR, 201, 1496-1499.
    • (1971) Doklady Akademii Nauk SSR , vol.201 , pp. 1496-1499
    • Olovnikov, A.M.1
  • 4
    • 0015844590 scopus 로고
    • A theory of marginotomy
    • Olovnikov, A.M. (1973) A theory of marginotomy. J. Theor. Biol., 41, 181-190.
    • (1973) J. Theor. Biol. , vol.41 , pp. 181-190
    • Olovnikov, A.M.1
  • 6
    • 0029066169 scopus 로고
    • Telomerase activity in normal and malignant hematopoietic cells
    • Broccoli, D., Young, J.W. and de Lange, T. (1995) Telomerase activity in normal and malignant hematopoietic cells. Proc. Natl. Acad. Sci. USA, 92, 9082-9086.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 9082-9086
    • Broccoli, D.1    Young, J.W.2    De Lange, T.3
  • 7
    • 0028938262 scopus 로고
    • Telomerase activity in normal leukocytes and in hematologic malignancies
    • Counter, C.M., Gupta, J., Harley, C.B., Leber, B. and Bacchetti, S. (1995) Telomerase activity in normal leukocytes and in hematologic malignancies. Blood, 85, 2315-2320.
    • (1995) Blood , vol.85 , pp. 2315-2320
    • Counter, C.M.1    Gupta, J.2    Harley, C.B.3    Leber, B.4    Bacchetti, S.5
  • 9
    • 0029901910 scopus 로고    scopus 로고
    • Telomerase activity in the regenerative basal layer of the epidermis in human skin and in immortal and carcinoma-derived skin keratinocytes
    • Härle-Bachor, C. and Boukamp, P. (1996) Telomerase activity in the regenerative basal layer of the epidermis in human skin and in immortal and carcinoma-derived skin keratinocytes. Proc. Natl. Acad. Sci. USA, 93, 6476-6481.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 6476-6481
    • Härle-Bachor, C.1    Boukamp, P.2
  • 12
    • 0026523228 scopus 로고
    • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
    • Counter, C.M., Avilion, A.A., LeFeuvre, C.E., Stewart, N.G., Greider, C.W., Harley, C.B. and Bacchetti, S. (1992) Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J., 11, 1921-1929.
    • (1992) EMBO J. , vol.11 , pp. 1921-1929
    • Counter, C.M.1    Avilion, A.A.2    LeFeuvre, C.E.3    Stewart, N.G.4    Greider, C.W.5    Harley, C.B.6    Bacchetti, S.7
  • 13
    • 0028322713 scopus 로고
    • SV40-induced immortalization of human cells
    • Bryan, T.M. and Reddel, R.R. (1994) SV40-induced immortalization of human cells. Crit. Rev. Oncogenesis, 5, 331-357.
    • (1994) Crit. Rev. Oncogenesis , vol.5 , pp. 331-357
    • Bryan, T.M.1    Reddel, R.R.2
  • 14
    • 0028140264 scopus 로고
    • Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells
    • Klingelhutz, A.J., Barber, S.A., Smith, P.P., Dyer, K. and McDougall, J.K. (1994) Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells. Mol. Cell. Biol., 14, 961-969.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 961-969
    • Klingelhutz, A.J.1    Barber, S.A.2    Smith, P.P.3    Dyer, K.4    McDougall, J.K.5
  • 15
    • 0028198679 scopus 로고
    • Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes
    • Counter, C.M., Botelho, F.M., Wang, P., Harley, C.B. and Bacchetti, S. (1994) Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes. J. Virol., 68, 3410-3414.
    • (1994) J. Virol. , vol.68 , pp. 3410-3414
    • Counter, C.M.1    Botelho, F.M.2    Wang, P.3    Harley, C.B.4    Bacchetti, S.5
  • 16
    • 0029162563 scopus 로고
    • Telomere elongation in immortal human cells without detectable telomerase activity
    • Bryan, T.M., Englezou, A., Gupta, J., Bacchetti, S. and Reddel, R.R. (1995) Telomere elongation in immortal human cells without detectable telomerase activity. EMBO J., 14, 4240-4248.
    • (1995) EMBO J. , vol.14 , pp. 4240-4248
    • Bryan, T.M.1    Englezou, A.2    Gupta, J.3    Bacchetti, S.4    Reddel, R.R.5
  • 17
    • 12644258520 scopus 로고    scopus 로고
    • Telomerase activation during the linear evolution of human fibroblasts to tumorigenicity in nude mice
    • Montalto, M.C. and Ray, F.A. (1996) Telomerase activation during the linear evolution of human fibroblasts to tumorigenicity in nude mice. Carcinogenesis, 17, 2631-2634.
    • (1996) Carcinogenesis , vol.17 , pp. 2631-2634
    • Montalto, M.C.1    Ray, F.A.2
  • 18
    • 0024325562 scopus 로고
    • The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
    • Morin, G.B. (1989) The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell, 59, 521-529.
    • (1989) Cell , vol.59 , pp. 521-529
    • Morin, G.B.1
  • 21
    • 0031010342 scopus 로고    scopus 로고
    • A survey of telomerase activity in human cancer
    • Shay, J.W. and Bacchetti, S. (1997) A survey of telomerase activity in human cancer. Eur. J. Cancer, 33A, 787-791.
    • (1997) Eur. J. Cancer , vol.33 A , pp. 787-791
    • Shay, J.W.1    Bacchetti, S.2
  • 22
    • 0029649685 scopus 로고
    • Is telomerase a universal cancer target?
    • Morin, G.B. (1995) Is telomerase a universal cancer target? J. Natl. Cancer Inst., 87, 859-861.
    • (1995) J. Natl. Cancer Inst. , vol.87 , pp. 859-861
    • Morin, G.B.1
  • 23
    • 0028007237 scopus 로고
    • Telomere dynamics in an immortal human cell line
    • Murnane, J.P., Sabatier, L., Marder, B.A. and Morgan, W.F. (1994) Telomere dynamics in an immortal human cell line. EMBO J., 13, 4953-4962.
    • (1994) EMBO J. , vol.13 , pp. 4953-4962
    • Murnane, J.P.1    Sabatier, L.2    Marder, B.A.3    Morgan, W.F.4
  • 24
    • 0030990049 scopus 로고    scopus 로고
    • Telomere dynamics and telomerase activity in in vitro immortalised human cells
    • Bryan, T.M. and Reddel, R.R. (1997) Telomere dynamics and telomerase activity in in vitro immortalised human cells. Eur. J. Cancer, 33A, 767-773.
    • (1997) Eur. J. Cancer , vol.33 A , pp. 767-773
    • Bryan, T.M.1    Reddel, R.R.2
  • 25
    • 0029746495 scopus 로고    scopus 로고
    • Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase
    • McEachem, M.J. and Blackburn, E.H. (1996) Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase. Genes Der., 10, 1822-1834.
    • (1996) Genes Der. , vol.10 , pp. 1822-1834
    • McEachem, M.J.1    Blackburn, E.H.2
  • 26
    • 0030697342 scopus 로고    scopus 로고
    • Evidence for an alternative mechanism for maintaining telomere length in human tumours and tumour-derived cell lines
    • in press
    • Bryan,T.M., Englezou, A., Dalla-Pozza, L., Dunham, M.A. and Reddel, R.R. (1997) Evidence for an alternative mechanism for maintaining telomere length in human tumours and tumour-derived cell lines. Nature Med., (in press).
    • (1997) Nature Med.
    • Bryan, T.M.1    Englezou, A.2    Dalla-Pozza, L.3    Dunham, M.A.4    Reddel, R.R.5
  • 28
    • 0029154735 scopus 로고
    • Functional characterization and developmental regulation of mouse telomerase RNA
    • Blasco, M.A., Funk, W., Villeponteau, B. and Greider, C.W. (1995) Functional characterization and developmental regulation of mouse telomerase RNA. Science, 269, 1267-1270.
    • (1995) Science , vol.269 , pp. 1267-1270
    • Blasco, M.A.1    Funk, W.2    Villeponteau, B.3    Greider, C.W.4
  • 29
    • 0030898989 scopus 로고    scopus 로고
    • TLPI: A gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family
    • Nakayama, J.-I., Saito, M., Nakamura, H., Matsuura, A. and Ishikawa, F. (1997) TLPI: A gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family. Cell, 88, 1-20.
    • (1997) Cell , vol.88 , pp. 1-20
    • Nakayama, J.-I.1    Saito, M.2    Nakamura, H.3    Matsuura, A.4    Ishikawa, F.5
  • 31
  • 33
    • 0022552131 scopus 로고
    • Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
    • Kozak, M. (1986) Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell, 44, 283-292.
    • (1986) Cell , vol.44 , pp. 283-292
    • Kozak, M.1
  • 34
    • 0028197552 scopus 로고
    • Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors
    • Giguere, V., Tini, M., Flock, G., Ong, E., Evans, R.M. and Otulakowski, G. (1994) Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors. Genes Dev., 8, 538-553.
    • (1994) Genes Dev. , vol.8 , pp. 538-553
    • Giguere, V.1    Tini, M.2    Flock, G.3    Ong, E.4    Evans, R.M.5    Otulakowski, G.6
  • 35
    • 0030610078 scopus 로고    scopus 로고
    • Murine laminin alpha3A and alpha3B isoform chains are generated by usage of two promoters and alternative splicing
    • Ferrigno, O., Virolle, T., Galliano, M.F., Chauvin, N., Ortonne, J.P., Meneguzzi, G. and Aberdam, D. (1997) Murine laminin alpha3A and alpha3B isoform chains are generated by usage of two promoters and alternative splicing. J. Biol. Chem., 272, 20502-20507.
    • (1997) J. Biol. Chem. , vol.272 , pp. 20502-20507
    • Ferrigno, O.1    Virolle, T.2    Galliano, M.F.3    Chauvin, N.4    Ortonne, J.P.5    Meneguzzi, G.6    Aberdam, D.7
  • 36
    • 0030795098 scopus 로고    scopus 로고
    • The rat pyruvate carboxylase gene structure. Alternate promoters generate multiple transcripts with the 5′-end heterogeneity
    • Jitrapakdee, S., Booker, G.W., Cassady, A.I. and Wallace, J.C. (1997) The rat pyruvate carboxylase gene structure. Alternate promoters generate multiple transcripts with the 5′-end heterogeneity. J. Biol. Chem., 272, 20522-20530.
    • (1997) J. Biol. Chem. , vol.272 , pp. 20522-20530
    • Jitrapakdee, S.1    Booker, G.W.2    Cassady, A.I.3    Wallace, J.C.4
  • 37
    • 0008563256 scopus 로고
    • Human basic fibroblast growth factor gene encodes four polypeptides: Three initiate translation from non-AUG codons
    • Florkiewich, R.V. and Sommer. A. (1989) Human basic fibroblast growth factor gene encodes four polypeptides: three initiate translation from non-AUG codons. Proc. Natl. Acad. Sci. USA, 86, 3978-3981.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 3978-3981
    • Florkiewich, R.V.1    Sommer, A.2
  • 38
    • 0030755955 scopus 로고    scopus 로고
    • Protein phosphatase 2A inhibits nuclear telomerase activity in human breast cancer cells
    • Li, H., Zhao, L.-L., Funder, J.W. and Liu, J.-P. (1997) Protein phosphatase 2A inhibits nuclear telomerase activity in human breast cancer cells. J. Biol. Chem., 272, 16729-16732.
    • (1997) J. Biol. Chem. , vol.272 , pp. 16729-16732
    • Li, H.1    Zhao, L.-L.2    Funder, J.W.3    Liu, J.-P.4
  • 40
    • 0025048136 scopus 로고
    • The P-loop - A common motif in ATP- and GTP-binding proteins
    • Saraste, M., Sibbald, P.R. and Wittinghoffer, A. (1990) The P-loop - a common motif in ATP- and GTP-binding proteins. Trends Biochem. Sci., 15, 430-434.
    • (1990) Trends Biochem. Sci. , vol.15 , pp. 430-434
    • Saraste, M.1    Sibbald, P.R.2    Wittinghoffer, A.3
  • 41
    • 0021760092 scopus 로고
    • A comprehensive set of sequence analysis programs for the VAX
    • Devereaux, J., Haeberli, P. and Smithies, O. (1984) A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res., 12, 387-395.
    • (1984) Nucleic Acids Res. , vol.12 , pp. 387-395
    • Devereaux, J.1    Haeberli, P.2    Smithies, O.3
  • 42
    • 0030916582 scopus 로고    scopus 로고
    • The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit
    • Bryan, T.M., Marusic, L., Bacchetti, S., Namba, M. and Reddel, R.R. (1997) The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit. Hum. Mol. Genet., 6, 921-926.
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 921-926
    • Bryan, T.M.1    Marusic, L.2    Bacchetti, S.3    Namba, M.4    Reddel, R.R.5
  • 43
    • 0029890441 scopus 로고    scopus 로고
    • Biochemistry and regulation of pre-mRNA splicing
    • Adams, M.D., Rudner, D.Z. and Rio, D.C. (1996) Biochemistry and regulation of pre-mRNA splicing. Curr. Opin. Cell Biol., 8, 331-339.
    • (1996) Curr. Opin. Cell Biol. , vol.8 , pp. 331-339
    • Adams, M.D.1    Rudner, D.Z.2    Rio, D.C.3
  • 45
    • 0030067487 scopus 로고    scopus 로고
    • Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues
    • Avilion, A.A., Piatyszek, M.A., Gupta, J., Shay, J.W., Bacchetti, S. and Greider, C.W. (1996) Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues. Cancer Res., 56, 645-650.
    • (1996) Cancer Res. , vol.56 , pp. 645-650
    • Avilion, A.A.1    Piatyszek, M.A.2    Gupta, J.3    Shay, J.W.4    Bacchetti, S.5    Greider, C.W.6
  • 46
    • 0027284301 scopus 로고
    • Similar simian virus 40-induced immortalization frequency of fibroblasts and epithelial cells from human large airways
    • De Silva, R. and Reddel, R.R. (1993) Similar simian virus 40-induced immortalization frequency of fibroblasts and epithelial cells from human large airways. Cell. Mol. Biol. Res., 39, 101-110.
    • (1993) Cell. Mol. Biol. Res. , vol.39 , pp. 101-110
    • De Silva, R.1    Reddel, R.R.2
  • 48
    • 0029152189 scopus 로고
    • cRACE: A simple method for identification of the 5′ end of mRNAs
    • Maruyama, I.N., Rakow, T.L. and Maruyama, H.I. (1995) cRACE: a simple method for identification of the 5′ end of mRNAs. Nucleic Acids Res., 23, 3796-3797.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 3796-3797
    • Maruyama, I.N.1    Rakow, T.L.2    Maruyama, H.I.3
  • 49
    • 0027968068 scopus 로고
    • CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
    • Thompson, J.D., Higgins, D.G. and Gibson. T.J. (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res., 22, 4673-4680.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3


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